#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17693-4 uniprotkb:P17693-4 intact:EBI-16586442 intact:EBI-16586442 psi-mi:p17693-4(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G.3-5(isoform synonym)|uniprotkb:HLA-G4(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:p17693-4(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G.3-5(isoform synonym)|uniprotkb:HLA-G4(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484464|imex:IM-26243-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1043063(isoform-parent) intact:EBI-1043063(isoform-parent) - - - figure legend:2B|comment:"homodimers of HLA-G3 (alpha1 domain, lane 4) were never observed"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-m8)|taxid:9606(human M8 metastatic melanoma cell line) - 2017/07/19 2017/11/07 rogid:oqA22mMKs114iRAk3ZSY3S3+YoM9606 rogid:oqA22mMKs114iRAk3ZSY3S3+YoM9606 rigid:dgKrtJKPMfU+5YY3CLmuawaabDk false - - 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P17693-1 uniprotkb:P17693-1 intact:EBI-16586348|ensembl:ENSP00000353472|ensembl:ENSP00000373116|ensembl:ENSP00000388176|ensembl:ENSP00000389522|ensembl:ENSP00000398200|ensembl:ENSP00000405238|ensembl:ENSP00000408773|ensembl:ENSP00000412927|ensembl:ENSP00000447762|ensembl:ENSP00000447780|ensembl:ENSP00000448085|ensembl:ENSP00000448363|ensembl:ENSP00000449291|ensembl:ENSP00000449903 intact:EBI-16586348|ensembl:ENSP00000353472|ensembl:ENSP00000373116|ensembl:ENSP00000388176|ensembl:ENSP00000389522|ensembl:ENSP00000398200|ensembl:ENSP00000405238|ensembl:ENSP00000408773|ensembl:ENSP00000412927|ensembl:ENSP00000447762|ensembl:ENSP00000447780|ensembl:ENSP00000448085|ensembl:ENSP00000448363|ensembl:ENSP00000449291|ensembl:ENSP00000449903 psi-mi:p17693-1(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:p17693-1(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484467|imex:IM-26243-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000204632(gene)|ensembl:ENSG00000206506(gene)|ensembl:ENSG00000230413(gene)|ensembl:ENSG00000233095(gene)|ensembl:ENSG00000235346(gene)|ensembl:ENSG00000235680(gene)|ensembl:ENSG00000237216(gene)|ensembl:ENST00000360323(transcript)|ensembl:ENST00000383621(transcript)|ensembl:ENST00000423011(transcript)|ensembl:ENST00000423373(transcript)|ensembl:ENST00000428701(transcript)|ensembl:ENST00000428952(transcript)|ensembl:ENST00000444098(transcript)|ensembl:ENST00000449127(transcript)|ensembl:ENST00000546545(transcript)|ensembl:ENST00000546634(transcript)|ensembl:ENST00000547241(transcript)|ensembl:ENST00000547931(transcript)|ensembl:ENST00000550897(transcript)|ensembl:ENST00000553052(transcript)|intact:EBI-1043063(isoform-parent) ensembl:ENSG00000204632(gene)|ensembl:ENSG00000206506(gene)|ensembl:ENSG00000230413(gene)|ensembl:ENSG00000233095(gene)|ensembl:ENSG00000235346(gene)|ensembl:ENSG00000235680(gene)|ensembl:ENSG00000237216(gene)|ensembl:ENST00000360323(transcript)|ensembl:ENST00000383621(transcript)|ensembl:ENST00000423011(transcript)|ensembl:ENST00000423373(transcript)|ensembl:ENST00000428701(transcript)|ensembl:ENST00000428952(transcript)|ensembl:ENST00000444098(transcript)|ensembl:ENST00000449127(transcript)|ensembl:ENST00000546545(transcript)|ensembl:ENST00000546634(transcript)|ensembl:ENST00000547241(transcript)|ensembl:ENST00000547931(transcript)|ensembl:ENST00000550897(transcript)|ensembl:ENST00000553052(transcript)|intact:EBI-1043063(isoform-parent) intact:EBI-16586477(see-also) - - figure legend:2Bi|comment:"homodimers of HLA-G3 (alpha1 domain, lane 4) were never observed"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-m8)|taxid:9606(human M8 metastatic melanoma cell line) - 2017/07/19 2017/11/07 rogid:E3xsP+XcQvU64mCe/05DTS9vHQw9606 rogid:E3xsP+XcQvU64mCe/05DTS9vHQw9606 rigid:C3nsKWrdGAKdXkjO+Xiw8kRVuJE false - - 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P17693-2 uniprotkb:P17693-2 intact:EBI-16586375 intact:EBI-16586375 psi-mi:p17693-2(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G2(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:p17693-2(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G2(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484473|imex:IM-26243-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1043063(isoform-parent) intact:EBI-1043063(isoform-parent) - - - figure legend:2Bii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-m8)|taxid:9606(human M8 metastatic melanoma cell line) - 2017/07/19 2017/11/07 rogid:JSTy1tXCxydRc2vFZFvirfWyJN49606 rogid:JSTy1tXCxydRc2vFZFvirfWyJN49606 rigid:ioDbySK47LEexrR6uF3PgxPUJVo false - - 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P17693-5 uniprotkb:P17693-5 intact:EBI-16586455 intact:EBI-16586455 psi-mi:p17693-5(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1sol(isoform synonym)|uniprotkb:HLA-G5(isoform synonym)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short) psi-mi:p17693-5(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1sol(isoform synonym)|uniprotkb:HLA-G5(isoform synonym)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short) psi-mi:"MI:0982"(electrophoretic mobility-based method) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16586452|imex:IM-26243-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1043063(isoform-parent) intact:EBI-1043063(isoform-parent) - - - figure legend:2Bv|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-m8)|taxid:9606(human M8 metastatic melanoma cell line) - 2017/07/19 2017/11/07 rogid:HvexN+ptw40n+d9TEURiIrCMCNg9606 rogid:HvexN+ptw40n+d9TEURiIrCMCNg9606 rigid:baW4XI1a6fFT5Wo/rfP7MRcB3bY false - - 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N423 uniprotkb:P17693-1 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586348|ensembl:ENSP00000353472|ensembl:ENSP00000373116|ensembl:ENSP00000388176|ensembl:ENSP00000389522|ensembl:ENSP00000398200|ensembl:ENSP00000405238|ensembl:ENSP00000408773|ensembl:ENSP00000412927|ensembl:ENSP00000447762|ensembl:ENSP00000447780|ensembl:ENSP00000448085|ensembl:ENSP00000448363|ensembl:ENSP00000449291|ensembl:ENSP00000449903 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-1(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484542|imex:IM-26243-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 ensembl:ENSG00000204632(gene)|ensembl:ENSG00000206506(gene)|ensembl:ENSG00000230413(gene)|ensembl:ENSG00000233095(gene)|ensembl:ENSG00000235346(gene)|ensembl:ENSG00000235680(gene)|ensembl:ENSG00000237216(gene)|ensembl:ENST00000360323(transcript)|ensembl:ENST00000383621(transcript)|ensembl:ENST00000423011(transcript)|ensembl:ENST00000423373(transcript)|ensembl:ENST00000428701(transcript)|ensembl:ENST00000428952(transcript)|ensembl:ENST00000444098(transcript)|ensembl:ENST00000449127(transcript)|ensembl:ENST00000546545(transcript)|ensembl:ENST00000546634(transcript)|ensembl:ENST00000547241(transcript)|ensembl:ENST00000547931(transcript)|ensembl:ENST00000550897(transcript)|ensembl:ENST00000553052(transcript)|intact:EBI-1043063(isoform-parent) - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/15 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:E3xsP+XcQvU64mCe/05DTS9vHQw9606 rigid:yT+XLgcf3zp0zEFT9a+PU7aLgkI false fc-igg tag:?-?|sufficient binding region:24-458 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N423 uniprotkb:P17693-2 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586375 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-2(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G2(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484552|imex:IM-26243-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 intact:EBI-1043063(isoform-parent) - - - figure legend:3A-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/15 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:JSTy1tXCxydRc2vFZFvirfWyJN49606 rigid:GpThw5xZDM8xMeVBkbi72Mm13Ik false fc-igg tag:?-?|sufficient binding region:24-458 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N423 uniprotkb:P17693-5 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586455 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-5(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1sol(isoform synonym)|uniprotkb:HLA-G5(isoform synonym)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short) psi-mi:"MI:0004"(affinity chromatography technology) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16586538|imex:IM-26243-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 intact:EBI-1043063(isoform-parent) - - - figure legend:3A-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/07 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:HvexN+ptw40n+d9TEURiIrCMCNg9606 rigid:6q8IsOwc+0/62BbZgEVQnyzPpWI false sufficient binding region:24-458|fc-igg tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N423 uniprotkb:P17693-6 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586550 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-6(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G2sol(isoform synonym)|uniprotkb:HLA-G6(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16586544|imex:IM-26243-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 intact:EBI-1043063(isoform-parent) - - - figure legend:3A-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/07 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:HHPWxf3vTTEsOUupfF5cW9fCEjI9606 rigid:SURZBRyBLGYNochNQe2wGx0bA8c false fc-igg tag:?-?|sufficient binding region:24-458 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N423 uniprotkb:P17693-6 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586550 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-6(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G2sol(isoform synonym)|uniprotkb:HLA-G6(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0400"(affinity technology) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484595|imex:IM-26243-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 intact:EBI-1043063(isoform-parent) - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/15 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:HHPWxf3vTTEsOUupfF5cW9fCEjI9606 rigid:SURZBRyBLGYNochNQe2wGx0bA8c false fc-igg tag:?-?|sufficient binding region:24-458 glutathione s tranferase tag:n-n - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q8N423 uniprotkb:P17693-6 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586550 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-6(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G2sol(isoform synonym)|uniprotkb:HLA-G6(isoform synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484648|imex:IM-26243-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 intact:EBI-1043063(isoform-parent) - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/08 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:HHPWxf3vTTEsOUupfF5cW9fCEjI9606 rigid:SURZBRyBLGYNochNQe2wGx0bA8c false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q8N423 uniprotkb:P17693-5 intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373 intact:EBI-16586455 psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym) psi-mi:p17693-5(display_long)|uniprotkb:HLA G antigen(gene name synonym)|uniprotkb:MHC class I antigen G(gene name synonym)|uniprotkb:HLA-G1sol(isoform synonym)|uniprotkb:HLA-G5(isoform synonym)|uniprotkb:HLA-6.0(gene name synonym)|uniprotkb:HLAG(gene name synonym)|uniprotkb:HLA-G(gene name)|psi-mi:HLA-G(display_short) psi-mi:"MI:0054"(fluorescence-activated cell sorting) HoWangYin et al. (2012) pubmed:22802125|imex:IM-26243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-15484660|imex:IM-26243-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695 intact:EBI-1043063(isoform-parent) - - - figure legend:3Ci|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/19 2017/11/08 rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606 rogid:HvexN+ptw40n+d9TEURiIrCMCNg9606 rigid:6q8IsOwc+0/62BbZgEVQnyzPpWI false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)