#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O25896 uniprotkb:O25896 intact:EBI-528005|ensemblbacteria:AAD08380 intact:EBI-528005|ensemblbacteria:AAD08380 psi-mi:nikr_helpy(display_long)|uniprotkb:HP_1338(locus name) psi-mi:nikr_helpy(display_long)|uniprotkb:HP_1338(locus name) psi-mi:"MI:0826"(x ray scattering) West et al. (2012) pubmed:22451934|doi:"https://doi.org/10.1073/pnas.1120283109"|imex:IM-20654 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15976266|imex:IM-20654-1|dip:DIP-5483E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_208130.1|dip:DIP-3711N|ensemblbacteria:AAD08380(transcript)|ensemblbacteria:HP_1338(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010045"(response to nickel cation)|go:"GO:0016151"(nickel cation binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR002145(CopG-like DNA-binding)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR014864(NikR C terminal nickel binding)|interpro:IPR022988|interpro:IPR027271|rcsb pdb:2CA9|rcsb pdb:2CAD|rcsb pdb:2CAJ|rcsb pdb:2WVB|rcsb pdb:2WVC|rcsb pdb:2WVD|rcsb pdb:2WVE|rcsb pdb:2WVF|rcsb pdb:3LGH|rcsb pdb:3PHT|rcsb pdb:3QSI|rcsb pdb:6MRJ|refseq:WP_000380787.1|mint:O25896 refseq:NP_208130.1|dip:DIP-3711N|ensemblbacteria:AAD08380(transcript)|ensemblbacteria:HP_1338(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010045"(response to nickel cation)|go:"GO:0016151"(nickel cation binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR002145(CopG-like DNA-binding)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR014864(NikR C terminal nickel binding)|interpro:IPR022988|interpro:IPR027271|rcsb pdb:2CA9|rcsb pdb:2CAD|rcsb pdb:2CAJ|rcsb pdb:2WVB|rcsb pdb:2WVC|rcsb pdb:2WVD|rcsb pdb:2WVE|rcsb pdb:2WVF|rcsb pdb:3LGH|rcsb pdb:3PHT|rcsb pdb:3QSI|rcsb pdb:6MRJ|refseq:WP_000380787.1|mint:O25896 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:4JMQbfefVdYdWX1rI0BOQ6bcQx085962 rogid:4JMQbfefVdYdWX1rI0BOQ6bcQx085962 rigid:XXNdROTUm0qurWA6f3mNkLYVzpY false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O25896 uniprotkb:O25896 intact:EBI-528005|ensemblbacteria:AAD08380 intact:EBI-528005|ensemblbacteria:AAD08380 psi-mi:nikr_helpy(display_long)|uniprotkb:HP_1338(locus name) psi-mi:nikr_helpy(display_long)|uniprotkb:HP_1338(locus name) psi-mi:"MI:0114"(x-ray crystallography) West et al. (2012) pubmed:22451934|doi:"https://doi.org/10.1073/pnas.1120283109"|imex:IM-20654 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15976284|imex:IM-20654-2|dip:DIP-5483E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_208130.1|dip:DIP-3711N|ensemblbacteria:AAD08380(transcript)|ensemblbacteria:HP_1338(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010045"(response to nickel cation)|go:"GO:0016151"(nickel cation binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR002145(CopG-like DNA-binding)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR014864(NikR C terminal nickel binding)|interpro:IPR022988|interpro:IPR027271|rcsb pdb:2CA9|rcsb pdb:2CAD|rcsb pdb:2CAJ|rcsb pdb:2WVB|rcsb pdb:2WVC|rcsb pdb:2WVD|rcsb pdb:2WVE|rcsb pdb:2WVF|rcsb pdb:3LGH|rcsb pdb:3PHT|rcsb pdb:3QSI|rcsb pdb:6MRJ|refseq:WP_000380787.1|mint:O25896 refseq:NP_208130.1|dip:DIP-3711N|ensemblbacteria:AAD08380(transcript)|ensemblbacteria:HP_1338(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010045"(response to nickel cation)|go:"GO:0016151"(nickel cation binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR002145(CopG-like DNA-binding)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR014864(NikR C terminal nickel binding)|interpro:IPR022988|interpro:IPR027271|rcsb pdb:2CA9|rcsb pdb:2CAD|rcsb pdb:2CAJ|rcsb pdb:2WVB|rcsb pdb:2WVC|rcsb pdb:2WVD|rcsb pdb:2WVE|rcsb pdb:2WVF|rcsb pdb:3LGH|rcsb pdb:3PHT|rcsb pdb:3QSI|rcsb pdb:6MRJ|refseq:WP_000380787.1|mint:O25896 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:4JMQbfefVdYdWX1rI0BOQ6bcQx085962 rogid:4JMQbfefVdYdWX1rI0BOQ6bcQx085962 rigid:XXNdROTUm0qurWA6f3mNkLYVzpY false sufficient binding region:58-148 sufficient binding region:58-148 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)