#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12038 uniprotkb:P40073 intact:EBI-17573|uniprotkb:D6W442|ensemblfungi:YPR032W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:sro7_yeast(display_long)|uniprotkb:SRO7(gene name)|psi-mi:SRO7(display_short)|uniprotkb:SNI1(gene name synonym)|uniprotkb:YPR032W(locus name)|uniprotkb:YP9367.12(orf name)|uniprotkb:SOP1(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 7(gene name synonym)|uniprotkb:Polarity protein SRO7(gene name synonym)|uniprotkb:Sodium protection protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061294|imex:IM-25746-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015357.1|sgd:S000006236|ensemblfungi:YPR032W(gene)|ensemblfungi:YPR032W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR036322|rcsb pdb:2OAJ|dip:DIP-2581N|mint:Q12038 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:FFB0901883009815 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:3nYgL2CW3rzKE71MX0MekJKKUlk559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:05I+kBmJEaWRN8u912Zn/5YlRHw false nub:n-n necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29465 uniprotkb:P40073 intact:EBI-4632|uniprotkb:D6VQ25|ensemblfungi:YBR023C intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:chs3_yeast(display_long)|uniprotkb:CHS3(gene name)|psi-mi:CHS3(display_short)|uniprotkb:CAL1(gene name synonym)|uniprotkb:DIT101(gene name synonym)|uniprotkb:KIT2(gene name synonym)|uniprotkb:YBR023C(locus name)|uniprotkb:CSD2(gene name synonym)|uniprotkb:YBR0305(orf name)|uniprotkb:Chitin-UDP acetyl-glucosaminyl transferase 3(gene name synonym)|uniprotkb:Class-IV chitin synthase 3(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061306|imex:IM-25746-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009579.1|sgd:S000000227|dip:DIP-2482N|mint:P29465|ensemblfungi:YBR023C(gene)|ensemblfungi:YBR023C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0004100"(chitin synthase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030428"(cell septum)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043332"(mating projection tip)|go:"GO:0045009"(chitosome)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR004835(Fungal chitin synthase)|interpro:IPR029044|rcsb pdb:4WJW refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - - crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:8Ik0u35UXSJVtqfgNdo49J+nzFk559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:cLxPYk4jytkkD/RTheQ2YVJfC6o false nub:n-n necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07533 uniprotkb:P40073 intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061317|imex:IM-25746-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:A1B7FD5B7076EC7F crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:xNIicScWjaxzhFZD2aeUFnD1xmY false nub:n-n|sufficient binding region:69-885 necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05080 uniprotkb:P40073 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061332|imex:IM-25746-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:AE4A76C2F4043021 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:1cjXbr2jPvV+5KAHUgEDUWsNy/M false nub:n-n|sufficient binding region:98-669 necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40073 uniprotkb:P40073 intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061343|imex:IM-25746-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:E467A4D50AA3EDB6 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:Ss8AK4xiNtTzEUsEQFI05XO981M false nub:n-n necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21339 uniprotkb:P40073 intact:EBI-11322|uniprotkb:D6W2P4|ensemblfungi:YOR188W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:msb1_yeast(display_long)|uniprotkb:MSB1(gene name)|psi-mi:MSB1(display_short)|uniprotkb:Multicopy suppressor of bud emergence 1(gene name synonym)|uniprotkb:YOR188W(locus name) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061354|imex:IM-25746-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR188W(gene)|ensemblfungi:YOR188W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030010"(establishment of cell polarity)|interpro:IPR012965(Protein of unknown function DUF1708)|interpro:IPR037508|refseq:NP_014831.3|sgd:S000005714|mint:P21339|dip:DIP-2687N refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - - crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:Lr2m/jqphbBj6HY6WgXvZzMFr+o559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:d/r71echV35ledF3hFVYqHfcKY8 false nub:n-n necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53901 uniprotkb:P40073 intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061372|imex:IM-25746-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - - crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:EYW4YcsprPQNQS1+4LRuZdu07Zk false nub:n-n necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08018 uniprotkb:P40073 intact:EBI-12972|uniprotkb:D6VW57|ensemblfungi:YJL128C intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:pbs2_yeast(display_long)|uniprotkb:PBS2(gene name)|psi-mi:PBS2(display_short)|uniprotkb:HOG4(gene name synonym)|uniprotkb:SFS4(gene name synonym)|uniprotkb:SSK4(gene name synonym)|uniprotkb:YJL128C(locus name)|uniprotkb:J0699(orf name)|uniprotkb:Polymyxin B resistance protein 2(gene name synonym)|uniprotkb:Suppressor of fluoride sensitivity 4(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061383|imex:IM-25746-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012407.2|sgd:S000003664|go:"GO:0031416"(NatB complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2VKN|reactome:R-SCE-168638|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450302|reactome:R-SCE-450321|reactome:R-SCE-6811555|go:"GO:0010494"(cytoplasmic stress granule)|ensemblfungi:YJL128C(gene)|ensemblfungi:YJL128C_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|mint:P08018|dip:DIP-2368N refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:9BC3435BDAFE8019 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1A, 4A, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:8kVv+9++58zg4knrpUYi+uGfLK8559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:Ggx8tZbYSAt8MzKGTpAbD3XBwzw false nub:n-n necessary binding region:298-367(IPR001452)|cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53901 uniprotkb:Q05080 intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061394|imex:IM-25746-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 - - crc64:AE4A76C2F4043021 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rigid:f/KeWAv8P1AUljRpxzRJjY7gtMo false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32457 uniprotkb:Q05080 intact:EBI-4429|uniprotkb:Q06161|uniprotkb:D6VYV8|ensemblfungi:YLR314C intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:cdc3_yeast(display_long)|uniprotkb:CDC3(gene name)|psi-mi:CDC3(display_short)|uniprotkb:L8543.7(orf name)|uniprotkb:YLR314C(locus name) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061405|imex:IM-25746-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013418.2|sgd:S000004306|dip:DIP-3010N|mint:P32457|ensemblfungi:YLR314C(gene)|ensemblfungi:YLR314C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000921"(septin ring assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0031107"(septin ring disassembly)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0034613"(cellular protein localization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|reactome:R-SCE-111457 refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 - crc64:DCCD4C8C16AA5E25 crc64:AE4A76C2F4043021 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:jAA171eszgeW4JEqIrAR4gJzTm4559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rigid:ugpC3WrtZ7Ojv2Tj6vUyXfeWiwg false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07533 uniprotkb:Q05080 intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061413|imex:IM-25746-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 - crc64:A1B7FD5B7076EC7F crc64:AE4A76C2F4043021 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rigid:mNvH3Tz4CiqcNW0P2zfWE7t/c5Y false nub:n-n|sufficient binding region:69-885 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08229 uniprotkb:Q05080 intact:EBI-36841|uniprotkb:D6W1Z7|ensemblfungi:YOL070C intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:nba1_yeast(display_long)|uniprotkb:YOL070C(locus name)|uniprotkb:NBA1(gene name)|psi-mi:NBA1(display_short)|uniprotkb:NAP1 and bud neck-associated protein 1(gene name synonym) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061421|imex:IM-25746-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005431|refseq:NP_014571.1|mint:Q08229|dip:DIP-1680N|ensemblfungi:YOL070C(gene)|ensemblfungi:YOL070C_mRNA(transcript)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0032153"(cell division site)|go:"GO:0032174"(cellular bud neck septin collar)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0045184"(establishment of protein localization)|go:"GO:1901900"(regulation of protein localization to cell division site)|go:"GO:2001107"(negative regulation of Rho guanyl-nucleotide exchange factor activity) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 - crc64:8128246D00B9C03D crc64:AE4A76C2F4043021 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:luFf7ztM7PzLgXJPbQlP9xaFT88559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rigid:CGOUql39HPVaEuqxNxbpTgoAU6k false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05080 uniprotkb:P53901 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061431|imex:IM-25746-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 - crc64:AE4A76C2F4043021 - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rigid:f/KeWAv8P1AUljRpxzRJjY7gtMo false nub:n-n|sufficient binding region:98-669 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00684 uniprotkb:P53901 intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name) psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061443|imex:IM-25746-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128 refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 - crc64:4EB3985DFA3FD823 - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rigid:nwYqHP5iUgRqF+giuqNgwph83Mw false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50623 uniprotkb:P53901 intact:EBI-19760|uniprotkb:D6VRT3|ensemblfungi:YDL064W intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W psi-mi:ubc9_yeast(display_long)|uniprotkb:UBC9(gene name)|psi-mi:UBC9(display_short)|uniprotkb:Ubiquitin-conjugating enzyme E2-18 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:YDL064W(locus name)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061453|imex:IM-25746-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010219.1|sgd:S000002222|reactome:R-SCE-3065678|reactome:R-SCE-3108214|reactome:R-SCE-3232118|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-4085377|ensemblfungi:YDL064W(gene)|ensemblfungi:YDL064W_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR027230|rcsb pdb:2EKE|rcsb pdb:2GJD|rcsb pdb:3ONG|rcsb pdb:5JNE|rcsb pdb:6Q83|dip:DIP-1531N|reactome:R-SCE-4551638|reactome:R-SCE-3899300|reactome:R-SCE-3108232|reactome:R-SCE-9615933 refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 - crc64:D74EE9845BB677B4 - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:mTdEVn/bucUQ/kuDsh7UseB9S70559292 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rigid:RpDMc7TFsVjl0vQOyJJnlnnGs8g false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32790 uniprotkb:P53901 intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short) psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061461|imex:IM-25746-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790 refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 - crc64:7FD85AA776407624 - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rigid:IU+tQPJkiyqFT5T0KJufPoTPnfQ false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05080 uniprotkb:Q07533 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061469|imex:IM-25746-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 - crc64:AE4A76C2F4043021 crc64:A1B7FD5B7076EC7F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rigid:mNvH3Tz4CiqcNW0P2zfWE7t/c5Y false nub:n-n|sufficient binding region:98-669 cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06244 uniprotkb:Q07533 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061477|imex:IM-25746-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 - crc64:D4E5C30D7F11458B crc64:A1B7FD5B7076EC7F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rigid:iyg9ZAorgyf5nIDJzINGcJnhbXY false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P27637 uniprotkb:Q07533 intact:EBI-20747|uniprotkb:D6VPM3|ensemblfungi:YAR014C intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W psi-mi:bud14_yeast(display_long)|uniprotkb:FUN2(orf name)|uniprotkb:YAR014C(locus name)|uniprotkb:BUD14(gene name)|psi-mi:BUD14(display_short) psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061485|imex:IM-25746-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009408.3|sgd:S000000069|mint:P27637|ensemblfungi:YAR014C(gene)|ensemblfungi:YAR014C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|dip:DIP-1756N refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 - crc64:F123511A4C592EB4 crc64:A1B7FD5B7076EC7F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:U/J6oV49Yml8AtGtqzZVi5WjZqc559292 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rigid:XNzY4xtqVoSyrVFXFMNXZrJVBkA false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08229 uniprotkb:Q07533 intact:EBI-36841|uniprotkb:D6W1Z7|ensemblfungi:YOL070C intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W psi-mi:nba1_yeast(display_long)|uniprotkb:YOL070C(locus name)|uniprotkb:NBA1(gene name)|psi-mi:NBA1(display_short)|uniprotkb:NAP1 and bud neck-associated protein 1(gene name synonym) psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061493|imex:IM-25746-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005431|refseq:NP_014571.1|mint:Q08229|dip:DIP-1680N|ensemblfungi:YOL070C(gene)|ensemblfungi:YOL070C_mRNA(transcript)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0032153"(cell division site)|go:"GO:0032174"(cellular bud neck septin collar)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0045184"(establishment of protein localization)|go:"GO:1901900"(regulation of protein localization to cell division site)|go:"GO:2001107"(negative regulation of Rho guanyl-nucleotide exchange factor activity) refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 - crc64:8128246D00B9C03D crc64:A1B7FD5B7076EC7F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:luFf7ztM7PzLgXJPbQlP9xaFT88559292 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rigid:UCt1kLH5bYxaVdkhJ1jmt+aTpwE false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53901 uniprotkb:Q07533 intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061501|imex:IM-25746-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 - - crc64:A1B7FD5B7076EC7F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rigid:HM7UGlnSg4bGSEs3KU9pdqMSLQY false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00772 uniprotkb:Q07533 intact:EBI-17372|uniprotkb:D3DKX7|ensemblfungi:YHR030C intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W psi-mi:slt2_yeast(display_long)|uniprotkb:YHR030C(locus name)|uniprotkb:SLT2(gene name)|psi-mi:SLT2(display_short)|uniprotkb:MPK1(gene name synonym) psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061509|imex:IM-25746-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011895.1|sgd:S000001072|ensemblfungi:YHR030C(gene)|ensemblfungi:YHR030C_mRNA(transcript)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043332"(mating projection tip)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0090364"(regulation of proteasome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-881907|dip:DIP-1448N|reactome:R-SCE-198765|reactome:R-SCE-4086398 refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 - crc64:559A3E0D3EBDE5F9 crc64:A1B7FD5B7076EC7F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/05/12 2017/05/12 rogid:1dJe7ldR8bi2mbvPugrkZAHrrVw559292 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rigid:pGAsRs5PxIsbas7liWLyE6P9Dwc false nub:n-n cub:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08018 uniprotkb:P40073 intact:EBI-12972|uniprotkb:D6VW57|ensemblfungi:YJL128C intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:pbs2_yeast(display_long)|uniprotkb:PBS2(gene name)|psi-mi:PBS2(display_short)|uniprotkb:HOG4(gene name synonym)|uniprotkb:SFS4(gene name synonym)|uniprotkb:SSK4(gene name synonym)|uniprotkb:YJL128C(locus name)|uniprotkb:J0699(orf name)|uniprotkb:Polymyxin B resistance protein 2(gene name synonym)|uniprotkb:Suppressor of fluoride sensitivity 4(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14061526|imex:IM-25746-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012407.2|sgd:S000003664|go:"GO:0031416"(NatB complex)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2VKN|reactome:R-SCE-168638|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450302|reactome:R-SCE-450321|reactome:R-SCE-6811555|go:"GO:0010494"(cytoplasmic stress granule)|ensemblfungi:YJL128C(gene)|ensemblfungi:YJL128C_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007231"(osmosensory signaling pathway)|mint:P08018|dip:DIP-2368N refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:9BC3435BDAFE8019 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:8kVv+9++58zg4knrpUYi+uGfLK8559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:Ggx8tZbYSAt8MzKGTpAbD3XBwzw false myc tag:?-? sufficient binding region:298-367(IPR001452)|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q05080 uniprotkb:P40073 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062215|imex:IM-25746-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:AE4A76C2F4043021 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:1cjXbr2jPvV+5KAHUgEDUWsNy/M false myc tag:?-? glutathione s tranferase tag:n-n|sufficient binding region:298-367(IPR001452) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q07533 uniprotkb:P40073 intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062226|imex:IM-25746-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:A1B7FD5B7076EC7F crc64:E467A4D50AA3EDB6 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:xNIicScWjaxzhFZD2aeUFnD1xmY false myc tag:?-? sufficient binding region:298-367(IPR001452)|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53901 uniprotkb:P40073 intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062237|imex:IM-25746-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - - crc64:E467A4D50AA3EDB6 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:EYW4YcsprPQNQS1+4LRuZdu07Zk false myc tag:?-? sufficient binding region:298-367(IPR001452)|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q07533 uniprotkb:P40073 intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062248|imex:IM-25746-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:A1B7FD5B7076EC7F crc64:E467A4D50AA3EDB6 figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:xNIicScWjaxzhFZD2aeUFnD1xmY false tag:?-?|sufficient binding region:160-210|necessary binding region:185-191 sufficient binding region:298-367(IPR001452)|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q05080 uniprotkb:P40073 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062264|imex:IM-25746-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:AE4A76C2F4043021 crc64:E467A4D50AA3EDB6 figure legend:Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:1cjXbr2jPvV+5KAHUgEDUWsNy/M false nub:n-n|ha tag:?-?|sufficient binding region:1-592 glutathione s tranferase tag:n-n|sufficient binding region:298-367(IPR001452) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q05080 uniprotkb:P40073 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062279|imex:IM-25746-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - crc64:AE4A76C2F4043021 crc64:E467A4D50AA3EDB6 figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:1cjXbr2jPvV+5KAHUgEDUWsNy/M false tag:?-?|sufficient binding region:269-349 glutathione s tranferase tag:n-n|sufficient binding region:298-367(IPR001452) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53901 uniprotkb:P40073 intact:EBI-28955|uniprotkb:D6W131|uniprotkb:Q6Q5J6|ensemblfungi:YNL152W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:inn1_yeast(display_long)|uniprotkb:N1765(orf name)|uniprotkb:YNL152W(locus name)|uniprotkb:INN1(gene name)|psi-mi:INN1(display_short) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062294|imex:IM-25746-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014247.1|sgd:S000005096|dip:DIP-4339N|mint:P53901|ensemblfungi:YNL152W(gene)|ensemblfungi:YNL152W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0044697"(HICS complex)|go:"GO:0051276"(chromosome organization)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR037791 refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - - crc64:E467A4D50AA3EDB6 figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:yAkoz0x4zwkY0XrwO61OpxIKZUM559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:EYW4YcsprPQNQS1+4LRuZdu07Zk false tag:?-?|sufficient binding region:351-409 sufficient binding region:298-367(IPR001452)|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P21339 uniprotkb:P40073 intact:EBI-11322|uniprotkb:D6W2P4|ensemblfungi:YOR188W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:msb1_yeast(display_long)|uniprotkb:MSB1(gene name)|psi-mi:MSB1(display_short)|uniprotkb:Multicopy suppressor of bud emergence 1(gene name synonym)|uniprotkb:YOR188W(locus name) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062307|imex:IM-25746-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR188W(gene)|ensemblfungi:YOR188W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030010"(establishment of cell polarity)|interpro:IPR012965(Protein of unknown function DUF1708)|interpro:IPR037508|refseq:NP_014831.3|sgd:S000005714|mint:P21339|dip:DIP-2687N refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 - - crc64:E467A4D50AA3EDB6 figure legend:Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:Lr2m/jqphbBj6HY6WgXvZzMFr+o559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rigid:d/r71echV35ledF3hFVYqHfcKY8 false tag:?-?|sufficient binding region:1-39 sufficient binding region:298-367(IPR001452)|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q07533 uniprotkb:Q05080 intact:EBI-31510|uniprotkb:D6VRN3|ensemblfungi:YDL117W intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:cyk3_yeast(display_long)|uniprotkb:CYK3(gene name)|psi-mi:CYK3(display_short)|uniprotkb:YDL117W(locus name) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Labedzka et al. (2012) pubmed:22623719|imex:IM-25746 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14062320|imex:IM-25746-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010166.1|sgd:S000002275|dip:DIP-6625N|mint:Q07533|ensemblfungi:YDL117W(gene)|ensemblfungi:YDL117W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0044697"(HICS complex)|go:"GO:1990344"(secondary cell septum biogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR036028|interpro:IPR038765 refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828 - crc64:A1B7FD5B7076EC7F crc64:AE4A76C2F4043021 figure legend:Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/05/12 2017/05/16 rogid:EDz4gFR7WaCPDMUXYwG4kUP1zzo559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rigid:mNvH3Tz4CiqcNW0P2zfWE7t/c5Y false tag:?-?|sufficient binding region:160-210 glutathione s tranferase tag:n-n|sufficient binding region:342-669 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)