#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06929 uniprotkb:P18848 intact:EBI-7463272|intact:MINT-154028 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501553|imex:IM-28562-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:ST6|comment:"Normalized luminescence ratios: 12.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:vVdbuAUPZN+nFZIOa8XihVphRaY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P36507 intact:EBI-7463272|intact:MINT-154028 intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501564|imex:IM-28562-1081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 12.70"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606 rigid:DWBIouIio7711drI/fam7uVTTYU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O75528 intact:EBI-7463272|intact:MINT-154028 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501641|imex:IM-28562-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 23.41"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:rQDvV7hGE2UU+xJAdpb1O1FTYyY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q15582 intact:EBI-7463272|intact:MINT-154028 intact:EBI-10236573|uniprotkb:D3DQB1|uniprotkb:O43218|uniprotkb:O43217|uniprotkb:O14476|uniprotkb:O14472|uniprotkb:O43216|uniprotkb:O43219|uniprotkb:Q53XM1|uniprotkb:O14471|ensembl:ENSP00000416330 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:bgh3_human(display_long)|uniprotkb:TGFBI(gene name)|psi-mi:TGFBI(display_short)|uniprotkb:BIGH3(gene name synonym)|uniprotkb:Kerato-epithelin(gene name synonym)|uniprotkb:RGD-containing collagen-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501652|imex:IM-28562-943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000349.1|interpro:IPR032954|interpro:IPR036378|rcsb pdb:1X3B|rcsb pdb:2LTB|rcsb pdb:2LTC|rcsb pdb:2VXP|rcsb pdb:5NV6|rcsb pdb:7AS7|rcsb pdb:7ASC|rcsb pdb:7ASG|reactome:R-HSA-977225|ensembl:ENSG00000120708(gene)|ensembl:ENST00000442011(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR011489(EMI)|interpro:IPR016666(TGF beta-induced protein bIGH3/osteoblast-specific factor 2) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 28.60"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:86Kh2QpWO6GxkrQsjbtqcBrKs4M9606 rigid:wlVks3tNxmM1YA2B6jLJHU1ckL4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O95905 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501619|imex:IM-28562-741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 16.13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606 rigid:u+JuSZQrxRDnaRQXpsold6viCKk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O00303 intact:EBI-7463272|intact:MINT-154028 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501608|imex:IM-28562-1083 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 15.97"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 rigid:AWCEZ36Dxmvynd12o0s9gfYd+9s false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O95551 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501597|imex:IM-28562-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 15.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:A3a29kLH9qm6NNJxb1X+IyUL7Oc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P35250 uniprotkb:P06929 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 intact:EBI-7463272|intact:MINT-154028 psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501586|imex:IM-28562-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 - - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA figure legend:ST6|comment:"Normalized luminescence ratios: 13.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rigid:8WrkDqqdvfHv2Y++oyLdqzPnRbo false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P05549 intact:EBI-7463272|intact:MINT-154028 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501575|imex:IM-28562-941 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 13.00"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:6ZuNgbCGEb9bY8pryhBMQ5RKmxE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q6P9H4 intact:EBI-7463272|intact:MINT-154028 intact:EBI-10253274|uniprotkb:Q96N65|uniprotkb:Q5SGD5|uniprotkb:C9IZX4|ensembl:ENSP00000475915 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cnkr3_human(display_long)|uniprotkb:CNKSR3(gene name)|psi-mi:CNKSR3(display_short)|uniprotkb:CNK homolog protein 3(gene name synonym)|uniprotkb:CNKSR family member 3(gene name synonym)|uniprotkb:MAGI1(gene name synonym)|uniprotkb:Maguin-like protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501729|imex:IM-28562-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_775786.2|ensembl:ENSG00000153721(gene)|ensembl:ENST00000607772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.36"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:XblyCRyMkFkCnL104LVme415sSc9606 rigid:uNAvczNEq+9lxdKmPG5Wqb6EIxk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P53041 intact:EBI-7463272|intact:MINT-154028 intact:EBI-716663|uniprotkb:Q53XV2|uniprotkb:Q16722|ensembl:ENSP00000012443 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ppp5_human(display_long)|uniprotkb:Protein phosphatase T(gene name synonym)|uniprotkb:PPP5C(gene name)|psi-mi:PPP5C(display_short)|uniprotkb:PPP5(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501718|imex:IM-28562-947 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006238.1|ensembl:ENSG00000011485(gene)|ensembl:ENST00000012443(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0101031"(chaperone complex)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1904550"(response to arachidonic acid)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011236(Protein phosphatase 5)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013235(Serine/threonine phosphatase, PPP5)|interpro:IPR019734|interpro:IPR029052|interpro:IPR041753|mint:P53041|rcsb pdb:1A17|rcsb pdb:1S95|rcsb pdb:1WAO|rcsb pdb:2BUG|rcsb pdb:3H60|rcsb pdb:3H61|rcsb pdb:3H62|rcsb pdb:3H63|rcsb pdb:3H64|rcsb pdb:3H66|rcsb pdb:3H67|rcsb pdb:3H68|rcsb pdb:3H69|rcsb pdb:4ZVZ|rcsb pdb:4ZX2|rcsb pdb:5HPE|rcsb pdb:5UI1|rcsb pdb:5WG8|reactome:R-HSA-5675221|reactome:R-HSA-5693565|reactome:R-HSA-8939211|dip:DIP-29043N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:5QoNB467ftOvWaUNfSm6RalR8+Y9606 rigid:k1c0C5a/nc2hS28+G6eybvk7Dcw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P50616 intact:EBI-7463272|intact:MINT-154028 intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501707|imex:IM-28562-945 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.10"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606 rigid:ged8Wv/990YAPNDY+hwPk2F2nUc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q96EK4 intact:EBI-7463272|intact:MINT-154028 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501696|imex:IM-28562-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 4.09"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:9gH40DcuUxUZjvdYpPrNabxKoVI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q92905 intact:EBI-7463272|intact:MINT-154028 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501685|imex:IM-28562-1101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.93"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 rigid:ez/qd8xgDLAK6C20aZ+il1VyCNY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q92985 intact:EBI-7463272|intact:MINT-154028 intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501674|imex:IM-28562-1241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.70"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606 rigid:tJcdAwo795iUsVuxilH8enZHdDg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9NP84 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2851995|uniprotkb:Q9HCS0|uniprotkb:D3DUA6|ensembl:ENSP00000326737 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tnr12_human(display_long)|uniprotkb:TNFRSF12A(gene name)|psi-mi:TNFRSF12A(display_short)|uniprotkb:FN14(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible immediate-early response protein 14(gene name synonym)|uniprotkb:Tweak-receptor(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501663|imex:IM-28562-1085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057723.1|ensembl:ENSG00000006327(gene)|ensembl:ENST00000326577(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR022316|rcsb pdb:2EQP|rcsb pdb:2KMZ|rcsb pdb:2RPJ|reactome:R-HSA-5668541|reactome:R-HSA-5676594 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.62"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Dt8beNQk0ZQIvgZNCOWKnMvO/+g9606 rigid:Um5zSNzxITAsy0E8c+ZmoypsIrs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O00762 intact:EBI-7463272|intact:MINT-154028 intact:EBI-719691|uniprotkb:A6NP33|uniprotkb:E1P5N7|uniprotkb:G3XAB7|ensembl:ENSP00000348838 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube2c_human(display_long)|uniprotkb:Ubiquitin-protein ligase C(gene name synonym)|uniprotkb:Ubiquitin carrier protein C(gene name synonym)|uniprotkb:UbcH10(gene name synonym)|uniprotkb:UBE2C(gene name)|psi-mi:UBE2C(display_short)|uniprotkb:UBCH10(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme C"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme C(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501630|imex:IM-28562-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_008950.1|refseq:NP_861515.1|refseq:NP_861516.1|refseq:NP_861517.1|ensembl:ENSG00000175063(gene)|ensembl:ENST00000356455(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1I7K|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5KHR|rcsb pdb:5L9U|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001268670.1|refseq:NP_001268671.1|dip:DIP-52725N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 18.75"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:sJ/R8NL1aVdljasuqKJbVg8gyTM9606 rigid:DCPgs200vCqQ9UikgD8+3HDVHu4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O43166 intact:EBI-7463272|intact:MINT-154028 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501961|imex:IM-28562-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 8.84"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:VRTfPQEVkJzfQN3VJgZdCXmJ+rE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P27635 intact:EBI-7463272|intact:MINT-154028 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501740|imex:IM-28562-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.38"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 rigid:lGkAZ3B+d53gLxEVczwDFzFe/S8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:O14773 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501939|imex:IM-28562-1243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 8.27"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:3P5XCzZKpDc/Mcxikl1dLOTAugU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q14160 intact:EBI-7463272|intact:MINT-154028 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501928|imex:IM-28562-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 7.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:PYfk6VhloGnnNBhHrQKL/P3wrlY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9Y244 intact:EBI-7463272|intact:MINT-154028 intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501917|imex:IM-28562-743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 7.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606 rigid:wKhWIrInrqWRLi5TBVYC+A9rEVU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P38936 intact:EBI-7463272|intact:MINT-154028 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501906|imex:IM-28562-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.96"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:jyU8+6zv6Gg7jNZ1rUuvU64CM9E false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9BYM8 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501895|imex:IM-28562-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.59"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 rigid:+qfss4LIvNCSPGsiQZ3fKueGYY8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9BY21 intact:EBI-7463272|intact:MINT-154028 intact:EBI-11793389|uniprotkb:Q5KU35|uniprotkb:Q96JZ8|uniprotkb:Q9BXC2|ensembl:ENSP00000260843 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:gpr87_human(display_long)|uniprotkb:GPR87(gene name)|psi-mi:GPR87(display_short)|uniprotkb:GPR95(gene name synonym)|uniprotkb:FKSG78(orf name)|uniprotkb:G-protein coupled receptor 95(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501884|imex:IM-28562-1105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_076404.3|ensembl:ENSG00000138271(gene)|ensembl:ENST00000260843(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045028"(G protein-coupled purinergic nucleotide receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR008109(P2Y13 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:e7bygyWUKXkHdEjWW/CKcEIwkdg9606 rigid:yNvgTBphFYCYhebV0VI2lOlyW10 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P52292 intact:EBI-7463272|intact:MINT-154028 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501873|imex:IM-28562-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:HFLxZwHtz5v6egVbyvSdRGhu3wc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P59190 intact:EBI-7463272|intact:MINT-154028 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501862|imex:IM-28562-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.42"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:95iUrDpHlkFUdaHt0o8+zvADkgU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q14116 intact:EBI-7463272|intact:MINT-154028 intact:EBI-3910835|uniprotkb:Q6FGY3|uniprotkb:O75599|intact:EBI-11016725|uniprotkb:Q6WWJ7|ensembl:ENSP00000280357|ensembl:ENSP00000434161 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:il18_human(display_long)|uniprotkb:IL18(gene name)|psi-mi:IL18(display_short)|uniprotkb:IGIF(gene name synonym)|uniprotkb:IL1F4(gene name synonym)|uniprotkb:Iboctadekin(gene name synonym)|uniprotkb:Interferon gamma-inducing factor(gene name synonym)|uniprotkb:Interleukin-1 gamma(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501851|imex:IM-28562-951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:XP_011541107.1|refseq:XP_011541108.1|refseq:NP_001553.1|refseq:NP_001230140.1|ensembl:ENSG00000150782(gene)|ensembl:ENST00000280357(transcript)|ensembl:ENST00000528832(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001525"(angiogenesis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030431"(sleep)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0034105"(positive regulation of tissue remodeling)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045515"(interleukin-18 receptor binding)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051142"(positive regulation of NK T cell proliferation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0150078"(positive regulation of neuroinflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|interpro:IPR000975(Interleukin-1)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR015529(Interleukin 18)|rcsb pdb:1J0S|rcsb pdb:2VXT|rcsb pdb:3F62|rcsb pdb:3WO2|rcsb pdb:3WO3|rcsb pdb:3WO4|rcsb pdb:4EEE|rcsb pdb:4EKX|rcsb pdb:4HJJ|rcsb pdb:4R6U|rcsb pdb:4XFS|rcsb pdb:4XFT|rcsb pdb:4XFU|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-9012546|reactome:R-HSA-9660826|dip:DIP-3785N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:EVCxJD7iNTtAvALzE8GSjbFMWik9606 rigid:PXtOf+VeGoyQszG9+fgmgwC1eLQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P20618 intact:EBI-7463272|intact:MINT-154028 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501840|imex:IM-28562-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.87"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:FOo8zt0yaFsnkCNAuX1WRgAAfd0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P38398 intact:EBI-7463272|intact:MINT-154028 intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501829|imex:IM-28562-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 5.72"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606 rigid:PVp7vSWt/JL7spmRIH43aGCfzQk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9Y2S7 intact:EBI-7463272|intact:MINT-154028 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501818|imex:IM-28562-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.64"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:zsfp4wVxR88N4PSRt+w2v6m+c54 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9Y3C4 intact:EBI-7463272|intact:MINT-154028 intact:EBI-750123|uniprotkb:D6W5H6|uniprotkb:Q8IWR6|uniprotkb:Q8IWR7|uniprotkb:Q9H3K4|ensembl:ENSP00000272424 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tprkb_human(display_long)|uniprotkb:PRPK-binding protein(gene name synonym)|uniprotkb:TPRKB(gene name)|psi-mi:TPRKB(display_short)|uniprotkb:TP53RK-binding protein(gene name synonym)|uniprotkb:CGI-121(orf name)|uniprotkb:My019(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501807|imex:IM-28562-1103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:XP_011531179.1|refseq:XP_011531180.1|refseq:NP_057142.1|refseq:XP_006712090.1|refseq:NP_001317315.1|refseq:NP_001317316.1|refseq:NP_001317317.1|refseq:NP_001317318.1|refseq:NP_001317320.1|refseq:NP_001317321.1|refseq:XP_016859721.1|refseq:XP_016859722.1|refseq:XP_016859723.1|ensembl:ENSG00000144034(gene)|ensembl:ENST00000272424(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR013926(Kinase binding protein CGI-121)|interpro:IPR036504|rcsb pdb:3ENP|rcsb pdb:6WQX|reactome:R-HSA-6782315 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:hsboCuMYBT3FzLom262TDGm5lOQ9606 rigid:sSKQK2q7uWsaGpr3gv9h2aK0hI0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q8TBR4 intact:EBI-7463272|intact:MINT-154028 intact:EBI-26501784|uniprotkb:Q9H8W0 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:st3l4_human(display_long)|uniprotkb:STAG3L4(gene name)|psi-mi:STAG3L4(display_short)|uniprotkb:Stromal antigen 3-like protein 4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501796|imex:IM-28562-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR039662|interpro:IPR013721(STAG) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.89"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:mAdX1m2d/PgRYnATtxKzxtNqd+E9606 rigid:vzlYxTM4yMkFvw9Nop30u+GqLcc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q14188 intact:EBI-7463272|intact:MINT-154028 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501773|imex:IM-28562-949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:Sm6adQhsvnF65DFAhCCmKOAIJbU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q9BVX2 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2821497|uniprotkb:Q3B761|uniprotkb:B2R998|uniprotkb:B7Z5M4|ensembl:ENSP00000400471|ensembl:ENSP00000446657 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:t106c_human(display_long)|uniprotkb:TMEM106C(gene name)|psi-mi:TMEM106C(display_short)|uniprotkb:EMOC(gene name synonym)|uniprotkb:Endoplasmic reticulum membrane protein overexpressed in cancer(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501762|imex:IM-28562-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001137313.1|refseq:NP_001137314.1|refseq:NP_001137315.1|refseq:NP_076961.1|ensembl:ENSG00000134291(gene)|ensembl:ENST00000429772(transcript)|ensembl:ENST00000552561(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009790(Protein of unknown function DUF1356) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.87"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Jh3A/cCsKw8v/V7iZLBejXJ0hTU9606 rigid:H/hbAKDIn2hFNmMqZFa+XgTsqeo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P13693 intact:EBI-7463272|intact:MINT-154028 intact:EBI-1783169|uniprotkb:Q6YLS2|uniprotkb:Q7Z4J4|uniprotkb:Q96EE2|uniprotkb:Q9UC70|intact:EBI-1058458|uniprotkb:B2R7E5|intact:EBI-5772926|uniprotkb:Q8TBK7|ensembl:ENSP00000431872 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tctp_human(display_long)|uniprotkb:TPT1(gene name)|psi-mi:TPT1(display_short)|uniprotkb:p23(gene name synonym)|uniprotkb:Histamine-releasing factor(gene name synonym)|uniprotkb:Fortilin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501751|imex:IM-28562-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_003286.1|refseq:NP_001273202.1|dip:DIP-40097N|ensembl:ENSG00000133112(gene)|ensembl:ENST00000530705(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009615"(response to virus)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|mint:P13693|rcsb pdb:1YZ1|rcsb pdb:2HR9|rcsb pdb:3EBM|rcsb pdb:4Z9V|rcsb pdb:5O9L|rcsb pdb:5O9M|rcsb pdb:6IZB|rcsb pdb:6IZE - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.46"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:1RijAyNqyKFL9LvKa9wbYtC4fRo9606 rigid:SDyVCWxa5X7yeH/3yTYvpG5jk7Q false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q8IYJ3 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501950|imex:IM-28562-1107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 8.82"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:LkQcDI2AB/b2wtr2HsVBfGm5P84 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q05086 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502104|imex:IM-28562-1003 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 494.00"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:/O26ANMbqBTQ5xjAdTuRfx9mkjg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:O14896 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502093|imex:IM-28562-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 4.84"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:VkWB+DhvH8F/E8f93Appw5w2c9s false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q14188 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502082|imex:IM-28562-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.76"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:RjTmD7waFFb57gSHOiOv/STBwfg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q15582 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-10236573|uniprotkb:D3DQB1|uniprotkb:O43218|uniprotkb:O43217|uniprotkb:O14476|uniprotkb:O14472|uniprotkb:O43216|uniprotkb:O43219|uniprotkb:Q53XM1|uniprotkb:O14471|ensembl:ENSP00000416330 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:bgh3_human(display_long)|uniprotkb:TGFBI(gene name)|psi-mi:TGFBI(display_short)|uniprotkb:BIGH3(gene name synonym)|uniprotkb:Kerato-epithelin(gene name synonym)|uniprotkb:RGD-containing collagen-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502071|imex:IM-28562-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000349.1|interpro:IPR032954|interpro:IPR036378|rcsb pdb:1X3B|rcsb pdb:2LTB|rcsb pdb:2LTC|rcsb pdb:2VXP|rcsb pdb:5NV6|rcsb pdb:7AS7|rcsb pdb:7ASC|rcsb pdb:7ASG|reactome:R-HSA-977225|ensembl:ENSG00000120708(gene)|ensembl:ENST00000442011(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR011489(EMI)|interpro:IPR016666(TGF beta-induced protein bIGH3/osteoblast-specific factor 2) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.33"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:86Kh2QpWO6GxkrQsjbtqcBrKs4M9606 rigid:BVyJylAbESEgC4U/QTMtCzyXKDI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:P20618 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502060|imex:IM-28562-1001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:F4rjqhzwMgQJnz+4FmLyBfjZ0XI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q92905 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502049|imex:IM-28562-981 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 rigid:u+eqUPmuJTIr+8WdZqr0v3WM/sI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P55327 intact:EBI-7463272|intact:MINT-154028 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501972|imex:IM-28562-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 9.04"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:ODRxF83eCsI1wGm2Z6xF5KvjA4Q false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q14088 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502027|imex:IM-28562-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:E97stXWvkGPUamSzsiejNoY4S789606 rigid:S21nCArHivT1Kevai924u9mATwI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P14635 uniprotkb:P06929 intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442 intact:EBI-7463272|intact:MINT-154028 psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym) psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502016|imex:IM-28562-803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276 interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 - - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA figure legend:ST6|comment:"Normalized luminescence ratios: 9.89"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rigid:77y5zucItiS3jcK9x6+1nJMih3o false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P28074 intact:EBI-7463272|intact:MINT-154028 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502005|imex:IM-28562-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 9.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:4W8Tv984WEoXt+V3xlbxL+54KaE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:Q14671 intact:EBI-7463272|intact:MINT-154028 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501983|imex:IM-28562-801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 9.19"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:2nIDJJ9ExUPSOp4lvD2gRoEr6MY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06929 uniprotkb:P22234 intact:EBI-7463272|intact:MINT-154028 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26501994|imex:IM-28562-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 9.32"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:h2ArvURyrKPXUV6pMsJCDm110O4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:O75528 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502038|imex:IM-28562-1161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 3.66"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:92gT9BTKfcv6EdLfmTM9J6mBNfw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P84022 intact:EBI-10917424 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502259|imex:IM-28562-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 147.17"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:4Uij4Tjy2IRKpAl7e0r9kULyWKI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:P05549 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502248|imex:IM-28562-1011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 8.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:Qgr8HLmPhiGgmV8qKtImIT0yJXU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:O95551 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502237|imex:IM-28562-1009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 7.99"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:WYeM5DHsiJvNeH3mZGO68m58NwI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:O14773 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502226|imex:IM-28562-1163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 7.17"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:psrnXwYhAWTQ/NAN0o/w5W5VHxg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:P28074 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502215|imex:IM-28562-821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 7.02"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:cohaF37xQbAhkXzhjFhNvsaa+Ks false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P35250 uniprotkb:P36799 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502160|imex:IM-28562-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 - - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA figure legend:ST6|comment:"Normalized luminescence ratios: 5.31"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rigid:PKHuQI2EL5d2MZLWvtYz/0IMgLk false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q96EK4 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502193|imex:IM-28562-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 5.76"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:tcDKFS3/aG7EMx4Vk6eiTJ0iGR4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q14671 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502182|imex:IM-28562-805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:MAP/psNyyx9VobfuCbo5A3moaGo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q8IYJ3 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502171|imex:IM-28562-1005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.49"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:LLxqTgzUCnvPbNzk9lnUFvkEiqQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:P59190 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502149|imex:IM-28562-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.23"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:zxHjQ/M4vZoDewgTWomfgJyrAXY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36799 uniprotkb:Q9BY21 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-11793389|uniprotkb:Q5KU35|uniprotkb:Q96JZ8|uniprotkb:Q9BXC2|ensembl:ENSP00000260843 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:gpr87_human(display_long)|uniprotkb:GPR87(gene name)|psi-mi:GPR87(display_short)|uniprotkb:GPR95(gene name synonym)|uniprotkb:FKSG78(orf name)|uniprotkb:G-protein coupled receptor 95(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502204|imex:IM-28562-1007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_076404.3|ensembl:ENSG00000138271(gene)|ensembl:ENST00000260843(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045028"(G protein-coupled purinergic nucleotide receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR008109(P2Y13 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.85"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:e7bygyWUKXkHdEjWW/CKcEIwkdg9606 rigid:tOsQzzQwlcqlWCc8pyO4NrPlIxY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q8IYJ3 intact:EBI-10917424 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502380|imex:IM-28562-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:V+QGr3Yw28TcVtfpl/9mcEQwZvI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P55327 intact:EBI-10917424 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502369|imex:IM-28562-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:xWM1RjD+xo/TsSzcP4GXaHYGavw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P38936 intact:EBI-10917424 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502358|imex:IM-28562-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.82"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:UO/rB2/q84LsJZP8IUeRko916ag false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P52292 intact:EBI-10917424 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502347|imex:IM-28562-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.62"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:n/BCQ2Y6ypPH+ah6nJHGPiYnsE4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:O43166 intact:EBI-10917424 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502281|imex:IM-28562-1013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 27.20"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:DM7tV05lAmWSdP6EFKotALjyQf4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:O75528 intact:EBI-10917424 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502292|imex:IM-28562-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 29.52"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:XzRR1t4ImM41fW2REE4vbMYYxJk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P38398 intact:EBI-10917424 intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502336|imex:IM-28562-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 4.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606 rigid:BV+BtL4QqDWETgMvaNtbr1ci/PQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P59190 intact:EBI-10917424 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502325|imex:IM-28562-823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:LBzC3C9o6Wok4DZqUfcV3HsVFvg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:O14773 intact:EBI-10917424 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502314|imex:IM-28562-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.04"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:y7ag9lzq4Jfp/mfDtwLJurIfvaA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q15796 intact:EBI-10917424 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502303|imex:IM-28562-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 36.59"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:+YVB6IyIhKraLk7js67CsMry92c false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P20618 intact:EBI-10917424 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502270|imex:IM-28562-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 17.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:uMWnotFAxu14jfCHXFKIQ7h0il0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q96EK4 intact:EBI-10917424 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502391|imex:IM-28562-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 5.53"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:ogiuu6tZm5VZBAWbpPtspt4ro80 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q9BY21 intact:EBI-10917424 intact:EBI-11793389|uniprotkb:Q5KU35|uniprotkb:Q96JZ8|uniprotkb:Q9BXC2|ensembl:ENSP00000260843 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:gpr87_human(display_long)|uniprotkb:GPR87(gene name)|psi-mi:GPR87(display_short)|uniprotkb:GPR95(gene name synonym)|uniprotkb:FKSG78(orf name)|uniprotkb:G-protein coupled receptor 95(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502457|imex:IM-28562-1165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_076404.3|ensembl:ENSG00000138271(gene)|ensembl:ENST00000260843(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045028"(G protein-coupled purinergic nucleotide receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR008109(P2Y13 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:e7bygyWUKXkHdEjWW/CKcEIwkdg9606 rigid:ZjUnVcxzVLUygqVNIpiVfa0CFfE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:P28074 intact:EBI-7463243|intact:MINT-154050 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502704|imex:IM-28562-1173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.23"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:a9J10303lyYpzkz72QnaVuhvs7g false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:P20618 intact:EBI-7463243|intact:MINT-154050 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502693|imex:IM-28562-1021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:E4s8E/rraE3RblKXCZv71mUjUMU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:O95551 intact:EBI-7463243|intact:MINT-154050 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502682|imex:IM-28562-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 4.64"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:NvGk9KSXM1inf7CKIH33xrVJAts false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:Q8IYJ3 intact:EBI-7463243|intact:MINT-154050 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502671|imex:IM-28562-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.85"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:SO8Ih1q+UjLc8sig7nVcjey32nE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:Q13158 intact:EBI-7463243|intact:MINT-154050 intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502660|imex:IM-28562-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_003815.1|dip:DIP-286N|ensembl:ENSG00000168040(gene)|ensembl:ENST00000301838(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002020"(protease binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043278"(response to morphine)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0089720"(caspase binding)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097342"(ripoptosome)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2000454"(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 3.73"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606 rigid:R+F+Ax+8O8hfnYCk7S6npAmKm6w false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:Q15796 intact:EBI-7463243|intact:MINT-154050 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502649|imex:IM-28562-825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 24.48"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:+kPPKm3LGjbmt9J25QZ9YM35ymE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:P84022 intact:EBI-7463243|intact:MINT-154050 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502638|imex:IM-28562-1019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 214.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:Ps/TQ/NUOIlztHToOKvWsz+MlS0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:O43166 intact:EBI-7463243|intact:MINT-154050 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502627|imex:IM-28562-1171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 19.01"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:JErmBn1DTXArW+QkFobo7xPwGgc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:O75528 intact:EBI-7463243|intact:MINT-154050 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502616|imex:IM-28562-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 15.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:+NvTNhForZZle6jFI5fLXhoP9BA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:P38936 intact:EBI-7463243|intact:MINT-154050 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502605|imex:IM-28562-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 10.11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:5CHShcW9Gspu+yIsac9vBWnQDLE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:O95551 intact:EBI-26502480 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502594|imex:IM-28562-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:+6G54owyNJbabHCyAv4JwIygPfs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:Q14671 intact:EBI-26502480 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502583|imex:IM-28562-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.68"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:plJ0QxdEJyE5/7iXBJlgzTGxpe0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:Q8IYJ3 intact:EBI-26502480 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502572|imex:IM-28562-1169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:X3rpIvSflJren7RjH3V+vVTnIVs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:Q14188 intact:EBI-26502480 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502561|imex:IM-28562-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.28"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:Z/surmZGMwGTbNTR/8jsFUbunzA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:O14773 intact:EBI-26502480 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502550|imex:IM-28562-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:MBeVav6tNw/oPe6SYSWLctE7TZs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:Q05086 intact:EBI-26502480 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502539|imex:IM-28562-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 405.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:iP0qotyqju9htESgGbw6oDcBaKY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:P28074 intact:EBI-26502480 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502528|imex:IM-28562-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.81"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:Hnxi0tLnbeoQovvmvQs+vgqKCHo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:P52292 intact:EBI-26502480 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502517|imex:IM-28562-1167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.08"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:ahGcNnSjWORGHqc9d0LtEPl5nTg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:O75528 intact:EBI-26502480 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502506|imex:IM-28562-1017 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 3.89"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:OKvoiuepQ3jkPhH5iZ4490MpXY0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84291 uniprotkb:P38936 intact:EBI-26502480 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502495|imex:IM-28562-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.72"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:Rg3s7ZXGvaTHd+cez2YywlV/dFI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P05549 intact:EBI-10917424 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502468|imex:IM-28562-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 8.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:HbAY4+YF5EgT5Z/h8YaIgUJxq2U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q9BVX2 intact:EBI-10917424 intact:EBI-2821497|uniprotkb:Q3B761|uniprotkb:B2R998|uniprotkb:B7Z5M4|ensembl:ENSP00000400471|ensembl:ENSP00000446657 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:t106c_human(display_long)|uniprotkb:TMEM106C(gene name)|psi-mi:TMEM106C(display_short)|uniprotkb:EMOC(gene name synonym)|uniprotkb:Endoplasmic reticulum membrane protein overexpressed in cancer(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502446|imex:IM-28562-1015 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001137313.1|refseq:NP_001137314.1|refseq:NP_001137315.1|refseq:NP_076961.1|ensembl:ENSG00000134291(gene)|ensembl:ENST00000429772(transcript)|ensembl:ENST00000552561(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009790(Protein of unknown function DUF1356) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.87"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Jh3A/cCsKw8v/V7iZLBejXJ0hTU9606 rigid:+WBBNsafZMJ9+IjZIO3roVrrpiE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q14188 intact:EBI-10917424 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502435|imex:IM-28562-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.46"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:XVGmn/DZeUybm2Jp1nUzySvI1wI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P28074 intact:EBI-10917424 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502424|imex:IM-28562-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.87"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:/L6OPFr0ifQyqJdqVrR9j/BDsDc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:Q13950 intact:EBI-10917424 intact:EBI-976402|intact:EBI-28971669|ensembl:ENSP00000360493|ensembl:ENSP00000495497|uniprotkb:O14614|uniprotkb:O14615|uniprotkb:O95181 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:runx2_human(display_long)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:RUNX2(gene name)|psi-mi:RUNX2(display_short)|uniprotkb:AML3(gene name synonym)|uniprotkb:CBFA1(gene name synonym)|uniprotkb:OSF2(gene name synonym)|uniprotkb:PEBP2A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502413|imex:IM-28562-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENST00000359524|ensembl:ENSP00000352514|ensembl:ENST00000371432|ensembl:ENSP00000360486|ensembl:ENST00000371436|ensembl:ENSP00000360491|ensembl:ENSP00000360493|ensembl:ENSP00000495497|ensembl:ENSG00000124813(gene)|ensembl:ENST00000371438(transcript)|ensembl:ENST00000647337(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|interpro:IPR027384|mint:Q13950|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0043425"(bHLH transcription factor binding)|rcsb pdb:6VG8|rcsb pdb:6VGD|rcsb pdb:6VGE|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|rcsb pdb:6VGG|reactome:R-HSA-2032785|reactome:R-HSA-8878166|reactome:R-HSA-8939246|reactome:R-HSA-8939902|reactome:R-HSA-8940973|reactome:R-HSA-8941284|reactome:R-HSA-8941326|reactome:R-HSA-8941332|reactome:R-HSA-8941333|refseq:NP_001015051.3|refseq:NP_001019801.3|dip:DIP-36707N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.79"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:aUhn8jpJsl5oS4kMBgUYdpncy6Y9606 rigid:gQWVQ7Ntv1xAnvFrHO2b3kfoXxk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:O95551 intact:EBI-10917424 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502402|imex:IM-28562-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:Bm+/JOxet4A+rHWsfafH2hkcRSw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:Q14671 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502884|imex:IM-28562-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.76"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:/6P3ipCgAY0+tdhboKoB/UOU0f8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P14635 uniprotkb:P36801 intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442 intact:EBI-26502745|uniprotkb:Q81988 psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym) psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502873|imex:IM-28562-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276 go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.66"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rigid:tFRxXxE4kqGyZonS3wtwCcVwmUY false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P35250 uniprotkb:P36801 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 intact:EBI-26502745|uniprotkb:Q81988 psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502862|imex:IM-28562-1175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.65"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rigid:x7HJ7pUJKxU43hczK2vlOr6KRCc false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P38936 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502851|imex:IM-28562-1029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:yNBeSk7tRCdWgVV/7JYkJEMuBdE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:Q14188 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502840|imex:IM-28562-1027 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.38"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:uFcHD6+aYrommFkbrb2JiwEIOZY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P59190 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502829|imex:IM-28562-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.12"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:qqw7fNTrlnGSVqIohte/793hQmU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:P05549 intact:EBI-7463243|intact:MINT-154050 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502723|imex:IM-28562-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 5.23"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:Li0+XUCsLQFrotdt7xbBhhKJVdw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:Q9Y244 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502807|imex:IM-28562-1023 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.61"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606 rigid:K+VeG1anLjhAMceGJpO9sXiogKM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P84022 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502796|imex:IM-28562-829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 20.29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:lLBFj05sKk4NYuVmaSijktGKfPI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P20618 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502785|imex:IM-28562-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 18.86"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:+2tRicaMGsDqFyKCAXTbe/yzkho false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O75528 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502774|imex:IM-28562-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 14.12"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:4Sl9ST+2XU+sjVr/qUWL1dFfbLA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P05549 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502763|imex:IM-28562-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 10.93"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:qoMDUOG+p/EtU83zip7S8z+dDcE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06428 uniprotkb:O00762 intact:EBI-7463243|intact:MINT-154050 intact:EBI-719691|uniprotkb:A6NP33|uniprotkb:E1P5N7|uniprotkb:G3XAB7|ensembl:ENSP00000348838 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube2c_human(display_long)|uniprotkb:Ubiquitin-protein ligase C(gene name synonym)|uniprotkb:Ubiquitin carrier protein C(gene name synonym)|uniprotkb:UbcH10(gene name synonym)|uniprotkb:UBE2C(gene name)|psi-mi:UBE2C(display_short)|uniprotkb:UBCH10(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme C"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme C(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502734|imex:IM-28562-827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_008950.1|refseq:NP_861515.1|refseq:NP_861516.1|refseq:NP_861517.1|ensembl:ENSG00000175063(gene)|ensembl:ENST00000356455(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1I7K|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5KHR|rcsb pdb:5L9U|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001268670.1|refseq:NP_001268671.1|dip:DIP-52725N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST6|comment:"Normalized luminescence ratios: 6.59"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:sJ/R8NL1aVdljasuqKJbVg8gyTM9606 rigid:6HGwcuosBB0s7NnFjwjvEMQnvew false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O00303 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502818|imex:IM-28562-1025 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.06"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 rigid:dJQVOim8o9hK38pSOG9eQd0h7qQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q96QZ7 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503280|imex:IM-28562-1039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 93.78"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606 rigid:Wk8ii7TL0J+Too2//x6hsK6yeAg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P27635 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502895|imex:IM-28562-1177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.87"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 rigid:2X6kM4auAaAXzMw/ypsVQRuutP4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q9UBE0 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503258|imex:IM-28562-847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 8.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606 rigid:xrHOFWkaqXssS0j7p14ck/fzqds false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q14160 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503247|imex:IM-28562-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 7.67"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:BGdQ++N6rzyWkDLEO6ldpEpCv/w false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q14188 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503236|imex:IM-28562-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.52"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:TYgv9F7Bcl4P3oLoKOKVrkVNmak false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q14671 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503225|imex:IM-28562-845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:cTl/Ee3DPPWlyv6DAQTN7FR+gVQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P52292 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503214|imex:IM-28562-843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:Kvsb4ELSP+VaK1eL3dgQqxIewMU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P38936 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503203|imex:IM-28562-1037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:Xtch3eZDJMa13FJUDQPIBUeQ3HA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q96EK4 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503192|imex:IM-28562-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 5.92"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:ef/YNhYdSif23Zyex9VvypBmbwM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q15022 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503181|imex:IM-28562-841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:Ou/iOB2mBWMSxux8fln5GURNSGo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P59190 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503170|imex:IM-28562-839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:amnCil6Dcs+SRvbCUlmoej111bM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q8IYJ3 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503159|imex:IM-28562-837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.31"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:ll8BOlF4KVNIvrGVsFLaXmMnFoU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P18848 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503148|imex:IM-28562-835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:ST6|comment:"Normalized luminescence ratios: 5.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:GLfktYm7Jf8YJ74BgnU49K1q8Qo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q9Y244 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503137|imex:IM-28562-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.95"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606 rigid:14Sxhw3svf8q/66VghCCFSh+P6A false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P27635 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503126|imex:IM-28562-1035 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.76"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 rigid:OQ0x5MOhTHz6ucVJMNUybnWe5QE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q9Y2S7 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503115|imex:IM-28562-1033 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.62"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:622LI8155FM6IfeGD2BwJd5ULcU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:O95905 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503104|imex:IM-28562-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606 rigid:lGPvp0ap/AXeQvOvIX5LY7mvWUo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:O43166 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503093|imex:IM-28562-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 4.12"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:idqtYxh+0ya/x+gtxHKgppzJghc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:O14896 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503082|imex:IM-28562-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 387.59"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:3Uhesrk/Lmk9Q9GJXgyOzbXldqI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:O75528 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503071|imex:IM-28562-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 27.99"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:2htAe1PHV4PcgA4UTFCWbMPt+eU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q05086 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503060|imex:IM-28562-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 268.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:XSMyWI3xJh3RytGe+QcoKkfGxh0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P05549 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503049|imex:IM-28562-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 15.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:2xnPC/F3iADD524vbQx2Cg4AMrc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P28074 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503038|imex:IM-28562-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 15.28"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:KmIcD3D9TZL22w6O8TRGTEYWMNI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:P20618 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503027|imex:IM-28562-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 11.40"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:HGsQLblbCnL5g5c2WJjOjfl8W6Q false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:O95551 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503016|imex:IM-28562-1031 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 11.18"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:q57DvJu9w4bJh7S/cGTqfy3nZwY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:Q15796 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503005|imex:IM-28562-833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 9.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:oxsHnr3tejMp0HYIE2MVkIhm010 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O43166 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502994|imex:IM-28562-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 9.36"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:gw9Hfv/+sSLv8OpNF4QpfHwpzoU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O95551 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502983|imex:IM-28562-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 8.62"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:i475YCDWamfB9sPS9Ic9YNYbNAI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:Q96EK4 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502972|imex:IM-28562-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 8.14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:HQyCmNQ38aMXdVAgEFeLL0jw3hU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O14773 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502961|imex:IM-28562-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.64"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:vQiHBp/vm79DNgPfnejM/VxiydU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P28074 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502950|imex:IM-28562-831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.33"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:KWee+Rcqj3rh1AQ5rIXhVxjnuRU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:P18848 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502939|imex:IM-28562-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:ST6|comment:"Normalized luminescence ratios: 6.24"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:q6g+bkz8OoXPs02QuUEg1QDRPBI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O00762 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-719691|uniprotkb:A6NP33|uniprotkb:E1P5N7|uniprotkb:G3XAB7|ensembl:ENSP00000348838 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube2c_human(display_long)|uniprotkb:Ubiquitin-protein ligase C(gene name synonym)|uniprotkb:Ubiquitin carrier protein C(gene name synonym)|uniprotkb:UbcH10(gene name synonym)|uniprotkb:UBE2C(gene name)|psi-mi:UBE2C(display_short)|uniprotkb:UBCH10(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme C"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme C(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502928|imex:IM-28562-1181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_008950.1|refseq:NP_861515.1|refseq:NP_861516.1|refseq:NP_861517.1|ensembl:ENSG00000175063(gene)|ensembl:ENST00000356455(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1I7K|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5KHR|rcsb pdb:5L9U|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001268670.1|refseq:NP_001268671.1|dip:DIP-52725N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:sJ/R8NL1aVdljasuqKJbVg8gyTM9606 rigid:6gE1etNNbW6P93zEDxoUYDt1MxA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:Q8IYJ3 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502917|imex:IM-28562-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.12"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:4uuDkhGY1qilxJp36L+UWm785S0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36801 uniprotkb:O14896 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26502906|imex:IM-28562-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 5.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:fBZP+89Ioy8ZEOw643iXfUm3LFY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03126 uniprotkb:Q13485 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503269|imex:IM-28562-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 8.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:mPu190hmySGV54KAtldys/IHuo89606 rigid:SBp7Y7pPjYSswQoxCSEGSsBAV2M false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q14160 intact:EBI-1186926 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503395|imex:IM-28562-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 3.69"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:PPcc2FqTPzseSIkt0AcA3OUD5Gg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q96F44 intact:EBI-1186926 intact:EBI-851809|uniprotkb:B2RB82|uniprotkb:B3KUS3|uniprotkb:B4DX88|uniprotkb:Q8NCA6|uniprotkb:Q9C022|uniprotkb:A6NKE2|uniprotkb:Q5VSU1|ensembl:ENSP00000284551 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tri11_human(display_long)|uniprotkb:RING finger protein 92(gene name synonym)|uniprotkb:Protein BIA1(gene name synonym)|uniprotkb:TRIM11(gene name)|psi-mi:TRIM11(display_short)|uniprotkb:RNF92(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM11(gene name synonym)|uniprotkb:Tripartite motif-containing protein 11(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503384|imex:IM-28562-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_660215.1|refseq:XP_016857901.1|ensembl:ENSG00000154370(gene)|ensembl:ENST00000284551(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|mint:Q96F44|reactome:R-HSA-983168 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.68"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:cE4Lcnp0zSSEpo3e9Kr940Vdit89606 rigid:f4yL5F+lih4EL4yqsVNPdgn14Qg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9UBE0 intact:EBI-1186926 intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503373|imex:IM-28562-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 21.73"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606 rigid:mgANi9/WUzotOjMeUxXgzyLuYWI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9Y2S7 intact:EBI-1186926 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503362|imex:IM-28562-853 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 18.65"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:UHn10qPNRJQsmJLODdpp7hD3E14 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q14671 intact:EBI-1186926 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503296|imex:IM-28562-849 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 10.66"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:nAG+orsg6RmlCpI1Wfl8nuqzaWE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q05086 intact:EBI-1186926 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503340|imex:IM-28562-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 158.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:qFofmRJgNRcnUkMlEOvDWpC8caM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:O14773 intact:EBI-1186926 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503329|imex:IM-28562-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 14.17"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:XXRtbxIcL30uNaMyZ531PaOLlQw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:O95551 intact:EBI-1186926 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503318|imex:IM-28562-851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 11.74"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:rRwrBa7A9aZ8WIgpxoGXB3AcKFw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P55327 intact:EBI-1186926 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503307|imex:IM-28562-1041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 11.13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:C4tIY7VrNFwU2+BIC9R6qTO71Is false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P07339 intact:EBI-1186926 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503351|imex:IM-28562-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 17.82"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rigid:CJwrcviO40/p+RicgGTh03u6dp8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9BY21 intact:EBI-1186926 intact:EBI-11793389|uniprotkb:Q5KU35|uniprotkb:Q96JZ8|uniprotkb:Q9BXC2|ensembl:ENSP00000260843 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:gpr87_human(display_long)|uniprotkb:GPR87(gene name)|psi-mi:GPR87(display_short)|uniprotkb:GPR95(gene name synonym)|uniprotkb:FKSG78(orf name)|uniprotkb:G-protein coupled receptor 95(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503461|imex:IM-28562-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_076404.3|ensembl:ENSG00000138271(gene)|ensembl:ENST00000260843(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045028"(G protein-coupled purinergic nucleotide receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR008109(P2Y13 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:e7bygyWUKXkHdEjWW/CKcEIwkdg9606 rigid:vuBxoydcEQKa6z1Tfv9FyL9l/No false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P36507 intact:EBI-1186926 intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503472|imex:IM-28562-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.75"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606 rigid:JBxnjo9SGN3TbNu0+saKDszHA40 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P35250 uniprotkb:P06463 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 intact:EBI-1186926 psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503439|imex:IM-28562-1185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rigid:Gu2cxVl/LdrdxeCBWEhdmt+oMi4 false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:O14896 intact:EBI-1186926 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503428|imex:IM-28562-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 4.29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:GwBbmtxmt1widhcfVaaCheLLFrk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:O00303 intact:EBI-1186926 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503417|imex:IM-28562-1183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.28"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 rigid:jfBXOb3KufgD6V0sAIey6i5wdqo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q13485 intact:EBI-1186926 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503406|imex:IM-28562-855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.87"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:mPu190hmySGV54KAtldys/IHuo89606 rigid:SHLK2rq05giI1pwqwCF5cTti13U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q9Y2S7 intact:EBI-11737184 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503818|imex:IM-28562-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:IEmw9CdK+QONaEnDo0XhDEIZArY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P52292 intact:EBI-11737184 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503807|imex:IM-28562-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.74"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:9n6owOYh/tkderbXgV6h4cULCoI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:O14896 intact:EBI-11737184 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503796|imex:IM-28562-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 22.15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:AkCocAPfAegt7Vw0Mw5xW2/fldY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q14160 intact:EBI-11737184 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503785|imex:IM-28562-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 17.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:WPPL7w+szdqgnfIJM7xIQ2CyVd4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q05086 intact:EBI-11737184 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503774|imex:IM-28562-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 142.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:fEnSQRqik8ha/hQY2mdwSpWKYLg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:O95905 intact:EBI-26503648 intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503763|imex:IM-28562-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 90.95"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606 rigid:SCINrflj1J311B7ADWTYGVPZoDQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:Q05086 intact:EBI-26503648 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503752|imex:IM-28562-1047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 882.38"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:SD8GdWdx4CoE+CXuy9Vh7HvR+Qs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:O75528 intact:EBI-26503648 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503741|imex:IM-28562-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 8.67"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:FkFNzJX/IugfqnucfJfDxXXkfI8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:P50995 intact:EBI-26503648 intact:EBI-715243|ensembl:ENSP00000361305|ensembl:ENSP00000398610|ensembl:ENSP00000404412|uniprotkb:B4DVE7|intact:EBI-10981770 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:anx11_human(display_long)|uniprotkb:Annexin-11(gene name synonym)|uniprotkb:Annexin XI(gene name synonym)|uniprotkb:Calcyclin-associated annexin 50(gene name synonym)|uniprotkb:56 kDa autoantigen(gene name synonym)|uniprotkb:ANXA11(gene name)|psi-mi:ANXA11(display_short)|uniprotkb:ANX11(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503730|imex:IM-28562-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000122359(gene)|ensembl:ENST00000372231(transcript)|ensembl:ENST00000422982(transcript)|ensembl:ENST00000438331(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030496"(midbody)|go:"GO:0032506"(cytokinetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR008157(Annexin, type XI, N-terminal)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|refseq:NP_001148.1|refseq:NP_665875.1|refseq:NP_665876.1|refseq:XP_011538038.1|refseq:NP_001265336.1|refseq:NP_001265337.1|refseq:NP_001265338.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.17"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:6j7B4/J0DI0LZADQ5klJQoYf7289606 rigid:Rs9r8t0NaozNtcp7phYNgPsNkvg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:Q14671 intact:EBI-26503648 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503719|imex:IM-28562-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:YmE2ZvmNpJ3ROmJcbOZoEJt+ahc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:O14773 intact:EBI-26503648 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503708|imex:IM-28562-861 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.66"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:Se9BNPRXWqBbM4SurVqd14gHFH8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:Q8IYJ3 intact:EBI-26503648 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503697|imex:IM-28562-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:cxDI05cXW+5fZYS9f9lN8R81zas false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:O95551 intact:EBI-26503648 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503686|imex:IM-28562-1189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.67"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:P9uh4q/wn7tJq7U++AtA5PudP0g false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:Q96EK4 intact:EBI-26503648 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503675|imex:IM-28562-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 3.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:9m71UPEhJZvUV2XuuEU5w7t95g4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36810 uniprotkb:O14896 intact:EBI-26503648 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503664|imex:IM-28562-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 10.06"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:szdyFseYknj5HqnIFdFLCF24d4w false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q13158 intact:EBI-1186926 intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503637|imex:IM-28562-1187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_003815.1|dip:DIP-286N|ensembl:ENSG00000168040(gene)|ensembl:ENST00000301838(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002020"(protease binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043278"(response to morphine)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0089720"(caspase binding)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097342"(ripoptosome)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2000454"(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 9.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606 rigid:szJA9G/0sWbjUZCQOFKiIdgi438 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P05549 intact:EBI-1186926 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503626|imex:IM-28562-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 9.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:GorbTqbDzIQUOocnLBIx8B87tMA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P59190 intact:EBI-1186926 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503615|imex:IM-28562-1045 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 9.39"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:QgUiK7O54hCCTV1qqoo//DxyZUE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P38936 intact:EBI-1186926 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503604|imex:IM-28562-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.95"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:GJUvPDeyu3/AdDZhbcwY5msp75M false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P28074 intact:EBI-1186926 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503593|imex:IM-28562-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.53"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:4HTQN9AKE18j4vaCAAF0z0XFXD8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q96EK4 intact:EBI-1186926 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503582|imex:IM-28562-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 7.11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:80vdRPDPq2SUOoVkCiuNz9QM8HI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q96QZ7 intact:EBI-1186926 intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503571|imex:IM-28562-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 64.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606 rigid:49ertWJ9u+HaT6KT2wiZPg2UA+4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9Y3C4 intact:EBI-1186926 intact:EBI-750123|uniprotkb:D6W5H6|uniprotkb:Q8IWR6|uniprotkb:Q8IWR7|uniprotkb:Q9H3K4|ensembl:ENSP00000272424 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tprkb_human(display_long)|uniprotkb:PRPK-binding protein(gene name synonym)|uniprotkb:TPRKB(gene name)|psi-mi:TPRKB(display_short)|uniprotkb:TP53RK-binding protein(gene name synonym)|uniprotkb:CGI-121(orf name)|uniprotkb:My019(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503560|imex:IM-28562-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:XP_011531179.1|refseq:XP_011531180.1|refseq:NP_057142.1|refseq:XP_006712090.1|refseq:NP_001317315.1|refseq:NP_001317316.1|refseq:NP_001317317.1|refseq:NP_001317318.1|refseq:NP_001317320.1|refseq:NP_001317321.1|refseq:XP_016859721.1|refseq:XP_016859722.1|refseq:XP_016859723.1|ensembl:ENSG00000144034(gene)|ensembl:ENST00000272424(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR013926(Kinase binding protein CGI-121)|interpro:IPR036504|rcsb pdb:3ENP|rcsb pdb:6WQX|reactome:R-HSA-6782315 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.81"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:hsboCuMYBT3FzLom262TDGm5lOQ9606 rigid:vBRVT3RnRhxEbGtFSR1M06Howp0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9Y3D0 intact:EBI-1186926 intact:EBI-744045|ensembl:ENSP00000387471 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503549|imex:IM-28562-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.66"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606 rigid:ggXykhHNPwDiR8oAjJxNQZjf0hQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P32942 intact:EBI-1186926 intact:EBI-725421|uniprotkb:Q6PD68|ensembl:ENSP00000160262 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:icam3_human(display_long)|uniprotkb:ICAM-R(gene name synonym)|uniprotkb:CDw50(gene name synonym)|uniprotkb:ICAM3(gene name)|psi-mi:ICAM3(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503538|imex:IM-28562-1043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_002153.2|ensembl:ENST00000160262(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1T0P|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-5621575|ensembl:ENSG00000076662(gene) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:8A5P9CHbmUsJmlUUbJACHW9Dg9k9606 rigid:wt2ezk7/M5DZISuZdQfTgZ126Ls false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P20618 intact:EBI-1186926 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503527|imex:IM-28562-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.72"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:Euh71U25oEKJ1w1exBq40RKnLRI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9Y244 intact:EBI-1186926 intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503516|imex:IM-28562-859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.50"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606 rigid:EegUTAlRN9W1iq7/rdXaMlrDdIA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q9NYY3 intact:EBI-1186926 intact:EBI-721354|uniprotkb:O60679|uniprotkb:Q96CV7|uniprotkb:Q9UE61|ensembl:ENSP00000274289 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:plk2_human(display_long)|uniprotkb:Polo-like kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNK(gene name synonym)|uniprotkb:Serum-inducible kinase(gene name synonym)|uniprotkb:PLK2(gene name)|psi-mi:PLK2(display_short)|uniprotkb:SNK(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503505|imex:IM-28562-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N dip:DIP-48943N|refseq:NP_006613.2|refseq:NP_001239155.1|ensembl:ENSG00000145632(gene)|ensembl:ENST00000274289(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007613"(memory)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|interpro:IPR042825|rcsb pdb:4I5M|rcsb pdb:4I5P|rcsb pdb:4I6B|rcsb pdb:4I6F|rcsb pdb:4I6H|rcsb pdb:4RS6|rcsb pdb:4XB0|reactome:R-HSA-6804115|reactome:R-HSA-9662834 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.93"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:pjEqMnSG5E6daeauZylX38gmiS09606 rigid:JITougQMaalK4gSiuJG/uRkL0WA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:Q14088 intact:EBI-1186926 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503494|imex:IM-28562-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.91"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:E97stXWvkGPUamSzsiejNoY4S789606 rigid:kvDH2iTWPhX1DiwgWf/zYDNnDkY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:P38398 intact:EBI-1186926 intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503483|imex:IM-28562-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 4.86"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606 rigid:HQy9E6XkEToFwXMfoDp7rsaMVHc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06463 uniprotkb:O43760 intact:EBI-1186926 intact:EBI-2826419|intact:EBI-4289558|uniprotkb:O43762|uniprotkb:Q3KQZ2|uniprotkb:Q658S7|ensembl:ENSP00000225777|ensembl:ENSP00000465678 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sng2_human(display_long)|uniprotkb:SYNGR2(gene name)|psi-mi:SYNGR2(display_short)|uniprotkb:Cellugyrin(gene name synonym)|uniprotkb:UNQ352/PRO615(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503450|imex:IM-28562-857 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_004701.1|refseq:NP_001307452.1|ensembl:ENSG00000108639(gene)|ensembl:ENST00000225777(transcript)|ensembl:ENST00000585591(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:O43760|refseq:XP_005257849.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:RuUsRvpeTl8Akv3c3s7rt0zuoKU9606 rigid:ID6SQDm/p5Rh7b9itkvnPQL/QxM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q14188 intact:EBI-11737184 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503851|imex:IM-28562-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.89"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:YqHjVkwhUNwcF5Z/oC58aFFXx4w false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q8TBR4 intact:EBI-11737184 intact:EBI-26501784|uniprotkb:Q9H8W0 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:st3l4_human(display_long)|uniprotkb:STAG3L4(gene name)|psi-mi:STAG3L4(display_short)|uniprotkb:Stromal antigen 3-like protein 4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503829|imex:IM-28562-1191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR039662|interpro:IPR013721(STAG) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:mAdX1m2d/PgRYnATtxKzxtNqd+E9606 rigid:5za10EoWHbkeoKsex/iTJtAtWmE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q8IYJ3 intact:EBI-11737184 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503840|imex:IM-28562-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:Jni2QKfVOw9Y5FRl/YUiL3oM+80 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q9BY21 intact:EBI-11793707 intact:EBI-11793389|uniprotkb:Q5KU35|uniprotkb:Q96JZ8|uniprotkb:Q9BXC2|ensembl:ENSP00000260843 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:gpr87_human(display_long)|uniprotkb:GPR87(gene name)|psi-mi:GPR87(display_short)|uniprotkb:GPR95(gene name synonym)|uniprotkb:FKSG78(orf name)|uniprotkb:G-protein coupled receptor 95(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504247|imex:IM-28562-1201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_076404.3|ensembl:ENSG00000138271(gene)|ensembl:ENST00000260843(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045028"(G protein-coupled purinergic nucleotide receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR008109(P2Y13 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:e7bygyWUKXkHdEjWW/CKcEIwkdg9606 rigid:SSLjozzUMigOsTG/rG0vf/HEK08 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P36507 intact:EBI-11793707 intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504236|imex:IM-28562-1051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606 rigid:lUcv0BM5lLQqdZlBwMlTWnHzsOc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q96EK4 intact:EBI-11793707 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504225|imex:IM-28562-1199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 5.79"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:c26MNfkbNa0ULtdaXn38qfjcPzs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P20618 intact:EBI-11793707 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504214|imex:IM-28562-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:Jk1LHmablgJCTBXOSQHN7KkvWSo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P38936 intact:EBI-11793707 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504203|imex:IM-28562-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:0Q5iZa/RA3J679uV0yRU5iB/bV0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q9Y2S7 intact:EBI-11793707 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504192|imex:IM-28562-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.10"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:p/Iznv634X8BZdIgUiRv4mtakE8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q96QZ7 intact:EBI-11793707 intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504181|imex:IM-28562-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 41.55"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606 rigid:Wm+WQoiu2rRpr39q35fLZSL2kK8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P52292 intact:EBI-11793707 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504170|imex:IM-28562-1197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.92"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:vV9GTM4lEGj0rl4rRCknDIQ6LwQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P55327 intact:EBI-11793707 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504159|imex:IM-28562-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:qf7+4+s1pYxpaXbEACb9dHfZwok false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q14188 intact:EBI-11793707 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504148|imex:IM-28562-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.20"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:+6JjKqAItgWhkKVNDAkfIMFgTq8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q8IYJ3 intact:EBI-11793707 intact:EBI-2802861|uniprotkb:Q96SI0|uniprotkb:Q96S89|uniprotkb:Q96GU6|uniprotkb:Q96BB6|uniprotkb:Q5SSC9|ensembl:ENSP00000440704|ensembl:ENSP00000481032 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sytl1_human(display_long)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Exophilin-7(gene name synonym)|uniprotkb:Protein JFC1(gene name synonym)|uniprotkb:SB146(orf name)|uniprotkb:SYTL1(gene name)|psi-mi:SYTL1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504137|imex:IM-28562-869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001180237.1|refseq:NP_116261.1|ensembl:ENSG00000142765(gene)|ensembl:ENST00000616558(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR028378|interpro:IPR035892|interpro:IPR043567|reactome:R-HSA-8854214|ensembl:ENST00000543823(transcript) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.00"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:rvuIk8EvKrbGkp4F+7+8fimZaIQ9606 rigid:j2KYAy1QaGUOnMdcU8nuTca4UKg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P35250 uniprotkb:P24835 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 intact:EBI-11793707 psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504126|imex:IM-28562-867 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rigid:8RTe1GJvIzufPhJ1pqYXEPLYxrw false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q96F44 intact:EBI-11793707 intact:EBI-851809|uniprotkb:B2RB82|uniprotkb:B3KUS3|uniprotkb:B4DX88|uniprotkb:Q8NCA6|uniprotkb:Q9C022|uniprotkb:A6NKE2|uniprotkb:Q5VSU1|ensembl:ENSP00000284551 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tri11_human(display_long)|uniprotkb:RING finger protein 92(gene name synonym)|uniprotkb:Protein BIA1(gene name synonym)|uniprotkb:TRIM11(gene name)|psi-mi:TRIM11(display_short)|uniprotkb:RNF92(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM11(gene name synonym)|uniprotkb:Tripartite motif-containing protein 11(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504115|imex:IM-28562-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_660215.1|refseq:XP_016857901.1|ensembl:ENSG00000154370(gene)|ensembl:ENST00000284551(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|mint:Q96F44|reactome:R-HSA-983168 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:cE4Lcnp0zSSEpo3e9Kr940Vdit89606 rigid:Mb5INY23W6ZxosZBTDFamqY0M+A false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q13158 intact:EBI-11793707 intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504104|imex:IM-28562-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_003815.1|dip:DIP-286N|ensembl:ENSG00000168040(gene)|ensembl:ENST00000301838(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002020"(protease binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043278"(response to morphine)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0089720"(caspase binding)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097342"(ripoptosome)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2000454"(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 3.81"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606 rigid:8/3JCi8L6yfyjCDCd6chsXFLAv0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q9BXK5 intact:EBI-11793707 intact:EBI-747430|uniprotkb:Q96B37|uniprotkb:Q96IB7|uniprotkb:Q9BY01|uniprotkb:Q9HC05|uniprotkb:Q9UFE0|uniprotkb:Q9UKN3|ensembl:ENSP00000318883|uniprotkb:B3KPE7 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:b2l13_human(display_long)|uniprotkb:Protein Mil1(gene name synonym)|uniprotkb:Bcl-rambo(gene name synonym)|uniprotkb:BCL2L13(gene name)|psi-mi:BCL2L13(display_short)|uniprotkb:MIL1(gene name synonym)|uniprotkb:CD003(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504093|imex:IM-28562-1195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_056182.2|refseq:XP_011544423.1|ensembl:ENSG00000099968(gene)|ensembl:ENST00000317582(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR026298|interpro:IPR036834|interpro:IPR042398|rcsb pdb:2IPD|dip:DIP-60895N|refseq:NP_001257658.1|refseq:NP_001257659.1|refseq:NP_001257660.1|refseq:XP_016884217.1|refseq:XP_016884218.1|refseq:XP_016884219.1|refseq:XP_016884220.1|refseq:XP_016884221.1|refseq:XP_016884222.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.69"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:CTVG9Xyunw/XyOeGX4zYaSXdo6Y9606 rigid:dyy2ABaEgx+7QELI4XmmYKXvVFY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q9BQE3 intact:EBI-11793707 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504082|imex:IM-28562-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.68"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 rigid:Sa/GJMr8MatcuOVlBjA0s/c/El4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q9Y3C4 intact:EBI-11793707 intact:EBI-750123|uniprotkb:D6W5H6|uniprotkb:Q8IWR6|uniprotkb:Q8IWR7|uniprotkb:Q9H3K4|ensembl:ENSP00000272424 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tprkb_human(display_long)|uniprotkb:PRPK-binding protein(gene name synonym)|uniprotkb:TPRKB(gene name)|psi-mi:TPRKB(display_short)|uniprotkb:TP53RK-binding protein(gene name synonym)|uniprotkb:CGI-121(orf name)|uniprotkb:My019(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504071|imex:IM-28562-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:XP_011531179.1|refseq:XP_011531180.1|refseq:NP_057142.1|refseq:XP_006712090.1|refseq:NP_001317315.1|refseq:NP_001317316.1|refseq:NP_001317317.1|refseq:NP_001317318.1|refseq:NP_001317320.1|refseq:NP_001317321.1|refseq:XP_016859721.1|refseq:XP_016859722.1|refseq:XP_016859723.1|ensembl:ENSG00000144034(gene)|ensembl:ENST00000272424(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR013926(Kinase binding protein CGI-121)|interpro:IPR036504|rcsb pdb:3ENP|rcsb pdb:6WQX|reactome:R-HSA-6782315 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.57"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:hsboCuMYBT3FzLom262TDGm5lOQ9606 rigid:glBGIsMr0dndbfHbFa5eOq3P9wY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:O95905 intact:EBI-11793707 intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504060|imex:IM-28562-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 3.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606 rigid:hK7OoKJ2VY8XlrR7/JZfmLHzrn0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:O75528 intact:EBI-11793707 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504049|imex:IM-28562-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 29.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:cMf4prHpF3IYl1qenawdwwy2Zp0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q05086 intact:EBI-11793707 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504038|imex:IM-28562-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 190.22"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:IHf/fRoFRindSBC0yzLAf7slUn4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:O14896 intact:EBI-11793707 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504027|imex:IM-28562-1193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 116.93"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:azh7Pxgvo0Shz7jJfdodIeDhFlY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q14088 intact:EBI-11793707 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504016|imex:IM-28562-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 10.46"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:E97stXWvkGPUamSzsiejNoY4S789606 rigid:Z90Gw1PUYRIRnilWWdRggDCOsb8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q14671 intact:EBI-11737184 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504005|imex:IM-28562-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.96"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:fwIbslOVdXDR2REa4A9r+71ufOw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:O43166 intact:EBI-11737184 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503994|imex:IM-28562-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 6.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:oECmIcgkZJO5Ls1z/Vj2IwER07Y false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P28074 intact:EBI-11737184 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503983|imex:IM-28562-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.86"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:JmDoDM6Z6OMWPSH5uNyf1oD3Mxk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:O95551 intact:EBI-11737184 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503972|imex:IM-28562-865 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:jtFlXq3TeqUlpzP3rFKABHlYFvw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:O95905 intact:EBI-11737184 intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503961|imex:IM-28562-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.34"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606 rigid:BXu4hmsmMG2SFYMV6OP6kFPri/U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P05549 intact:EBI-11737184 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503950|imex:IM-28562-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.26"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:h7dKfmmh1ToEIqjaT2DBZJTctmo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q96EK4 intact:EBI-11737184 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503939|imex:IM-28562-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST6|comment:"Normalized luminescence ratios: 6.02"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:wMg5i1+0NGiu/ixXFHPe4KbG1pY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q96QZ7 intact:EBI-11737184 intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503928|imex:IM-28562-1049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 51.71"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606 rigid:pu2py2v0dsUT9QR/CjkoMedPOiQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P55327 intact:EBI-11737184 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503917|imex:IM-28562-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:f+ZhRVUPNCbcwn2R4Hja0HjCRys false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P22234 intact:EBI-11737184 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503906|imex:IM-28562-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 5.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:e/MG2NCvwlrjzglF7NYjTcLXXFU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P59190 intact:EBI-11737184 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503895|imex:IM-28562-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.65"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:DV8zg9iR2/A07/Eqy2oO0gSTaOQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:O75528 intact:EBI-11737184 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503884|imex:IM-28562-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 4.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:k5HoeGloIQbCK2VI+i/qS0jbCag false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:P20618 intact:EBI-11737184 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503873|imex:IM-28562-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.55"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:TmcH+ZLIhruFnl4bIFZ6/78y/co false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06427 uniprotkb:Q12959 intact:EBI-11737184 intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26503862|imex:IM-28562-863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 4.11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606 rigid:TtLeU/orpWbUoBBVBKZz3P2oKVA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q9UBE0 intact:EBI-11793707 intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504291|imex:IM-28562-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.79"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606 rigid:cZrwePZUEyulYoJ1xHRIGFEvI78 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:O95551 intact:EBI-11793707 intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504280|imex:IM-28562-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway) - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.33"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606 rigid:aROcXkexrUnCDZrUgrw7G7t3vpg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P59190 intact:EBI-11793707 intact:EBI-3048571|ensembl:ENSP00000434103|uniprotkb:Q8IW89|uniprotkb:Q86TX7|uniprotkb:G5EMR7 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rab15_human(display_long)|uniprotkb:RAB15(gene name)|psi-mi:RAB15(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504269|imex:IM-28562-871 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000139998(gene)|ensembl:ENST00000533601(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826|reactome:R-HSA-8873719|refseq:NP_001295083.1|refseq:NP_941959.1 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 6.85"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:Bh4JGRoieQZbQGnXCvneLO13kEc9606 rigid:GTBQ5I+An6AA7AhJzt4T3EgDfvY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:Q14160 intact:EBI-11793707 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504258|imex:IM-28562-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:ST6 F4A|comment:"Normalized luminescence ratios: 6.17"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:ldP7sSnSu4GK24P/nRQhwGY/pDY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q15572 intact:EBI-963841 intact:EBI-2510659|ensembl:ENSP00000455265|uniprotkb:Q59F67|uniprotkb:B7Z5K5|uniprotkb:B7Z5S4|uniprotkb:B7Z9L7|uniprotkb:B7Z908|uniprotkb:Q8N6V3 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:taf1c_human(display_long)|uniprotkb:TAF1C(gene name)|psi-mi:TAF1C(display_short)|uniprotkb:Transcription initiation factor SL1/TIF-IB subunit C(gene name synonym)|uniprotkb:TATA box-binding protein-associated factor 1C(gene name synonym)|uniprotkb:RNA polymerase I-specific TBP-associated factor 110 kDa(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504401|imex:IM-28562-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000103168(gene)|ensembl:ENST00000567759(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR038801|mint:Q15572|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|refseq:NP_001230086.1|refseq:NP_001230087.1|refseq:NP_001230088.1|refseq:NP_005670.3|refseq:NP_001230085.1|refseq:NP_647610.2|refseq:XP_005256283.1|refseq:XP_016879334.1|refseq:XP_016879337.1|dip:DIP-269N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 12.19"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:m2f2Ck6oSvfJA8AyIpjSn0Y+k0w9606 rigid:akRbPdWKDtewRNa2xaTdYmMY4ho false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P12004 intact:EBI-963841 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504390|imex:IM-28562-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 12.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:21YHEgik5cIHsNAFABjmxpdEv2U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q14168 intact:EBI-963841 intact:EBI-3046657|uniprotkb:Q53ES9|uniprotkb:Q9BQJ2|uniprotkb:Q5CZB9|uniprotkb:E7EX01|uniprotkb:B4DGE9|uniprotkb:B4DRJ0|uniprotkb:B7Z3G8|uniprotkb:E7EV80|uniprotkb:E7EV91 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mpp2_human(display_long)|uniprotkb:MPP2(gene name)|psi-mi:MPP2(display_short)|uniprotkb:DLG2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Protein MPP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504379|imex:IM-28562-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_005365.4|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:2E7K|refseq:NP_001265305.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|refseq:NP_001265299.1|refseq:NP_001265300.1|refseq:NP_001265301.1|refseq:NP_001265302.1|refseq:NP_001265303.1|refseq:NP_001265304.1|refseq:NP_001265310.1|interpro:IPR035602|mint:Q14168|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 11.95"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:V/6k8hS86wWuXs+iU37my9MOYtc9606 rigid:CCbPv6+7HQ+M2A1FrYPRWg7hDrI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q9UHC7 intact:EBI-963841 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504368|imex:IM-28562-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 11.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:cIYcwyE6i4aakYKU2d9CcbcgVHw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q96PU8 intact:EBI-963841 intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504357|imex:IM-28562-1203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 10.99"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606 rigid:WibEcQATuFhEh9CAgBMNLQIO1Bo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q9Y6Q5 intact:EBI-963841 intact:EBI-752250|uniprotkb:Q9BSI8|uniprotkb:B2RDV5|ensembl:ENSP00000250244 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap1m2_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-2 subunit(gene name synonym)|uniprotkb:Mu-adaptin 2(gene name synonym)|uniprotkb:AP-mu chain family member mu1B(gene name synonym)|uniprotkb:Mu1B-adaptin(gene name synonym)|uniprotkb:AP1M2(gene name)|psi-mi:AP1M2(display_short)|uniprotkb:Adaptor protein complex AP-1 subunit mu-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-2 medium chain 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504346|imex:IM-28562-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_005489.2|refseq:NP_001287816.1|ensembl:ENSG00000129354(gene)|ensembl:ENST00000250244(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 10.92"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:Zb94TVE2hogjzn1QKDV3vWRNsWo9606 rigid:Jlsj5G3xFzRloiTDT+aOmKO5Hs8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P07339 intact:EBI-11793707 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504335|imex:IM-28562-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 9.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rigid:Db5hL9G1n93WW763ENMgr+r7az8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P28074 intact:EBI-11793707 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504324|imex:IM-28562-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:ST6|comment:"Normalized luminescence ratios: 8.57"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:60KpFjAeEVKOo5bamzU9bFZQnsw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:O14773 intact:EBI-11793707 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504313|imex:IM-28562-873 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:ST6|comment:"Normalized luminescence ratios: 8.08"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:PUbsPp+kjCpIwG31Y0LQHwJ0B5A false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24835 uniprotkb:P05549 intact:EBI-11793707 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504302|imex:IM-28562-1053 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST6|comment:"Normalized luminescence ratios: 7.96"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:yMvw5BKGNw4pnkr8A0VKJXcBDJ8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:Q9UBS4 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504899|imex:IM-28562-883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:Pl+6I/Y0supeCdbZRga6lCGTD5U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P16144 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504888|imex:IM-28562-707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.01"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:mc+HAiRSFI/z92h8OYTIP4VbzyY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P39023 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504877|imex:IM-28562-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.42"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:yTY3q2YcMHB+Agfvw21PdysmNYM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P60709 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504866|imex:IM-28562-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rigid:uZioq76wA4RG1tTQI7kozQANhHU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P28749 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504855|imex:IM-28562-881 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.69"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:+JnQUOjlnXDQEUJ5/oeSDUIZXHA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P12004 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504844|imex:IM-28562-1057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:VvTCq8M8su7NXM9qzjEpB7p0swg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P20618 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504833|imex:IM-28562-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.38"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:+bTMoAjt1mIthkvbzhw1GsQmghw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P13667 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504822|imex:IM-28562-1217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.38"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:mNnUPdEvJk8OC6lE4DFneYc/MsE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P14618 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504811|imex:IM-28562-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.16"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:ODBSUQlA6xYgkr2nLTotlCHNe8E false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:Q15005 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504800|imex:IM-28562-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.97"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:s+NGvDpdmm4WYwOylDhhYCnRLBA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P10914 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-1055781|uniprotkb:Q96GG7|ensembl:ENSP00000245414|ensembl:ENSP00000384406 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:irf1_human(display_long)|uniprotkb:IRF1(gene name)|psi-mi:IRF1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504789|imex:IM-28562-1215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_002189.1|ensembl:ENSG00000125347(gene)|ensembl:ENST00000245414(transcript)|ensembl:ENST00000405885(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043374"(CD8-positive, alpha-beta T cell differentiation)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031215|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231|dip:DIP-40988N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.78"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:ToPrN31Dt6/EQuaX8gkxFBDJp5Q9606 rigid:93RNVFRYr+4fDFbrQZBTaDNqD5k false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P38936 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504778|imex:IM-28562-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 3.75"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:V9/cE82/3kQ1p0eOG4NZ0Ss2chg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P29590 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504767|imex:IM-28562-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 13.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:yJzwW5ZI76TRXelh5mGFoAEpeSE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:P50479 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504756|imex:IM-28562-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 12.48"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:yU9wLMYCoh/Nxfqqn0EWPOs3Gp0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q16831 intact:EBI-963841 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504745|imex:IM-28562-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:/lLVphx/4B0dhmQEj4W3yy25OyA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q9UBS4 intact:EBI-963841 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504723|imex:IM-28562-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.00"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:xHUWnuiuTk7/7usf+vZK3F3VVjc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q15005 intact:EBI-963841 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504734|imex:IM-28562-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.26"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:IAIzubuwWboAe/qel7IKr4B4bHw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P39023 intact:EBI-963841 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504712|imex:IM-28562-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.28"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:+xZ+fWUQl4p2gh25cF1PTxOVT90 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P08571 intact:EBI-963841 intact:EBI-3905196|uniprotkb:Q96L99|uniprotkb:Q53XT5|uniprotkb:Q9UNS3|uniprotkb:Q96FR6|ensembl:ENSP00000304236|ensembl:ENSP00000385519 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cd14_human(display_long)|uniprotkb:CD14(gene name)|psi-mi:CD14(display_short)|uniprotkb:Myeloid cell-specific leucine-rich glycoprotein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504701|imex:IM-28562-1213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_000582.1|refseq:NP_001035110.1|refseq:NP_001167575.1|refseq:NP_001167576.1|dip:DIP-1030N|ensembl:ENSG00000170458(gene)|ensembl:ENST00000302014(transcript)|ensembl:ENST00000401743(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001847"(opsonin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016019"(peptidoglycan immune receptor activity)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR016337(Monocyte differentiation antigen CD14)|interpro:IPR032675|rcsb pdb:4GLP|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-975163|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling) - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:MpfQfOF+t0EMlzBio2kyYeJU3hE9606 rigid:UX6UT37fDa1RKsjBVS7pVSeM77c false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P06400 intact:EBI-963841 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504690|imex:IM-28562-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 7.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:wp4jBk2mLHyI2tIVL/PbgOGNvWc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P17936 intact:EBI-963841 intact:EBI-715709|uniprotkb:Q2V509|uniprotkb:Q6P1M6|uniprotkb:A4D2F5|uniprotkb:Q9UCL4|uniprotkb:D3DVM0|ensembl:ENSP00000477772 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ibp3_human(display_long)|uniprotkb:IGFBP3(gene name)|psi-mi:IGFBP3(display_short)|uniprotkb:IBP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504679|imex:IM-28562-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_000589.2|refseq:NP_001013416.1|ensembl:ENSG00000146674(gene)|ensembl:ENST00000613132(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012211(Insulin-like growth factor binding protein 3)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|mint:P17936|reactome:R-HSA-381426|reactome:R-HSA-6803211|reactome:R-HSA-8957275|refseq:XP_016867641.1|dip:DIP-40786N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 7.60"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:zb2NzKqdY6oCXbF/DrT5etyMeEU9606 rigid:c3S9/O2aBY7SEwWBG7jcBeYeihw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q96EK4 intact:EBI-963841 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504668|imex:IM-28562-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST7|comment:"Normalized luminescence ratios: 7.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:eqamfLi85fBHeJR6pA2eKoECRsE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P20618 intact:EBI-963841 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504657|imex:IM-28562-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.64"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:VO5p6fjL8mVrYaUe+gueyG4fzZw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P16144 intact:EBI-963841 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504646|imex:IM-28562-1211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 54.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:aFx/aJ4SKIoe7UVqBLAMi+jHyy0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P05549 intact:EBI-963841 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504635|imex:IM-28562-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.92"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:/T1N6bXvOfTiQZ+EZYYnL7Aza8Q false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q8IZC6 intact:EBI-963841 intact:EBI-2529384|uniprotkb:Q66K43|uniprotkb:Q96JF7|ensembl:ENSP00000348385 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cora1_human(display_long)|uniprotkb:COL27A1(gene name)|psi-mi:COL27A1(display_short)|uniprotkb:KIAA1870(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504624|imex:IM-28562-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000196739(gene)|ensembl:ENST00000356083(transcript)|go:"GO:0003431"(growth plate cartilage chondrocyte development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005583"(fibrillar collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_116277.2 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.86"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:+Hwz0vac4YiN3eiJr0WxgHuQsiM9606 rigid:gzId/kP9CoEs2cS+Tp+AHGKqZ6o false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P25106 intact:EBI-963841 intact:EBI-1965291|uniprotkb:A8K6J4|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938|ensembl:ENSP00000272928 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504613|imex:IM-28562-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:XP_016860005.1|refseq:NP_064707.1|refseq:XP_005246154.1|refseq:XP_005246155.1|ensembl:ENSG00000144476(gene)|ensembl:ENST00000272928(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6K3F|reactome:R-HSA-380108|reactome:R-HSA-418594 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.24"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606 rigid:6cTIjHMLPEjDmGakbumLG0I//XA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P25685 intact:EBI-963841 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504602|imex:IM-28562-879 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.06"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:VKhL8Y4YUTh+M/e4+xWO9V+2XQM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P28749 intact:EBI-963841 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504591|imex:IM-28562-1055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 42.29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:4NySqK09FsQvoUR5vyFmMZW+CnY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P60709 intact:EBI-963841 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504580|imex:IM-28562-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.80"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rigid:pz3hD7U+/jzIA+AboIC4LOGgDYc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P38936 intact:EBI-963841 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504569|imex:IM-28562-877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.40"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:DiGdIRVlo0nCtqE/dvIf8l44OJw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P10914 intact:EBI-963841 intact:EBI-1055781|uniprotkb:Q96GG7|ensembl:ENSP00000245414|ensembl:ENSP00000384406 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:irf1_human(display_long)|uniprotkb:IRF1(gene name)|psi-mi:IRF1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504558|imex:IM-28562-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_002189.1|ensembl:ENSG00000125347(gene)|ensembl:ENST00000245414(transcript)|ensembl:ENST00000405885(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043374"(CD8-positive, alpha-beta T cell differentiation)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031215|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231|dip:DIP-40988N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.30"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:ToPrN31Dt6/EQuaX8gkxFBDJp5Q9606 rigid:ZyMU+h5JcUHhbDPE8ld6MiocKXY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P68104 intact:EBI-963841 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504547|imex:IM-28562-1209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:3xtPXLyzJhQK8TD1VyUiUtDgdYg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P29590 intact:EBI-963841 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504536|imex:IM-28562-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 37.96"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:fDrynD0IJzU/5BsjQjIT+p7fzDw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P04632 intact:EBI-963841 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504525|imex:IM-28562-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 36.53"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:Jri+3YZJk4D9bkmr1iCNufXgJwU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q96EY1 intact:EBI-963841 intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504514|imex:IM-28562-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 3.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606 rigid:TEqA7qyo2G0bGUSipfmV/+pU+iA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:O94842 intact:EBI-963841 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504503|imex:IM-28562-1207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.79"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:Ro4mDjfiuVUtmIh4EtZyjabfsGc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q8N1F7 intact:EBI-963841 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504492|imex:IM-28562-875 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.78"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 rigid:iNsZdl8JqrnQlKRabwxW8F5cvWA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:O15160 intact:EBI-963841 intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504481|imex:IM-28562-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.59"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606 rigid:kae6FKPv6IBR6rFaEn2OxQSI07s false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:O60814 intact:EBI-963841 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504470|imex:IM-28562-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.53"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 rigid:k2AdrsFnJnJsA3KgyTdUZYWFIqg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q13362 intact:EBI-963841 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504459|imex:IM-28562-1205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 rigid:aWNxSEkOaJFOAg95QV0wKlTANBU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P14618 intact:EBI-963841 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504448|imex:IM-28562-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 27.57"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:GxR0eFLsuKW33B5J8A9y0F599Gw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:P50479 intact:EBI-963841 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504437|imex:IM-28562-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 16.38"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:HjG81xjjHFTvKwP/ZbP8awjSNLE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q99729 intact:EBI-963841 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504426|imex:IM-28562-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 16.00"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:FRXWNvi6eGIrDtt+5KzKxtPxSNo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06465 uniprotkb:Q9UNK0 intact:EBI-963841 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504415|imex:IM-28562-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 14.91"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:v5PG579sXRrwA4mcp77Y2SWyQAU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q16831 intact:EBI-26504932 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504968|imex:IM-28562-885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 11.52"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:7/g5+ge9RAGNpI38o7S37iF8sP4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q9UNK0 intact:EBI-26504932 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504957|imex:IM-28562-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 11.17"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:0zC2TQN3HmBr0k8RGMRsBQWy1VU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q9UHC7 intact:EBI-26504932 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504946|imex:IM-28562-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 10.68"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:GD62jpJ+qHrJpkSzUrl9DjTU+Uw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:Q16831 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504921|imex:IM-28562-1059 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:mU/Wz0oIH6rC6qUlIUvN/Gizma0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06932 uniprotkb:Q9UNK0 intact:EBI-11724989|uniprotkb:Q6LBH5|uniprotkb:Q6YNY3|uniprotkb:Q81963|uniprotkb:Q81987 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv05(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26504910|imex:IM-28562-709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041366.1 refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.01"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:OC24vj0+gb1Xkqh9fGFaoFY5ttk333923 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:8koBaNOQbAqnYpUtpITVc2/VkmU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:Q15005 intact:EBI-11722553 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505243|imex:IM-28562-891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.99"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:c8l3fEHByeAChrVf1/nv8bE+Rrw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:P28749 intact:EBI-11722553 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505232|imex:IM-28562-1069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 7.61"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:YTQO4IWsfdAquR00dHUE7nlHhoU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:P20618 intact:EBI-11722553 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505221|imex:IM-28562-1221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.01"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:ndlue0dvO6+ZoH7XTrlIrgUCJaU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:Q9UBS4 intact:EBI-11722553 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505210|imex:IM-28562-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.57"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:3F4apv3lpmfzfpLPrISjCBkv/pM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:Q16831 intact:EBI-11722553 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505199|imex:IM-28562-889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.46"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:X31wmhFzTEfuGxc5bk2fwqMGoWc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:Q9UNK0 intact:EBI-11722553 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505188|imex:IM-28562-1067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.19"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:wwwdkyCZ7SjV6b1XRUPiSnsTOC8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:P12004 intact:EBI-11722553 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505177|imex:IM-28562-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:Ecu6r7pCBqfZpANKJwsnVn1vtVk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:P29590 intact:EBI-11722553 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505166|imex:IM-28562-1219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 12.73"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:ynKKi71EmzVYS3kBUQ7GQTkF2lY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q99729 intact:EBI-26504932 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505155|imex:IM-28562-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.53"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:ia7ShCnbNqTZbY/3p5ji4OOFKc8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P14618 intact:EBI-26504932 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505144|imex:IM-28562-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 7.52"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:5AXngpIGNX3870XPhW/PbNsaNYg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q9UBS4 intact:EBI-26504932 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505133|imex:IM-28562-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.26"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:HLIZSnwJgTT9u+TjIKdD87Mfo9w false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q9UHR5 intact:EBI-26504932 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505122|imex:IM-28562-1065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rigid:7sAbBc/aX0lXF5MSnHeS7sylihM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P12004 intact:EBI-26504932 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505111|imex:IM-28562-1063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:DbsqYeU2ty6CA8Cx9rViwwTxU/A false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P39023 intact:EBI-26504932 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505100|imex:IM-28562-713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.73"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:iDho9X5ZWKUoJzxQYnzMxv6j/BU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q96PU8 intact:EBI-26504932 intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505089|imex:IM-28562-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.25"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606 rigid:i6TYbXmaDGdzt7FHianRNKASPDA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P20618 intact:EBI-26504932 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505078|imex:IM-28562-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.10"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:dGBtTqAxnEAWb8UzDikU86v7zX4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P25106 intact:EBI-26504932 intact:EBI-1965291|uniprotkb:A8K6J4|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938|ensembl:ENSP00000272928 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505067|imex:IM-28562-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_016860005.1|refseq:NP_064707.1|refseq:XP_005246154.1|refseq:XP_005246155.1|ensembl:ENSG00000144476(gene)|ensembl:ENST00000272928(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6K3F|reactome:R-HSA-380108|reactome:R-HSA-418594 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.03"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606 rigid:jTpyY5o3+FwTpbO4oyxmgbl+GH0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P28749 intact:EBI-26504932 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505056|imex:IM-28562-887 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 34.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:LHGo83ribZ8CWYglEIaJIVWHny4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P38936 intact:EBI-26504932 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505045|imex:IM-28562-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 3.85"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:B541qX58bDxHYR+6H0vDQMs49qw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P13928 intact:EBI-26504932 intact:EBI-2556915|intact:EBI-2556840|uniprotkb:A6NDE6|uniprotkb:B4DKI1|uniprotkb:Q5T2P8|uniprotkb:B4DTC9|uniprotkb:A6NLM1|uniprotkb:Q6GMY3|uniprotkb:Q5VTM4|uniprotkb:Q9BT34|intact:EBI-2556866|ensembl:ENSP00000462880 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:anxa8_human(display_long)|uniprotkb:ANXA8(gene name)|psi-mi:ANXA8(display_short)|uniprotkb:ANX8(gene name synonym)|uniprotkb:Annexin-8(gene name synonym)|uniprotkb:Annexin VIII(gene name synonym)|uniprotkb:Vascular anticoagulant-beta(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505034|imex:IM-28562-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001035173.1|ensembl:ENSG00000265190(gene)|ensembl:ENST00000585281(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|interpro:IPR001464(Annexin)|interpro:IPR009115(Annexin, type VIII)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P13928|rcsb pdb:1W3W|rcsb pdb:1W45|refseq:NP_001258631.1|refseq:NP_001258632.1|refseq:NP_001092315.2 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.56"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:rll8P+B85DfPz6rMIDpqo7XwlrQ9606 rigid:r/Hfa4zPXbL3I1+GYrGM3Jdd+L0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P16144 intact:EBI-26504932 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505023|imex:IM-28562-1061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 251.33"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:GGCM5F6R4d5z99IcfPqEFPEij+0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:P29590 intact:EBI-26504932 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505012|imex:IM-28562-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 17.06"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:bHkvIme+N7nbmVPUK/xjnkYUcF8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:Q84292 uniprotkb:Q15005 intact:EBI-26504932 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505001|imex:IM-28562-711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 12.11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:cb1HnFI3soCRouGT3F/cc/ntQl0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P68104 intact:EBI-866453 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505555|imex:IM-28562-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 133.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:8m0+U5NcM9ANm2XK7lDflFX0I8g false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P28749 intact:EBI-866453 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505544|imex:IM-28562-1077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 124.20"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:Jjk+W3T+3FqW/RuMPPnGb+5Kyrs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P12004 intact:EBI-866453 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505533|imex:IM-28562-1229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 12.75"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:/IcPezD4xnujO0GmbL3Xp09qFao false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q9UBS4 intact:EBI-866453 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505522|imex:IM-28562-903 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 12.56"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:0pHPcaK+JqnkqazwT4c9U3ZhF14 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q9UHC7 intact:EBI-866453 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505511|imex:IM-28562-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 12.46"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:dag+gN5s9WKzo9ZeN+1+OnhcjCA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P39023 intact:EBI-866453 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505500|imex:IM-28562-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 10.70"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:m9EtaUzHZDFbtf8T5SHq4bZ+IMA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q99729 intact:EBI-866453 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505489|imex:IM-28562-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 10.34"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:zR6msc+m5IpmISsWP9n2MMXcG0Y false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:Q16831 intact:EBI-26505276 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505478|imex:IM-28562-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.51"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:RdylJ3iaeb+i6B+5fx0B8wDgOwY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:Q9UNK0 intact:EBI-26505276 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505467|imex:IM-28562-721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.50"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:lLSqMeQ12Q+RAVb4np5/uFtSGYk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P20618 intact:EBI-26505276 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505456|imex:IM-28562-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:0QYaQ8j4nX/2oumzYKx9Hb45cro false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P12004 intact:EBI-26505276 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505445|imex:IM-28562-719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.06"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:vg3/FdepDbuxGLL4h0FcI/I9lyU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:Q9UBS4 intact:EBI-26505276 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505434|imex:IM-28562-717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.69"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:nDFzZG6NanQ6DqFSOdYmx/Du+8U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:Q9UHC7 intact:EBI-26505276 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505423|imex:IM-28562-1227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:cVQutJPjMWrUnY39IY+XQR9zT9E false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P06733 intact:EBI-26505276 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505412|imex:IM-28562-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.47"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:bKOOsCab7hx7fHcqX8Wv1bXHwjc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:O15160 intact:EBI-26505276 intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505401|imex:IM-28562-1225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.80"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606 rigid:zbT5HLD8uJxN5Bd1XlLkgg5q7kY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P10914 intact:EBI-26505276 intact:EBI-1055781|uniprotkb:Q96GG7|ensembl:ENSP00000245414|ensembl:ENSP00000384406 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:irf1_human(display_long)|uniprotkb:IRF1(gene name)|psi-mi:IRF1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505390|imex:IM-28562-1075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002189.1|ensembl:ENSG00000125347(gene)|ensembl:ENST00000245414(transcript)|ensembl:ENST00000405885(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043374"(CD8-positive, alpha-beta T cell differentiation)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031215|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231|dip:DIP-40988N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.74"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:ToPrN31Dt6/EQuaX8gkxFBDJp5Q9606 rigid:RZgvFRLiCHEVl4F6RWRPWQJGoss false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P14618 intact:EBI-26505276 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505379|imex:IM-28562-1223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.55"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:+r3xpsgFGIlcCHIcL8x3MOu49hk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P50479 intact:EBI-26505276 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505368|imex:IM-28562-715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.31"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:oxqGNTQ+4QdYkdBZMhdmnm9HeaI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P38936 intact:EBI-26505276 intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505357|imex:IM-28562-901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.03"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606 rigid:Y+4PlSC49pWSpDeGZYEzULpn2ws false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P39023 intact:EBI-26505276 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505346|imex:IM-28562-899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:ASmA0oukPam3Ypqeb0tBoktqyII false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P25106 intact:EBI-26505276 intact:EBI-1965291|uniprotkb:A8K6J4|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938|ensembl:ENSP00000272928 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505335|imex:IM-28562-897 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_016860005.1|refseq:NP_064707.1|refseq:XP_005246154.1|refseq:XP_005246155.1|ensembl:ENSG00000144476(gene)|ensembl:ENST00000272928(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6K3F|reactome:R-HSA-380108|reactome:R-HSA-418594 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.75"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606 rigid:UrGjVBu2yLSoXt/XZPkTlEWOAEs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:Q99729 intact:EBI-26505276 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505324|imex:IM-28562-895 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:HY0komJ8TR31o/VTBpo8JYfpXFc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P29590 intact:EBI-26505276 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505313|imex:IM-28562-1073 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 25.84"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:/W8imOWlTEjajD9pRfChPsW9N2U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P28749 intact:EBI-26505276 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505302|imex:IM-28562-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 14.45"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:mUYeuQLv7n8/mgB9lUUY+j3EUbs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36817 uniprotkb:P16144 intact:EBI-26505276 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505291|imex:IM-28562-1071 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 11.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:b6W19XkfpUifAd729Z4Xc2b4/NM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:P16144 intact:EBI-11722553 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505265|imex:IM-28562-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.31"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:0pp/Cs8rlXU4iLaaL55s0dM2cxE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06430 uniprotkb:P50479 intact:EBI-11722553 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv08(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505254|imex:IM-28562-893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.08"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:p9vIKuSZDgt8rOOX64xfro1/Z5o10579 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:oGt5H9gOKk2rVOOpT0ziV5cHC1o false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P50479 intact:EBI-1776887 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505830|imex:IM-28562-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 11.35"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:pH/yyxJwfJMh6c7ByVrTbwfB0ng false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P06400 intact:EBI-26506039 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506065|imex:IM-28562-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 13.09"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:6Q6bGzH2sg6y3liKex/NXmbRwlA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P14618 intact:EBI-26506039 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506054|imex:IM-28562-739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 11.00"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:Rn88nKCdgX346N9O6pC4Rbpft5c false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:Q15005 intact:EBI-1776887 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506028|imex:IM-28562-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.68"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:Vj0rjPmGcopwiWrFBtfckK2FHQY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:Q16831 intact:EBI-1776887 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506017|imex:IM-28562-917 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.56"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:BvZoueLSG7OsiGbQl0t7/+usFm0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P04632 intact:EBI-1776887 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506006|imex:IM-28562-737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 8.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:UWJY69AuVfT4bDRcPyabYSxMngE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P14618 intact:EBI-1776887 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505995|imex:IM-28562-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 7.61"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:wf9kEfmeU60mYgsPiClfTrSi/Ng false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P12004 uniprotkb:P06788 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 intact:EBI-1776887 psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505984|imex:IM-28562-1245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rigid:zBe2sAxUiVPV18WFNR3DdEd3J10 false gaussia-n:n-n gaussia-c:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P13667 intact:EBI-1776887 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505973|imex:IM-28562-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.80"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:c272A5N28OEI5LelNGtifhcUuig false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P20618 intact:EBI-1776887 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505962|imex:IM-28562-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:3Y6S/GhPbQ3ikOl0n7D/0PALKgs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P60709 intact:EBI-1776887 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505951|imex:IM-28562-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.02"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rigid:2uFIqMLnKXIYf1MDO5nnhGi2RQM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P16144 intact:EBI-1776887 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505940|imex:IM-28562-1089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.39"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:brju/gVBp/kZuM/sg7nFeDBsf3o false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P39023 intact:EBI-1776887 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505929|imex:IM-28562-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.96"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:nlPzJAZGsvvf2MaPQWdLf9gSc0A false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:Q13362 intact:EBI-1776887 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505918|imex:IM-28562-735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.61"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 rigid:aOfp+MqTMcN6BkAxHIraeJJKPHE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P68104 intact:EBI-1776887 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505907|imex:IM-28562-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.34"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:r3zzyo5YbgkZD4qrpqDHVP9YgYU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:Q9UHC7 intact:EBI-1776887 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505896|imex:IM-28562-733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.83"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:HCUz1OA6TwqVPCEtI/XHmHNXKck false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:Q9UNK0 intact:EBI-1776887 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505885|imex:IM-28562-731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.79"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:uiQs09sS53Ln2skFxvKkZSgg+xY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P28749 intact:EBI-1776887 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505874|imex:IM-28562-915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 25.65"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:DQIF9CGeKreDPCuceqkR/ICNImQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P06400 intact:EBI-1776887 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505863|imex:IM-28562-729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 19.39"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:ndxlGUft3kWHLNPbCgpvC60HB1k false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:P29590 intact:EBI-1776887 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505852|imex:IM-28562-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 11.65"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:r7Aodtn1sFYQiMJGi1kzWSTrzr8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06788 uniprotkb:Q9UBS4 intact:EBI-1776887 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505841|imex:IM-28562-913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 11.48"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:8ABDOCtBLppquFoeb22HZ+2qTzU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:O94842 intact:EBI-866453 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505819|imex:IM-28562-727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:wtw9ZLC0YwKeLcWiga1d3XgUnLU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q15005 intact:EBI-866453 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505808|imex:IM-28562-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.49"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:9Qs2gJftvca5DL3FlewKplUiCXE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q14168 intact:EBI-866453 intact:EBI-3046657|uniprotkb:Q53ES9|uniprotkb:Q9BQJ2|uniprotkb:Q5CZB9|uniprotkb:E7EX01|uniprotkb:B4DGE9|uniprotkb:B4DRJ0|uniprotkb:B7Z3G8|uniprotkb:E7EV80|uniprotkb:E7EV91 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mpp2_human(display_long)|uniprotkb:MPP2(gene name)|psi-mi:MPP2(display_short)|uniprotkb:DLG2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Protein MPP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505797|imex:IM-28562-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_005365.4|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:2E7K|refseq:NP_001265305.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|refseq:NP_001265299.1|refseq:NP_001265300.1|refseq:NP_001265301.1|refseq:NP_001265302.1|refseq:NP_001265303.1|refseq:NP_001265304.1|refseq:NP_001265310.1|interpro:IPR035602|mint:Q14168|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 8.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:V/6k8hS86wWuXs+iU37my9MOYtc9606 rigid:9BlD5GVWFDjCNZJFl49EPAve17I false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q9UNK0 intact:EBI-866453 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505786|imex:IM-28562-1239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.42"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:wSCnyONDdcGNYwpXMoqiO5nq4Ps false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P25106 intact:EBI-866453 intact:EBI-1965291|uniprotkb:A8K6J4|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938|ensembl:ENSP00000272928 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505775|imex:IM-28562-1237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:XP_016860005.1|refseq:NP_064707.1|refseq:XP_005246154.1|refseq:XP_005246155.1|ensembl:ENSG00000144476(gene)|ensembl:ENST00000272928(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6K3F|reactome:R-HSA-380108|reactome:R-HSA-418594 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606 rigid:dXEg5ffotmh5yeytP0p8df5ENrQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q16831 intact:EBI-866453 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505764|imex:IM-28562-911 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.73"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:8jFPDh97XAFF09qycRV3xizSIwo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P50479 intact:EBI-866453 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505753|imex:IM-28562-1235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.70"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:IU3tRR76ZaCG2gx1zzo0XBwPeOM false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P06733 intact:EBI-866453 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505742|imex:IM-28562-1233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.53"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:ilWb4DIursWRqVjBMBiMShk3IyY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q96EK4 intact:EBI-866453 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505731|imex:IM-28562-1231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST7|comment:"Normalized luminescence ratios: 6.09"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:xeNHnonItoDq/nIamXq40ct6w3Y false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P26641 intact:EBI-866453 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505720|imex:IM-28562-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 rigid:vAOnYahKXfq1KIdnpu4H/WB/iLs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P04632 intact:EBI-866453 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505709|imex:IM-28562-1087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 5.86"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:sFGwPOXBQeyRcVZSPfyW33u1B98 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:O60814 intact:EBI-866453 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505698|imex:IM-28562-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.30"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 rigid:/ZzBNuR0kVlsmgMtwk9dfYCA/Os false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P05549 intact:EBI-866453 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505687|imex:IM-28562-909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:2DEOL7BbHvwbv3LSMqW5SWsZya4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q96EY1 intact:EBI-866453 intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505676|imex:IM-28562-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.82"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606 rigid:fcgQq4Vw4Iwk5Qy9gsq5eakPYEo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P29590 intact:EBI-866453 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505665|imex:IM-28562-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 38.76"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:LRP9ZePZbmohUqfT4b+KIByt7UE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q9NQ31 intact:EBI-866453 intact:EBI-517035|uniprotkb:Q8NBS2|uniprotkb:Q8TAC6|uniprotkb:Q8TAD3|uniprotkb:Q8TAE0|ensembl:ENSP00000310459|ensembl:ENSP00000431331 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:akip1_human(display_long)|uniprotkb:Breast cancer-associated gene 3 protein(gene name synonym)|uniprotkb:PKA-interacting protein(gene name synonym)|uniprotkb:AKIP1(gene name)|psi-mi:AKIP1(display_short)|uniprotkb:BCA3(gene name synonym)|uniprotkb:C11orf17(gene name synonym)|uniprotkb:Proline-rich protein BCA3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505654|imex:IM-28562-1079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001193575.1|refseq:NP_001193576.1|refseq:NP_001193577.1|refseq:NP_065693.2|refseq:XP_016873500.1|ensembl:ENSG00000166452(gene)|ensembl:ENST00000309377(transcript)|ensembl:ENST00000534147(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR033214 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.72"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:EdMopChLAM1kUZUfo5Z9IBU0Vyg9606 rigid:mzsb3BsDjpds3xPpUg8TfLqmZFo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P60709 intact:EBI-866453 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505643|imex:IM-28562-725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.57"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rigid:dmpPUcOoGCAJ52o9czaVIQW9mTU false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q9UHR5 intact:EBI-866453 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505632|imex:IM-28562-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.52"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rigid:r4sFUPHsMvfhTZr2drtWvRCu6lc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P16144 intact:EBI-866453 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505621|imex:IM-28562-907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 28.74"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:0x0fiDmbkkJTmE8qDWe38rYt8QY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P06400 intact:EBI-866453 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505610|imex:IM-28562-905 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 27.26"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:2KFOorHveQrcEJ23StbMX8Bc8Zs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P14618 intact:EBI-866453 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505599|imex:IM-28562-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 21.42"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:63niwwEiGrPFRyOUHcjL7gGwST8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:Q9Y6Q5 intact:EBI-866453 intact:EBI-752250|uniprotkb:Q9BSI8|uniprotkb:B2RDV5|ensembl:ENSP00000250244 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap1m2_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-2 subunit(gene name synonym)|uniprotkb:Mu-adaptin 2(gene name synonym)|uniprotkb:AP-mu chain family member mu1B(gene name synonym)|uniprotkb:Mu1B-adaptin(gene name synonym)|uniprotkb:AP1M2(gene name)|psi-mi:AP1M2(display_short)|uniprotkb:Adaptor protein complex AP-1 subunit mu-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-2 medium chain 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505588|imex:IM-28562-723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_005489.2|refseq:NP_001287816.1|ensembl:ENSG00000129354(gene)|ensembl:ENST00000250244(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 17.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:Zb94TVE2hogjzn1QKDV3vWRNsWo9606 rigid:1bWNmz4VYICE9a2VEJO0pWQhh4Y false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P20618 intact:EBI-866453 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505577|imex:IM-28562-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 15.05"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:tr1kT74eyPTEiyYT+KpBGR8lGs0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P03129 uniprotkb:P17936 intact:EBI-866453 intact:EBI-715709|uniprotkb:Q2V509|uniprotkb:Q6P1M6|uniprotkb:A4D2F5|uniprotkb:Q9UCL4|uniprotkb:D3DVM0|ensembl:ENSP00000477772 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ibp3_human(display_long)|uniprotkb:IGFBP3(gene name)|psi-mi:IGFBP3(display_short)|uniprotkb:IBP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26505566|imex:IM-28562-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_000589.2|refseq:NP_001013416.1|ensembl:ENSG00000146674(gene)|ensembl:ENST00000613132(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012211(Insulin-like growth factor binding protein 3)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|mint:P17936|reactome:R-HSA-381426|reactome:R-HSA-6803211|reactome:R-HSA-8957275|refseq:XP_016867641.1|dip:DIP-40786N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 14.68"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:zb2NzKqdY6oCXbF/DrT5etyMeEU9606 rigid:WlowHDNu9bOx3WbbM18JA/fS+Ls false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P28749 intact:EBI-26506039 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506120|imex:IM-28562-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 30.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:lZEM3kvacZmxatPteIHHTj5ln44 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P13667 intact:EBI-26506039 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506109|imex:IM-28562-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.60"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:2mBKcQ89y1GiklxK7WQ63Go3fk0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q8IZC6 intact:EBI-26506039 intact:EBI-2529384|uniprotkb:Q66K43|uniprotkb:Q96JF7|ensembl:ENSP00000348385 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cora1_human(display_long)|uniprotkb:COL27A1(gene name)|psi-mi:COL27A1(display_short)|uniprotkb:KIAA1870(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506098|imex:IM-28562-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000196739(gene)|ensembl:ENST00000356083(transcript)|go:"GO:0003431"(growth plate cartilage chondrocyte development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005583"(fibrillar collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_116277.2 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.50"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:+Hwz0vac4YiN3eiJr0WxgHuQsiM9606 rigid:/LIDENLG45nTI0Ya6d67sj3wI3I false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P29590 intact:EBI-26506039 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506087|imex:IM-28562-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 25.32"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:q6gRFtF+/3sWh9NQMxC3415pV5Q false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q9UNK0 intact:EBI-26506039 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506076|imex:IM-28562-1091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 13.69"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:b1t1ICZ8AXMjwUyNaY3PRsP3+Co false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P20618 intact:EBI-26506039 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506241|imex:IM-28562-1247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.63"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:pYgjejHIDWj3KBVrBZUkMCwRvJw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P50479 intact:EBI-26506039 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506230|imex:IM-28562-927 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.56"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:7HF4HA2VOWQiAdP33DTKWp3n3wY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P12004 intact:EBI-11737199 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506351|imex:IM-28562-1251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.95"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:6kHSGk7FbOCo8b2xgjR5/gUqJwI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:O75376 intact:EBI-11737199 intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506340|imex:IM-28562-1249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.82"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606 rigid:YeZuZKdaFaRjQ34cC77O+4P4hZk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P28749 intact:EBI-11737199 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506329|imex:IM-28562-933 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 184.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:rYgmINUzMpw/CyLhRpF2pmX4V8Q false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P17936 intact:EBI-11737199 intact:EBI-715709|uniprotkb:Q2V509|uniprotkb:Q6P1M6|uniprotkb:A4D2F5|uniprotkb:Q9UCL4|uniprotkb:D3DVM0|ensembl:ENSP00000477772 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ibp3_human(display_long)|uniprotkb:IGFBP3(gene name)|psi-mi:IGFBP3(display_short)|uniprotkb:IBP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506318|imex:IM-28562-931 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_000589.2|refseq:NP_001013416.1|ensembl:ENSG00000146674(gene)|ensembl:ENST00000613132(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012211(Insulin-like growth factor binding protein 3)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|mint:P17936|reactome:R-HSA-381426|reactome:R-HSA-6803211|reactome:R-HSA-8957275|refseq:XP_016867641.1|dip:DIP-40786N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 18.14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:zb2NzKqdY6oCXbF/DrT5etyMeEU9606 rigid:L8pQxNrmbMxjeBORF/0dx4rjS5M false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P29590 intact:EBI-11737199 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506307|imex:IM-28562-747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 13.58"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:1ryL2FuIHYVBfQGpFjCEdUQAr+I false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q9UHC7 intact:EBI-26506039 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506296|imex:IM-28562-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.98"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:hMmieXSdrpJVYRnv8I1rYFTAObk false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P68104 intact:EBI-26506039 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506285|imex:IM-28562-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.94"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:1LKCAaDR5ClkDCLN0W2UP8ujFGY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q15005 intact:EBI-26506039 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506274|imex:IM-28562-929 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.62"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:Cwef1dIVqAcUfR+hf/pk9sCzKoA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P12004 intact:EBI-26506039 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506263|imex:IM-28562-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:Il5vLaYQiX7AliFHVj3yOxRtZd4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q99729 intact:EBI-26506039 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506252|imex:IM-28562-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.82"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:u/ldogoe6gqxbyn2noKwCGnjfjE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q96EK4 intact:EBI-26506039 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506219|imex:IM-28562-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST7|comment:"Normalized luminescence ratios: 5.35"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:9zmEHmSfTqqjuEo6JoRy4UgTzqY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q9UBS4 intact:EBI-26506039 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506208|imex:IM-28562-925 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.35"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:esGh/RxbItIxhtqGiEf6I65JAQ4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P17936 intact:EBI-26506039 intact:EBI-715709|uniprotkb:Q2V509|uniprotkb:Q6P1M6|uniprotkb:A4D2F5|uniprotkb:Q9UCL4|uniprotkb:D3DVM0|ensembl:ENSP00000477772 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ibp3_human(display_long)|uniprotkb:IGFBP3(gene name)|psi-mi:IGFBP3(display_short)|uniprotkb:IBP3(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506197|imex:IM-28562-745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000589.2|refseq:NP_001013416.1|ensembl:ENSG00000146674(gene)|ensembl:ENST00000613132(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012211(Insulin-like growth factor binding protein 3)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|mint:P17936|reactome:R-HSA-381426|reactome:R-HSA-6803211|reactome:R-HSA-8957275|refseq:XP_016867641.1|dip:DIP-40786N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:zb2NzKqdY6oCXbF/DrT5etyMeEU9606 rigid:q6EVWnD8qf8SxftF7ERU6SBtAWg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P39023 intact:EBI-26506039 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506186|imex:IM-28562-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.52"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:BOVGt0SmvjDRz6oc6QbKZYH8D1Y false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q9Y6Q5 intact:EBI-26506039 intact:EBI-752250|uniprotkb:Q9BSI8|uniprotkb:B2RDV5|ensembl:ENSP00000250244 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap1m2_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-2 subunit(gene name synonym)|uniprotkb:Mu-adaptin 2(gene name synonym)|uniprotkb:AP-mu chain family member mu1B(gene name synonym)|uniprotkb:Mu1B-adaptin(gene name synonym)|uniprotkb:AP1M2(gene name)|psi-mi:AP1M2(display_short)|uniprotkb:Adaptor protein complex AP-1 subunit mu-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-2 medium chain 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506175|imex:IM-28562-923 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_005489.2|refseq:NP_001287816.1|ensembl:ENSG00000129354(gene)|ensembl:ENST00000250244(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:Zb94TVE2hogjzn1QKDV3vWRNsWo9606 rigid:NWkDH/Bq4PtQeLTnxOQ8rsN1y/g false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P25106 intact:EBI-26506039 intact:EBI-1965291|uniprotkb:A8K6J4|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938|ensembl:ENSP00000272928 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506164|imex:IM-28562-1093 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_016860005.1|refseq:NP_064707.1|refseq:XP_005246154.1|refseq:XP_005246155.1|ensembl:ENSG00000144476(gene)|ensembl:ENST00000272928(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6K3F|reactome:R-HSA-380108|reactome:R-HSA-418594 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.23"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606 rigid:nb9kHcF2y2doNmzglHGabMUH+PI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q14168 intact:EBI-26506039 intact:EBI-3046657|uniprotkb:Q53ES9|uniprotkb:Q9BQJ2|uniprotkb:Q5CZB9|uniprotkb:E7EX01|uniprotkb:B4DGE9|uniprotkb:B4DRJ0|uniprotkb:B7Z3G8|uniprotkb:E7EV80|uniprotkb:E7EV91 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mpp2_human(display_long)|uniprotkb:MPP2(gene name)|psi-mi:MPP2(display_short)|uniprotkb:DLG2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Protein MPP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506153|imex:IM-28562-921 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_005365.4|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:2E7K|refseq:NP_001265305.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|refseq:NP_001265299.1|refseq:NP_001265300.1|refseq:NP_001265301.1|refseq:NP_001265302.1|refseq:NP_001265303.1|refseq:NP_001265304.1|refseq:NP_001265310.1|interpro:IPR035602|mint:Q14168|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 4.07"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:V/6k8hS86wWuXs+iU37my9MOYtc9606 rigid:LsjYiL0/OKM4jI3VXkzYvKdPmew false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:P16144 intact:EBI-26506039 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506131|imex:IM-28562-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 38.88"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:btvOwlP9oPeSjWEvNiaPyd3CmDE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P36827 uniprotkb:Q16831 intact:EBI-26506039 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506142|imex:IM-28562-919 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.03"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:ohH4IwBj4pYirdoumCTQv6ZUBQ8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P50479 intact:EBI-26506516 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506651|imex:IM-28562-755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.86"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:3ZlpCTkNufKI2izEAeLHrQO9rvg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:Q15005 intact:EBI-26506516 intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506640|imex:IM-28562-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.41"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606 rigid:Od4ohvqa70qYJtc08eRMuMKCy0o false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:Q16831 intact:EBI-26506516 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506629|imex:IM-28562-959 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.06"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:jZI6M7asyCDtOo+6auvjCmYEWDA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P20618 intact:EBI-26506516 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506618|imex:IM-28562-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.98"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:/EHnNA+N/BdG/wwe+I2lQqiWhzo false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:Q8IZC6 intact:EBI-26506516 intact:EBI-2529384|uniprotkb:Q66K43|uniprotkb:Q96JF7|ensembl:ENSP00000348385 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cora1_human(display_long)|uniprotkb:COL27A1(gene name)|psi-mi:COL27A1(display_short)|uniprotkb:KIAA1870(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506607|imex:IM-28562-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000196739(gene)|ensembl:ENST00000356083(transcript)|go:"GO:0003431"(growth plate cartilage chondrocyte development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005583"(fibrillar collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_116277.2 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.90"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:+Hwz0vac4YiN3eiJr0WxgHuQsiM9606 rigid:RUn79y7aW8kav8myaMNk/PKbpQg false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P04632 intact:EBI-26506516 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506596|imex:IM-28562-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 3.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:zKgmBhBJfcLN/DhZMDoYOrcjdk0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P12004 intact:EBI-26506516 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506684|imex:IM-28562-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:3NCRVM+WekuTHlWi8MiSElfiH60 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P16144 intact:EBI-26506516 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506673|imex:IM-28562-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.34"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:x11l2Tf9vTwCRH6s5ysxMXuaiTs false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:Q9UNK0 intact:EBI-26506516 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506662|imex:IM-28562-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.27"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:86JBLIKURyUPno0SWToOWeR1nzw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:Q9UHC7 intact:EBI-26506516 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506585|imex:IM-28562-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.75"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:nslKQVJ1NYQ3tGldUAkF3SQMZxA false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P39023 intact:EBI-26506516 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506574|imex:IM-28562-957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 3.56"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:GJ242EF0YuZBRUYkC21LGY6PEpY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P06400 intact:EBI-26506516 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506563|imex:IM-28562-1097 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 3.55"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:/jc0B2nrXw6TlXUo/JED/gxCL8U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P28749 intact:EBI-26506516 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506552|imex:IM-28562-955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 20.61"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:f+CFx0VgzdY6DAS3BrBobB/WykI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P68104 intact:EBI-26506516 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506541|imex:IM-28562-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 141.02"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:pXh0+l2szoh1VbpJ11A/yfeQpSc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P29590 intact:EBI-26506516 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506530|imex:IM-28562-753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 10.21"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:RSYQYPa1qH1ctSupR24rWv/QTJc false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P25685 intact:EBI-11737199 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506505|imex:IM-28562-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:ST7|comment:"Normalized luminescence ratios: 9.54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:a79bOf3n4S4RCCKYC7uUmZxnw6c false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P14618 intact:EBI-11737199 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506494|imex:IM-28562-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 9.26"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:q9gGQ58LKYT4/SjZRchJ4Egw4qQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P39023 intact:EBI-11737199 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506483|imex:IM-28562-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 7.42"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 rigid:+yCYA0U+Vr/8/kZh0J2mR8iC4GI false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P50479 intact:EBI-11737199 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506472|imex:IM-28562-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:sST9otCq4aveFke5Wr1RZXJABJw false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:Q9UHC7 intact:EBI-11737199 intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506461|imex:IM-28562-953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:XP_011514299.1|refseq:XP_011514300.1|refseq:NP_001138597.1|refseq:NP_038474.2|ensembl:ENSP00000255977|ensembl:ENST00000443720|ensembl:ENSP00000416369|ensembl:ENST00000474576|ensembl:ENSP00000417863|ensembl:ENSG00000133606(gene)|ensembl:ENST00000255977(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.61"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606 rigid:CKmb4Yvz+LGc4nYsfOr1m/c4830 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:Q14168 intact:EBI-11737199 intact:EBI-3046657|uniprotkb:Q53ES9|uniprotkb:Q9BQJ2|uniprotkb:Q5CZB9|uniprotkb:E7EX01|uniprotkb:B4DGE9|uniprotkb:B4DRJ0|uniprotkb:B7Z3G8|uniprotkb:E7EV80|uniprotkb:E7EV91 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mpp2_human(display_long)|uniprotkb:MPP2(gene name)|psi-mi:MPP2(display_short)|uniprotkb:DLG2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Protein MPP2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506450|imex:IM-28562-939 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_005365.4|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:2E7K|refseq:NP_001265305.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|refseq:NP_001265299.1|refseq:NP_001265300.1|refseq:NP_001265301.1|refseq:NP_001265302.1|refseq:NP_001265303.1|refseq:NP_001265304.1|refseq:NP_001265310.1|interpro:IPR035602|mint:Q14168|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 6.31"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:V/6k8hS86wWuXs+iU37my9MOYtc9606 rigid:v88hpNlFV90DIghlrC6dxN4mBC4 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:Q99729 intact:EBI-11737199 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506439|imex:IM-28562-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.20"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:PUQiH9Lf1jiNLC+5fsiPQZseZAE false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P05549 intact:EBI-11737199 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506428|imex:IM-28562-751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 6.08"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rigid:wsYw520JkqrhxuTL29SZb+9Rbl8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P16144 intact:EBI-11737199 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506417|imex:IM-28562-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 5.44"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:5H8vmoDu8h22/M7p/G/KBiS51m8 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:Q96EK4 intact:EBI-11737199 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506406|imex:IM-28562-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST7|comment:"Normalized luminescence ratios: 4.72"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:V/2GyLHWD+sohCIZ29dn0SFPh3U false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P20618 intact:EBI-11737199 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506395|imex:IM-28562-749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.40"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:T6ZHrGXcE9SiyxvQ4s107wQqCZ0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P25106 intact:EBI-11737199 intact:EBI-1965291|uniprotkb:A8K6J4|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938|ensembl:ENSP00000272928 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506384|imex:IM-28562-1095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:XP_016860005.1|refseq:NP_064707.1|refseq:XP_005246154.1|refseq:XP_005246155.1|ensembl:ENSG00000144476(gene)|ensembl:ENST00000272928(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6K3F|reactome:R-HSA-380108|reactome:R-HSA-418594 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.22"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606 rigid:i0nqe6MFdZQlb08dCeBqFigRjbQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:Q16831 intact:EBI-11737199 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506373|imex:IM-28562-937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:ST7|comment:"Normalized luminescence ratios: 4.10"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:XEuz9h5xSDiZA5dcVL1Rk2PIuA0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06429 uniprotkb:P06400 intact:EBI-11737199 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506362|imex:IM-28562-935 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 33.64"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:9d+OPtUtfa1TZm182BPpOzqbCsQ false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P13667 intact:EBI-26506516 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506707|imex:IM-28562-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:ST7|comment:"Normalized luminescence ratios: 8.77"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:cfKjZyTzm0QBeoUibF+WTGKe/lY false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P24837 uniprotkb:P14618 intact:EBI-26506516 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1203"(split luciferase complementation) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506696|imex:IM-28562-1099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST7 F4B|comment:"Normalized luminescence ratios: 8.09"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:iia8k/I//SCUvuICf5z6SiPJ4o0 false gaussia-c:n-n gaussia-n:n-n - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P06930 uniprotkb:P61769 intact:EBI-10917424 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506920|imex:IM-28562-1129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rigid:6VRD8uLMSbt9LSURzJnDezACraI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q66K74 intact:EBI-10917424 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506913|imex:IM-28562-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:o9sB7Z3vZBLQC5r0igIcJP14iZg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q9NX07 intact:EBI-10917424 intact:EBI-12581310|uniprotkb:Q86SU7|ensembl:ENSP00000362936 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tsap1_human(display_long)|uniprotkb:TRNAU1AP(gene name)|psi-mi:TRNAU1AP(display_short)|uniprotkb:SECP43(gene name synonym)|uniprotkb:SECp43(gene name synonym)|uniprotkb:TRSPAP1(gene name synonym)|uniprotkb:tRNA selenocysteine-associated protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506906|imex:IM-28562-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_060316.1|refseq:XP_016857031.1|ensembl:ENSG00000180098(gene)|ensembl:ENST00000373830(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034510|interpro:IPR035979|interpro:IPR040434|interpro:IPR041085|rcsb pdb:2DHG|rcsb pdb:2DIV - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:lGfESQymIzEeGCPSK1lVTJqhypE9606 rigid:p7iRX2ppfEtCuTxAeb60rwpAfdY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q16584 intact:EBI-10917424 intact:EBI-49961|uniprotkb:Q53H00|uniprotkb:Q59F06|uniprotkb:Q6P2G4|uniprotkb:B4DS76|ensembl:ENSP00000309597 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:m3k11_human(display_long)|uniprotkb:MAP3K11(gene name)|psi-mi:MAP3K11(display_short)|uniprotkb:Mixed lineage kinase 3(gene name synonym)|uniprotkb:Src-homology 3 domain-containing proline-rich kinase(gene name synonym)|uniprotkb:SPRK(gene name synonym)|uniprotkb:PTK1(gene name synonym)|uniprotkb:MLK3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506899|imex:IM-28562-767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002410.1|ensembl:ENSG00000173327(gene)|ensembl:ENST00000309100(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|mint:Q16584|rcsb pdb:5K26|rcsb pdb:5K28|rcsb pdb:6AQB|rcsb pdb:6CQ7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-9013148|reactome:R-HSA-9013408|reactome:R-HSA-9649948 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:njuMQIbuVFlWXNggegg3zYAKmS49606 rigid:YLe1gT/Za+GzoOVMZcDpH/PkgBo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:P50616 intact:EBI-10917424 intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506892|imex:IM-28562-965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606 rigid:MkToMk+N875gsFvy5Qxquyfc7+c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q96N11 intact:EBI-10917424 intact:EBI-718667|uniprotkb:Q9BQ43|ensembl:ENSP00000340220 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cg026_human(display_long)|uniprotkb:C7orf26(gene name)|psi-mi:C7orf26(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506885|imex:IM-28562-1127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_076972.2|refseq:NP_001289968.1|ensembl:ENSG00000146576(gene)|ensembl:ENST00000344417(transcript)|interpro:IPR027844 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:BURe1wh7SN0dkYBaMmJ51w/W+qA9606 rigid:ts6r7roJpqBJKyAguprOzZV4LmM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q9UBF8 intact:EBI-10917424 intact:EBI-1053214|uniprotkb:B4DGI2|uniprotkb:O15096|uniprotkb:P78405|uniprotkb:Q5VWC1|uniprotkb:Q9BWR6|uniprotkb:Q5VWB9|uniprotkb:Q5VWC0|ensembl:ENSP00000357867 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pi4kb_human(display_long)|uniprotkb:NPIK(gene name synonym)|uniprotkb:PI4K92(gene name synonym)|uniprotkb:PI4KIII(gene name synonym)|uniprotkb:PI4KB(gene name)|psi-mi:PI4KB(display_short)|uniprotkb:PIK4CB(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506878|imex:IM-28562-963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001185702.1|refseq:NP_001185703.1|refseq:NP_001185704.1|refseq:NP_002642.1|ensembl:ENSG00000143393(gene)|ensembl:ENST00000368873(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR018936|interpro:IPR036940|mint:Q9UBF8|rcsb pdb:2N73|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4WAE|rcsb pdb:4WAG|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5LX2|rcsb pdb:5NAS|rcsb pdb:6GL3|reactome:R-HSA-1660514|refseq:NP_001317650.1|refseq:XP_016856979.1|refseq:XP_016856980.1|refseq:XP_016856981.1|dip:DIP-42267N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:EeU4q6eJ1Kji9EaWCT+xYv2Y8eA9606 rigid:8Ag3stvN/AuFbRopoodUELndDM8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q02878 intact:EBI-10917424 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506871|imex:IM-28562-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:HjpCK0DIw+fGvxle3OU6rcQ4I6c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:O94885 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506864|imex:IM-28562-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:+3gmzpZqQAs8569jEDZ3+fmoBcs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:Q13263 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506857|imex:IM-28562-765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:UdG3P6XRpN2rkSWf46RiPrs7gEc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:P03891 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-1246202|uniprotkb:Q34769|uniprotkb:Q9TGI0|uniprotkb:Q9TGI1|uniprotkb:Q9TGI2|uniprotkb:Q9TGI3|uniprotkb:Q9TGI4|ensembl:ENSP00000355046 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:nu2m_human(display_long)|uniprotkb:MT-ND2(gene name)|psi-mi:MT-ND2(display_short)|uniprotkb:MTND2(gene name synonym)|uniprotkb:NADH2(gene name synonym)|uniprotkb:ND2(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506850|imex:IM-28562-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:YP_003024027.1|ensembl:ENSG00000198763(gene)|ensembl:ENST00000361453(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003917(NADH-ubiquinone oxidoreductase, chain 2)|interpro:IPR010933(NADH dehydrogenase subunit 2, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:GKiEviD5+IEk1TCxgEvUyw6Ys6s9606 rigid:gjUqn2YJuNiUZJv0DCEedjgSEs8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:Q9HB07 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-709754|ensembl:ENSP00000267103|uniprotkb:Q86UA3|intact:EBI-10258793 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506843|imex:IM-28562-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000139637(gene)|ensembl:ENST00000267103(transcript)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035641"(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|refseq:NP_067653.3 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:k6ea0h/OMRODp3PQjed6sdxw44I9606 rigid:H944ROEhiYqGZC5sqEqbxaKB65c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:Q9BPW8 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506836|imex:IM-28562-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606 rigid:0WyY0bY7+AdYt8WfgCMGekb1lvU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:Q8WXX5 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506829|imex:IM-28562-1125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 rigid:KbflEFHFatAcyquw/KV2o4zsi4U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36799 uniprotkb:Q15022 intact:EBI-7363822|intact:MINT-6732694|uniprotkb:Q81960 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:ve6_hpv03(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10614(hpv03)|taxid:10614(Human papillomavirus type 3) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506822|imex:IM-28562-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P36799|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xZxERJGHOtUDY8JjlbSF+uo927010614 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:LwE/Avj492J7qoV6/ZfDrbHLBek false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P04632 intact:EBI-7463272|intact:MINT-154028 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506815|imex:IM-28562-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:Yl6PExV3YVW9OQbOp04flkpVpXU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:O96000 intact:EBI-7463272|intact:MINT-154028 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506808|imex:IM-28562-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:l/KPttaJR8jrCp7qhE9ur0BQ26s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P00338 intact:EBI-7463272|intact:MINT-154028 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506801|imex:IM-28562-1123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 16"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 rigid:r4GupODls5iV/1E/+HCphXbGGD8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P11684 intact:EBI-7463272|intact:MINT-154028 intact:EBI-7797649|ensembl:ENSP00000278282|uniprotkb:Q9UCM4|uniprotkb:Q6FHH3|uniprotkb:Q9UCM2|uniprotkb:B2R5F2|intact:UNK-5371370|intact:MINT-8163275 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:uter_human(display_long)|uniprotkb:SCGB1A1(gene name)|psi-mi:SCGB1A1(display_short)|uniprotkb:CC10(gene name synonym)|uniprotkb:CCSP(gene name synonym)|uniprotkb:UGB(gene name synonym)|uniprotkb:Secretoglobin family 1A member 1(gene name synonym)|uniprotkb:Clara cell phospholipid-binding protein(gene name synonym)|uniprotkb:Clara cells 10 kDa secretory protein(gene name synonym)|uniprotkb:Urinary protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506794|imex:IM-28562-1121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0010193"(response to ozone)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0030141"(secretory granule)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0034097"(response to cytokine)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:0097160"(polychlorinated biphenyl binding)|interpro:IPR000329(Uteroglobin-like)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|interpro:IPR043215|mint:P11684|go:"GO:0009410"(response to xenobiotic stimulus)|ensembl:ENSG00000149021(gene)|ensembl:ENST00000278282(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007165"(signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0007566"(embryo implantation)|refseq:NP_003348.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA function:"Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2"|comment:mint figure legend:ST1|comment:"Y2H screens hits: 18"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:jYG+g4H4suclw2nro6YHdeV84jw9606 rigid:br0tRK0GwQWu4nU5VwD2Y5E3xag false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:Q14671 intact:EBI-7463272|intact:MINT-154028 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506787|imex:IM-28562-961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 19"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:2nIDJJ9ExUPSOp4lvD2gRoEr6MY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:O75414 intact:EBI-7463272|intact:MINT-154028 intact:EBI-3941531|uniprotkb:Q96E73|uniprotkb:B4DM99|uniprotkb:Q9BQ63|uniprotkb:B4DGW7|uniprotkb:Q53HM5|ensembl:ENSP00000392352|ensembl:ENSP00000399582|ensembl:ENSP00000406642|ensembl:ENSP00000440286|ensembl:ENSP00000495130 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ndk6_human(display_long)|uniprotkb:NME6(gene name)|psi-mi:NME6(display_short)|uniprotkb:Inhibitor of p53-induced apoptosis-alpha(gene name synonym)|uniprotkb:nm23-H6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506780|imex:IM-28562-763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001295355.1|refseq:NP_001295356.1|refseq:NP_001295357.1|refseq:NP_001295360.1|refseq:NP_001295362.1|refseq:NP_001295364.1|ensembl:ENST00000643457(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|ensembl:ENSG00000172113(gene)|interpro:IPR036850|interpro:IPR037994|ensembl:ENST00000415053(transcript)|ensembl:ENST00000426689(transcript)|ensembl:ENST00000442597(transcript)|ensembl:ENST00000452211(transcript)|refseq:NP_005784.1|refseq:XP_016861003.1|refseq:XP_016861004.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:m+HyqIFPTm9QBI2IwyvZ/kkJPhA9606 rigid:SeycAPqicNdwmfukJDrRdXPEfQI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P07339 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506773|imex:IM-28562-761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rigid:C9Rn1jQ7Wwdtha35GIkAFvCYAHw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:O75880 intact:EBI-7463272|intact:MINT-154028 intact:EBI-6656171|ensembl:ENSP00000255390|uniprotkb:B2RDM0 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sco1_human(display_long)|uniprotkb:SCO1(gene name)|psi-mi:SCO1(display_short)|uniprotkb:SCOD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506759|imex:IM-28562-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000133028(gene)|ensembl:ENST00000255390(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|rcsb pdb:1WP0|rcsb pdb:2GGT|rcsb pdb:2GQK|rcsb pdb:2GQL|rcsb pdb:2GQM|rcsb pdb:2GT5|rcsb pdb:2GT6|rcsb pdb:2GVP|rcsb pdb:2HRF|rcsb pdb:2HRN|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004580.1|dip:DIP-46086N|refseq:XP_005256808.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:oxGxX5mXuGDP5uPIW1vyOtaQHxU9606 rigid:0ij1+a1a04QIyaMXChyJN4+CQkU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P04406 intact:EBI-7463272|intact:MINT-154028 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506766|imex:IM-28562-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rigid:n3oF6SL+tFPelTx5/a/0J0YAzBE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:P21333 intact:EBI-26502480 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506983|imex:IM-28562-1137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:ST1|comment:"Y2H screens hits: 9"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 rigid:tTu4D8tNSni4NxWVhVpy+6lNygU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:O00515 intact:EBI-26502480 intact:EBI-2880585|ensembl:ENSP00000375829|uniprotkb:Q96GD8|uniprotkb:O95614 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:lad1_human(display_long)|uniprotkb:LAD1(gene name)|psi-mi:LAD1(display_short)|uniprotkb:LAD(gene name synonym)|uniprotkb:Linear IgA disease antigen(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507011|imex:IM-28562-771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENST00000391967(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017404(Ladinin 1)|mint:O00515|ensembl:ENSG00000159166(gene)|refseq:NP_005549.2 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:C58/NEfIlDj38lGEIsWtqBNuSis9606 rigid:2m97bfGEHhKXltnwi/lbWsbr7BE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:O75880 intact:EBI-26502480 intact:EBI-6656171|ensembl:ENSP00000255390|uniprotkb:B2RDM0 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sco1_human(display_long)|uniprotkb:SCO1(gene name)|psi-mi:SCO1(display_short)|uniprotkb:SCOD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507004|imex:IM-28562-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000133028(gene)|ensembl:ENST00000255390(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|rcsb pdb:1WP0|rcsb pdb:2GGT|rcsb pdb:2GQK|rcsb pdb:2GQL|rcsb pdb:2GQM|rcsb pdb:2GT5|rcsb pdb:2GT6|rcsb pdb:2GVP|rcsb pdb:2HRF|rcsb pdb:2HRN|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004580.1|dip:DIP-46086N|refseq:XP_005256808.1 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:oxGxX5mXuGDP5uPIW1vyOtaQHxU9606 rigid:NY3N+4MdPpeeGI9aqjfjSMp++5s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:P08962 intact:EBI-26502480 intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506997|imex:IM-28562-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome) - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606 rigid:eDr7zFHUyN27USygHMYwwHFQJ9c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:P04733 intact:EBI-26502480 intact:EBI-10209483|uniprotkb:Q9UI97|ensembl:ENSP00000334872 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mt1f_human(display_long)|uniprotkb:MT1F(gene name)|psi-mi:MT1F(display_short)|uniprotkb:Metallothionein-IF(gene name synonym)|uniprotkb:PRO0376(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506990|imex:IM-28562-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001288201.1|refseq:NP_005940.1|ensembl:ENSG00000198417(gene)|ensembl:ENST00000334350(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|reactome:R-HSA-5661231 - - - figure legend:ST1|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:gwJ22UrT1z8vNxqyRkEEzQ6Bhjg9606 rigid:UhCrBWAgwQ+u6PZbDSmQf1rpXgU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:Q14671 intact:EBI-26502480 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506976|imex:IM-28562-1135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST1|comment:"Y2H screens hits: 13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:plJ0QxdEJyE5/7iXBJlgzTGxpe0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q15365 intact:EBI-10917424 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506969|imex:IM-28562-1133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:ST1|comment:"Y2H screens hits: 20"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 rigid:AHjSbvPsLskmgh27z8yF08WggvQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:Q15434 intact:EBI-10917424 intact:EBI-721278|ensembl:ENSP00000262031 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rbms2_human(display_long)|uniprotkb:Suppressor of CDC2 with RNA-binding motif 3(gene name synonym)|uniprotkb:RBMS2(gene name)|psi-mi:RBMS2(display_short)|uniprotkb:SCR3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506962|imex:IM-28562-1265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002889.1|refseq:XP_011536942.1|refseq:XP_006719607.1|go:"GO:0005634"(nucleus)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|ensembl:ENSG00000076067(gene)|ensembl:ENST00000262031(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:1X4E - - - figure legend:ST1|comment:"Y2H screens hits: 12"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:Xp/0q4sekgC32j5HNpSoZZq/Idg9606 rigid:scgc9FEOlH71o7CiS3Ci6KvFlm4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:P84022 intact:EBI-10917424 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506955|imex:IM-28562-969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - - - figure legend:ST1|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:4Uij4Tjy2IRKpAl7e0r9kULyWKI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:P18283 intact:EBI-10917424 intact:EBI-3909751|ensembl:ENSP00000374265|uniprotkb:Q8WWI7|uniprotkb:Q6PJ52|uniprotkb:Q9NRP9 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:gpx2_human(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Gastrointestinal glutathione peroxidase(gene name synonym)|uniprotkb:Glutathione peroxidase-gastrointestinal(gene name synonym)|uniprotkb:Glutathione peroxidase-related protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506948|imex:IM-28562-769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000176153(gene)|ensembl:ENST00000389614(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009055"(electron transfer activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|rcsb pdb:2HE3|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-3299685|reactome:R-HSA-5628897|refseq:NP_002074.2 - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:CnzeIDDze+0YRNX1ktua2yIV+Mw9606 rigid:GQxLumhlaGGmva1364gBscEkaTQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:P00156 intact:EBI-10917424 intact:EBI-1224441|uniprotkb:Q34786|uniprotkb:Q8HBR6|uniprotkb:Q8HNQ0|uniprotkb:Q8HNQ1|uniprotkb:Q8HNQ9|uniprotkb:Q8HNR4|uniprotkb:Q8HNR7|uniprotkb:Q8W7V8|uniprotkb:Q8WCV9|uniprotkb:Q8WCY2|uniprotkb:Q8WCY7|uniprotkb:Q8WCY8|uniprotkb:Q9B1A6|uniprotkb:Q9B1B6|uniprotkb:Q9B1B8|uniprotkb:Q9B1D4|uniprotkb:Q9B1X6|uniprotkb:Q9B2V0|uniprotkb:Q9B2V8|uniprotkb:Q9B2W0|uniprotkb:Q9B2W3|uniprotkb:Q9B2W8|uniprotkb:Q9B2X1|uniprotkb:Q9B2X7|uniprotkb:Q9B2X9|uniprotkb:Q9B2Y3|uniprotkb:Q9B2Z0|uniprotkb:Q9B2Z4|uniprotkb:Q9T6H6|uniprotkb:Q9T9Y0|uniprotkb:Q9TEH4|ensembl:ENSP00000354554 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cyb_human(display_long)|uniprotkb:MT-CYB(gene name)|psi-mi:MT-CYB(display_short)|uniprotkb:COB(gene name synonym)|uniprotkb:CYTB(gene name synonym)|uniprotkb:MTCYB(gene name synonym)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome b subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 3(gene name synonym)|uniprotkb:Complex III subunit 3(gene name synonym)|uniprotkb:Complex III subunit III(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506941|imex:IM-28562-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:YP_003024038.1|ensembl:ENSG00000198727(gene)|ensembl:ENST00000361789(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009408"(response to heat)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033590"(response to cobalamin)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR005798(Cytochrome b/b6, C-terminal)|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027387|interpro:IPR030689|interpro:IPR036150|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:pmuj0KISx06AK4PF7DVEwDVsV9M9606 rigid:8J+KgNzVDQQzJDOdvJ8cy6SRIZ4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:P53992 intact:EBI-10917424 intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506934|imex:IM-28562-967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606 rigid:iV7XYRqeTr83aC+RXW+8E7bPvuo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06930 uniprotkb:O75528 intact:EBI-10917424 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:ve6_hpv05(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333923(hpv05)|taxid:333923(hpv05) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506927|imex:IM-28562-1131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041365.1|interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:CaZnCXpSQL+vrA/weLPllGHKlsc333923 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:XzRR1t4ImM41fW2REE4vbMYYxJk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:Q66K74 intact:EBI-7463272|intact:MINT-154028 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506752|imex:IM-28562-1263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:nqy0Qzopmybvh7kv8Jzs5e2IpnY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:Q9Y244 intact:EBI-7463272|intact:MINT-154028 intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506745|imex:IM-28562-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606 rigid:wKhWIrInrqWRLi5TBVYC+A9rEVU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P04733 intact:EBI-7463272|intact:MINT-154028 intact:EBI-10209483|uniprotkb:Q9UI97|ensembl:ENSP00000334872 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mt1f_human(display_long)|uniprotkb:MT1F(gene name)|psi-mi:MT1F(display_short)|uniprotkb:Metallothionein-IF(gene name synonym)|uniprotkb:PRO0376(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506738|imex:IM-28562-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001288201.1|refseq:NP_005940.1|ensembl:ENSG00000198417(gene)|ensembl:ENST00000334350(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|reactome:R-HSA-5661231 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:gwJ22UrT1z8vNxqyRkEEzQ6Bhjg9606 rigid:Jx4DeAHxItJ1Sa677jJsL2fCGFg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P06733 intact:EBI-7463272|intact:MINT-154028 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506731|imex:IM-28562-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:fiYOo4purfNopG33V9UEUXGeRcg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06929 uniprotkb:P36507 intact:EBI-7463272|intact:MINT-154028 intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042 psi-mi:ve6_hpv1(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26506724|imex:IM-28562-1261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|refseq:NP_040305.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:z4tAJ332ObSFz1gXKm2+1l3YG8I10583 rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606 rigid:DWBIouIio7711drI/fam7uVTTYU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P62891 intact:EBI-7463243|intact:MINT-154050 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507053|imex:IM-28562-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 rigid:OcUsRHwQud8zqmqfb+HUsMYTuN4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P08865 intact:EBI-7463243|intact:MINT-154050 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507046|imex:IM-28562-775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 rigid:AlxuA21YGi9Q2EwLaxXQKhkZxNo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P05388 intact:EBI-7463243|intact:MINT-154050 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507039|imex:IM-28562-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 rigid:hepjbKET7M9zE0estCXr6YJ1Th0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00403 uniprotkb:P06428 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-7463243|intact:MINT-154050 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507032|imex:IM-28562-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 - - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA figure legend:ST1|comment:"Y2H screens hits: 13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rigid:0ezOVEZpS50qp4OpOwCQ3f4zxCM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:Q9BRJ6 intact:EBI-26502480 intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507025|imex:IM-28562-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding) - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606 rigid:G60161p8tXS0CBFZUnkZlCMvxzE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84291 uniprotkb:Q86X02 intact:EBI-26502480 intact:EBI-11063830|uniprotkb:Q15175|uniprotkb:B4DFA7|ensembl:ENSP00000336587 psi-mi:ve6_hpv6a(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cdr2l_human(display_long)|uniprotkb:CDR2L(gene name)|psi-mi:CDR2L(display_short)|uniprotkb:HUMPPA(gene name synonym)|uniprotkb:Paraneoplastic 62 kDa antigen(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507018|imex:IM-28562-773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_055418.2|ensembl:ENSG00000109089(gene)|ensembl:ENST00000337231(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR026079 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:LABxTIy7U3uSvBRKUxPWUif0s5k37122 rogid:ngogDRfXQxNsgTotqk2KfTdkUFA9606 rigid:MxWsLqkO5CMLF19aG0ewa40cPag false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P15954 intact:EBI-7463243|intact:MINT-154050 intact:EBI-2606678|uniprotkb:Q6NR81|ensembl:ENSP00000247655|ensembl:ENSP00000425759 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cox7c_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VIIc(gene name synonym)|uniprotkb:COX7C(gene name)|psi-mi:COX7C(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507176|imex:IM-28562-973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001858.1|ensembl:ENST00000247655(transcript)|ensembl:ENST00000509578(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004202(Cytochrome c oxidase subunit VIIc)|interpro:IPR036636|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000127184(gene) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:hBYR7f5I8aE5H8JreIvHF8tg1HU9606 rigid:yaGjHvulCdVA0LmksVPyK4kcn+0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P30408 intact:EBI-7463243|intact:MINT-154050 intact:EBI-714256|uniprotkb:Q6IB51|ensembl:ENSP00000304277 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:t4s1_human(display_long)|uniprotkb:Tumor-associated antigen L6(gene name synonym)|uniprotkb:Membrane component chromosome 3 surface marker 1(gene name synonym)|uniprotkb:TM4SF1(gene name)|psi-mi:TM4SF1(display_short)|uniprotkb:TAAL6(gene name synonym)|uniprotkb:M3S1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507169|imex:IM-28562-1281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_055035.1|ensembl:ENSG00000169908(gene)|ensembl:ENST00000305366(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008661(L6 membrane) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:8bUJ4R8pfga0mbUtwmz4KGnEUH09606 rigid:iiUmE/QluaKsgHAN4h1pTIOL+Aw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P40429 intact:EBI-7463243|intact:MINT-154050 intact:EBI-720205|uniprotkb:A8K505|ensembl:ENSP00000375730 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl13a_human(display_long)|uniprotkb:23 kDa highly basic protein(gene name synonym)|uniprotkb:RPL13A(gene name)|psi-mi:RPL13A(display_short)|uniprotkb:Large ribosomal subunit protein uL13(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507162|imex:IM-28562-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_036555.1|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6OLF|ensembl:ENSG00000142541(gene)|ensembl:ENST00000391857(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P40429|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|refseq:NP_001257420.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:pcKDTEBZXxtm1MAH+4nv0p3PqFs9606 rigid:A26L3WoEA1qzTj4CkMb1I6ZHYfs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P26641 intact:EBI-7463243|intact:MINT-154050 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507155|imex:IM-28562-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 rigid:S672/9RC/IeRRZpl0tV0PC/QxTE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P00156 intact:EBI-7463243|intact:MINT-154050 intact:EBI-1224441|uniprotkb:Q34786|uniprotkb:Q8HBR6|uniprotkb:Q8HNQ0|uniprotkb:Q8HNQ1|uniprotkb:Q8HNQ9|uniprotkb:Q8HNR4|uniprotkb:Q8HNR7|uniprotkb:Q8W7V8|uniprotkb:Q8WCV9|uniprotkb:Q8WCY2|uniprotkb:Q8WCY7|uniprotkb:Q8WCY8|uniprotkb:Q9B1A6|uniprotkb:Q9B1B6|uniprotkb:Q9B1B8|uniprotkb:Q9B1D4|uniprotkb:Q9B1X6|uniprotkb:Q9B2V0|uniprotkb:Q9B2V8|uniprotkb:Q9B2W0|uniprotkb:Q9B2W3|uniprotkb:Q9B2W8|uniprotkb:Q9B2X1|uniprotkb:Q9B2X7|uniprotkb:Q9B2X9|uniprotkb:Q9B2Y3|uniprotkb:Q9B2Z0|uniprotkb:Q9B2Z4|uniprotkb:Q9T6H6|uniprotkb:Q9T9Y0|uniprotkb:Q9TEH4|ensembl:ENSP00000354554 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cyb_human(display_long)|uniprotkb:MT-CYB(gene name)|psi-mi:MT-CYB(display_short)|uniprotkb:COB(gene name synonym)|uniprotkb:CYTB(gene name synonym)|uniprotkb:MTCYB(gene name synonym)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome b subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 3(gene name synonym)|uniprotkb:Complex III subunit 3(gene name synonym)|uniprotkb:Complex III subunit III(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507148|imex:IM-28562-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:YP_003024038.1|ensembl:ENSG00000198727(gene)|ensembl:ENST00000361789(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009408"(response to heat)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033590"(response to cobalamin)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR005798(Cytochrome b/b6, C-terminal)|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027387|interpro:IPR030689|interpro:IPR036150|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:pmuj0KISx06AK4PF7DVEwDVsV9M9606 rigid:utlAoNUlDwCeIKoCVf6XYrQKZjg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P07355 intact:EBI-7463243|intact:MINT-154050 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507141|imex:IM-28562-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:3kmhZ8zyJA6K8Z1nNgx4ZKlwOt8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P05787 intact:EBI-7463243|intact:MINT-154050 intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|ensembl:ENSP00000293308|ensembl:ENSP00000447402|ensembl:ENSP00000447566|uniprotkb:A8K4H3|uniprotkb:B0AZN5|uniprotkb:F8VXB4 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507134|imex:IM-28562-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001243222.1|ensembl:ENSG00000170421(gene)|ensembl:ENST00000293308(transcript)|ensembl:ENST00000546897(transcript)|ensembl:ENST00000552551(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:zyV8eOjx426ehjJYK4jsizORUws9606 rigid:AX9tsLaOP0+a46gVW7NfnMhAbd4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P83731 intact:EBI-7463243|intact:MINT-154050 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507127|imex:IM-28562-971 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 rigid:7bDCO+70Lzf+WJjaAcvBm+5897A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P27635 intact:EBI-7463243|intact:MINT-154050 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507120|imex:IM-28562-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 rigid:l+hUOEDeoLm4MlGxxcfrHr0JU+M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06428 uniprotkb:P13646 intact:EBI-7463243|intact:MINT-154050 intact:EBI-1223876|uniprotkb:Q53G54|uniprotkb:Q6AZK5|uniprotkb:Q8N240|ensembl:ENSP00000246635 psi-mi:ve6_hpv08(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:k1c13_human(display_long)|uniprotkb:KRT13(gene name)|psi-mi:KRT13(display_short)|uniprotkb:Keratin-13(gene name synonym)|uniprotkb:Cytokeratin-13(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10579(hpv08)|taxid:10579(Human papillomavirus type 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507113|imex:IM-28562-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002265.2|refseq:NP_705694.2|ensembl:ENSG00000171401(gene)|ensembl:ENST00000246635(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - comment:mint|function:Transcriptional transactivator. Binds double stranded DNA - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:eY0ilaC5gZCmCNtwwy9GhcgFUw010579 rogid:u65zix/f6VQ+vmbfMhXWqmiERRY9606 rigid:AyWjdjVcliNfomrzexwinyMoG28 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:P02792 intact:EBI-1186926 intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507302|imex:IM-28562-1289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606 rigid:n+iYmqKnfkfiGqAlWPd2SwD3b14 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:Q66K74 intact:EBI-1186926 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507295|imex:IM-28562-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:PTRi7i4h0BLM5VN0zSfiZqN5wEY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:Q92530 intact:EBI-1186926 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507288|imex:IM-28562-1143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:ST1|comment:"Y2H screens hits: 14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 rigid:jzEipnY7xxgw+20kP34UIxW/wI8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24835 uniprotkb:Q92597 intact:EBI-11793707 intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977|ensembl:ENSP00000404854 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507456|imex:IM-28562-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001128714.1|refseq:NP_006087.2|refseq:NP_001245361.1|refseq:NP_001245362.1|ensembl:ENSG00000104419(gene)|ensembl:ENST00000323851(transcript)|ensembl:ENST00000414097(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010038"(response to metal ion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045576"(mast cell activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030693|rcsb pdb:6ZMM|reactome:R-HSA-6803205 - - - figure legend:ST1|comment:"Y2H screens hits: 15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606 rigid:asQsVwwUlmFfBGjitAPGDvZO4Hg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:Q9UQ26 intact:EBI-11737184 intact:EBI-1756749|uniprotkb:O43413|uniprotkb:Q86XL9|uniprotkb:Q8IWV9|uniprotkb:Q8IWW1|uniprotkb:B3KX91|uniprotkb:F8WD47|intact:EBI-28973118 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rims2_human(display_long)|uniprotkb:RIMS2(gene name)|psi-mi:RIMS2(display_short)|uniprotkb:KIAA0751(gene name synonym)|uniprotkb:RAB3IP3(gene name synonym)|uniprotkb:RIM2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)|uniprotkb:Rab-3-interacting protein 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507449|imex:IM-28562-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001269810.1|refseq:NP_001269811.1|ensembl:ENST00000262231|ensembl:ENSP00000262231|ensembl:ENSG00000176406|ensembl:ENST00000339750|ensembl:ENSP00000342051|ensembl:ENSP00000427018|ensembl:ENST00000507740|ensembl:ENSP00000423559|ensembl:ENST00000504942|refseq:NP_001093587.1|refseq:NP_055492.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|rcsb pdb:1V27|rcsb pdb:1WFG|interpro:IPR039032|interpro:IPR030631|interpro:IPR035892|interpro:IPR036034|interpro:IPR041282|interpro:IPR041489|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential) - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:r+m/eB+6yczGhwv4pxI6vzG/RHc9606 rigid:6FFFnL0PyHMoPfHLsrQm0y6hR1Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:P04406 intact:EBI-11737184 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507442|imex:IM-28562-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rigid:ehdNQByzOWGHxL97bmmCaK37C8U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:O96000 intact:EBI-11737184 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507435|imex:IM-28562-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:Es7PxqUFQKIoOGB7o2Mo4LtFl/4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:Q14671 intact:EBI-11737184 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507428|imex:IM-28562-787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:fwIbslOVdXDR2REa4A9r+71ufOw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:Q9BPW8 intact:EBI-11737184 intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507421|imex:IM-28562-1145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606 rigid:kuyfRLndNki9jHYxE9JUcloPuME false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:Q9NQ31 intact:EBI-11737184 intact:EBI-517035|uniprotkb:Q8NBS2|uniprotkb:Q8TAC6|uniprotkb:Q8TAD3|uniprotkb:Q8TAE0|ensembl:ENSP00000310459|ensembl:ENSP00000431331 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:akip1_human(display_long)|uniprotkb:Breast cancer-associated gene 3 protein(gene name synonym)|uniprotkb:PKA-interacting protein(gene name synonym)|uniprotkb:AKIP1(gene name)|psi-mi:AKIP1(display_short)|uniprotkb:BCA3(gene name synonym)|uniprotkb:C11orf17(gene name synonym)|uniprotkb:Proline-rich protein BCA3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507414|imex:IM-28562-785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001193575.1|refseq:NP_001193576.1|refseq:NP_001193577.1|refseq:NP_065693.2|refseq:XP_016873500.1|ensembl:ENSG00000166452(gene)|ensembl:ENST00000309377(transcript)|ensembl:ENST00000534147(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR033214 - - - figure legend:ST1|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:EdMopChLAM1kUZUfo5Z9IBU0Vyg9606 rigid:1LWyIO9rm1Ad9jIbImRq2/+1Rdk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:Q9BUB7 intact:EBI-11737184 intact:EBI-726363|uniprotkb:Q9NWY5|uniprotkb:E9PDY9|ensembl:ENSP00000312599 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:tmm70_human(display_long)|uniprotkb:TMEM70(gene name)|psi-mi:TMEM70(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507407|imex:IM-28562-783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001035703.1|refseq:NP_060336.3|ensembl:ENSG00000175606(gene)|ensembl:ENST00000312184(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR009724(Protein of unknown function DUF1301)|mint:Q9BUB7|go:"GO:0005743"(mitochondrial inner membrane) - - - figure legend:ST1|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:6LHWSQP2W1CRBgylWi8Ncc3X/3E9606 rigid:11IdmmXq3KrX3J+WqetgoxwmnjI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:Q9Y3D0 intact:EBI-11737184 intact:EBI-744045|ensembl:ENSP00000387471 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507400|imex:IM-28562-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830 - - - figure legend:ST1|comment:"Y2H screens hits: 13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606 rigid:VwOkHqF6y21BpaPrrD8nDYeNAnM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06427 uniprotkb:P22234 intact:EBI-11737184 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:ve6_hpv33(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507393|imex:IM-28562-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:ST1|comment:"Y2H screens hits: 16"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Y810RF3mVPC0nYIP1S+ugQnCNo410586 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:e/MG2NCvwlrjzglF7NYjTcLXXFU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36810 uniprotkb:P84077 intact:EBI-26503648 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507386|imex:IM-28562-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:RRXi5UySIrijN1DxXc6EyXyVe9k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36810 uniprotkb:Q66K74 intact:EBI-26503648 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507379|imex:IM-28562-781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:TE0seYKZ8cAwFzvWYKrsKO1ywao false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NDL9 uniprotkb:P36810 intact:EBI-7962937|uniprotkb:Q9H8P8|uniprotkb:Q9H6V0|uniprotkb:Q96IK8|uniprotkb:B7Z7I7|uniprotkb:Q53SZ0|uniprotkb:Q53SW0|uniprotkb:B7WPG9|intact:MINT-4717805|uniprotkb:A2VDI7|uniprotkb:D6W548|ensembl:ENSP00000353249 intact:EBI-26503648 psi-mi:cbpc5_human(display_long)|uniprotkb:Protein deglutamylase CCP5(gene name synonym)|uniprotkb:AGBL5(gene name)|psi-mi:AGBL5(display_short)|uniprotkb:CCP5(gene name synonym)|uniprotkb:ATP/GTP-binding protein-like 5(gene name synonym) psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507372|imex:IM-28562-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011531313.1|refseq:XP_011531314.1|refseq:XP_011531315.1|refseq:NP_001030584.1|refseq:NP_068603.4|ensembl:ENSG00000084693(gene)|ensembl:ENST00000360131(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0030496"(midbody)|go:"GO:0035608"(protein deglutamylation)|go:"GO:0035611"(protein branching point deglutamylation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051607"(defense response to virus)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR034286|interpro:IPR040626|mint:Q8NDL9|reactome:R-HSA-8955332 go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 - comment:mint - figure legend:ST1|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:ymXCvYKmtqHnaafXZoynEJhVt9M9606 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rigid:LGZclfBGHv+cNbjQ3bkzHPoYOEg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36810 uniprotkb:P50995 intact:EBI-26503648 intact:EBI-715243|ensembl:ENSP00000361305|ensembl:ENSP00000398610|ensembl:ENSP00000404412|uniprotkb:B4DVE7|intact:EBI-10981770 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:anx11_human(display_long)|uniprotkb:Annexin-11(gene name synonym)|uniprotkb:Annexin XI(gene name synonym)|uniprotkb:Calcyclin-associated annexin 50(gene name synonym)|uniprotkb:56 kDa autoantigen(gene name synonym)|uniprotkb:ANXA11(gene name)|psi-mi:ANXA11(display_short)|uniprotkb:ANX11(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507365|imex:IM-28562-777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 ensembl:ENSG00000122359(gene)|ensembl:ENST00000372231(transcript)|ensembl:ENST00000422982(transcript)|ensembl:ENST00000438331(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030496"(midbody)|go:"GO:0032506"(cytokinetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR008157(Annexin, type XI, N-terminal)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|refseq:NP_001148.1|refseq:NP_665875.1|refseq:NP_665876.1|refseq:XP_011538038.1|refseq:NP_001265336.1|refseq:NP_001265337.1|refseq:NP_001265338.1 - - - figure legend:ST1|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:6j7B4/J0DI0LZADQ5klJQoYf7289606 rigid:Rs9r8t0NaozNtcp7phYNgPsNkvg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36810 uniprotkb:Q496F6 intact:EBI-26503648 intact:EBI-18010148|uniprotkb:B4DNS1|uniprotkb:Q7Z7I3|ensembl:ENSP00000376395 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:clm2_human(display_long)|uniprotkb:CD300 antigen-like family member E(gene name synonym)|uniprotkb:CMRF35-A5(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 2(gene name synonym)|uniprotkb:Polymeric immunoglobulin receptor 2(gene name synonym)|uniprotkb:CD300E(gene name)|psi-mi:CD300E(display_short)|uniprotkb:CD300LE(gene name synonym)|uniprotkb:CLM2(gene name synonym)|uniprotkb:CMRF35A5(gene name synonym)|uniprotkb:IREM2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507358|imex:IM-28562-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_852114.2|ensembl:ENSG00000186407(gene)|ensembl:ENST00000392619(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:ST1|comment:"Y2H screens hits: 9"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:tmruU+BuI41lXctw0ZHhYSs7e209606 rigid:eDmNrko8a2sVJ3E/VRprflqeGYU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36810 uniprotkb:P36404 intact:EBI-26503648 intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021 psi-mi:ve6_hpv32(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507351|imex:IM-28562-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|refseq:NP_041801.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002 - - - figure legend:ST1|comment:"Y2H screens hits: 37"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Tdo3NXUa18/cpxoYmHkNbXiYOtU333763 rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606 rigid:ZFpXtXUDOxXRFhFCrdOyzfuny3o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:Q7Z6J9 intact:EBI-1186926 intact:EBI-2559824|uniprotkb:Q8N9H2|uniprotkb:Q86WV3|uniprotkb:Q86XE4|ensembl:ENSP00000327487 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:sen54_human(display_long)|uniprotkb:TSEN54(gene name)|psi-mi:TSEN54(display_short)|uniprotkb:SEN54 homolog(gene name synonym)|uniprotkb:SEN54(gene name synonym)|uniprotkb:tRNA-intron endonuclease Sen54(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507344|imex:IM-28562-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_997229.2|ensembl:ENSG00000182173(gene)|ensembl:ENST00000333213(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006397"(mRNA processing)|interpro:IPR024336|interpro:IPR024337|reactome:R-HSA-6784531 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:X/pxgeNwOhUu889Z4BvgrECLQMM9606 rigid:hRPZhdLPwMqj/aNoQgcROtlTwbo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BY07 uniprotkb:P06463 intact:EBI-7642622|ensembl:ENSP00000251768|ensembl:ENSP00000366861|uniprotkb:Q32MA7|intact:MINT-6489517|uniprotkb:Q8WXD7|uniprotkb:Q59EQ9|uniprotkb:Q9HBU5|uniprotkb:Q96DS8|uniprotkb:Q8WXD3|uniprotkb:Q96DS7 intact:EBI-1186926 psi-mi:s4a5_human(display_long)|uniprotkb:SLC4A5(gene name)|psi-mi:SLC4A5(display_short)|uniprotkb:NBC4(gene name synonym)|uniprotkb:Solute carrier family 4 member 5(gene name synonym)|uniprotkb:NBCe2(gene name synonym) psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507337|imex:IM-28562-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188687(gene)|ensembl:ENST00000346834(transcript)|ensembl:ENST00000377634(transcript)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003014"(renal system process)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008510"("sodium:bicarbonate symporter activity")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR003024(Sodium bicarbonate cotransporter)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|mint:Q9BY07|reactome:R-HSA-425381|refseq:NP_067019.3|refseq:NP_597812.1 refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N - function:"Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH"|comment:mint - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1rlRAY4QuFB69UyndCVWQ8xMGdE9606 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rigid:DRrF4QlNWCgFdg7tTQaiZrMExzQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:Q13950 intact:EBI-1186926 intact:EBI-976402|intact:EBI-28971669|ensembl:ENSP00000360493|ensembl:ENSP00000495497|uniprotkb:O14614|uniprotkb:O14615|uniprotkb:O95181 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:runx2_human(display_long)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:RUNX2(gene name)|psi-mi:RUNX2(display_short)|uniprotkb:AML3(gene name synonym)|uniprotkb:CBFA1(gene name synonym)|uniprotkb:OSF2(gene name synonym)|uniprotkb:PEBP2A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507330|imex:IM-28562-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N ensembl:ENST00000359524|ensembl:ENSP00000352514|ensembl:ENST00000371432|ensembl:ENSP00000360486|ensembl:ENST00000371436|ensembl:ENSP00000360491|ensembl:ENSP00000360493|ensembl:ENSP00000495497|ensembl:ENSG00000124813(gene)|ensembl:ENST00000371438(transcript)|ensembl:ENST00000647337(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|interpro:IPR027384|mint:Q13950|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0043425"(bHLH transcription factor binding)|rcsb pdb:6VG8|rcsb pdb:6VGD|rcsb pdb:6VGE|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|rcsb pdb:6VGG|reactome:R-HSA-2032785|reactome:R-HSA-8878166|reactome:R-HSA-8939246|reactome:R-HSA-8939902|reactome:R-HSA-8940973|reactome:R-HSA-8941284|reactome:R-HSA-8941326|reactome:R-HSA-8941332|reactome:R-HSA-8941333|refseq:NP_001015051.3|refseq:NP_001019801.3|dip:DIP-36707N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:aUhn8jpJsl5oS4kMBgUYdpncy6Y9606 rigid:OLTbuiTMiUD9BTUs1psfPNHByqk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P35250 uniprotkb:P06463 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 intact:EBI-1186926 psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507323|imex:IM-28562-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rigid:Gu2cxVl/LdrdxeCBWEhdmt+oMi4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:O96000 intact:EBI-1186926 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507316|imex:IM-28562-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:fLQ6ntYj/xwF0t4Ch0iC6CYtAVw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:P06733 intact:EBI-1186926 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507309|imex:IM-28562-987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:hcJscJV7CbFSCOkwigcPIn8Itow false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06463 uniprotkb:Q92597 intact:EBI-1186926 intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977|ensembl:ENSP00000404854 psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507281|imex:IM-28562-1141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N refseq:NP_001128714.1|refseq:NP_006087.2|refseq:NP_001245361.1|refseq:NP_001245362.1|ensembl:ENSG00000104419(gene)|ensembl:ENST00000323851(transcript)|ensembl:ENST00000414097(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010038"(response to metal ion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045576"(mast cell activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030693|rcsb pdb:6ZMM|reactome:R-HSA-6803205 - - - figure legend:ST1|comment:"Y2H screens hits: 19"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606 rigid:Fz2fH4FFNRi8XL23khHcjwgGW3g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03126 uniprotkb:P36507 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507274|imex:IM-28562-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606 rigid:oebmPeqRRjOU9ogf8VEiQ82e6pM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03126 uniprotkb:O43166 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507267|imex:IM-28562-985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361 - - - figure legend:ST1|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606 rigid:idqtYxh+0ya/x+gtxHKgppzJghc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03126 uniprotkb:Q9Y3D0 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-744045|ensembl:ENSP00000387471 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507260|imex:IM-28562-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830 - - - figure legend:ST1|comment:"Y2H screens hits: 13"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606 rigid:0StLuk6H0t6tS2FOD10DE8GLM0s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03126 uniprotkb:Q13485 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507253|imex:IM-28562-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N - - - figure legend:ST1|comment:"Y2H screens hits: 18"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:mPu190hmySGV54KAtldys/IHuo89606 rigid:SBp7Y7pPjYSswQoxCSEGSsBAV2M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03126 uniprotkb:Q8IZ96 intact:EBI-1177242|uniprotkb:Q71BI7 intact:EBI-20721283|ensembl:ENSP00000405729|intact:EBI-28985356|uniprotkb:Q2PPY5|uniprotkb:Q6PEV5|uniprotkb:Q8IU76|uniprotkb:Q8IU83|uniprotkb:Q8IU86|uniprotkb:Q8IU93|uniprotkb:Q8IZ87|uniprotkb:Q8IZ88|uniprotkb:Q8IZ89|uniprotkb:Q8IZ90|uniprotkb:Q8IZ91|uniprotkb:Q8IZ92|uniprotkb:Q8IZ93|uniprotkb:Q8IZ94|uniprotkb:Q8IZ95|uniprotkb:Q96JC2|uniprotkb:Q96JC3 psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:cklf1_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 1(gene name synonym)|uniprotkb:CMTM1(gene name)|psi-mi:CMTM1(display_short)|uniprotkb:CKLFSF1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507246|imex:IM-28562-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N ensembl:ENST00000332695|ensembl:ENSP00000331428|ensembl:ENST00000333001|ensembl:ENSP00000331494|ensembl:ENST00000336328|ensembl:ENSP00000337119|ensembl:ENST00000379500|ensembl:ENSP00000368814|ensembl:ENSP00000405729|ensembl:ENST00000528324|ensembl:ENSP00000432398|ensembl:ENST00000528484|ensembl:ENSP00000437079|ensembl:ENSP00000431303|ensembl:ENST00000531885|ensembl:ENSP00000432687|ensembl:ENST00000533078|ensembl:ENSP00000432387|ensembl:ENST00000533666|ensembl:ENSP00000435020|ensembl:ENST00000533915|ensembl:ENSP00000435755|ensembl:ENST00000529386|ensembl:ENSG00000089505(gene)|ensembl:ENST00000457188(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008253(Marvel)|refseq:NP_443725.3|refseq:NP_851785.2|refseq:NP_851786.1|refseq:NP_851787.1|refseq:NP_851788.1|refseq:NP_851789.1|refseq:NP_851800.1|refseq:NP_851813.1 - - - figure legend:ST1|comment:"Y2H screens hits: 22"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760 rogid:yRl8CqhJza5ceChn0YnuyPbBFJc9606 rigid:cxNNsiIWDT9toah8tBAO26pbl3k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:P84022 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507239|imex:IM-28562-983 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - - - figure legend:ST1|comment:"Y2H screens hits: 54"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:lLBFj05sKk4NYuVmaSijktGKfPI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:Q15796 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507232|imex:IM-28562-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N - - - figure legend:ST1|comment:"Y2H screens hits: 9"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:oxsHnr3tejMp0HYIE2MVkIhm010 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:P23396 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507225|imex:IM-28562-1287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 rigid:5dLf5k4/LEtB/o4t41dVHAi7OYs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:P36952 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-2371394|uniprotkb:B2R6Y4|uniprotkb:Q6N0B4|uniprotkb:Q8WW89|ensembl:ENSP00000372221 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:spb5_human(display_long)|uniprotkb:SERPINB5(gene name)|psi-mi:SERPINB5(display_short)|uniprotkb:PI5(gene name synonym)|uniprotkb:Peptidase inhibitor 5(gene name synonym)|uniprotkb:Maspin(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507218|imex:IM-28562-975 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_002630.2|ensembl:ENSG00000206075(gene)|ensembl:ENST00000382771(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0060512"(prostate gland morphogenesis)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000240(Serpin B9 and maspin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033836|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P36952|rcsb pdb:1WZ9|rcsb pdb:1XQG|rcsb pdb:1XQJ|rcsb pdb:1XU8 - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:p2g5mTsqtSjgS73Zvoy64BV5Zes9606 rigid:LMlf4HirgG5zt3hzxW4lFYeti6Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:Q5TAQ9 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-740686|uniprotkb:Q12839|uniprotkb:Q4QQI6|uniprotkb:Q53F14|uniprotkb:Q66K50|uniprotkb:Q68CS7|uniprotkb:Q96E00|intact:EBI-2559125|uniprotkb:D3DVE6|ensembl:ENSP00000318227|ensembl:ENSP00000357052|ensembl:ENSP00000357053 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:dcaf8_human(display_long)|uniprotkb:DCAF8(gene name)|psi-mi:DCAF8(display_short)|uniprotkb:H326(gene name synonym)|uniprotkb:WDR42A(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507211|imex:IM-28562-1285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_056541.2|ensembl:ENSG00000132716(gene)|ensembl:ENST00000326837(transcript)|ensembl:ENST00000368073(transcript)|ensembl:ENST00000368074(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q5TAQ9|rcsb pdb:3I8E|reactome:R-HSA-8951664|dip:DIP-48762N - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:6Bbv6KwtHrJ0W4mcIronVPj4bTA9606 rigid:wnzdWd5UzX/DvGA23bPCWhIiV8g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00403 uniprotkb:P36801 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-26502745|uniprotkb:Q81988 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507204|imex:IM-28562-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 - - - figure legend:ST1|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rigid:TncJqymTrqCHGdE7FWULyREOUCM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:Q9BQA1 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507197|imex:IM-28562-1283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:XwSZxKNPYO1HvEMndeFCW8SqYyo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:P08865 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507190|imex:IM-28562-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:ST1|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 rigid:bksU74CkqbhrCIFHLPsH1RUbJMs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36801 uniprotkb:P02792 intact:EBI-26502745|uniprotkb:Q81988 intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0 psi-mi:ve6_hpv09(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507183|imex:IM-28562-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041860.1|refseq:NP_041861.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575 refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:kIHguw/1+xBiUwUFGjCljMRI0LQ10621 rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606 rigid:+wqfM3GHhsqnVFnrHTI7UWTucsk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:P12272 intact:EBI-1776887 intact:EBI-2372758|uniprotkb:Q15251|uniprotkb:Q6FH74|ensembl:ENSP00000379213|ensembl:ENSP00000441571|ensembl:ENSP00000441765 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pthr_human(display_long)|uniprotkb:PTHLH(gene name)|psi-mi:PTHLH(display_short)|uniprotkb:PTHRP(gene name synonym)|uniprotkb:Parathyroid hormone-like protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507652|imex:IM-28562-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:XP_011519076.1|refseq:XP_011519077.1|refseq:NP_002811.1|refseq:NP_945315.1|refseq:NP_945316.1|refseq:NP_945317.1|refseq:XP_016875163.1|refseq:XP_016875164.1|ensembl:ENSG00000087494(gene)|ensembl:ENST00000395872(transcript)|ensembl:ENST00000539239(transcript)|ensembl:ENST00000545234(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030282"(bone mineralization)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0061182"(negative regulation of chondrocyte development)|interpro:IPR001415(Parathyroid hormone)|interpro:IPR003626(Parathyroid hormone-related protein)|rcsb pdb:1BZG|rcsb pdb:1ET3|rcsb pdb:1M5N|rcsb pdb:3FFD|rcsb pdb:3H3G|reactome:R-HSA-373080|reactome:R-HSA-418555|reactome:R-HSA-9660821 - - - figure legend:ST2|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:xDgieq0IrFJamEASMichGJUQFbg9606 rigid:pCc1rNkp8D4T4RGcTjC0ZnojAbc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:Q8IZC6 intact:EBI-1776887 intact:EBI-2529384|uniprotkb:Q66K43|uniprotkb:Q96JF7|ensembl:ENSP00000348385 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cora1_human(display_long)|uniprotkb:COL27A1(gene name)|psi-mi:COL27A1(display_short)|uniprotkb:KIAA1870(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507645|imex:IM-28562-797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000196739(gene)|ensembl:ENST00000356083(transcript)|go:"GO:0003431"(growth plate cartilage chondrocyte development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005583"(fibrillar collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_116277.2 - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:+Hwz0vac4YiN3eiJr0WxgHuQsiM9606 rigid:lSoplsFjzvbAv6EPq0mzmut5mXY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:O94885 intact:EBI-1776887 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507638|imex:IM-28562-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:vVOT37nwPqx+lBd/6eZtvE6ts8U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:Q9Y6Q5 intact:EBI-1776887 intact:EBI-752250|uniprotkb:Q9BSI8|uniprotkb:B2RDV5|ensembl:ENSP00000250244 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ap1m2_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-2 subunit(gene name synonym)|uniprotkb:Mu-adaptin 2(gene name synonym)|uniprotkb:AP-mu chain family member mu1B(gene name synonym)|uniprotkb:Mu1B-adaptin(gene name synonym)|uniprotkb:AP1M2(gene name)|psi-mi:AP1M2(display_short)|uniprotkb:Adaptor protein complex AP-1 subunit mu-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-2 medium chain 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507631|imex:IM-28562-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_005489.2|refseq:NP_001287816.1|ensembl:ENSG00000129354(gene)|ensembl:ENST00000250244(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722 - - - figure legend:ST2|comment:"Y2H screens hits: 11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:Zb94TVE2hogjzn1QKDV3vWRNsWo9606 rigid:u2ae3/xBQzUFBIfUzQjoG45QjYk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:O43909 intact:EBI-1776887 intact:EBI-1754679|uniprotkb:O00225|uniprotkb:Q53XT3|uniprotkb:D3DST8|ensembl:ENSP00000220562 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:extl3_human(display_long)|uniprotkb:EXTL3(gene name)|psi-mi:EXTL3(display_short)|uniprotkb:EXTL1L(gene name synonym)|uniprotkb:EXTR1(gene name synonym)|uniprotkb:KIAA0519(gene name synonym)|uniprotkb:Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase(gene name synonym)|uniprotkb:Putative tumor suppressor protein EXTL3(gene name synonym)|uniprotkb:Multiple exostosis-like protein 3(gene name synonym)|uniprotkb:Hereditary multiple exostoses gene isolog(gene name synonym)|uniprotkb:EXT-related protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507624|imex:IM-28562-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:XP_011542742.1|refseq:NP_001431.1|ensembl:ENSG00000012232(gene)|ensembl:ENST00000220562(transcript)|go:"GO:0001888"(glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0046872"(metal ion binding)|interpro:IPR004263(Exostosin-like)|interpro:IPR015338(EXTL2, alpha-1,4-N-acetylhexosaminyltransferase)|interpro:IPR029044|interpro:IPR040911|reactome:R-HSA-381038 - - - figure legend:ST2|comment:"Y2H screens hits: 14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:2G4jJX6fU7NM/2Q7itA3CTDW1gU9606 rigid:SUFWZmPP4h7pNFvF2rwu4quq/gA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:P68104 intact:EBI-1776887 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507617|imex:IM-28562-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST2|comment:"Y2H screens hits: 15"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:r3zzyo5YbgkZD4qrpqDHVP9YgYU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:P08571 intact:EBI-26506516 intact:EBI-3905196|uniprotkb:Q96L99|uniprotkb:Q53XT5|uniprotkb:Q9UNS3|uniprotkb:Q96FR6|ensembl:ENSP00000304236|ensembl:ENSP00000385519 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cd14_human(display_long)|uniprotkb:CD14(gene name)|psi-mi:CD14(display_short)|uniprotkb:Myeloid cell-specific leucine-rich glycoprotein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507610|imex:IM-28562-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000582.1|refseq:NP_001035110.1|refseq:NP_001167575.1|refseq:NP_001167576.1|dip:DIP-1030N|ensembl:ENSG00000170458(gene)|ensembl:ENST00000302014(transcript)|ensembl:ENST00000401743(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001847"(opsonin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016019"(peptidoglycan immune receptor activity)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR016337(Monocyte differentiation antigen CD14)|interpro:IPR032675|rcsb pdb:4GLP|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-975163|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling) - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:MpfQfOF+t0EMlzBio2kyYeJU3hE9606 rigid:B1CUOODPOhluGVzhi9lL7QcwhqE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:Q8IZC6 intact:EBI-26506516 intact:EBI-2529384|uniprotkb:Q66K43|uniprotkb:Q96JF7|ensembl:ENSP00000348385 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cora1_human(display_long)|uniprotkb:COL27A1(gene name)|psi-mi:COL27A1(display_short)|uniprotkb:KIAA1870(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507603|imex:IM-28562-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000196739(gene)|ensembl:ENST00000356083(transcript)|go:"GO:0003431"(growth plate cartilage chondrocyte development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005583"(fibrillar collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_116277.2 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:+Hwz0vac4YiN3eiJr0WxgHuQsiM9606 rigid:RUn79y7aW8kav8myaMNk/PKbpQg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:Q96EK4 intact:EBI-26506516 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507596|imex:IM-28562-1291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:OiIyWR8iz/KDry1rw9p5AXSFY8E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:P04733 intact:EBI-26506516 intact:EBI-10209483|uniprotkb:Q9UI97|ensembl:ENSP00000334872 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:mt1f_human(display_long)|uniprotkb:MT1F(gene name)|psi-mi:MT1F(display_short)|uniprotkb:Metallothionein-IF(gene name synonym)|uniprotkb:PRO0376(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507589|imex:IM-28562-1151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001288201.1|refseq:NP_005940.1|ensembl:ENSG00000198417(gene)|ensembl:ENST00000334350(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|reactome:R-HSA-5661231 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:gwJ22UrT1z8vNxqyRkEEzQ6Bhjg9606 rigid:JraQ4Qt7icBs5fN0jImtd5em2qU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:Q13572 intact:EBI-26506516 intact:EBI-751027|uniprotkb:Q9BTL6|uniprotkb:Q9H2E7|ensembl:ENSP00000267615|ensembl:ENSP00000451091|ensembl:ENSP00000483767|ensembl:ENSP00000486991 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itpk1_human(display_long)|uniprotkb:Inositol 1,3,4-trisphosphate 5/6-kinase(gene name synonym)|uniprotkb:ITPK1(gene name)|psi-mi:ITPK1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507582|imex:IM-28562-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001136065.1|refseq:NP_001136066.1|refseq:NP_055031.2|dip:DIP-60016N|go:"GO:0021915"(neural tube development)|go:"GO:0032957"(inositol trisphosphate metabolic process)|go:"GO:0047325"(inositol tetrakisphosphate 1-kinase activity)|go:"GO:0052725"(inositol-1,3,4-trisphosphate 6-kinase activity)|go:"GO:0052726"(inositol-1,3,4-trisphosphate 5-kinase activity)|go:"GO:0052746"(inositol phosphorylation)|go:"GO:0070266"(necroptotic process)|interpro:IPR008656(Inositol 1, 3, 4-trisphosphate 56-kinase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR040464|interpro:IPR041429|rcsb pdb:2ODT|rcsb pdb:2Q7D|rcsb pdb:2QB5|reactome:R-HSA-1855167|reactome:R-HSA-1855204|reactome:R-HSA-983231|ensembl:ENSG00000100605(gene)|ensembl:ENSG00000274958(gene)|ensembl:ENST00000267615(transcript)|ensembl:ENST00000556603(transcript)|ensembl:ENST00000614271(transcript)|ensembl:ENST00000626153(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000825"(inositol tetrakisphosphate 6-kinase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016853"(isomerase activity) - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:ctUD8uOEz+70jTAwW0e/bWp5OA49606 rigid:LnygmVkLaSnMggUC2vC2/J4WCZI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:P68104 intact:EBI-26506516 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507575|imex:IM-28562-795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:pXh0+l2szoh1VbpJ11A/yfeQpSc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:Q9Y3B6 intact:EBI-26506516 intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507568|imex:IM-28562-793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606 rigid:IZ3FK9/eZFuYa+C/oegiuysufsM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:O60814 intact:EBI-26506516 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507561|imex:IM-28562-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:ST2|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 rigid:r/z2Sd7UYC5AEjYLmvCXA7ZUKNI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:Q15038 intact:EBI-26506516 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507554|imex:IM-28562-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rigid:wW89QeL0qLQ+snzzGXpsBMKfXMU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24837 uniprotkb:P49755 intact:EBI-26506516 intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145 psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507547|imex:IM-28562-1149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3 - - - figure legend:ST2|comment:"Y2H screens hits: 11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606 rigid:OVJWd0jYeqkEYXQWz0Lxz6igiOc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02795 uniprotkb:P24837 intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185 intact:EBI-26506516 psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym) psi-mi:ve7_hpv39(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507540|imex:IM-28562-791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) - - - figure legend:ST2|comment:"Y2H screens hits: 29"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606 rogid:D+iX4f4v7gb73PAkSesp64mR9R010588 rigid:5kVoNrYVfJlDuEvT76yjB4N31vc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24835 uniprotkb:P07355 intact:EBI-11793707 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507533|imex:IM-28562-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:zRvPmsgpqsPZYKpDpYzzMNHCkmY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24835 uniprotkb:P04406 intact:EBI-11793707 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507526|imex:IM-28562-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rigid:VG9QzgxjqCKc4PCERy9OE6z8aZA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24835 uniprotkb:Q92530 intact:EBI-11793707 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507519|imex:IM-28562-789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 rigid:Ebr4y19vrwLNcazJDtuvqOD66F0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24835 uniprotkb:P06733 intact:EBI-11793707 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507512|imex:IM-28562-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:ST1|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:sP0RqMlRsEwP+tehpPZADbfrZ3g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24835 uniprotkb:P02792 intact:EBI-11793707 intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0 psi-mi:ve6_hpv39(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10588(Human papillomavirus type 39)|taxid:10588(Human papillomavirus type 39) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507505|imex:IM-28562-1147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575 refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N - - - figure legend:ST1|comment:"Y2H screens hits: 11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:xxm1vURtFYaxjP2q+OUUtEtvVfg10588 rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606 rigid:jA9degKWnm0Z9dr+Iw84Qrn5/AY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:Q9HCK8 intact:EBI-866453 intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENSP00000495240 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507848|imex:IM-28562-1299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENST00000430710|ensembl:ENSP00000406288|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENST00000645929|ensembl:ENSP00000494402|ensembl:ENSP00000495240|refseq:NP_001164100.1|refseq:NP_065971.2|go:"GO:0035064"(methylated histone binding)|go:"GO:0035176"(social behavior)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048565"(digestive tract development)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070615"|ensembl:ENSG00000100888(gene)|ensembl:ENST00000557364(transcript)|ensembl:ENST00000643469(transcript)|ensembl:ENST00000646647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|go:"GO:0071339"(MLL1 complex)|dip:DIP-38021N - - - figure legend:ST2|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:QwADLvHNwK00OAboBtAkqaICd489606 rigid:MuLB6r9h2JJsa6UfGrare98DoBs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P50479 intact:EBI-866453 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507841|imex:IM-28562-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:IU3tRR76ZaCG2gx1zzo0XBwPeOM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P68104 intact:EBI-866453 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507834|imex:IM-28562-997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST2|comment:"Y2H screens hits: 11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:8m0+U5NcM9ANm2XK7lDflFX0I8g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:Q15022 intact:EBI-866453 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507827|imex:IM-28562-1297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - - figure legend:ST2|comment:"Y2H screens hits: 18"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:ML42WFeJaTA1faFbg6omTrEwjko false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:O94885 intact:EBI-866453 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507820|imex:IM-28562-813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - - - figure legend:ST2|comment:"Y2H screens hits: 22"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:WiA+jQAUZuVtajq1zqjZL/dXzGs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P78330 intact:EBI-11737199 intact:EBI-1042956|uniprotkb:Q7Z3S5|uniprotkb:B2RCR5|ensembl:ENSP00000275605|ensembl:ENSP00000378854|ensembl:ENSP00000401639 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:serb_human(display_long)|uniprotkb:PSPH(gene name)|psi-mi:PSPH(display_short)|uniprotkb:O-phosphoserine phosphohydrolase(gene name synonym)|uniprotkb:L-3-phosphoserine phosphatase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507813|imex:IM-28562-1295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033574"(response to testosterone)|go:"GO:0036424"(L-phosphoserine phosphatase activity)|go:"GO:0036425"(obsolete D-phosphoserine phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|interpro:IPR004469(Phosphoserine phosphatase SerB)|interpro:IPR023214|interpro:IPR036412|rcsb pdb:1L8L|rcsb pdb:1L8O|rcsb pdb:1NNL|rcsb pdb:6HYJ|rcsb pdb:6HYY|rcsb pdb:6Q6J|reactome:R-HSA-977347|ensembl:ENSG00000146733(gene)|ensembl:ENST00000275605(transcript)|ensembl:ENST00000395471(transcript)|ensembl:ENST00000437355(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004647"|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|refseq:XP_006715823.1|refseq:NP_004568.2|refseq:XP_011513763.1|refseq:XP_005271830.1|refseq:XP_005271831.1|refseq:XP_005271832.1|refseq:XP_005271833.1|refseq:XP_016867955.1|refseq:XP_016867956.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:gmgkmgyMOyxcEWV7n4hjn1NYEyA9606 rigid:Ga+ctIKjxA0EGWxXCnE9s6FJ+Vk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P62851 intact:EBI-11737199 intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507806|imex:IM-28562-1293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606 rigid:poMCUQWdUtzOsvSMYXn/0tmHveY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:Q6ZN55 intact:EBI-11737199 intact:EBI-2818349|uniprotkb:Q6ZN10|uniprotkb:Q9H6N0|uniprotkb:Q8NCE3|uniprotkb:Q6IPE0|uniprotkb:Q7L5Z5|intact:EBI-28978517|ensembl:ENSP00000469029|ensembl:ENSP00000351939 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:zn574_human(display_long)|uniprotkb:ZNF574(gene name)|psi-mi:ZNF574(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507799|imex:IM-28562-811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:XP_011525530.1|refseq:XP_011525531.1|refseq:XP_011525532.1|refseq:NP_073589.4|ensembl:ENSP00000351939|ensembl:ENSP00000469029|refseq:XP_005259216.1|refseq:NP_001317448.1|ensembl:ENST00000359044(transcript)|ensembl:ENST00000600245(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000105732(gene) - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:Ntg8Cl91sPslQWwFJfCHYQ063IM9606 rigid:w9OUwr+rCnP8uC5zpb4MmApNroQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:Q14671 intact:EBI-11737199 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507792|imex:IM-28562-1157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:lusiDSmiG/pP4+IamAkSDePxVv0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:Q02878 intact:EBI-11737199 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507785|imex:IM-28562-995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:hcc+tG9fQGELxl831iptXsHLSuE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:Q15022 intact:EBI-11737199 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507778|imex:IM-28562-809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:Of7BYQ1H3PuCOEmuWYigptSlAKs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:Q9BUB7 intact:EBI-11737199 intact:EBI-726363|uniprotkb:Q9NWY5|uniprotkb:E9PDY9|ensembl:ENSP00000312599 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tmm70_human(display_long)|uniprotkb:TMEM70(gene name)|psi-mi:TMEM70(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507771|imex:IM-28562-993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001035703.1|refseq:NP_060336.3|ensembl:ENSG00000175606(gene)|ensembl:ENST00000312184(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR009724(Protein of unknown function DUF1301)|mint:Q9BUB7|go:"GO:0005743"(mitochondrial inner membrane) - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:6LHWSQP2W1CRBgylWi8Ncc3X/3E9606 rigid:Vou6EAOPH9GazqNapP866ncnO1w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P99999 intact:EBI-11737199 intact:EBI-446479|uniprotkb:A4D166|uniprotkb:P00001|uniprotkb:Q6NUR2|uniprotkb:Q6NX69|uniprotkb:Q96BV4|uniprotkb:B2R4I1|ensembl:ENSP00000307786|ensembl:ENSP00000386270|ensembl:ENSP00000387279 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cyc_human(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507764|imex:IM-28562-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_061820.1|dip:DIP-29683N|ensembl:ENSG00000172115(gene)|ensembl:ENST00000305786(transcript)|ensembl:ENST00000409409(transcript)|ensembl:ENST00000409764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045333"(cellular respiration)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|mint:P99999|rcsb pdb:1J3S|rcsb pdb:2N3Y|rcsb pdb:2N9I|rcsb pdb:2N9J|rcsb pdb:3NWV|rcsb pdb:3ZCF|rcsb pdb:3ZOO|rcsb pdb:5EXQ|rcsb pdb:5O10|rcsb pdb:5TY3|rcsb pdb:6DUJ|rcsb pdb:6ECJ|reactome:R-HSA-111457|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9627069|reactome:R-HSA-9707564 - - - figure legend:ST2|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:vSMR7doWXd3VBP8jmhl6cUjccdY9606 rigid:/j8DXRH5pTed4b/+DRUMKJFgseY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:O94885 intact:EBI-11737199 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507757|imex:IM-28562-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - - - figure legend:ST2|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:XrtN4li80dGiiYXliEt16AUF9jY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:O75376 intact:EBI-11737199 intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507750|imex:IM-28562-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1 - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606 rigid:YeZuZKdaFaRjQ34cC77O+4P4hZk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P01106 intact:EBI-11737199 intact:EBI-447544|intact:EBI-1058440|uniprotkb:P01107|uniprotkb:Q14026|uniprotkb:A8WFE7|ensembl:ENSP00000367207|ensembl:ENSP00000499105 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:myc_human(display_long)|uniprotkb:BHLHE39(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 39(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507743|imex:IM-28562-1155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_002458.2|dip:DIP-28143N|ensembl:ENSG00000136997(gene)|ensembl:ENST00000377970(transcript)|ensembl:ENST00000652288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035690"|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|mint:P01106|rcsb pdb:1A93|rcsb pdb:1EE4|rcsb pdb:1MV0|rcsb pdb:1NKP|rcsb pdb:2A93|rcsb pdb:2OR9|rcsb pdb:4Y7R|rcsb pdb:5I4Z|rcsb pdb:5I50|rcsb pdb:6C4U|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015671"(oxygen transport)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-4411364|reactome:R-HSA-5687128|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8866911|reactome:R-HSA-8951430|reactome:R-HSA-9018519|reactome:R-HSA-9616222 - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:CCk+p9FN7JV6cTmJDlin2hRp1tg9606 rigid:vn4P32kukElEhaXJM5QBAfmXMes false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P47869 intact:EBI-11737199 intact:EBI-2685723|uniprotkb:Q59G14|uniprotkb:A8K0U7|ensembl:ENSP00000348897|ensembl:ENSP00000371033|ensembl:ENSP00000421300|ensembl:ENSP00000421828|uniprotkb:B7Z1H8 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:gbra2_human(display_long)|uniprotkb:"GABA(A) receptor subunit alpha-2"(gene name synonym)|uniprotkb:GABRA2(gene name)|psi-mi:GABRA2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507736|imex:IM-28562-991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_000798.2|refseq:NP_001107647.1|refseq:NP_001273756.1|ensembl:ENSG00000151834(gene)|ensembl:ENST00000356504(transcript)|ensembl:ENST00000381620(transcript)|ensembl:ENST00000510861(transcript)|ensembl:ENST00000514090(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008503"(benzodiazepine receptor activity)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0098794"(postsynapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005432(Gamma-aminobutyric-acid A receptor, alpha 2 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-HSA-977443|refseq:NP_001317619.1|refseq:XP_016863471.1|refseq:XP_016863472.1 - - - figure legend:ST2|comment:"Y2H screens hits: 9"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:/vvJTpbWO9xWgB/pfSbRleFWVJ89606 rigid:ywdZWPNsiebDHXRjX99YtQ75sLA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:Q16836 intact:EBI-11737199 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507729|imex:IM-28562-1153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:ST2|comment:"Y2H screens hits: 9"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:QINiFLT888C91dt+kGC5SRDDhQQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P48047 intact:EBI-11737199 intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507722|imex:IM-28562-807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:ST2|comment:"Y2H screens hits: 10"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606 rigid:l+DIdqsOLTcKXovkqBpp8EuPX6g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P68104 intact:EBI-11737199 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507715|imex:IM-28562-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST2|comment:"Y2H screens hits: 10"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:tn9NE/lFYfd4s+SwrFCyQF78AOQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06429 uniprotkb:P17936 intact:EBI-11737199 intact:EBI-715709|uniprotkb:Q2V509|uniprotkb:Q6P1M6|uniprotkb:A4D2F5|uniprotkb:Q9UCL4|uniprotkb:D3DVM0|ensembl:ENSP00000477772 psi-mi:ve7_hpv33(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ibp3_human(display_long)|uniprotkb:IGFBP3(gene name)|psi-mi:IGFBP3(display_short)|uniprotkb:IBP3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10586(hpv33)|taxid:10586(Human papillomavirus type 33) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507708|imex:IM-28562-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000148(Papillomavirus E7 protein)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_000589.2|refseq:NP_001013416.1|ensembl:ENSG00000146674(gene)|ensembl:ENST00000613132(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012211(Insulin-like growth factor binding protein 3)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|mint:P17936|reactome:R-HSA-381426|reactome:R-HSA-6803211|reactome:R-HSA-8957275|refseq:XP_016867641.1|dip:DIP-40786N - - - figure legend:ST2|comment:"Y2H screens hits: 14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:0lYaOj5PkbJzA7xjb9VtCuGAyrE10586 rogid:zb2NzKqdY6oCXbF/DrT5etyMeEU9606 rigid:L8pQxNrmbMxjeBORF/0dx4rjS5M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:P08571 intact:EBI-1776887 intact:EBI-3905196|uniprotkb:Q96L99|uniprotkb:Q53XT5|uniprotkb:Q9UNS3|uniprotkb:Q96FR6|ensembl:ENSP00000304236|ensembl:ENSP00000385519 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cd14_human(display_long)|uniprotkb:CD14(gene name)|psi-mi:CD14(display_short)|uniprotkb:Myeloid cell-specific leucine-rich glycoprotein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507701|imex:IM-28562-799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_000582.1|refseq:NP_001035110.1|refseq:NP_001167575.1|refseq:NP_001167576.1|dip:DIP-1030N|ensembl:ENSG00000170458(gene)|ensembl:ENST00000302014(transcript)|ensembl:ENST00000401743(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001847"(opsonin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016019"(peptidoglycan immune receptor activity)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR016337(Monocyte differentiation antigen CD14)|interpro:IPR032675|rcsb pdb:4GLP|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-975163|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling) - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:MpfQfOF+t0EMlzBio2kyYeJU3hE9606 rigid:2qVcyW0WGAlae/pLyfE+Z3gLzk0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:P50479 intact:EBI-1776887 intact:EBI-372861|uniprotkb:Q96AT8|uniprotkb:Q9BTW8|uniprotkb:Q9Y292|uniprotkb:B2R8U1|uniprotkb:Q53Y39|ensembl:ENSP00000253754 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdli4_human(display_long)|uniprotkb:PDLIM4(gene name)|psi-mi:PDLIM4(display_short)|uniprotkb:RIL(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507694|imex:IM-28562-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD refseq:NP_001124499.1|refseq:NP_003678.2|ensembl:ENSG00000131435(gene)|ensembl:ENST00000253754(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|rcsb pdb:2EEG|rcsb pdb:2V1W|rcsb pdb:4Q2O - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:IZjRYe1ffifbziFhtrdU6zikQWA9606 rigid:pH/yyxJwfJMh6c7ByVrTbwfB0ng false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:Q16836 intact:EBI-1776887 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507687|imex:IM-28562-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:Z3PmfOC9xYOiPuJ9TwllBtrpHnM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02795 uniprotkb:P06788 intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185 intact:EBI-1776887 psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym) psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507680|imex:IM-28562-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rigid:807ZJ4DJi/UHsqGw1zwztCRbqrI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:Q9P225 intact:EBI-1776887 intact:EBI-2878049|uniprotkb:Q6ZR42|uniprotkb:B5MDX5|uniprotkb:A8K992|uniprotkb:Q6PIH3|uniprotkb:O15434|intact:EBI-28983125|ensembl:ENSP00000373825|ensembl:ENSP00000458355 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dyh2_human(display_long)|uniprotkb:DNAH2(gene name)|psi-mi:DNAH2(display_short)|uniprotkb:DNAHC2(gene name synonym)|uniprotkb:DNHD3(gene name synonym)|uniprotkb:KIAA1503(gene name synonym)|uniprotkb:Axonemal beta dynein heavy chain 2(gene name synonym)|uniprotkb:Ciliary dynein heavy chain 2(gene name synonym)|uniprotkb:Dynein heavy chain domain-containing protein 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507673|imex:IM-28562-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041589|interpro:IPR041658|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030286"(dynein complex)|go:"GO:0031514"(motile cilium)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045505"(dynein intermediate chain binding)|interpro:IPR042219|go:"GO:0051959"(dynein light intermediate chain binding)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|go:"GO:0060285"(cilium-dependent cell motility)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|ensembl:ENSG00000183914(gene)|ensembl:ENST00000389173(transcript)|ensembl:ENST00000572933(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005858"(axonemal dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|refseq:XP_011521969.1|refseq:NP_065928.2|ensembl:ENSP00000373825|ensembl:ENST00000570791|ensembl:ENSP00000460245|ensembl:ENSP00000458355|refseq:NP_001290199.1 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:u9WUoT4L2d5c6Ha0L+A3XsEqKC09606 rigid:jXa4T3uZYdeRAflsFxjEjnZi7uA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:Q9UBS4 intact:EBI-1776887 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507666|imex:IM-28562-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:8ABDOCtBLppquFoeb22HZ+2qTzU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06788 uniprotkb:Q8WWH5 intact:EBI-1776887 intact:EBI-6658513|ensembl:ENSP00000298746|uniprotkb:Q53ES2|uniprotkb:B2R716 psi-mi:ve7_hpv18(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:trub1_human(display_long)|uniprotkb:TRUB1(gene name)|psi-mi:TRUB1(display_short)|uniprotkb:PUS4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507659|imex:IM-28562-989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-45143N|mint:P06788|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:6IWD ensembl:ENSG00000165832(gene)|ensembl:ENST00000298746(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR014780(tRNA pseudouridine synthase B, N-terminal, bacterial-type)|interpro:IPR020103|refseq:NP_631908.1 - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/14 rogid:CtViGx9Y6K96UpWVBR1904DpdpA333761 rogid:gjrCu9R/KVmdnMW7pbffs6CISwI9606 rigid:aFCddDNs+jXobVGf1YU/r54Ubfg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:Q15038 intact:EBI-26506039 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507968|imex:IM-28562-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rigid:vA66F/RVtrPjRH5yVlkUsgP6jHs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:O94885 intact:EBI-26506039 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507961|imex:IM-28562-757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - - - figure legend:ST2|comment:"Y2H screens hits: 16"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:uL5dX3qPyb/0eniIL7qeOO3JNl4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:P68104 intact:EBI-26506039 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507954|imex:IM-28562-1303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST2|comment:"Y2H screens hits: 19"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:1LKCAaDR5ClkDCLN0W2UP8ujFGY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:O94842 intact:EBI-866453 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507947|imex:IM-28562-1301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:wtw9ZLC0YwKeLcWiga1d3XgUnLU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P62854 intact:EBI-866453 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507940|imex:IM-28562-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 rigid:0mWr/s3qBpcUhrHNznE25xMICo8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P00395 intact:EBI-866453 intact:EBI-2117234|uniprotkb:Q34770|ensembl:ENSP00000354499 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cox1_human(display_long)|uniprotkb:MT-CO1(gene name)|psi-mi:MT-CO1(display_short)|uniprotkb:COI(gene name synonym)|uniprotkb:COXI(gene name synonym)|uniprotkb:MTCO1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide I(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507933|imex:IM-28562-819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:YP_003024028.1|ensembl:ENSG00000198804(gene)|ensembl:ENST00000361624(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0020037"(heme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|interpro:IPR000883(Cytochrome c oxidase, subunit I)|interpro:IPR023615|interpro:IPR023616|interpro:IPR033944|interpro:IPR036927|mint:P00395|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:hPHsY8UxxIWcLFkR9oIoZH5vtls9606 rigid:pY1aBR4X3VY3ySKL3Xo4gHBPrQA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P17936 intact:EBI-866453 intact:EBI-715709|uniprotkb:Q2V509|uniprotkb:Q6P1M6|uniprotkb:A4D2F5|uniprotkb:Q9UCL4|uniprotkb:D3DVM0|ensembl:ENSP00000477772 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ibp3_human(display_long)|uniprotkb:IGFBP3(gene name)|psi-mi:IGFBP3(display_short)|uniprotkb:IBP3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507926|imex:IM-28562-999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_000589.2|refseq:NP_001013416.1|ensembl:ENSG00000146674(gene)|ensembl:ENST00000613132(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012211(Insulin-like growth factor binding protein 3)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|mint:P17936|reactome:R-HSA-381426|reactome:R-HSA-6803211|reactome:R-HSA-8957275|refseq:XP_016867641.1|dip:DIP-40786N - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:zb2NzKqdY6oCXbF/DrT5etyMeEU9606 rigid:WlowHDNu9bOx3WbbM18JA/fS+Ls false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:O60814 intact:EBI-866453 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507919|imex:IM-28562-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 rigid:/ZzBNuR0kVlsmgMtwk9dfYCA/Os false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P03905 intact:EBI-866453 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507912|imex:IM-28562-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:G+50Aou88aNLFCiN6pe0LIhQYUE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:Q16836 intact:EBI-866453 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507905|imex:IM-28562-817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:F0WOBFpCxK5WvBF798VDvbzxVPw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P13667 intact:EBI-866453 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507898|imex:IM-28562-1179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:l+E/bCoO6o/AAYZ8aeXEKE617wg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:Q02878 intact:EBI-866453 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507891|imex:IM-28562-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:wnIIUSeKXHXEouZW3JenzPH6FNU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:P62081 intact:EBI-866453 intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507884|imex:IM-28562-1159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606 rigid:mMkOvi77Mj018vtwP6AWMXP5s+Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03129 uniprotkb:Q66K74 intact:EBI-866453 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve7_hpv16(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507877|imex:IM-28562-815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041326.1|dip:DIP-1090N|mint:P03129|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|interpro:IPR000148(Papillomavirus E7 protein)|rcsb pdb:4YOZ|rcsb pdb:6APN ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:O1EL1sc/Ks4kPu1hY4hB3gQ26MM333760 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:/NjzqIl6KBW9taeBmrky72/92k8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q8IWX8 intact:EBI-26505276 intact:EBI-2555370|uniprotkb:O00302|uniprotkb:Q99492|uniprotkb:Q4G0Y5|uniprotkb:Q8WU30|ensembl:ENSP00000439856 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cherp_human(display_long)|uniprotkb:DAN26(gene name synonym)|uniprotkb:SCAF6(gene name synonym)|uniprotkb:SR-related CTD-associated factor 6(gene name synonym)|uniprotkb:ERPROT 213-21(gene name synonym)|uniprotkb:CHERP(gene name)|psi-mi:CHERP(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508164|imex:IM-28562-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_006378.3|ensembl:ENSG00000085872(gene)|ensembl:ENST00000546361(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007399"(nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035967|interpro:IPR039037|reactome:R-HSA-72163 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:Snifq3RgcsxZ8r9MCExHeb242Ss9606 rigid:XUcU646qiGdwjnShrNztHBkVBF0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:Q02878 intact:EBI-26506039 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507982|imex:IM-28562-1255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:RvAr4rZ2/4S1ZHPzriIOf8AyxuE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:P62906 intact:EBI-26505276 intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508150|imex:IM-28562-1275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606 rigid:Q+SdzkNaFF/cOnx2Xx7ZWPoRjJI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q8WWH5 intact:EBI-26505276 intact:EBI-6658513|ensembl:ENSP00000298746|uniprotkb:Q53ES2|uniprotkb:B2R716 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:trub1_human(display_long)|uniprotkb:TRUB1(gene name)|psi-mi:TRUB1(display_short)|uniprotkb:PUS4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508143|imex:IM-28562-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000165832(gene)|ensembl:ENST00000298746(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR014780(tRNA pseudouridine synthase B, N-terminal, bacterial-type)|interpro:IPR020103|refseq:NP_631908.1 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:gjrCu9R/KVmdnMW7pbffs6CISwI9606 rigid:EXV7qHzmpucjte1BgJh91/MdFac false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q96EK4 intact:EBI-26505276 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508136|imex:IM-28562-1273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS - - crc64:25235D20CB54D8C2 figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:fSPq9QTa3UKD7jj//nIXm51Enrc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q9P0J6 intact:EBI-26505276 intact:EBI-2115401|uniprotkb:Q3SWV6|uniprotkb:Q9UKL7|uniprotkb:A4UCS0|uniprotkb:B2R4Z2|ensembl:ENSP00000372093|ensembl:ENSP00000423152|ensembl:ENSP00000423399|ensembl:ENSP00000427152 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:rm36_human(display_long)|uniprotkb:MRPL36(gene name)|psi-mi:MRPL36(display_short)|uniprotkb:BRIP1(gene name synonym)|uniprotkb:BRCA1-interacting protein 1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL36m(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508129|imex:IM-28562-1271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_115868.1|refseq:XP_016865239.1|refseq:XP_016865240.1|refseq:XP_016865241.1|ensembl:ENSG00000171421(gene)|ensembl:ENST00000382647(transcript)|ensembl:ENST00000505059(transcript)|ensembl:ENST00000505818(transcript)|ensembl:ENST00000508987(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0016604"(nuclear body)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR000473(Ribosomal protein L36)|interpro:IPR035977|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:ST2|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:R7keFxdS+POZzXaUtEE09rN6HqA9606 rigid:xoUC4KD92nKdRH13nAcg6gNBKrQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q16836 intact:EBI-26505276 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508122|imex:IM-28562-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:ST2|comment:"Y2H screens hits: 6"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:6GN5sTxGuaVf+MQ3ODm4bJlcZp0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02795 uniprotkb:P36817 intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185 intact:EBI-26505276 psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym) psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508115|imex:IM-28562-1269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rigid:25cn66PVRm03IjL9UxuLQzQamQY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:O60814 intact:EBI-26505276 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508108|imex:IM-28562-1117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:ST2|comment:"Y2H screens hits: 11"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 rigid:reDd3mgU0zTlSPPYgfdsg/adouU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:P00395 intact:EBI-26505276 intact:EBI-2117234|uniprotkb:Q34770|ensembl:ENSP00000354499 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cox1_human(display_long)|uniprotkb:MT-CO1(gene name)|psi-mi:MT-CO1(display_short)|uniprotkb:COI(gene name synonym)|uniprotkb:COXI(gene name synonym)|uniprotkb:MTCO1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide I(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508101|imex:IM-28562-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:YP_003024028.1|ensembl:ENSG00000198804(gene)|ensembl:ENST00000361624(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0020037"(heme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|interpro:IPR000883(Cytochrome c oxidase, subunit I)|interpro:IPR023615|interpro:IPR023616|interpro:IPR033944|interpro:IPR036927|mint:P00395|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:ST2|comment:"Y2H screens hits: 14"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:hPHsY8UxxIWcLFkR9oIoZH5vtls9606 rigid:72Lx6wc9YtP4sDP1sZlTZCeWZOg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:P16144 intact:EBI-26504932 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508094|imex:IM-28562-1115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rigid:GGCM5F6R4d5z99IcfPqEFPEij+0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:Q6P0N0 intact:EBI-26504932 intact:EBI-9870821|uniprotkb:D3DSA7|uniprotkb:Q86V14|uniprotkb:Q96PY4|uniprotkb:Q9NUR5|uniprotkb:Q9Y4X9|ensembl:ENSP00000309790 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:m18bp_human(display_long)|uniprotkb:MIS18BP1(gene name)|psi-mi:MIS18BP1(display_short)|uniprotkb:C14orf106(gene name synonym)|uniprotkb:KIAA1903(gene name synonym)|uniprotkb:KNL2(gene name synonym)|uniprotkb:M18BP1(gene name synonym)|uniprotkb:Kinetochore-associated protein KNL-2 homolog(gene name synonym)|uniprotkb:P243(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508087|imex:IM-28562-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_060823.3|refseq:XP_005267890.1|refseq:XP_016876914.1|ensembl:ENSG00000129534(gene)|ensembl:ENST00000310806(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015216(SANT associated)|interpro:IPR017884|interpro:IPR017930|interpro:IPR039110|rcsb pdb:1WGX|reactome:R-HSA-606279 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:/2olIhyXaHJDtS5Yrj3zI8I/d+09606 rigid:7tt12Lsfb/oDWGJAoHqThcSm0Hk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:Q8WWH5 intact:EBI-26504932 intact:EBI-6658513|ensembl:ENSP00000298746|uniprotkb:Q53ES2|uniprotkb:B2R716 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:trub1_human(display_long)|uniprotkb:TRUB1(gene name)|psi-mi:TRUB1(display_short)|uniprotkb:PUS4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508080|imex:IM-28562-1267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000165832(gene)|ensembl:ENST00000298746(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR014780(tRNA pseudouridine synthase B, N-terminal, bacterial-type)|interpro:IPR020103|refseq:NP_631908.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:gjrCu9R/KVmdnMW7pbffs6CISwI9606 rigid:VswaVvuYsCqjuwhG57nNgHOM+e0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:Q9BUB7 intact:EBI-26504932 intact:EBI-726363|uniprotkb:Q9NWY5|uniprotkb:E9PDY9|ensembl:ENSP00000312599 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:tmm70_human(display_long)|uniprotkb:TMEM70(gene name)|psi-mi:TMEM70(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508073|imex:IM-28562-779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001035703.1|refseq:NP_060336.3|ensembl:ENSG00000175606(gene)|ensembl:ENST00000312184(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR009724(Protein of unknown function DUF1301)|mint:Q9BUB7|go:"GO:0005743"(mitochondrial inner membrane) - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:6LHWSQP2W1CRBgylWi8Ncc3X/3E9606 rigid:NhVgW38yW843+h+bLUn0XozQEJs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:P68104 intact:EBI-26504932 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508066|imex:IM-28562-1113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:/lUSS141gokaqSXxh90IW23ENWc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:Q66K74 intact:EBI-26504932 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508059|imex:IM-28562-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:Rq2ETQ6gPWd/WLOA5MqH+L0wezo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:Q9HCK8 intact:EBI-26506039 intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENSP00000495240 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507975|imex:IM-28562-1253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENST00000430710|ensembl:ENSP00000406288|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENST00000645929|ensembl:ENSP00000494402|ensembl:ENSP00000495240|refseq:NP_001164100.1|refseq:NP_065971.2|go:"GO:0035064"(methylated histone binding)|go:"GO:0035176"(social behavior)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048565"(digestive tract development)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070615"|ensembl:ENSG00000100888(gene)|ensembl:ENST00000557364(transcript)|ensembl:ENST00000643469(transcript)|ensembl:ENST00000646647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|go:"GO:0071339"(MLL1 complex)|dip:DIP-38021N - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:QwADLvHNwK00OAboBtAkqaICd489606 rigid:zYpyD6RTQ+jabAIiunlAK9/3dnQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:O94885 intact:EBI-26505276 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508157|imex:IM-28562-1277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:HVSg//nLjYwQsaIBGOj93Uv9KrQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:Q16836 intact:EBI-26506039 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507989|imex:IM-28562-1257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:VylOjlhA0LHmsqv7mQBLragC8tM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06465 uniprotkb:Q16836 intact:EBI-963841 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508244|imex:IM-28562-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:ST2|comment:"Y2H screens hits: 8"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:jQ/Isf3Geerqtwi4RqhV9ctFjvc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:P14550 intact:EBI-26505276 intact:EBI-372388|uniprotkb:A8KAL8|uniprotkb:Q6IAZ4|ensembl:ENSP00000312606|ensembl:ENSP00000361140|ensembl:ENSP00000480713|uniprotkb:D3DQ04 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:ak1a1_human(display_long)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:AKR1A1(gene name)|psi-mi:AKR1A1(display_short)|uniprotkb:ALDR1(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:"Alcohol dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:Glucuronate reductase(gene name synonym)|uniprotkb:Glucuronolactone reductase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508237|imex:IM-28562-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001189342.1|refseq:NP_001189343.1|refseq:NP_006057.1|refseq:NP_697021.1|ensembl:ENSG00000117448(gene)|ensembl:ENST00000351829(transcript)|ensembl:ENST00000372070(transcript)|ensembl:ENST00000621846(transcript)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019640"(glucuronate catabolic process to xylulose 5-phosphate)|go:"GO:0019853"(L-ascorbic acid biosynthetic process)|go:"GO:0042840"(D-glucuronate catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0046185"(aldehyde catabolic process)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047939"(L-glucuronate reductase activity)|go:"GO:0047941"(glucuronolactone reductase activity)|go:"GO:0047956"(glycerol dehydrogenase [NADP+] activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1990002"("methylglyoxal reductase (NADPH-dependent, acetol producing)")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044481|rcsb pdb:2ALR|reactome:R-HSA-156590|reactome:R-HSA-5661270 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:MWIly3lvCgExPs2LWAgQCeYe3aw9606 rigid:MNfl7Be2mdu6FH0H3bQrcngxPAk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:O95425 intact:EBI-26505276 intact:EBI-487145|uniprotkb:O60611|uniprotkb:O60612|uniprotkb:Q5VZK5|uniprotkb:Q5VZK6|uniprotkb:Q9H1R7|uniprotkb:D3DRW9|ensembl:ENSP00000348128|uniprotkb:M1J557 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:svil_human(display_long)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508230|imex:IM-28562-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) go:"GO:0007519"(skeletal muscle tissue development)|refseq:NP_003165.2|refseq:NP_068506.2|ensembl:ENSG00000197321(gene)|ensembl:ENST00000355867(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|interpro:IPR007123(Gelsolin region)|interpro:IPR015628(Supervillin)|interpro:IPR029006|interpro:IPR036886|mint:O95425|rcsb pdb:2K6M|rcsb pdb:2K6N|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0043034"(costamere)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin) - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:5FaBAFdOX+nPJzTwEdBt8e5Keng9606 rigid:WSyXaNuIrG44kfrfJLVV6qWabvc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:P60709 intact:EBI-26505276 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508223|imex:IM-28562-1139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rigid:ptE6l6T0n4NehFGh/ronFhtq4ww false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:P08571 intact:EBI-26505276 intact:EBI-3905196|uniprotkb:Q96L99|uniprotkb:Q53XT5|uniprotkb:Q9UNS3|uniprotkb:Q96FR6|ensembl:ENSP00000304236|ensembl:ENSP00000385519 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cd14_human(display_long)|uniprotkb:CD14(gene name)|psi-mi:CD14(display_short)|uniprotkb:Myeloid cell-specific leucine-rich glycoprotein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508216|imex:IM-28562-1119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_000582.1|refseq:NP_001035110.1|refseq:NP_001167575.1|refseq:NP_001167576.1|dip:DIP-1030N|ensembl:ENSG00000170458(gene)|ensembl:ENST00000302014(transcript)|ensembl:ENST00000401743(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001847"(opsonin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016019"(peptidoglycan immune receptor activity)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR016337(Monocyte differentiation antigen CD14)|interpro:IPR032675|rcsb pdb:4GLP|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-975163|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling) - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:MpfQfOF+t0EMlzBio2kyYeJU3hE9606 rigid:G7PdzpJ2vGy+BF4CHuxGNa5o0cs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q14671 intact:EBI-26505276 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508209|imex:IM-28562-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:KcFF7FQWdwzQEf12mIPGoHexVCc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:P63302 intact:EBI-26505276 intact:EBI-26508171|ensembl:ENSP00000470941|ensembl:ENSP00000471149|ensembl:ENSP00000473185|uniprotkb:A8MRR7|uniprotkb:O15532|uniprotkb:O19096|uniprotkb:Q86TI9|uniprotkb:Q96KM5 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:selw_human(display_long)|uniprotkb:SELENOW(gene name)|psi-mi:SELENOW(display_short)|uniprotkb:SELW(gene name synonym)|uniprotkb:SEPW1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508195|imex:IM-28562-979 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000178980(gene)|ensembl:ENST00000593892(transcript)|ensembl:ENST00000595615(transcript)|ensembl:ENST00000601048(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010269"(response to selenium ion)|go:"GO:0016209"(antioxidant activity)|interpro:IPR011893(SelT/selW/selH selenoprotein)|interpro:IPR036249|refseq:NP_003000.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:pqQ7h+0WVj4YveTA3w6HjWVAtCA9606 rigid:sg9AmYywbUbRaWORgjFqrTs8ZVY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36817 uniprotkb:Q6P0N0 intact:EBI-26505276 intact:EBI-9870821|uniprotkb:D3DSA7|uniprotkb:Q86V14|uniprotkb:Q96PY4|uniprotkb:Q9NUR5|uniprotkb:Q9Y4X9|ensembl:ENSP00000309790 psi-mi:ve7_hpv09(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:m18bp_human(display_long)|uniprotkb:MIS18BP1(gene name)|psi-mi:MIS18BP1(display_short)|uniprotkb:C14orf106(gene name synonym)|uniprotkb:KIAA1903(gene name synonym)|uniprotkb:KNL2(gene name synonym)|uniprotkb:M18BP1(gene name synonym)|uniprotkb:Kinetochore-associated protein KNL-2 homolog(gene name synonym)|uniprotkb:P243(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10621(Human papillomavirus type 9)|taxid:10621(Human papillomavirus type 9) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508202|imex:IM-28562-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041862.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_060823.3|refseq:XP_005267890.1|refseq:XP_016876914.1|ensembl:ENSG00000129534(gene)|ensembl:ENST00000310806(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015216(SANT associated)|interpro:IPR017884|interpro:IPR017930|interpro:IPR039110|rcsb pdb:1WGX|reactome:R-HSA-606279 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:j6hKnz3KPR+MaG6i7PMddbuKl2A10621 rogid:/2olIhyXaHJDtS5Yrj3zI8I/d+09606 rigid:xbECkjCEDuMnaZxyTz/rZ1fS7h4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02795 uniprotkb:Q84292 intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185 intact:EBI-26504932 psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym) psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508052|imex:IM-28562-1111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) - - - figure legend:ST2|comment:"Y2H screens hits: 5"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rigid:mSphthFmkqpAp7EJmlBw70aYlds false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:Q9UHR5 intact:EBI-26504932 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508045|imex:IM-28562-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 - - - figure legend:ST2|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rigid:7sAbBc/aX0lXF5MSnHeS7sylihM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:P03905 intact:EBI-26504932 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508038|imex:IM-28562-759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:ST2|comment:"Y2H screens hits: 7"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:qq7G6n2OcPdhPLHJuD6cOD7zdbM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q84292 uniprotkb:O94885 intact:EBI-26504932 intact:EBI-1761310|uniprotkb:Q8TAI0|uniprotkb:Q9H7R7|uniprotkb:Q5TGN5|intact:EBI-28974451|ensembl:ENSP00000356437 psi-mi:ve7_hpv6a(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:sash1_human(display_long)|uniprotkb:SASH1(gene name)|psi-mi:SASH1(display_short)|uniprotkb:KIAA0790(gene name synonym)|uniprotkb:PEPE1(gene name synonym)|uniprotkb:Proline-glutamate repeat-containing protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:37122(hpv6a)|taxid:37122(Human papillomavirus type 6a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508031|imex:IM-28562-1109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSP00000356437|refseq:NP_056093.3|ensembl:ENSG00000111961(gene)|ensembl:ENST00000367467(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1900044"(regulation of protein K63-linked ubiquitination)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902498"(regulation of protein autoubiquitination)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021090|interpro:IPR035720|interpro:IPR036028|interpro:IPR037627|interpro:IPR037630|mint:O94885|rcsb pdb:2DL0|rcsb pdb:2EBP - - - figure legend:ST2|comment:"Y2H screens hits: 12"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:1/BhAO73Dr+OmGm+uYWCv5/sT7s37122 rogid:fPsGpumoRog+/jCRGb7qpcVABno9606 rigid:9dHraaVu+fBntN2VqH2zCLYEbTg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:P00414 intact:EBI-26506039 intact:EBI-3932264|uniprotkb:Q14Y83|ensembl:ENSP00000354982 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:cox3_human(display_long)|uniprotkb:MT-CO3(gene name)|psi-mi:MT-CO3(display_short)|uniprotkb:COIII(gene name synonym)|uniprotkb:COXIII(gene name synonym)|uniprotkb:MTCO3(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide III(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508024|imex:IM-28562-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000198938(gene)|ensembl:ENST00000362079(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015453"(oxidoreduction-driven active transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045277"(respiratory chain complex IV)|interpro:IPR000298(Cytochrome c oxidase, subunit III)|interpro:IPR013833(Cytochrome c oxidase, subunit III, 4-helical bundle)|interpro:IPR024791|interpro:IPR033945|interpro:IPR035973|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:YP_003024032.1 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:ZsGHu+XXEfFZZecGf4EIhwQejAA9606 rigid:+shAf4VQR5M3eG/tTSWaGE1fVGw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:P06733 intact:EBI-26506039 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508017|imex:IM-28562-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:b95i70prkLOsBMkHov/3Q+kZx9I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:Q86SG4 intact:EBI-26506039 intact:EBI-2871339|uniprotkb:Q495B5|uniprotkb:Q86SH8|uniprotkb:Q8N8I5|intact:EBI-28986208 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:dpca2_human(display_long)|uniprotkb:HMGN2P46(gene name)|psi-mi:HMGN2P46(display_short)|uniprotkb:C15orf21(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2 pseudogene 46(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508010|imex:IM-28562-977 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization) - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:RoQQmY6JRWcuf5NQFhTo8aVuKa89606 rigid:WVLZ3Qy8Q006DCO15xu9tVrshK8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:P03905 intact:EBI-26506039 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508003|imex:IM-28562-1259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:uOX3n81z2U1CIroV/7/xnhufmjw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36827 uniprotkb:Q66K74 intact:EBI-26506039 intact:EBI-2133734|uniprotkb:Q8N3W5|uniprotkb:Q8NI88|uniprotkb:Q8N3L8|uniprotkb:Q27QB1|uniprotkb:Q96H94|uniprotkb:Q96IT4|uniprotkb:Q96SP8|uniprotkb:Q9BRC6|uniprotkb:Q9H928|uniprotkb:Q9NVK7|uniprotkb:Q6NXF1|ensembl:ENSP00000325313|intact:EBI-2556419|intact:EBI-10978604|uniprotkb:B4DH53|intact:EBI-28978421 psi-mi:ve7_hpv32(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:map1s_human(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym)|uniprotkb:BPY2-interacting protein 1(gene name synonym)|uniprotkb:Microtubule-associated protein 8(gene name synonym)|uniprotkb:Variable charge Y chromosome 2-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:333763(hpv32)|taxid:333763(Human papillomavirus type 32) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26507996|imex:IM-28562-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_041802.1|interpro:IPR000148(Papillomavirus E7 protein) ensembl:ENSG00000130479(gene)|ensembl:ENST00000324096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|refseq:NP_001295292.1|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010848"(regulation of chromatin disassembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|interpro:IPR026074|ensembl:ENSP00000325313|ensembl:ENST00000544059|ensembl:ENSP00000439243|refseq:NP_060644.4|interpro:IPR027322|mint:Q66K74 - - - figure legend:ST2|comment:"Y2H screens hits: 4"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:V8oH7w5DZcKfs8jFrWr08P8GpGw333763 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:5wOFXezVvFKDyA5ZsqL1T0YPyXQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00403 uniprotkb:P06465 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-963841 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508291|imex:IM-28562-1279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rigid:zSoM0cQx44fPtYMzrv4KtTKHRJc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06465 uniprotkb:Q99729 intact:EBI-963841 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ve7_hpv1(display_long)|uniprotkb:E7(gene name)|psi-mi:E7(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Neveu et al. (2012) pubmed:22898364|doi:10.1016/j.ymeth.2012.07.029|imex:IM-28562 taxid:10583(hpv1a)|taxid:10583(Human papillomavirus type 1a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26508298|imex:IM-28562-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR000148(Papillomavirus E7 protein)|refseq:NP_040307.1|rcsb pdb:2B9D refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:ST2|comment:"Y2H screens hits: 3"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/09 2020/12/11 rogid:Z+FmWl83xT2netHWYN38xAA4QoU10583 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:FRXWNvi6eGIrDtt+5KzKxtPxSNo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)