#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O94751	uniprotkb:O94751	intact:EBI-1002539|ensemblfungi:"SPCC1322.12c.1:pep"	intact:EBI-1002539|ensemblfungi:"SPCC1322.12c.1:pep"	psi-mi:bub1_schpo(display_long)|uniprotkb:bub1(gene name)|psi-mi:bub1(display_short)|uniprotkb:SPCC1322.12c(orf name)	psi-mi:bub1_schpo(display_long)|uniprotkb:bub1(gene name)|psi-mi:bub1(display_short)|uniprotkb:SPCC1322.12c(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986681|imex:IM-25168-2|dip:DIP-200609E	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588140.1|ensemblfungi:SPCC1322.12c(gene)|ensemblfungi:SPCC1322.12c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|dip:DIP-37961N|reactome:R-SPO-141430	refseq:NP_588140.1|ensemblfungi:SPCC1322.12c(gene)|ensemblfungi:SPCC1322.12c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|dip:DIP-37961N|reactome:R-SPO-141430	psi-mi:"MI:0465"(dip)	crc64:32CE71E471BC1BF6	crc64:32CE71E471BC1BF6	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:J8w0DbD6VYbjMYx1+NCbEol2Jhw284812	rogid:J8w0DbD6VYbjMYx1+NCbEol2Jhw284812	rigid:ass//hiUuyWJruQTKTmXhmyaUmI	false	sufficient binding region:631-1044	sufficient binding region:631-1044	-	0	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8NG31	uniprotkb:O43683	intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463	intact:EBI-748936|uniprotkb:O43430|uniprotkb:O43643|uniprotkb:O60626|uniprotkb:Q53QE4|intact:EBI-10974242|uniprotkb:E9PC26|uniprotkb:F5GXI5|intact:EBI-28974347|ensembl:ENSP00000302530	psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym)	psi-mi:bub1_human(display_long)|uniprotkb:BUB1A(gene name synonym)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short)|uniprotkb:BUB1L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986664|imex:IM-25168-1|dip:DIP-102567E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N	ensembl:ENSP00000302530|ensembl:ENST00000409311|ensembl:ENSP00000386701|ensembl:ENST00000535254|ensembl:ENSP00000441013|refseq:NP_004327.1|refseq:NP_001265546.1|ensembl:ENSG00000169679(gene)|ensembl:ENST00000302759(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43683|rcsb pdb:2LAH|rcsb pdb:4A1G|rcsb pdb:4QPM|rcsb pdb:4R8Q|rcsb pdb:5DMZ|rcsb pdb:6F7B|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-24206N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606	rogid:hsbJZRz5kXxVI+ADgSaCoUfXE1o9606	rigid:xUxpkASHuE2mS52e9rX+r5io4lE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O59757	uniprotkb:O94751	intact:EBI-1002205|ensemblfungi:"SPCC1020.02.1:pep"	intact:EBI-1002539|ensemblfungi:"SPCC1322.12c.1:pep"	psi-mi:spc7_schpo(display_long)|uniprotkb:NMS complex subunit spc7(gene name synonym)|uniprotkb:spc7(gene name)|psi-mi:spc7(display_short)|uniprotkb:SPCC1020.02(orf name)	psi-mi:bub1_schpo(display_long)|uniprotkb:bub1(gene name)|psi-mi:bub1(display_short)|uniprotkb:SPCC1322.12c(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986699|imex:IM-25168-3|dip:DIP-200611E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_587958.1|ensemblfungi:SPCC1020.02(gene)|ensemblfungi:SPCC1020.02.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031617"(NMS complex)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0140483"(kinetochore adaptor activity)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR013253(Kinetochore Spc7)|interpro:IPR028972|interpro:IPR033338|dip:DIP-35340N	refseq:NP_588140.1|ensemblfungi:SPCC1322.12c(gene)|ensemblfungi:SPCC1322.12c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|dip:DIP-37961N|reactome:R-SPO-141430	psi-mi:"MI:0465"(dip)	crc64:829312F81FFB7502	crc64:32CE71E471BC1BF6	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VRbEqZgOMYnun+O/YUx95kWsxFM284812	rogid:J8w0DbD6VYbjMYx1+NCbEol2Jhw284812	rigid:ueyI+UrrXpWBAkSK0zNIH+HhbMM	false	flag tag:c-c|mutation:77-77,552-552,529-529,507-507,453-453,422-422,413-413,395-395,366-366,338-338,257-257,221-221	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O59757	uniprotkb:O42860	intact:EBI-1002205|ensemblfungi:"SPCC1020.02.1:pep"	intact:EBI-1269300|ensemblfungi:"SPAC23H3.08c.1:pep"	psi-mi:spc7_schpo(display_long)|uniprotkb:NMS complex subunit spc7(gene name synonym)|uniprotkb:spc7(gene name)|psi-mi:spc7(display_short)|uniprotkb:SPCC1020.02(orf name)	psi-mi:bub3_schpo(display_long)|uniprotkb:bub3(gene name)|psi-mi:bub3(display_short)|uniprotkb:SPAC23H3.08c(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986699|imex:IM-25168-3|dip:DIP-200611E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_587958.1|ensemblfungi:SPCC1020.02(gene)|ensemblfungi:SPCC1020.02.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031617"(NMS complex)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0140483"(kinetochore adaptor activity)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR013253(Kinetochore Spc7)|interpro:IPR028972|interpro:IPR033338|dip:DIP-35340N	refseq:NP_593798.1|dip:DIP-39398N|ensemblfungi:SPAC23H3.08c(gene)|ensemblfungi:SPAC23H3.08c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0140499"(negative regulation of mitotic spindle assembly checkpoint signaling)|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990942"(mitotic metaphase chromosome recapture)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-SPO-141430	psi-mi:"MI:0465"(dip)	crc64:829312F81FFB7502	crc64:A5028C58CEBEED43	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VRbEqZgOMYnun+O/YUx95kWsxFM284812	rogid:d49VS+Ae+bNnSiMwJOrUy1NFKFs284812	rigid:ueyI+UrrXpWBAkSK0zNIH+HhbMM	false	flag tag:c-c|mutation:77-77,552-552,529-529,507-507,453-453,422-422,413-413,395-395,366-366,338-338,257-257,221-221	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94751	uniprotkb:O42860	intact:EBI-1002539|ensemblfungi:"SPCC1322.12c.1:pep"	intact:EBI-1269300|ensemblfungi:"SPAC23H3.08c.1:pep"	psi-mi:bub1_schpo(display_long)|uniprotkb:bub1(gene name)|psi-mi:bub1(display_short)|uniprotkb:SPCC1322.12c(orf name)	psi-mi:bub3_schpo(display_long)|uniprotkb:bub3(gene name)|psi-mi:bub3(display_short)|uniprotkb:SPAC23H3.08c(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986813|imex:IM-25168-5|dip:DIP-200610E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588140.1|ensemblfungi:SPCC1322.12c(gene)|ensemblfungi:SPCC1322.12c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|dip:DIP-37961N|reactome:R-SPO-141430	refseq:NP_593798.1|dip:DIP-39398N|ensemblfungi:SPAC23H3.08c(gene)|ensemblfungi:SPAC23H3.08c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0140499"(negative regulation of mitotic spindle assembly checkpoint signaling)|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990942"(mitotic metaphase chromosome recapture)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-SPO-141430	psi-mi:"MI:0465"(dip)	crc64:32CE71E471BC1BF6	crc64:A5028C58CEBEED43	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:J8w0DbD6VYbjMYx1+NCbEol2Jhw284812	rogid:d49VS+Ae+bNnSiMwJOrUy1NFKFs284812	rigid:3ikpxdOrI+IvTSpg7DnfjU0cEyU	false	myc tag:c-c	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O59757	uniprotkb:O94235	intact:EBI-1002205|ensemblfungi:"SPCC1020.02.1:pep"	intact:EBI-15986737|ensemblfungi:"SPBC106.01.1:pep"|uniprotkb:Q9P7Z5|uniprotkb:Q9URW0	psi-mi:spc7_schpo(display_long)|uniprotkb:NMS complex subunit spc7(gene name synonym)|uniprotkb:spc7(gene name)|psi-mi:spc7(display_short)|uniprotkb:SPCC1020.02(orf name)	psi-mi:mph1l_schpo(display_long)|uniprotkb:mph1(gene name)|psi-mi:mph1(display_short)|uniprotkb:SPBC106.01(orf name)|uniprotkb:SPBC1271.16c(orf name)|uniprotkb:SPBC243.01(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986772|imex:IM-25168-4|dip:DIP-200608E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_587958.1|ensemblfungi:SPCC1020.02(gene)|ensemblfungi:SPCC1020.02.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031617"(NMS complex)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0140483"(kinetochore adaptor activity)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR013253(Kinetochore Spc7)|interpro:IPR028972|interpro:IPR033338|dip:DIP-35340N	ensemblfungi:SPBC106.01(gene)|ensemblfungi:SPBC106.01.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007127"(meiosis I)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051304"(chromosome separation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|dip:DIP-61850N|refseq:NP_595150.2	psi-mi:"MI:0465"(dip)	crc64:829312F81FFB7502	crc64:C943950DE001E8E3	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VRbEqZgOMYnun+O/YUx95kWsxFM284812	rogid:IPMt92USAGWr0i7NWEFObUGsxS8284812	rigid:nAKSYwmH17xLQivsO1LmZhEH3ew	false	sufficient binding region:1-100|sufficient binding region:331-436|sufficient binding region:531-877|O-phospho-L-threonine:257-257|mutation disrupting interaction rate:77-77,422-422,413-413,395-395,366-366,338-338,257-257,221-221|mutation disrupting interaction rate:552-552,529-529,507-507,453-453	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8NG31-2	uniprotkb:P33981-1	intact:EBI-10973816|ensembl:ENSP00000382576	intact:EBI-15986834|ensembl:ENSP00000358813	psi-mi:q8ng31-2(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym)	psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Yamagishi et al. (2012)	pubmed:22660415|doi:10.1038/ncb2515|imex:IM-25168	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15986843|imex:IM-25168-6|dip:DIP-200612E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137812(gene)|ensembl:ENST00000399668(transcript)|intact:EBI-1001161(isoform-parent)|uniprotkb:Q8NG31-2(isoform-parent)	intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:a+zajVOwKkY0QIqgiM6NOSUzqqY9606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rigid:7UzsuY10WvMTC/wv2Cho3EClUMs	false	sufficient binding region:728-999|sufficient binding region:1000-1199|mutation disrupting interaction rate:875-875|mutation disrupting interaction rate:1167-1167,1154-1154,1129-1129,1089-1089,1075-1075,1037-1037,1022-1022	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)