#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q90VU7 uniprotkb:P35585 intact:EBI-7460704|intact:MINT-5281653 intact:EBI-1040251|ensembl:ENSMUSP00000003117 psi-mi:q90vu7_9hiv1(display_long)|uniprotkb:nef(gene name)|psi-mi:nef(display_short)|uniprotkb:3'ORF(gene name synonym)|uniprotkb:Negative factor(gene name synonym) psi-mi:ap1m1_mouse(display_long)|uniprotkb:Ap1m1(gene name)|psi-mi:Ap1m1(display_short)|uniprotkb:Cltnm(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Jia et al. (2012) pubmed:22705789|doi:10.1038/nsmb.2328|imex:IM-18553 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15988092|imex:IM-18553-1|dip:DIP-189977E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019058"(viral life cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0045225"(negative regulation of CD4 production)|go:"GO:0046776"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051117"(ATPase binding)|go:"GO:0052085"(suppression by symbiont of host T-cell mediated immune response)|go:"GO:0075528"(modulation by virus of host immune response)|interpro:IPR001558(HIV negative factor Nef)|interpro:IPR027480|interpro:IPR027481|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:6CM9|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|dip:DIP-43762N|mint:Q90VU7 refseq:NP_031482.1|ensembl:ENSMUSG00000003033(gene)|ensembl:ENSMUST00000003117(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:P35585|rcsb pdb:1W63|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-6798695|dip:DIP-35323N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/q84A6o2nxh3A2gNX5BJ1TL+Ids11676 rogid:jng3stxfxbi8Emuhlquac0/JC0Q10090 rigid:43SkW9dmL/aLYA3qTF4Uo79UpWU false maltose binding protein tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)