#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q04779	intact:EBI-15670677	intact:EBI-28153|uniprotkb:D6VZP9|ensemblfungi:YMR075W	dip:DIP-46193N	psi-mi:rco1_yeast(display_long)|uniprotkb:YM9916.14(orf name)|uniprotkb:YMR075W(locus name)|uniprotkb:RCO1(gene name)|psi-mi:RCO1(display_short)	psi-mi:h3k27me(display_short)|psi-mi:EBI-15670677(display_long)	psi-mi:"MI:0096"(pull down)	Venkatesh et al. (2012)	pubmed:22914091|doi:10.1038/nature11326|imex:IM-18072	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16010171|imex:IM-18072-1|dip:DIP-189737E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_013791.1|sgd:S000004680|dip:DIP-1959N|mint:Q04779|ensemblfungi:YMR075W(gene)|ensemblfungi:YMR075W_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787	-	psi-mi:"MI:0465"(dip)	crc64:CFC282DC9A782E5C	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:5TrczzmnA5cA2yFTxM2rueJyA8c559292	rogid:CLcF0X0dlq40SE0taedCQRq6q84-2	rigid:dFJjUrxDPPz3RrTT9WsgaMTEJds	false	tandem tag:c-c	biotin tag:0-0	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32558	intact:EBI-15670677	intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8	dip:DIP-46193N	psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym)	psi-mi:h3k27me(display_short)|psi-mi:EBI-15670677(display_long)	psi-mi:"MI:0096"(pull down)	Venkatesh et al. (2012)	pubmed:22914091|doi:10.1038/nature11326|imex:IM-18072	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16010193|imex:IM-18072-2|dip:DIP-189739E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955	-	psi-mi:"MI:0465"(dip)	crc64:4F01C772E299E2E6	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292	rogid:CLcF0X0dlq40SE0taedCQRq6q84-2	rigid:87BxxEvAmm3LlqXv2jY/ZUEC9tg	false	tandem tag:c-c	biotin tag:0-0|N6,N6,N6-trimethyl-L-lysine:16-16	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32447	intact:EBI-15670677	intact:EBI-3003|uniprotkb:D6VW69|ensemblfungi:YJL115W	dip:DIP-46193N	psi-mi:asf1_yeast(display_long)|uniprotkb:ASF1(gene name)|psi-mi:ASF1(display_short)|uniprotkb:YJL115W(locus name)|uniprotkb:J0755(orf name)|uniprotkb:CIA1(gene name synonym)|uniprotkb:Anti-silencing function protein 1(gene name synonym)	psi-mi:h3k27me(display_short)|psi-mi:EBI-15670677(display_long)	psi-mi:"MI:0096"(pull down)	Venkatesh et al. (2012)	pubmed:22914091|doi:10.1038/nature11326|imex:IM-18072	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16010218|imex:IM-18072-3|dip:DIP-189738E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_012420.1|sgd:S000003651|dip:DIP-2675N|mint:P32447|ensemblfungi:YJL115W(gene)|ensemblfungi:YJL115W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006348"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0070775"(H3 histone acetyltransferase complex)|go:"GO:0097043"(histone H3-K56 acetylation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR017282(Histone deposition protein Asf1)|interpro:IPR036747|rcsb pdb:1ROC|rcsb pdb:1WG3|rcsb pdb:2HUE|rcsb pdb:2IDC|rcsb pdb:2YGV|rcsb pdb:4EO5|rcsb pdb:4ZBJ|rcsb pdb:5EII|rcsb pdb:5UCB|rcsb pdb:5UEA|rcsb pdb:5UEK|rcsb pdb:6AYZ|rcsb pdb:6AZ2|rcsb pdb:6F0Y|rcsb pdb:6O22|reactome:R-SCE-2559584	-	psi-mi:"MI:0465"(dip)	crc64:186E76075C0B1644	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:En27z1xiUMZBu18Nq9rrAsUy5Zs559292	rogid:CLcF0X0dlq40SE0taedCQRq6q84-2	rigid:/uJcFzhWsbHXYgxVf8DEbaGSV2k	false	tandem tag:c-c	biotin tag:0-0|N6,N6-dimethyl-L-lysine:16-16|N6,N6,N6-trimethyl-L-lysine:16-16	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P23615	intact:EBI-15670677	intact:EBI-17947|uniprotkb:D6VUP7|ensemblfungi:YGR116W	dip:DIP-46193N	psi-mi:spt6_yeast(display_long)|uniprotkb:CRE2(gene name synonym)|uniprotkb:SPT6(gene name)|psi-mi:SPT6(display_short)|uniprotkb:SSN20(gene name synonym)|uniprotkb:YGR116W(locus name)|uniprotkb:G6169(orf name)|uniprotkb:Chromatin elongation factor SPT6(gene name synonym)	psi-mi:h3k27me(display_short)|psi-mi:EBI-15670677(display_long)	psi-mi:"MI:0096"(pull down)	Venkatesh et al. (2012)	pubmed:22914091|doi:10.1038/nature11326|imex:IM-18072	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16010245|imex:IM-18072-4|dip:DIP-189740E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_011631.1|sgd:S000003348|ensemblfungi:YGR116W(gene)|ensemblfungi:YGR116W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000414"(regulation of histone H3-K36 methylation)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001073"(transcription antitermination factor activity, DNA binding)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070827"(obsolete chromatin maintenance)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR000980(SH2 motif)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR023319|interpro:IPR023323|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR042066|rcsb pdb:2L3T|rcsb pdb:3OAK|rcsb pdb:3PSF|rcsb pdb:3PSI|rcsb pdb:3PSJ|rcsb pdb:3PSK|rcsb pdb:5VKL|rcsb pdb:5VKO|reactome:R-SCE-674695|reactome:R-SCE-75955|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|dip:DIP-2630N|mint:P23615	-	psi-mi:"MI:0465"(dip)	crc64:0BE9922A59BD0483	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:P9a7UCjdCVTSPp8jVc5NjDP4FZk559292	rogid:CLcF0X0dlq40SE0taedCQRq6q84-2	rigid:uNfW9YfAp07NM03c8ORjvdTitco	false	flag tag:c-c	biotin tag:0-0|N6,N6,N6-trimethyl-L-lysine:16-16	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)