#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O88895 uniprotkb:P25799-1 intact:EBI-302263|uniprotkb:O88896 intact:EBI-643974|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:p25799-1(display_long)|uniprotkb:p105(isoform synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yan et al. (2012) pubmed:22891325|doi:10.1073/pnas.1119842109|imex:IM-20703 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16006940|imex:IM-20703-1|dip:DIP-190349E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 intact:EBI-643958(nfkb1_mouse)|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:hwBGAG63exwK1hmAMTrEiyZ5wpA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60974 uniprotkb:O88895 intact:EBI-349004|uniprotkb:Q60812 intact:EBI-302263|uniprotkb:O88896 psi-mi:ncor1_mouse(display_long)|uniprotkb:Ncor1(gene name)|psi-mi:Ncor1(display_short)|uniprotkb:Rxrip13(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 13(gene name synonym) psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yan et al. (2012) pubmed:22891325|doi:10.1073/pnas.1119842109|imex:IM-20703 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16006957|imex:IM-20703-2|dip:DIP-190350E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0002361"(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051225"(spindle assembly)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|go:"GO:0046965"(retinoid X receptor binding)|reactome:R-MMU-383280|reactome:R-MMU-9029569|reactome:R-MMU-9623433|reactome:R-MMU-9707564|reactome:R-MMU-400206|mint:Q60974|dip:DIP-32548N go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:5IfmxD5K9s0dYCZ6AOMwaBDElFs10090 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 rigid:9yI2bu3Zu67UOem3Ka4C61rTo1w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60974 uniprotkb:P25799-1 intact:EBI-349004|uniprotkb:Q60812 intact:EBI-643974|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:ncor1_mouse(display_long)|uniprotkb:Ncor1(gene name)|psi-mi:Ncor1(display_short)|uniprotkb:Rxrip13(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 13(gene name synonym) psi-mi:p25799-1(display_long)|uniprotkb:p105(isoform synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yan et al. (2012) pubmed:22891325|doi:10.1073/pnas.1119842109|imex:IM-20703 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16006957|imex:IM-20703-2|dip:DIP-190350E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0002361"(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051225"(spindle assembly)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|go:"GO:0046965"(retinoid X receptor binding)|reactome:R-MMU-383280|reactome:R-MMU-9029569|reactome:R-MMU-9623433|reactome:R-MMU-9707564|reactome:R-MMU-400206|mint:Q60974|dip:DIP-32548N intact:EBI-643958(nfkb1_mouse)|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:5IfmxD5K9s0dYCZ6AOMwaBDElFs10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:9yI2bu3Zu67UOem3Ka4C61rTo1w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)