#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32660	uniprotkb:P42838	intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W	intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W	psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym)	psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Puts et al. (2012)	pubmed:22791719|imex:IM-25646	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643543|imex:IM-25646-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)	refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695	-	crc64:3CC3FBA8ADDE8960	crc64:55BDA1F32251B4E6	figure legend:Fig. 1B, 2A, 8C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/08	2017/02/08	rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292	rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292	rigid:K113XbAj8d/ppcLMEzF12rkjy14	false	cub:?-?	mutation disrupting interaction strength:159-159|mutation disrupting interaction strength:216-216|nub:?-?|mutation disrupting interaction strength:83-83|mutation disrupting interaction strength:237-237|mutation disrupting interaction strength:375-375|mutation disrupting interaction strength:404-404|mutation disrupting interaction strength:110-110|mutation decreasing interaction strength:231-231	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25656	uniprotkb:P39524	intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W	intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C	psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short)	psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Puts et al. (2012)	pubmed:22791719|imex:IM-25646	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643579|imex:IM-25646-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656	refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837	-	crc64:565575CA402C0C91	crc64:5745B92901F8E1AE	figure legend:Fig. 2A, 2B, 4A, 4C, 6A, 8A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/08	2017/02/08	rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292	rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292	rigid:H/6/aNvfGyK1lAEOYrg5Yd83mgw	false	mutation disrupting interaction strength:80-80|mutation disrupting interaction strength:123-123|mutation decreasing interaction strength:176-176|mutation decreasing interaction strength:190-190|nub:?-?	cub:?-?|mutation with no effect:342-342|mutation disrupting interaction strength:560-560|mutation disrupting interaction strength:341-341	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53740	uniprotkb:Q12674	intact:EBI-28524|uniprotkb:D6W1M3|ensemblfungi:YNR048W	intact:EBI-3142|uniprotkb:D6VZY4|ensemblfungi:YMR162C	psi-mi:yn8s_yeast(display_long)|uniprotkb:CDC50/ROS3 family protein 1(gene name synonym)|uniprotkb:N3453(orf name)|uniprotkb:YNR048W(locus name)	psi-mi:atc8_yeast(display_long)|uniprotkb:DNF3(gene name)|psi-mi:DNF3(display_short)|uniprotkb:Aminophospholipid translocase(gene name synonym)|uniprotkb:Phospholipid translocase(gene name synonym)|uniprotkb:YM8520.11C(orf name)|uniprotkb:YMR162C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Puts et al. (2012)	pubmed:22791719|imex:IM-25646	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643595|imex:IM-25646-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005331|refseq:NP_014446.3|dip:DIP-1250N|reactome:R-SCE-6798695|ensemblfungi:YNR048W(gene)|ensemblfungi:YNR048W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)	refseq:NP_013885.1|sgd:S000004772|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR023299|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR018303|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR023214|interpro:IPR032630|interpro:IPR032631|interpro:IPR023298|interpro:IPR036412|ensemblfungi:YMR162C(gene)|ensemblfungi:YMR162C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|reactome:R-SCE-6798695|reactome:R-SCE-936837|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)	-	-	-	figure legend:Fig. 2A, 2B, 4A, 8B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/08	2017/02/08	rogid:MncHVMyjKiasqdyZuY2AXKeYuOE559292	rogid:ps8epWs4G79x44mlIQyoRIfpjFU559292	rigid:jLKsnZAj792qqvj86vo7KJnwMgA	false	mutation disrupting interaction strength:82-82|mutation disrupting interaction strength:126-126|mutation decreasing interaction strength:179-179|mutation decreasing interaction strength:193-193|nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32660	uniprotkb:P42838	intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W	intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W	psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym)	psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Puts et al. (2012)	pubmed:22791719|imex:IM-25646	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643643|imex:IM-25646-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)	refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695	-	crc64:3CC3FBA8ADDE8960	crc64:55BDA1F32251B4E6	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/08	2017/02/08	rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292	rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292	rigid:K113XbAj8d/ppcLMEzF12rkjy14	false	cub:?-?	nub:?-?|mutation disrupting interaction strength:83-83|mutation disrupting interaction strength:237-237|mutation disrupting interaction strength:375-375|mutation disrupting interaction strength:404-404|mutation decreasing interaction strength:65-65	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25656	uniprotkb:P39524	intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W	intact:EBI-3106|uniprotkb:D6VPJ2|ensemblfungi:YAL026C	psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short)	psi-mi:atc3_yeast(display_long)|uniprotkb:DRS2(gene name)|psi-mi:DRS2(display_short)|uniprotkb:FUN38(orf name)|uniprotkb:YAL026C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Puts et al. (2012)	pubmed:22791719|imex:IM-25646	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643670|imex:IM-25646-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656	refseq:NP_009376.2|sgd:S000000024|dip:DIP-2216N|mint:P39524|ensemblfungi:YAL026C(gene)|ensemblfungi:YAL026C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6PSX|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH5|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|reactome:R-SCE-936837	-	crc64:565575CA402C0C91	crc64:5745B92901F8E1AE	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/08	2017/02/08	rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292	rogid:qJ8uK7dznIqyjVwjbw/VGn5Bo+4559292	rigid:H/6/aNvfGyK1lAEOYrg5Yd83mgw	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53740	uniprotkb:Q12674	intact:EBI-28524|uniprotkb:D6W1M3|ensemblfungi:YNR048W	intact:EBI-3142|uniprotkb:D6VZY4|ensemblfungi:YMR162C	psi-mi:yn8s_yeast(display_long)|uniprotkb:CDC50/ROS3 family protein 1(gene name synonym)|uniprotkb:N3453(orf name)|uniprotkb:YNR048W(locus name)	psi-mi:atc8_yeast(display_long)|uniprotkb:DNF3(gene name)|psi-mi:DNF3(display_short)|uniprotkb:Aminophospholipid translocase(gene name synonym)|uniprotkb:Phospholipid translocase(gene name synonym)|uniprotkb:YM8520.11C(orf name)|uniprotkb:YMR162C(locus name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Puts et al. (2012)	pubmed:22791719|imex:IM-25646	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13643662|imex:IM-25646-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005331|refseq:NP_014446.3|dip:DIP-1250N|reactome:R-SCE-6798695|ensemblfungi:YNR048W(gene)|ensemblfungi:YNR048W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)	refseq:NP_013885.1|sgd:S000004772|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR023299|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR018303|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR023214|interpro:IPR032630|interpro:IPR032631|interpro:IPR023298|interpro:IPR036412|ensemblfungi:YMR162C(gene)|ensemblfungi:YMR162C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|reactome:R-SCE-6798695|reactome:R-SCE-936837|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/08	2017/02/08	rogid:MncHVMyjKiasqdyZuY2AXKeYuOE559292	rogid:ps8epWs4G79x44mlIQyoRIfpjFU559292	rigid:jLKsnZAj792qqvj86vo7KJnwMgA	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)