#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8R4D5	uniprotkb:P21279	intact:EBI-15993468|ensembl:ENSMUSP00000036991|ensembl:ENSMUSP00000108739|ensembl:ENSMUSP00000131209|uniprotkb:E9Q165|uniprotkb:Q148W9	intact:EBI-771975|uniprotkb:Q6PFF5|ensembl:ENSMUSP00000025541	psi-mi:trpm8_mouse(display_long)|uniprotkb:Trpm8(gene name)|psi-mi:Trpm8(display_short)|uniprotkb:Ltrpc6(gene name synonym)|uniprotkb:Trpp8(gene name synonym)|uniprotkb:Long transient receptor potential channel 6(gene name synonym)|uniprotkb:Transient receptor potential p8(gene name synonym)	psi-mi:gnaq_mouse(display_long)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2012)	pubmed:22750945|doi:10.1038/ncb2529|imex:IM-25172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993510|imex:IM-25172-1|dip:DIP-200625E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000036251(gene)|ensembl:ENSMUST00000040210(transcript)|ensembl:ENSMUST00000113114(transcript)|ensembl:ENSMUST00000171176(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050955"(thermoception)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR029603|interpro:IPR041491|reactome:R-MMU-3295583|refseq:NP_599013.1|refseq:XP_006529288.1|refseq:XP_006529289.1|dip:DIP-61852N	refseq:NP_032165.3|dip:DIP-606N|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P21279|rcsb pdb:2BCJ|rcsb pdb:2RGN|rcsb pdb:3AH8|rcsb pdb:3OHM|rcsb pdb:4EKC|rcsb pdb:4EKD|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|rcsb pdb:5DO9|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|go:"GO:0044297"(cell body)|ensembl:ENSMUSG00000024639(gene)|ensembl:ENSMUST00000025541(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:UeD7NXsy7aPVJx6McYvIT9G4Lho10090	rogid:7HfYjIynxSexMzn1uUS6x4sfzbI10090	rigid:wJsHm7rInuJ1XLEIqwAXL9zSqCY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8R455	uniprotkb:P50148	intact:EBI-15993527|ensembl:ENSRNOP00000025879	intact:EBI-3909604|uniprotkb:Q6NT27|uniprotkb:Q92471|uniprotkb:O15108|uniprotkb:Q9BZB9|uniprotkb:Q13462|ensembl:ENSP00000286548	psi-mi:trpm8_rat(display_long)|uniprotkb:Trpm8(gene name)|psi-mi:Trpm8(display_short)|uniprotkb:Cmr1(gene name synonym)|uniprotkb:Cold menthol receptor 1(gene name synonym)	psi-mi:gnaq_human(display_long)|uniprotkb:GNAQ(gene name)|psi-mi:GNAQ(display_short)|uniprotkb:GAQ(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2012)	pubmed:22750945|doi:10.1038/ncb2529|imex:IM-25172	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993574|imex:IM-25172-3|dip:DIP-200626E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019035(gene)|ensembl:ENSRNOT00000025879(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050955"(thermoception)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR029603|interpro:IPR041491|reactome:R-RNO-3295583|refseq:NP_599198.2|rgd:620762|dip:DIP-61851N	refseq:NP_002063.2|ensembl:ENSG00000156052(gene)|ensembl:ENST00000286548(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P50148|rcsb pdb:6VU5|reactome:R-HSA-112043|reactome:R-HSA-202040|reactome:R-HSA-399997|reactome:R-HSA-416476|reactome:R-HSA-418592|reactome:R-HSA-428930|reactome:R-HSA-434316|reactome:R-HSA-456926|reactome:R-HSA-6814122|dip:DIP-41652N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:ycHV+ayhFtGImZChGM2vZMauvPY10116	rogid:ExDRSmmaTXllLWSDrc79rkxxAqQ9606	rigid:FdoKPTNVI8OcXGnjEl02D7dE7Uc	false	sufficient binding region:1-691|sufficient binding region:980-1104|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R455	uniprotkb:P50148	intact:EBI-15993527|ensembl:ENSRNOP00000025879	intact:EBI-3909604|uniprotkb:Q6NT27|uniprotkb:Q92471|uniprotkb:O15108|uniprotkb:Q9BZB9|uniprotkb:Q13462|ensembl:ENSP00000286548	psi-mi:trpm8_rat(display_long)|uniprotkb:Trpm8(gene name)|psi-mi:Trpm8(display_short)|uniprotkb:Cmr1(gene name synonym)|uniprotkb:Cold menthol receptor 1(gene name synonym)	psi-mi:gnaq_human(display_long)|uniprotkb:GNAQ(gene name)|psi-mi:GNAQ(display_short)|uniprotkb:GAQ(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zhang et al. (2012)	pubmed:22750945|doi:10.1038/ncb2529|imex:IM-25172	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993597|imex:IM-25172-4|dip:DIP-200626E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019035(gene)|ensembl:ENSRNOT00000025879(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050955"(thermoception)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR029603|interpro:IPR041491|reactome:R-RNO-3295583|refseq:NP_599198.2|rgd:620762|dip:DIP-61851N	refseq:NP_002063.2|ensembl:ENSG00000156052(gene)|ensembl:ENST00000286548(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P50148|rcsb pdb:6VU5|reactome:R-HSA-112043|reactome:R-HSA-202040|reactome:R-HSA-399997|reactome:R-HSA-416476|reactome:R-HSA-418592|reactome:R-HSA-428930|reactome:R-HSA-434316|reactome:R-HSA-456926|reactome:R-HSA-6814122|dip:DIP-41652N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ycHV+ayhFtGImZChGM2vZMauvPY10116	rogid:ExDRSmmaTXllLWSDrc79rkxxAqQ9606	rigid:FdoKPTNVI8OcXGnjEl02D7dE7Uc	false	v5 tag:c-c|his tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R455	uniprotkb:P50148	intact:EBI-15993527|ensembl:ENSRNOP00000025879	intact:EBI-3909604|uniprotkb:Q6NT27|uniprotkb:Q92471|uniprotkb:O15108|uniprotkb:Q9BZB9|uniprotkb:Q13462|ensembl:ENSP00000286548	psi-mi:trpm8_rat(display_long)|uniprotkb:Trpm8(gene name)|psi-mi:Trpm8(display_short)|uniprotkb:Cmr1(gene name synonym)|uniprotkb:Cold menthol receptor 1(gene name synonym)	psi-mi:gnaq_human(display_long)|uniprotkb:GNAQ(gene name)|psi-mi:GNAQ(display_short)|uniprotkb:GAQ(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2012)	pubmed:22750945|doi:10.1038/ncb2529|imex:IM-25172	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993555|imex:IM-25172-2|dip:DIP-200626E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019035(gene)|ensembl:ENSRNOT00000025879(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050955"(thermoception)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR029603|interpro:IPR041491|reactome:R-RNO-3295583|refseq:NP_599198.2|rgd:620762|dip:DIP-61851N	refseq:NP_002063.2|ensembl:ENSG00000156052(gene)|ensembl:ENST00000286548(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P50148|rcsb pdb:6VU5|reactome:R-HSA-112043|reactome:R-HSA-202040|reactome:R-HSA-399997|reactome:R-HSA-416476|reactome:R-HSA-418592|reactome:R-HSA-428930|reactome:R-HSA-434316|reactome:R-HSA-456926|reactome:R-HSA-6814122|dip:DIP-41652N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ycHV+ayhFtGImZChGM2vZMauvPY10116	rogid:ExDRSmmaTXllLWSDrc79rkxxAqQ9606	rigid:FdoKPTNVI8OcXGnjEl02D7dE7Uc	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R455	uniprotkb:P50148	intact:EBI-15993527|ensembl:ENSRNOP00000025879	intact:EBI-3909604|uniprotkb:Q6NT27|uniprotkb:Q92471|uniprotkb:O15108|uniprotkb:Q9BZB9|uniprotkb:Q13462|ensembl:ENSP00000286548	psi-mi:trpm8_rat(display_long)|uniprotkb:Trpm8(gene name)|psi-mi:Trpm8(display_short)|uniprotkb:Cmr1(gene name synonym)|uniprotkb:Cold menthol receptor 1(gene name synonym)	psi-mi:gnaq_human(display_long)|uniprotkb:GNAQ(gene name)|psi-mi:GNAQ(display_short)|uniprotkb:GAQ(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhang et al. (2012)	pubmed:22750945|doi:10.1038/ncb2529|imex:IM-25172	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15993619|imex:IM-25172-5|dip:DIP-200626E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019035(gene)|ensembl:ENSRNOT00000025879(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050955"(thermoception)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR029603|interpro:IPR041491|reactome:R-RNO-3295583|refseq:NP_599198.2|rgd:620762|dip:DIP-61851N	refseq:NP_002063.2|ensembl:ENSG00000156052(gene)|ensembl:ENST00000286548(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P50148|rcsb pdb:6VU5|reactome:R-HSA-112043|reactome:R-HSA-202040|reactome:R-HSA-399997|reactome:R-HSA-416476|reactome:R-HSA-418592|reactome:R-HSA-428930|reactome:R-HSA-434316|reactome:R-HSA-456926|reactome:R-HSA-6814122|dip:DIP-41652N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ycHV+ayhFtGImZChGM2vZMauvPY10116	rogid:ExDRSmmaTXllLWSDrc79rkxxAqQ9606	rigid:FdoKPTNVI8OcXGnjEl02D7dE7Uc	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)