#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61466	uniprotkb:P70323	intact:EBI-371529|uniprotkb:P70384|uniprotkb:Q8R0I7|ensembl:ENSMUSP00000023759	intact:EBI-13635846|uniprotkb:Q60706|uniprotkb:Q99MP0|uniprotkb:Q99P22	psi-mi:smrd1_mouse(display_long)|uniprotkb:Smarcd1(gene name)|psi-mi:Smarcd1(display_short)|uniprotkb:Baf60a(gene name synonym)|uniprotkb:D15Kz1(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym)|uniprotkb:Protein D15KZ1(gene name synonym)	psi-mi:tbx1_mouse(display_long)|uniprotkb:Testis-specific T-box protein(gene name synonym)|uniprotkb:Tbx1(gene name)|psi-mi:Tbx1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (2011)	pubmed:22438823|imex:IM-25641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638846|imex:IM-25641-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000023018(gene)|ensembl:ENSMUST00000023759(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q61466|rcsb pdb:1UHR|reactome:R-MMU-3214858|reactome:R-MMU-8939243|refseq:NP_114030.2|dip:DIP-33019N	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0035176"(social behavior)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043587"(tongue morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071600"(otic vesicle morphogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097152"(mesenchymal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000027"(regulation of animal organ morphogenesis)|go:"GO:2001037"(positive regulation of tongue muscle cell differentiation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|refseq:NP_035662.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|interpro:IPR036960	-	-	-	figure legend:9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo)	-	2017/01/27	2017/01/27	rogid:Jn7+Fss6GbjcN8ys8cI5T5fw1qE10090	rogid:FkgWdsOHg7gy3yQU2oJqxrKTP2A10090	rigid:NvRrTnW/nhjXAGR9zIN6YpGk+0c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61466	uniprotkb:P70323	intact:EBI-371529|uniprotkb:P70384|uniprotkb:Q8R0I7|ensembl:ENSMUSP00000023759	intact:EBI-13635846|uniprotkb:Q60706|uniprotkb:Q99MP0|uniprotkb:Q99P22	psi-mi:smrd1_mouse(display_long)|uniprotkb:Smarcd1(gene name)|psi-mi:Smarcd1(display_short)|uniprotkb:Baf60a(gene name synonym)|uniprotkb:D15Kz1(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym)|uniprotkb:Protein D15KZ1(gene name synonym)	psi-mi:tbx1_mouse(display_long)|uniprotkb:Testis-specific T-box protein(gene name synonym)|uniprotkb:Tbx1(gene name)|psi-mi:Tbx1(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Chen et al. (2011)	pubmed:22438823|imex:IM-25641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638857|imex:IM-25641-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000023018(gene)|ensembl:ENSMUST00000023759(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q61466|rcsb pdb:1UHR|reactome:R-MMU-3214858|reactome:R-MMU-8939243|refseq:NP_114030.2|dip:DIP-33019N	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0035176"(social behavior)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043587"(tongue morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071600"(otic vesicle morphogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097152"(mesenchymal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000027"(regulation of animal organ morphogenesis)|go:"GO:2001037"(positive regulation of tongue muscle cell differentiation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|refseq:NP_035662.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|interpro:IPR036960	go:"GO:0005634"(nucleus)	-	-	figure legend:8A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-p19)|taxid:10090(Mus musculus embryonic teratocarcinoma cell line,  epithelial-like, induced by retinoic acid)	-	2017/01/27	2017/01/27	rogid:Jn7+Fss6GbjcN8ys8cI5T5fw1qE10090	rogid:FkgWdsOHg7gy3yQU2oJqxrKTP2A10090	rigid:NvRrTnW/nhjXAGR9zIN6YpGk+0c	false	-	protein a tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70323	uniprotkb:Q8VHL1	intact:EBI-13635846|uniprotkb:Q60706|uniprotkb:Q99MP0|uniprotkb:Q99P22	intact:EBI-8323066|uniprotkb:Q8C7Y6|intact:MINT-4114741|uniprotkb:Q80UU3|uniprotkb:Q6ZPJ6|ensembl:ENSMUSP00000043492	psi-mi:tbx1_mouse(display_long)|uniprotkb:Testis-specific T-box protein(gene name synonym)|uniprotkb:Tbx1(gene name)|psi-mi:Tbx1(display_short)	psi-mi:setd7_mouse(display_long)|uniprotkb:Setd7(gene name)|psi-mi:Setd7(display_short)|uniprotkb:Set7(gene name synonym)|uniprotkb:Kiaa1717(gene name synonym)|uniprotkb:Set9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (2011)	pubmed:22438823|imex:IM-25641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638873|imex:IM-25641-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0035176"(social behavior)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043587"(tongue morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071600"(otic vesicle morphogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097152"(mesenchymal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000027"(regulation of animal organ morphogenesis)|go:"GO:2001037"(positive regulation of tongue muscle cell differentiation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|refseq:NP_035662.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|interpro:IPR036960	refseq:NP_542983.3|ensembl:ENSMUSG00000037111(gene)|ensembl:ENSMUST00000037141(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8VHL1|reactome:R-MMU-3214841	go:"GO:0005634"(nucleus)	-	function:Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro|comment:mint	figure legend:8B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-p19cl6)|taxid:10090(mouse-P19Cl6--P19 subline which  differentiates into beating cardiomyocytes)	-	2017/01/27	2017/01/27	rogid:FkgWdsOHg7gy3yQU2oJqxrKTP2A10090	rogid:FKZi8IXkvQ3tyBbGXJdBvVbfvb410090	rigid:ekq7FiGf0NVxucBcVJd5JrXbkPY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70323	uniprotkb:Q61466	intact:EBI-13635846|uniprotkb:Q60706|uniprotkb:Q99MP0|uniprotkb:Q99P22	intact:EBI-371529|uniprotkb:P70384|uniprotkb:Q8R0I7|ensembl:ENSMUSP00000023759	psi-mi:tbx1_mouse(display_long)|uniprotkb:Testis-specific T-box protein(gene name synonym)|uniprotkb:Tbx1(gene name)|psi-mi:Tbx1(display_short)	psi-mi:smrd1_mouse(display_long)|uniprotkb:Smarcd1(gene name)|psi-mi:Smarcd1(display_short)|uniprotkb:Baf60a(gene name synonym)|uniprotkb:D15Kz1(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym)|uniprotkb:Protein D15KZ1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (2011)	pubmed:22438823|imex:IM-25641	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638873|imex:IM-25641-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0035176"(social behavior)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043587"(tongue morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071600"(otic vesicle morphogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097152"(mesenchymal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000027"(regulation of animal organ morphogenesis)|go:"GO:2001037"(positive regulation of tongue muscle cell differentiation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|refseq:NP_035662.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|interpro:IPR036960	ensembl:ENSMUSG00000023018(gene)|ensembl:ENSMUST00000023759(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q61466|rcsb pdb:1UHR|reactome:R-MMU-3214858|reactome:R-MMU-8939243|refseq:NP_114030.2|dip:DIP-33019N	go:"GO:0005634"(nucleus)	-	-	figure legend:8B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-p19cl6)|taxid:10090(mouse-P19Cl6--P19 subline which  differentiates into beating cardiomyocytes)	-	2017/01/27	2017/01/27	rogid:FkgWdsOHg7gy3yQU2oJqxrKTP2A10090	rogid:Jn7+Fss6GbjcN8ys8cI5T5fw1qE10090	rigid:ekq7FiGf0NVxucBcVJd5JrXbkPY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)