#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q87ID2	uniprotkb:Q87ID1	intact:EBI-15979383|ensemblbacteria:BAC62017	intact:EBI-15802450|ensemblbacteria:BAC62018	psi-mi:q87id2_vibpa(display_long)|uniprotkb:VPA0674(locus name)	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Moore et al. (2012)	pubmed:22483119|doi:10.1016/j.str.2012.02.021|imex:IM-17604	taxid:223926(vibpa)|taxid:223926(vibpa)	taxid:223926(vibpa)|taxid:223926(vibpa)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979397|imex:IM-17604-1|dip:DIP-188906E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAC62017(gene)|ensemblbacteria:BAC62017(transcript)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR014301(TMAO reductase system periplasmic, TorT)|interpro:IPR028082|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|refseq:NP_800184.1|refseq:WP_005477549.1|dip:DIP-59648N	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	psi-mi:"MI:0465"(dip)	crc64:68DE77CD2FF93390	crc64:962F67DF6A44BC72	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bqr0xxdly37YfUf5I5YeGc05T+0223926	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rigid:snQ6/Msa3R+IKlAFnIHaO8zuIrU	false	sufficient binding region:29-329	sufficient binding region:51-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q87ID2	uniprotkb:Q87ID1	intact:EBI-15979383|ensemblbacteria:BAC62017	intact:EBI-15802450|ensemblbacteria:BAC62018	psi-mi:q87id2_vibpa(display_long)|uniprotkb:VPA0674(locus name)	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Moore et al. (2012)	pubmed:22483119|doi:10.1016/j.str.2012.02.021|imex:IM-17604	taxid:223926(vibpa)|taxid:223926(vibpa)	taxid:223926(vibpa)|taxid:223926(vibpa)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979439|imex:IM-17604-3|dip:DIP-188906E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAC62017(gene)|ensemblbacteria:BAC62017(transcript)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR014301(TMAO reductase system periplasmic, TorT)|interpro:IPR028082|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|refseq:NP_800184.1|refseq:WP_005477549.1|dip:DIP-59648N	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	psi-mi:"MI:0465"(dip)	crc64:68DE77CD2FF93390	crc64:962F67DF6A44BC72	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bqr0xxdly37YfUf5I5YeGc05T+0223926	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rigid:snQ6/Msa3R+IKlAFnIHaO8zuIrU	false	sufficient binding region:29-329	sufficient binding region:51-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q87ID1	uniprotkb:Q87ID1	intact:EBI-15802450|ensemblbacteria:BAC62018	intact:EBI-15802450|ensemblbacteria:BAC62018	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Moore et al. (2012)	pubmed:22483119|doi:10.1016/j.str.2012.02.021|imex:IM-17604	taxid:223926(vibpa)|taxid:223926(vibpa)	taxid:223926(vibpa)|taxid:223926(vibpa)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979460|imex:IM-17604-4|dip:DIP-102514E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	psi-mi:"MI:0465"(dip)	crc64:962F67DF6A44BC72	crc64:962F67DF6A44BC72	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rigid:kkGO+oD2LUY3xCR+h4E433vCFPo	false	sufficient binding region:51-323	sufficient binding region:51-323	-	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q87ID2	uniprotkb:Q87ID1	intact:EBI-15979383|ensemblbacteria:BAC62017	intact:EBI-15802450|ensemblbacteria:BAC62018	psi-mi:q87id2_vibpa(display_long)|uniprotkb:VPA0674(locus name)	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Moore et al. (2012)	pubmed:22483119|doi:10.1016/j.str.2012.02.021|imex:IM-17604	taxid:223926(vibpa)|taxid:223926(vibpa)	taxid:223926(vibpa)|taxid:223926(vibpa)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979478|imex:IM-17604-5|dip:DIP-188906E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAC62017(gene)|ensemblbacteria:BAC62017(transcript)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR014301(TMAO reductase system periplasmic, TorT)|interpro:IPR028082|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|refseq:NP_800184.1|refseq:WP_005477549.1|dip:DIP-59648N	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	psi-mi:"MI:0465"(dip)	crc64:68DE77CD2FF93390	crc64:962F67DF6A44BC72	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bqr0xxdly37YfUf5I5YeGc05T+0223926	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rigid:snQ6/Msa3R+IKlAFnIHaO8zuIrU	false	sufficient binding region:29-329	sufficient binding region:51-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q87ID2	uniprotkb:Q87ID1	intact:EBI-15979383|ensemblbacteria:BAC62017	intact:EBI-15802450|ensemblbacteria:BAC62018	psi-mi:q87id2_vibpa(display_long)|uniprotkb:VPA0674(locus name)	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:"MI:0071"(molecular sieving)	Moore et al. (2012)	pubmed:22483119|doi:10.1016/j.str.2012.02.021|imex:IM-17604	taxid:223926(vibpa)|taxid:223926(vibpa)	taxid:223926(vibpa)|taxid:223926(vibpa)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979418|imex:IM-17604-2|dip:DIP-188906E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAC62017(gene)|ensemblbacteria:BAC62017(transcript)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR014301(TMAO reductase system periplasmic, TorT)|interpro:IPR028082|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|refseq:NP_800184.1|refseq:WP_005477549.1|dip:DIP-59648N	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	psi-mi:"MI:0465"(dip)	crc64:68DE77CD2FF93390	crc64:962F67DF6A44BC72	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bqr0xxdly37YfUf5I5YeGc05T+0223926	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rigid:snQ6/Msa3R+IKlAFnIHaO8zuIrU	false	sufficient binding region:29-329	sufficient binding region:51-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q87ID2	uniprotkb:Q87ID1	intact:EBI-15979383|ensemblbacteria:BAC62017	intact:EBI-15802450|ensemblbacteria:BAC62018	psi-mi:q87id2_vibpa(display_long)|uniprotkb:VPA0674(locus name)	psi-mi:q87id1_vibpa(display_long)|uniprotkb:VPA0675(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Moore et al. (2012)	pubmed:22483119|doi:10.1016/j.str.2012.02.021|imex:IM-17604	taxid:223926(vibpa)|taxid:223926(vibpa)	taxid:223926(vibpa)|taxid:223926(vibpa)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15979499|imex:IM-17604-6|dip:DIP-188906E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAC62017(gene)|ensemblbacteria:BAC62017(transcript)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR014301(TMAO reductase system periplasmic, TorT)|interpro:IPR028082|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|refseq:NP_800184.1|refseq:WP_005477549.1|dip:DIP-59648N	ensemblbacteria:BAC62018(gene)|ensemblbacteria:BAC62018(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR011006(CheY-like)|interpro:IPR014302(Signal transduction histidine kinase, TMAO sensor TorS)|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037952|interpro:IPR038188|rcsb pdb:3I9Y|rcsb pdb:3O1H|rcsb pdb:3O1I|rcsb pdb:3O1J|dip:DIP-48299N|refseq:NP_800185.1|refseq:WP_005477577.1	psi-mi:"MI:0465"(dip)	crc64:68DE77CD2FF93390	crc64:962F67DF6A44BC72	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:bqr0xxdly37YfUf5I5YeGc05T+0223926	rogid:6NlX341oO/rCod8xklnVcr333cs223926	rigid:snQ6/Msa3R+IKlAFnIHaO8zuIrU	false	sufficient binding region:29-329|necessary binding region:309-329	sufficient binding region:51-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)