#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P60514 uniprotkb:Q1XA76 intact:EBI-16002043 intact:EBI-15659618|ensembl:ENSGALP00000057289 psi-mi:txp1_psaca(display_long)|uniprotkb:Pi-theraphotoxin-Pc1a(gene name synonym)|uniprotkb:PcTx1(gene name synonym) psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Baconguis et al. (2012) pubmed:22842900|doi:10.1038/nature11375|imex:IM-18071 taxid:179874(psaca)|taxid:179874(Psalmopoeus cambridgei) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16002056|imex:IM-18071-1|dip:DIP-189736E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1LMM|rcsb pdb:2KNI|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|dip:DIP-59909N ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:fqK7Ho3YLD1EBy+ZqWKFkvKNDU8179874 rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031 rigid:8tKHw/doiq++3IYoRQktZMZPdo8 false - sufficient binding region:14-463 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q1XA76 uniprotkb:Q1XA76 intact:EBI-15659618|ensembl:ENSGALP00000057289 intact:EBI-15659618|ensembl:ENSGALP00000057289 psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym) psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Baconguis et al. (2012) pubmed:22842900|doi:10.1038/nature11375|imex:IM-18071 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16002075|imex:IM-18071-2|dip:DIP-187489E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/07 2017/08/10 rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031 rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031 rigid:EfvUqVuFP+M1HaBwoRP7WURMwwI false sufficient binding region:14-463 sufficient binding region:14-463 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60514 uniprotkb:Q1XA76 intact:EBI-16002043 intact:EBI-15659618|ensembl:ENSGALP00000057289 psi-mi:txp1_psaca(display_long)|uniprotkb:Pi-theraphotoxin-Pc1a(gene name synonym)|uniprotkb:PcTx1(gene name synonym) psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Baconguis et al. (2012) pubmed:22842900|doi:10.1038/nature11375|imex:IM-18071 taxid:179874(psaca)|taxid:179874(Psalmopoeus cambridgei) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16002094|imex:IM-18071-3|dip:DIP-189736E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1LMM|rcsb pdb:2KNI|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|dip:DIP-59909N ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:fqK7Ho3YLD1EBy+ZqWKFkvKNDU8179874 rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031 rigid:8tKHw/doiq++3IYoRQktZMZPdo8 false - sufficient binding region:14-463 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q1XA76 uniprotkb:Q1XA76 intact:EBI-15659618|ensembl:ENSGALP00000057289 intact:EBI-15659618|ensembl:ENSGALP00000057289 psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym) psi-mi:asic1_chick(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Baconguis et al. (2012) pubmed:22842900|doi:10.1038/nature11375|imex:IM-18071 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16002113|imex:IM-18071-4|dip:DIP-187489E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N ensembl:ENSGALG00000034025(gene)|ensembl:ENSGALT00000055224(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:2QTS|rcsb pdb:3IJ4|rcsb pdb:3S3W|rcsb pdb:3S3X|rcsb pdb:4FZ0|rcsb pdb:4FZ1|rcsb pdb:4NTW|rcsb pdb:4NTX|rcsb pdb:4NTY|rcsb pdb:4NYK|rcsb pdb:5WKU|rcsb pdb:5WKV|rcsb pdb:5WKX|rcsb pdb:5WKY|rcsb pdb:6AVE|rcsb pdb:6CMC|rcsb pdb:6VTK|rcsb pdb:6VTL|rcsb pdb:6X9H|reactome:R-GGA-2672351|refseq:NP_001035557.1|refseq:XP_015155720.1|refseq:XP_015155721.1|dip:DIP-59283N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031 rogid:LX7z/HLJnGeVgn3w5Z+Z9H4AMV49031 rigid:EfvUqVuFP+M1HaBwoRP7WURMwwI false sufficient binding region:14-463 sufficient binding region:14-463 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)