#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A7F3 uniprotkb:P0A786 intact:EBI-906630|uniprotkb:P00478|uniprotkb:Q2M663|ensemblbacteria:AAC77201|ensemblbacteria:BAE78243 intact:EBI-906620|uniprotkb:P00479|uniprotkb:Q2M662|uniprotkb:Q47555|uniprotkb:Q47557|ensemblbacteria:AAC77202|ensemblbacteria:BAE78244 psi-mi:pyri_ecoli(display_long)|uniprotkb:pyrI(gene name)|psi-mi:pyrI(display_short)|uniprotkb:b4244(locus name)|uniprotkb:JW4203(locus name) psi-mi:pyrb_ecoli(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:b4245(locus name)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:JW4204(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Guo et al. (2012) pubmed:22547808|doi:10.1073/pnas.1119683109|imex:IM-20668 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15982648|imex:IM-20668-1|dip:DIP-63888E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418665.1|refseq:WP_000148581.1|dip:DIP-35088N|ensemblbacteria:AAC77201(transcript)|ensemblbacteria:b4244(gene)|ensemblbacteria:BAE78243(gene)|ensemblbacteria:BAE78243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009347"(aspartate carbamoyltransferase complex)|interpro:IPR002801(Aspartate transcarbamylase regulatory subunit)|interpro:IPR020542|interpro:IPR020545|interpro:IPR036792|interpro:IPR036793|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:6AT1|rcsb pdb:6KJ8|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC refseq:WP_000013046.1|refseq:NP_418666.1|dip:DIP-35089N|ensemblbacteria:AAC77202(transcript)|ensemblbacteria:b4245(gene)|ensemblbacteria:BAE78244(gene)|ensemblbacteria:BAE78244(transcript)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0070207"(protein homotrimerization)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR036901|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EKX|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3CSU|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:3NPM|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:5VMQ|rcsb pdb:6AT1|rcsb pdb:6KJ7|rcsb pdb:6KJ8|rcsb pdb:6KJ9|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:XbzGBbwrT2AMWUI3oI/hlUMiQEs83333 rogid:MOJ2J3sr2YNzPuAUnEZApcKduRs83333 rigid:rVVqw6KUZ7biC7iZnEzSlhN1Kyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A7F3 uniprotkb:P0A786 intact:EBI-906630|uniprotkb:P00478|uniprotkb:Q2M663|ensemblbacteria:AAC77201|ensemblbacteria:BAE78243 intact:EBI-906620|uniprotkb:P00479|uniprotkb:Q2M662|uniprotkb:Q47555|uniprotkb:Q47557|ensemblbacteria:AAC77202|ensemblbacteria:BAE78244 psi-mi:pyri_ecoli(display_long)|uniprotkb:pyrI(gene name)|psi-mi:pyrI(display_short)|uniprotkb:b4244(locus name)|uniprotkb:JW4203(locus name) psi-mi:pyrb_ecoli(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:b4245(locus name)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:JW4204(locus name) psi-mi:"MI:0227"(reverse phase chromatography) Guo et al. (2012) pubmed:22547808|doi:10.1073/pnas.1119683109|imex:IM-20668 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15982682|imex:IM-20668-3|dip:DIP-63888E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418665.1|refseq:WP_000148581.1|dip:DIP-35088N|ensemblbacteria:AAC77201(transcript)|ensemblbacteria:b4244(gene)|ensemblbacteria:BAE78243(gene)|ensemblbacteria:BAE78243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009347"(aspartate carbamoyltransferase complex)|interpro:IPR002801(Aspartate transcarbamylase regulatory subunit)|interpro:IPR020542|interpro:IPR020545|interpro:IPR036792|interpro:IPR036793|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:6AT1|rcsb pdb:6KJ8|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC refseq:WP_000013046.1|refseq:NP_418666.1|dip:DIP-35089N|ensemblbacteria:AAC77202(transcript)|ensemblbacteria:b4245(gene)|ensemblbacteria:BAE78244(gene)|ensemblbacteria:BAE78244(transcript)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0070207"(protein homotrimerization)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR036901|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EKX|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3CSU|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:3NPM|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:5VMQ|rcsb pdb:6AT1|rcsb pdb:6KJ7|rcsb pdb:6KJ8|rcsb pdb:6KJ9|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:XbzGBbwrT2AMWUI3oI/hlUMiQEs83333 rogid:MOJ2J3sr2YNzPuAUnEZApcKduRs83333 rigid:rVVqw6KUZ7biC7iZnEzSlhN1Kyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A7F3 uniprotkb:P0A786 intact:EBI-906630|uniprotkb:P00478|uniprotkb:Q2M663|ensemblbacteria:AAC77201|ensemblbacteria:BAE78243 intact:EBI-906620|uniprotkb:P00479|uniprotkb:Q2M662|uniprotkb:Q47555|uniprotkb:Q47557|ensemblbacteria:AAC77202|ensemblbacteria:BAE78244 psi-mi:pyri_ecoli(display_long)|uniprotkb:pyrI(gene name)|psi-mi:pyrI(display_short)|uniprotkb:b4244(locus name)|uniprotkb:JW4203(locus name) psi-mi:pyrb_ecoli(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:b4245(locus name)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:JW4204(locus name) psi-mi:"MI:0114"(x-ray crystallography) Guo et al. (2012) pubmed:22547808|doi:10.1073/pnas.1119683109|imex:IM-20668 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15982700|imex:IM-20668-4|dip:DIP-63888E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418665.1|refseq:WP_000148581.1|dip:DIP-35088N|ensemblbacteria:AAC77201(transcript)|ensemblbacteria:b4244(gene)|ensemblbacteria:BAE78243(gene)|ensemblbacteria:BAE78243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009347"(aspartate carbamoyltransferase complex)|interpro:IPR002801(Aspartate transcarbamylase regulatory subunit)|interpro:IPR020542|interpro:IPR020545|interpro:IPR036792|interpro:IPR036793|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:6AT1|rcsb pdb:6KJ8|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC refseq:WP_000013046.1|refseq:NP_418666.1|dip:DIP-35089N|ensemblbacteria:AAC77202(transcript)|ensemblbacteria:b4245(gene)|ensemblbacteria:BAE78244(gene)|ensemblbacteria:BAE78244(transcript)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0070207"(protein homotrimerization)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR036901|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EKX|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3CSU|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:3NPM|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:5VMQ|rcsb pdb:6AT1|rcsb pdb:6KJ7|rcsb pdb:6KJ8|rcsb pdb:6KJ9|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:XbzGBbwrT2AMWUI3oI/hlUMiQEs83333 rogid:MOJ2J3sr2YNzPuAUnEZApcKduRs83333 rigid:rVVqw6KUZ7biC7iZnEzSlhN1Kyg false - mutation:240-240,165-165 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A7F3 uniprotkb:P0A786 intact:EBI-906630|uniprotkb:P00478|uniprotkb:Q2M663|ensemblbacteria:AAC77201|ensemblbacteria:BAE78243 intact:EBI-906620|uniprotkb:P00479|uniprotkb:Q2M662|uniprotkb:Q47555|uniprotkb:Q47557|ensemblbacteria:AAC77202|ensemblbacteria:BAE78244 psi-mi:pyri_ecoli(display_long)|uniprotkb:pyrI(gene name)|psi-mi:pyrI(display_short)|uniprotkb:b4244(locus name)|uniprotkb:JW4203(locus name) psi-mi:pyrb_ecoli(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:b4245(locus name)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:JW4204(locus name) psi-mi:"MI:0826"(x ray scattering) Guo et al. (2012) pubmed:22547808|doi:10.1073/pnas.1119683109|imex:IM-20668 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15982665|imex:IM-20668-2|dip:DIP-63888E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418665.1|refseq:WP_000148581.1|dip:DIP-35088N|ensemblbacteria:AAC77201(transcript)|ensemblbacteria:b4244(gene)|ensemblbacteria:BAE78243(gene)|ensemblbacteria:BAE78243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009347"(aspartate carbamoyltransferase complex)|interpro:IPR002801(Aspartate transcarbamylase regulatory subunit)|interpro:IPR020542|interpro:IPR020545|interpro:IPR036792|interpro:IPR036793|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:6AT1|rcsb pdb:6KJ8|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC refseq:WP_000013046.1|refseq:NP_418666.1|dip:DIP-35089N|ensemblbacteria:AAC77202(transcript)|ensemblbacteria:b4245(gene)|ensemblbacteria:BAE78244(gene)|ensemblbacteria:BAE78244(transcript)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0070207"(protein homotrimerization)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR036901|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EKX|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3CSU|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:3NPM|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:5VMQ|rcsb pdb:6AT1|rcsb pdb:6KJ7|rcsb pdb:6KJ8|rcsb pdb:6KJ9|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:XbzGBbwrT2AMWUI3oI/hlUMiQEs83333 rogid:MOJ2J3sr2YNzPuAUnEZApcKduRs83333 rigid:rVVqw6KUZ7biC7iZnEzSlhN1Kyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A7F3 uniprotkb:P0A786 intact:EBI-906630|uniprotkb:P00478|uniprotkb:Q2M663|ensemblbacteria:AAC77201|ensemblbacteria:BAE78243 intact:EBI-906620|uniprotkb:P00479|uniprotkb:Q2M662|uniprotkb:Q47555|uniprotkb:Q47557|ensemblbacteria:AAC77202|ensemblbacteria:BAE78244 psi-mi:pyri_ecoli(display_long)|uniprotkb:pyrI(gene name)|psi-mi:pyrI(display_short)|uniprotkb:b4244(locus name)|uniprotkb:JW4203(locus name) psi-mi:pyrb_ecoli(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:b4245(locus name)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:JW4204(locus name) psi-mi:"MI:0071"(molecular sieving) Guo et al. (2012) pubmed:22547808|doi:10.1073/pnas.1119683109|imex:IM-20668 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15982721|imex:IM-20668-5|dip:DIP-63888E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418665.1|refseq:WP_000148581.1|dip:DIP-35088N|ensemblbacteria:AAC77201(transcript)|ensemblbacteria:b4244(gene)|ensemblbacteria:BAE78243(gene)|ensemblbacteria:BAE78243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009347"(aspartate carbamoyltransferase complex)|interpro:IPR002801(Aspartate transcarbamylase regulatory subunit)|interpro:IPR020542|interpro:IPR020545|interpro:IPR036792|interpro:IPR036793|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:6AT1|rcsb pdb:6KJ8|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC refseq:WP_000013046.1|refseq:NP_418666.1|dip:DIP-35089N|ensemblbacteria:AAC77202(transcript)|ensemblbacteria:b4245(gene)|ensemblbacteria:BAE78244(gene)|ensemblbacteria:BAE78244(transcript)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0070207"(protein homotrimerization)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR036901|rcsb pdb:1ACM|rcsb pdb:1AT1|rcsb pdb:1D09|rcsb pdb:1EKX|rcsb pdb:1EZZ|rcsb pdb:1F1B|rcsb pdb:1I5O|rcsb pdb:1NBE|rcsb pdb:1Q95|rcsb pdb:1R0B|rcsb pdb:1R0C|rcsb pdb:1RAA|rcsb pdb:1RAB|rcsb pdb:1RAC|rcsb pdb:1RAD|rcsb pdb:1RAE|rcsb pdb:1RAF|rcsb pdb:1RAG|rcsb pdb:1RAH|rcsb pdb:1RAI|rcsb pdb:1SKU|rcsb pdb:1TTH|rcsb pdb:1TU0|rcsb pdb:1TUG|rcsb pdb:1XJW|rcsb pdb:1ZA1|rcsb pdb:1ZA2|rcsb pdb:2A0F|rcsb pdb:2AIR|rcsb pdb:2AT1|rcsb pdb:2ATC|rcsb pdb:2FZC|rcsb pdb:2FZG|rcsb pdb:2FZK|rcsb pdb:2H3E|rcsb pdb:2HSE|rcsb pdb:2IPO|rcsb pdb:2QG9|rcsb pdb:2QGF|rcsb pdb:3AT1|rcsb pdb:3CSU|rcsb pdb:3D7S|rcsb pdb:3MPU|rcsb pdb:3NPM|rcsb pdb:4AT1|rcsb pdb:4E2F|rcsb pdb:4F04|rcsb pdb:4FYV|rcsb pdb:4FYW|rcsb pdb:4FYX|rcsb pdb:4FYY|rcsb pdb:5AT1|rcsb pdb:5VMQ|rcsb pdb:6AT1|rcsb pdb:6KJ7|rcsb pdb:6KJ8|rcsb pdb:6KJ9|rcsb pdb:6KJA|rcsb pdb:6KJB|rcsb pdb:7AT1|rcsb pdb:8AT1|rcsb pdb:8ATC|rcsb pdb:9ATC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:XbzGBbwrT2AMWUI3oI/hlUMiQEs83333 rogid:MOJ2J3sr2YNzPuAUnEZApcKduRs83333 rigid:rVVqw6KUZ7biC7iZnEzSlhN1Kyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)