#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13619	uniprotkb:O94888	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976522|imex:IM-18096-1|dip:DIP-189832E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:+Kigs1OkJ4w+s2lSDwS3tmX0zco	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:Q13619	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976543|imex:IM-18096-2|dip:DIP-189822E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rigid:8OEv1vcFFcob+DJBxuZsMvYC+uA	false	sufficient binding region:1-407|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q13617	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976543|imex:IM-18096-2|dip:DIP-189822E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rigid:8OEv1vcFFcob+DJBxuZsMvYC+uA	false	sufficient binding region:1-407|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25694	uniprotkb:Q06682	intact:EBI-4308|ensemblfungi:YDL126C|uniprotkb:D6VRM4	intact:EBI-32041|uniprotkb:D6VSW2|ensemblfungi:YDR330W	psi-mi:cdc48_yeast(display_long)|uniprotkb:CDC48(gene name)|psi-mi:CDC48(display_short)|uniprotkb:Cell division cycle protein 48(gene name synonym)|uniprotkb:Transitional endoplasmic reticulum ATPase homolog(gene name synonym)|uniprotkb:YDL126C(locus name)	psi-mi:ubx5_yeast(display_long)|uniprotkb:UBX5(gene name)|psi-mi:UBX5(display_short)|uniprotkb:YDR330W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976589|imex:IM-18096-4|dip:DIP-64368E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010157.1|sgd:S000002284|ensemblfungi:YDL126C(gene)|ensemblfungi:YDL126C_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|dip:DIP-2704N|mint:P25694|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006274"(DNA replication termination)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016236"(macroautophagy)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030894"(replisome)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0036266"(Cdc48p-Npl4p-Vms1p AAA ATPase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043332"(mating projection tip)|go:"GO:0043624"|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990171"(SCF complex disassembly in response to cadmium stress)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6OAB|rcsb pdb:6OMB|rcsb pdb:6OPC|reactome:R-SCE-110320|reactome:R-SCE-3371511|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5689896|reactome:R-SCE-6798695|reactome:R-SCE-8876725	refseq:NP_010617.1|sgd:S000002738|dip:DIP-3938N|mint:Q06682|ensemblfungi:YDR330W(gene)|ensemblfungi:YDR330W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249	psi-mi:"MI:0465"(dip)	crc64:02ADDB9A227614D8	crc64:6B3DD79D98950523	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:qM/04kWcyjkQ3QCa3WklyvhNigE559292	rogid:98Q30TovI5iwvMy/idTjADlXjcw559292	rigid:PoaLZgYZKHeei+LHdH95J9+eVLQ	false	-	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976608|imex:IM-18096-5|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	ha tag:n-n|mutation disrupting interaction strength:689-689	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P55072	uniprotkb:Q9UNZ2	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	intact:EBI-721577|uniprotkb:Q7Z533|uniprotkb:Q9H102|uniprotkb:Q9NVL9|uniprotkb:Q9UI06|uniprotkb:Q5JXA5|uniprotkb:B2RD74|uniprotkb:Q5JXA4|uniprotkb:A2A2L1|ensembl:ENSP00000216879	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:nsf1c_human(display_long)|uniprotkb:p97 cofactor p47(gene name synonym)|uniprotkb:NSFL1C(gene name)|psi-mi:NSFL1C(display_short)|uniprotkb:UBXN2C(gene name synonym)|uniprotkb:UBX domain-containing protein 2C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976632|imex:IM-18096-6|dip:DIP-88995E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	refseq:NP_001193665.1|refseq:NP_057227.2|refseq:NP_061327.2|dip:DIP-39611N|refseq:XP_006723657.1|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0051117"(ATPase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1990730"(VCP-NSFL1C complex)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR012989(SEP)|interpro:IPR029071|interpro:IPR036241|mint:Q9UNZ2|rcsb pdb:1SS6|reactome:R-HSA-9013407|go:"GO:0000045"(autophagosome assembly)|ensembl:ENSG00000088833(gene)|ensembl:ENST00000216879(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rogid:LhK56TmbnfHvffJ2WUFlJJepje89606	rigid:dP9LmvNnklC/BCxmXmhVtxYDU2A	false	-	sufficient binding region:1-290|flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-4399559	uniprotkb:O94888	dip:DIP-24261N	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976565|imex:IM-18096-3|dip:DIP-189837E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:YlibCbkAapDUPrSvUIuwAXApQnQ	false	-	flag tag:n-n|necessary binding region:9-54|necessary binding region:408-489,9-54	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13617	uniprotkb:P55072	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976653|imex:IM-18096-7|dip:DIP-189827E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:3U9E5/A38EnXwEzrsHErvvQqSgA	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976653|imex:IM-18096-7|dip:DIP-189827E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:3U9E5/A38EnXwEzrsHErvvQqSgA	false	v5 tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	intact:EBI-4399559	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	dip:DIP-24261N	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976675|imex:IM-18096-8|dip:DIP-189841E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:gcroTysLuRtyV3DrfSts3xne3o4	false	flag tag:n-n|necessary binding region:9-54,408-489	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:P55072	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976675|imex:IM-18096-8|dip:DIP-189841E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:gcroTysLuRtyV3DrfSts3xne3o4	false	flag tag:n-n|necessary binding region:9-54,408-489	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15843	uniprotkb:O94888	intact:EBI-716247|uniprotkb:Q3SXN8|uniprotkb:Q6LES6|ensembl:ENSP00000250495|ensembl:ENSP00000496420	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:nedd8_human(display_long)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 8(gene name synonym)|uniprotkb:NEDD8(gene name)|psi-mi:NEDD8(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976698|imex:IM-18096-9|dip:DIP-189834E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006147.1|ensembl:ENSG00000129559(gene)|ensembl:ENSG00000285246(gene)|ensembl:ENST00000250495(transcript)|ensembl:ENST00000643069(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008104"(protein localization)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|mint:Q15843|rcsb pdb:1NDD|rcsb pdb:1R4M|rcsb pdb:1R4N|rcsb pdb:1XT9|rcsb pdb:2BKR|rcsb pdb:2KO3|rcsb pdb:2N7K|rcsb pdb:2NVU|rcsb pdb:3DBH|rcsb pdb:3DBL|rcsb pdb:3DBR|rcsb pdb:3DQV|rcsb pdb:3GZN|rcsb pdb:4F8C|rcsb pdb:4FBJ|rcsb pdb:4HCP|rcsb pdb:4P5O|rcsb pdb:6R7F|rcsb pdb:6R7I|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-2173789|reactome:R-HSA-5689603|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-917937|dip:DIP-29266N	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:qB1KNoIOwa1ONfphWDWjJri9hwE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:z1nU9oxZ7Nvsy0EltlYKGDABMGU	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P55072	uniprotkb:O94888	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976717|imex:IM-18096-10|dip:DIP-189823E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:8eOv0Y7DdR3tfr+bLv/nvMR1iYQ	false	-	flag tag:n-n|necessary binding region:408-489|necessary binding region:408-489,141-259	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:Q06682	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-32041|uniprotkb:D6VSW2|ensemblfungi:YDR330W	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:ubx5_yeast(display_long)|uniprotkb:UBX5(gene name)|psi-mi:UBX5(display_short)|uniprotkb:YDR330W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976741|imex:IM-18096-11|dip:DIP-189839E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_010617.1|sgd:S000002738|dip:DIP-3938N|mint:Q06682|ensemblfungi:YDR330W(gene)|ensemblfungi:YDR330W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249	psi-mi:"MI:0465"(dip)	crc64:22BC8B35034EDDEF	crc64:6B3DD79D98950523	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:98Q30TovI5iwvMy/idTjADlXjcw559292	rigid:CwgCdYYNeUYae9/2Lp13AXzbNFs	false	-	necessary binding region:359-376|mutation disrupting interaction strength:368-368|mutation disrupting interaction strength:368-368,365-365,361-361|flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q13618	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976770|imex:IM-18096-12|dip:DIP-189828E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:xI/8pHB9nckOW629STOqKba4KzQ9606	rigid:y5BRjFo+AtcVRPlglNqe3lNoI5I	false	flag tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:P55072	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976770|imex:IM-18096-12|dip:DIP-189828E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:y5BRjFo+AtcVRPlglNqe3lNoI5I	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13616	uniprotkb:O94888	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976792|imex:IM-18096-13|dip:DIP-189840E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:/IFTamwtIfIoD6eqXpm/hLzKGXY	false	-	flag tag:n-n|necessary binding region:284-301	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTX6	uniprotkb:P55072	intact:EBI-1551052|uniprotkb:Q9WUI7|ensembl:ENSMUSP00000031697	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:cul1_mouse(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976855|imex:IM-18096-16|dip:DIP-189824E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006506251.1|refseq:XP_006506252.1|refseq:NP_036172.1|refseq:XP_006506253.1|dip:DIP-39799N|ensembl:ENSMUSG00000029686(gene)|ensembl:ENSMUST00000031697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9WTX6|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	crc64:3E1F8B63C6E498F4	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:PvC7VcW1uCGZ/O7NUERQocqZdok10090	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:DGMjcQ7SKIJ2GunZZLcPK2F7cno	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13618	uniprotkb:O94888	intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976834|imex:IM-18096-15|dip:DIP-189829E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xI/8pHB9nckOW629STOqKba4KzQ9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:SNVlMJ9yWM1VfY+d4m3vL82oJmk	false	v5 tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13620	uniprotkb:O94888	intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976813|imex:IM-18096-14|dip:DIP-189833E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:iWOOKs4+70zS5t2qx4LJivTOoH8	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	intact:EBI-4399559	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	dip:DIP-24261N	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976874|imex:IM-18096-17|dip:DIP-189838E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:uvhHLuoP1mUMC4Or27180w1HUHM	false	flag tag:n-n|necessary binding region:408-489,284-301	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q13617	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976874|imex:IM-18096-17|dip:DIP-189838E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rigid:uvhHLuoP1mUMC4Or27180w1HUHM	false	flag tag:n-n|necessary binding region:408-489,284-301	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:P55072	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976874|imex:IM-18096-17|dip:DIP-189838E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:uvhHLuoP1mUMC4Or27180w1HUHM	false	flag tag:n-n|necessary binding region:408-489,284-301	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13616	uniprotkb:O94888	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976898|imex:IM-18096-18|dip:DIP-189840E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:/IFTamwtIfIoD6eqXpm/hLzKGXY	false	mutation disrupting interaction strength:681-681,678-679|necessary binding region:693-776	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-4399559	uniprotkb:O94888	dip:DIP-24261N	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976923|dip:DIP-189837E|imex:IM-18096-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	comment:Deletion of region 408-489 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:YlibCbkAapDUPrSvUIuwAXApQnQ	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13619	uniprotkb:P55072	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976943|imex:IM-18096-20|dip:DIP-189825E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:WaaYt5VedFhmL/1sv0GIFKirz+w	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:Q13619	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976962|imex:IM-18096-21|dip:DIP-189836E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rigid:2wKAmR64sMpHPXZI0Ej4NPnuGTI	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q13617	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976962|imex:IM-18096-21|dip:DIP-189836E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rigid:2wKAmR64sMpHPXZI0Ej4NPnuGTI	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q15843	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-716247|uniprotkb:Q3SXN8|uniprotkb:Q6LES6|ensembl:ENSP00000250495|ensembl:ENSP00000496420	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:nedd8_human(display_long)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 8(gene name synonym)|uniprotkb:NEDD8(gene name)|psi-mi:NEDD8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976962|imex:IM-18096-21|dip:DIP-189836E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_006147.1|ensembl:ENSG00000129559(gene)|ensembl:ENSG00000285246(gene)|ensembl:ENST00000250495(transcript)|ensembl:ENST00000643069(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008104"(protein localization)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|mint:Q15843|rcsb pdb:1NDD|rcsb pdb:1R4M|rcsb pdb:1R4N|rcsb pdb:1XT9|rcsb pdb:2BKR|rcsb pdb:2KO3|rcsb pdb:2N7K|rcsb pdb:2NVU|rcsb pdb:3DBH|rcsb pdb:3DBL|rcsb pdb:3DBR|rcsb pdb:3DQV|rcsb pdb:3GZN|rcsb pdb:4F8C|rcsb pdb:4FBJ|rcsb pdb:4HCP|rcsb pdb:4P5O|rcsb pdb:6R7F|rcsb pdb:6R7I|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-2173789|reactome:R-HSA-5689603|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-917937|dip:DIP-29266N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:qB1KNoIOwa1ONfphWDWjJri9hwE9606	rigid:2wKAmR64sMpHPXZI0Ej4NPnuGTI	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q13619	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976983|imex:IM-18096-22|dip:DIP-189830E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rigid:iIHcUlJmikfvArR1gvIHyfdua9I	false	flag tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:P55072	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15976983|imex:IM-18096-22|dip:DIP-189830E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:iIHcUlJmikfvArR1gvIHyfdua9I	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977005|imex:IM-18096-23|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	-	flag tag:n-n|sufficient binding region:1-407|necessary binding region:284-301|mutation disrupting interaction strength:293-293|mutation disrupting interaction strength:293-293,290-290,286-286	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q9WTX6	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-1551052|uniprotkb:Q9WUI7|ensembl:ENSMUSP00000031697	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul1_mouse(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977036|imex:IM-18096-24|dip:DIP-189826E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:XP_006506251.1|refseq:XP_006506252.1|refseq:NP_036172.1|refseq:XP_006506253.1|dip:DIP-39799N|ensembl:ENSMUSG00000029686(gene)|ensembl:ENSMUST00000031697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9WTX6|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168	psi-mi:"MI:0465"(dip)	-	crc64:3E1F8B63C6E498F4	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:PvC7VcW1uCGZ/O7NUERQocqZdok10090	rigid:OZuoT8WymSa2E4TIE2HEDb0buqE	false	flag tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:P55072	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977036|imex:IM-18096-24|dip:DIP-189826E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:OZuoT8WymSa2E4TIE2HEDb0buqE	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977058|imex:IM-18096-25|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	comment:Deletion of region 141-259 decreased the interaction rate/strength.|comment:Deletion of region 284-301 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTX6	uniprotkb:O94888	intact:EBI-1551052|uniprotkb:Q9WUI7|ensembl:ENSMUSP00000031697	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul1_mouse(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977101|imex:IM-18096-27|dip:DIP-189835E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006506251.1|refseq:XP_006506252.1|refseq:NP_036172.1|refseq:XP_006506253.1|dip:DIP-39799N|ensembl:ENSMUSG00000029686(gene)|ensembl:ENSMUST00000031697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9WTX6|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	crc64:3E1F8B63C6E498F4	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:PvC7VcW1uCGZ/O7NUERQocqZdok10090	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:2ew/Ki0AiIcAdnwV98g8yKbHLs4	false	ha tag:n-n|mutation decreasing interaction strength:720-720	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13619	uniprotkb:P55072	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977079|imex:IM-18096-26|dip:DIP-189830E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:iIHcUlJmikfvArR1gvIHyfdua9I	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13619	uniprotkb:O94888	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977079|imex:IM-18096-26|dip:DIP-189830E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:iIHcUlJmikfvArR1gvIHyfdua9I	false	v5 tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13619	uniprotkb:O94888	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977125|imex:IM-18096-28|dip:DIP-189832E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	comment:Deletion of region 141-259 decreased the interaction rate/strength.|comment:Deletion of region 141-259 and 284-301 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:+Kigs1OkJ4w+s2lSDwS3tmX0zco	false	-	flag tag:n-n|necessary binding region:284-301|necessary binding region:408-489,284-301	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977151|imex:IM-18096-29|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	sufficient binding region:380-745	flag tag:n-n|necessary binding region:284-301|necessary binding region:408-489,284-301	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTX6	uniprotkb:P55072	intact:EBI-1551052|uniprotkb:Q9WUI7|ensembl:ENSMUSP00000031697	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:cul1_mouse(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977177|imex:IM-18096-30|dip:DIP-189826E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006506251.1|refseq:XP_006506252.1|refseq:NP_036172.1|refseq:XP_006506253.1|dip:DIP-39799N|ensembl:ENSMUSG00000029686(gene)|ensembl:ENSMUST00000031697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9WTX6|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	crc64:3E1F8B63C6E498F4	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:PvC7VcW1uCGZ/O7NUERQocqZdok10090	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:OZuoT8WymSa2E4TIE2HEDb0buqE	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WTX6	uniprotkb:O94888	intact:EBI-1551052|uniprotkb:Q9WUI7|ensembl:ENSMUSP00000031697	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul1_mouse(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977177|imex:IM-18096-30|dip:DIP-189826E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006506251.1|refseq:XP_006506252.1|refseq:NP_036172.1|refseq:XP_006506253.1|dip:DIP-39799N|ensembl:ENSMUSG00000029686(gene)|ensembl:ENSMUST00000031697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9WTX6|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	crc64:3E1F8B63C6E498F4	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:PvC7VcW1uCGZ/O7NUERQocqZdok10090	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:OZuoT8WymSa2E4TIE2HEDb0buqE	false	v5 tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:Q13617	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977220|imex:IM-18096-32|dip:DIP-189827E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rigid:3U9E5/A38EnXwEzrsHErvvQqSgA	false	flag tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	uniprotkb:P55072	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977220|imex:IM-18096-32|dip:DIP-189827E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:3U9E5/A38EnXwEzrsHErvvQqSgA	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94888	intact:EBI-4399559	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	dip:DIP-24261N	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977199|imex:IM-18096-31|dip:DIP-189842E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	comment:Deletion of region 141-259 and 408-489 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:5jKRMknuWGg+sDPYQoH/N6ctWPU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94888	uniprotkb:Q13617	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977199|imex:IM-18096-31|dip:DIP-189842E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	psi-mi:"MI:0465"(dip)	-	-	comment:Deletion of region 141-259 and 408-489 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rigid:5jKRMknuWGg+sDPYQoH/N6ctWPU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977242|imex:IM-18096-33|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	sufficient binding region:380-745	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977263|imex:IM-18096-34|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	-	flag tag:n-n|necessary binding region:284-301|necessary binding region:408-489,284-301|sufficient binding region:263-321	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13617	uniprotkb:O94888	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	intact:EBI-1993627|uniprotkb:D3DXB3|uniprotkb:Q6ZP77|uniprotkb:Q86X20|uniprotkb:Q8N327|ensembl:ENSP00000296328	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:ubxn7_human(display_long)|uniprotkb:UBXD7(gene name synonym)|uniprotkb:UBXN7(gene name)|psi-mi:UBXN7(display_short)|uniprotkb:KIAA0794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	den et al. (2012)	pubmed:22466964|doi:10.1038/nsmb.2269|imex:IM-18096	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15977289|imex:IM-18096-35|dip:DIP-189831E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	refseq:NP_056377.1|dip:DIP-47029N|ensembl:ENSG00000163960(gene)|ensembl:ENST00000296328(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR017346(Uncharacterised conserved protein UCP037991, UAS, UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:1WJ4|rcsb pdb:2DAL|rcsb pdb:2DLX|rcsb pdb:5X3P|rcsb pdb:5X4L|reactome:R-HSA-8951664	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	rogid:TyFBtC4hXtG1WTSl8wLgPIoDxpg9606	rigid:gk++GS+N3JeZMSilLRNgR0P5D0k	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)