#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14777	uniprotkb:Q9H211	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984705|imex:IM-25167-1|dip:DIP-200606E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rigid:+NqJF8UqVjK8NY3xLzMrAr1EI/0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H211	uniprotkb:Q9Y5N6	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	intact:EBI-374840|ensembl:ENSP00000219097|uniprotkb:B3KN89	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:orc6_human(display_long)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:ORC6L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984742|imex:IM-25167-3|dip:DIP-200607E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	ensembl:ENSG00000091651(gene)|ensembl:ENST00000219097(transcript)|go:"GO:0000808"(origin recognition complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0051782"(negative regulation of cell division)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|mint:Q9Y5N6|rcsb pdb:3M03|rcsb pdb:6KVG|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|refseq:NP_055136.1|dip:DIP-29692N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rogid:WElR6cWK58+oULzC4OgHBDVgikc9606	rigid:ypNOq36TP1ZE0iAdY8OvqqTklG0	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H211	uniprotkb:O14777	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984742|imex:IM-25167-3|dip:DIP-200607E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rigid:ypNOq36TP1ZE0iAdY8OvqqTklG0	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H211	uniprotkb:Q9BZD4	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984722|imex:IM-25167-2|dip:DIP-200605E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	rigid:mrqhLv1tb0tjbgoV4Xm0hGi/VwM	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H211	uniprotkb:O14777	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984722|imex:IM-25167-2|dip:DIP-200605E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rigid:mrqhLv1tb0tjbgoV4Xm0hGi/VwM	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75496	uniprotkb:Q9H211	intact:EBI-371669|uniprotkb:Q9H1Z1|uniprotkb:B3KMM8|ensembl:ENSP00000230056|ensembl:ENSP00000348902|ensembl:ENSP00000477506	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	psi-mi:gemi_human(display_long)|uniprotkb:GMNN(gene name)|psi-mi:GMNN(display_short)	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:"MI:0018"(two hybrid)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984820|imex:IM-25167-7|dip:DIP-60547E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056979.1|refseq:NP_001238918.1|refseq:NP_001238919.1|refseq:NP_001238920.1|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000104"(negative regulation of DNA-dependent DNA replication)|interpro:IPR022786|interpro:IPR029697|mint:O75496|rcsb pdb:1T6F|rcsb pdb:1UII|rcsb pdb:2LP0|rcsb pdb:2WVR|rcsb pdb:4BRY|reactome:R-HSA-68827|go:"GO:0009887"(animal organ morphogenesis)|reactome:R-HSA-68962|refseq:XP_005249216.1|ensembl:ENSG00000112312(gene)|ensembl:ENST00000230056(transcript)|ensembl:ENST00000356509(transcript)|ensembl:ENST00000620958(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|dip:DIP-31088N	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:4jWHqSy3+J1JqSU+kNTTYmeYjF49606	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rigid:YMcqVhUCFcF+j3zM0wujn6ZTDxo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14777	uniprotkb:Q9H211	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984803|imex:IM-25167-6|dip:DIP-200606E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rigid:+NqJF8UqVjK8NY3xLzMrAr1EI/0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14777	uniprotkb:Q9H211	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984781|imex:IM-25167-5|dip:DIP-200606E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rigid:+NqJF8UqVjK8NY3xLzMrAr1EI/0	false	green fluorescent protein tag:c-c|mutation disrupting interaction strength:420-460	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O14777	uniprotkb:Q9H211	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:"MI:0018"(two hybrid)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984762|imex:IM-25167-4|dip:DIP-200606E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rigid:+NqJF8UqVjK8NY3xLzMrAr1EI/0	false	sufficient binding region:306-642	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14777	uniprotkb:Q9H211	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short)	psi-mi:"MI:0018"(two hybrid)	Varma et al. (2012)	pubmed:22581055|doi:10.1038/ncb2489|imex:IM-25167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15984837|imex:IM-25167-8|dip:DIP-200606E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606	rigid:+NqJF8UqVjK8NY3xLzMrAr1EI/0	false	sufficient binding region:306-642	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)