#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NZZ3-1	uniprotkb:Q5VW32	intact:EBI-15979532|ensembl:ENSP00000223500	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:q9nzz3-1(display_long)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-114(orf name)|uniprotkb:PNAS-2(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979546|imex:IM-18012-1|dip:DIP-189605E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751303(isoform-parent)|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:d51qWkhjnFU1u0W1YkX0cEPI6b8	false	sufficient binding region:200-219	sufficient binding region:2-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NZZ3-1	uniprotkb:Q5VW32	intact:EBI-15979532|ensembl:ENSP00000223500	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:q9nzz3-1(display_long)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-114(orf name)|uniprotkb:PNAS-2(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979601|imex:IM-18012-3|dip:DIP-189605E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751303(isoform-parent)|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:d51qWkhjnFU1u0W1YkX0cEPI6b8	false	sufficient binding region:200-219|fluorescein-5-maleimide label:?-?	sufficient binding region:2-411|mutation disrupting interaction strength:212-212,208-208|mutation disrupting interaction strength:204-204|mutation disrupting interaction strength:348-348	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H444	uniprotkb:Q5VW32	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979635|imex:IM-18012-4|dip:DIP-189607E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:HVs+vnN68NSNzFCyHQVcoK1rM2s	false	sufficient binding region:121-224	sufficient binding region:2-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BY43	uniprotkb:Q5VW32	intact:EBI-747981|uniprotkb:Q32Q79|uniprotkb:Q86SZ8|uniprotkb:Q96QJ9|uniprotkb:Q9P026|uniprotkb:Q14D22|intact:EBI-11150912|ensembl:ENSP00000324205|ensembl:ENSP00000495982	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4a_human(display_long)|uniprotkb:Chromatin-modifying protein 4a(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-1(gene name synonym)|uniprotkb:SNF7-1(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix-2(gene name synonym)|uniprotkb:CHMP4A(gene name)|psi-mi:CHMP4A(display_short)|uniprotkb:C14orf123(gene name synonym)|uniprotkb:SHAX2(gene name synonym)|uniprotkb:CDA04(orf name)|uniprotkb:HSPC134(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979656|imex:IM-18012-5|dip:DIP-189606E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054888.2|ensembl:ENSG00000254505(gene)|ensembl:ENSG00000285302(gene)|ensembl:ENST00000347519(transcript)|ensembl:ENST00000645308(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008289"(lipid binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010324"(membrane invagination)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9BY43|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|rcsb pdb:3C3O|rcsb pdb:5MK1|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-39082N	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:37u80uKlCjnNuiXMSgos22rP0Ek9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:N7pwswLKqijZCX/MHLGmzH/npNQ	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NZZ3-1	uniprotkb:Q5VW32	intact:EBI-15979532|ensembl:ENSP00000223500	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:q9nzz3-1(display_long)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-114(orf name)|uniprotkb:PNAS-2(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979567|imex:IM-18012-2|dip:DIP-189605E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751303(isoform-parent)|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:d51qWkhjnFU1u0W1YkX0cEPI6b8	false	flag tag:?-?|necessary binding region:200-219|mutation disrupting interaction strength:213-213|mutation decreasing interaction strength:211-211|mutation decreasing interaction strength:214-214	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H444	uniprotkb:Q5VW32	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979677|imex:IM-18012-6|dip:DIP-189607E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:HVs+vnN68NSNzFCyHQVcoK1rM2s	false	flag tag:n-n|mutation decreasing interaction strength:217-217|mutation decreasing interaction strength:220-220	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H444	uniprotkb:Q5VW32	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979704|imex:IM-18012-7|dip:DIP-189607E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:HVs+vnN68NSNzFCyHQVcoK1rM2s	false	sufficient binding region:205-224|fluorescein-5-maleimide label:?-?	sufficient binding region:2-411|mutation disrupting interaction strength:212-212,208-208	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WUM4	uniprotkb:Q9H444	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979731|imex:IM-18012-8|dip:DIP-59418E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rigid:pJtWkFX8SoB/wZtQg5jK0WCXhcw	false	sufficient binding region:1-367	sufficient binding region:205-224|fluorescein-5-maleimide label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H444	uniprotkb:Q5VW32	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979754|imex:IM-18012-9|dip:DIP-189607E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:HVs+vnN68NSNzFCyHQVcoK1rM2s	false	flag tag:n-n	ha tag:n-n|mutation disrupting interaction strength:212-212,208-208	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NZZ3-1	uniprotkb:Q5VW32	intact:EBI-15979532|ensembl:ENSP00000223500	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:q9nzz3-1(display_long)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-114(orf name)|uniprotkb:PNAS-2(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979779|imex:IM-18012-10|dip:DIP-189605E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751303(isoform-parent)|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:d51qWkhjnFU1u0W1YkX0cEPI6b8	false	sufficient binding region:200-219|fluorescein-5-maleimide label:?-?|mutation disrupting interaction strength:211-211|mutation disrupting interaction strength:213-213|mutation disrupting interaction strength:214-214	sufficient binding region:2-411	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NZZ3-1	uniprotkb:Q5VW32	intact:EBI-15979532|ensembl:ENSP00000223500	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:q9nzz3-1(display_long)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-114(orf name)|uniprotkb:PNAS-2(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979811|imex:IM-18012-11|dip:DIP-189605E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751303(isoform-parent)|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:d51qWkhjnFU1u0W1YkX0cEPI6b8	false	flag tag:?-?	ha tag:n-n|mutation disrupting interaction strength:204-204|mutation disrupting interaction strength:348-348|mutation disrupting interaction strength:212-212,208-208	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H444	uniprotkb:Q5VW32	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979844|imex:IM-18012-12|dip:DIP-189607E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:HVs+vnN68NSNzFCyHQVcoK1rM2s	false	sufficient binding region:205-224|fluorescein-5-maleimide label:?-?|mutation decreasing interaction strength:217-217|mutation decreasing interaction strength:220-220	sufficient binding region:2-411	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NZZ3-1	uniprotkb:Q5VW32	intact:EBI-15979532|ensembl:ENSP00000223500	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:q9nzz3-1(display_long)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-114(orf name)|uniprotkb:PNAS-2(orf name)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979875|imex:IM-18012-13|dip:DIP-189605E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751303(isoform-parent)|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:d51qWkhjnFU1u0W1YkX0cEPI6b8	false	sufficient binding region:151-219	sufficient binding region:2-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CF2	uniprotkb:Q5VW32	intact:EBI-1221015|uniprotkb:B2RBZ1|ensembl:ENSP00000297265	intact:EBI-6286053|ensembl:ENSP00000343742|uniprotkb:Q96MG1|uniprotkb:B7Z9G5	psi-mi:chm4c_human(display_long)|uniprotkb:CHMP4C(gene name)|psi-mi:CHMP4C(display_short)|uniprotkb:SHAX3(gene name synonym)|uniprotkb:Chromatin-modifying protein 4c(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-3(gene name synonym)|uniprotkb:SNF7-3(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 3(gene name synonym)	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mu et al. (2012)	pubmed:22484091|doi:10.1016/j.str.2012.03.001|imex:IM-18012	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979896|imex:IM-18012-14|dip:DIP-189608E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689497.1|dip:DIP-38342N|ensembl:ENSG00000164695(gene)|ensembl:ENST00000297265(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009838"(abscission)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR005024(Snf7)|mint:Q96CF2|rcsb pdb:3C3R|rcsb pdb:5MK3|rcsb pdb:5V3R|rcsb pdb:5WA1|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676	refseq:XP_005273122.2|refseq:XP_011507516.1|ensembl:ENSG00000162819(gene)|ensembl:ENST00000340934(transcript)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM3|rcsb pdb:3ZXP|rcsb pdb:3UM2|dip:DIP-59406N|refseq:XP_016855863.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:LOB+DG//5OsYsyKDaziJYV2fxFo9606	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rigid:+/vaeHgcKum1J0105e6sru7A5fk	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)