#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P78972 uniprotkb:O59767 intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:"MI:0096"(pull down) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15975490|imex:IM-17652-1|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ psi-mi:"MI:0465"(dip) crc64:52E021FD4EECE5DE crc64:EEC3EA6D3790C4BF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false sufficient binding region:87-488|strep ii tag:n-n sufficient binding region:1-223 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78972 uniprotkb:O14417 intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:"MI:0096"(pull down) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15975490|imex:IM-17652-1|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 psi-mi:"MI:0465"(dip) crc64:52E021FD4EECE5DE crc64:DC9D1D213450C925 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false sufficient binding region:87-488|strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14417 uniprotkb:O59767 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:"MI:0114"(x-ray crystallography) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15975534|imex:IM-17652-3|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ psi-mi:"MI:0465"(dip) crc64:DC9D1D213450C925 crc64:EEC3EA6D3790C4BF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false - sufficient binding region:1-223 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14417 uniprotkb:P78972 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0114"(x-ray crystallography) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15975534|imex:IM-17652-3|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 psi-mi:"MI:0465"(dip) crc64:DC9D1D213450C925 crc64:52E021FD4EECE5DE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false - sufficient binding region:87-488 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14417 uniprotkb:O59767 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:"MI:0071"(molecular sieving) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15975556|imex:IM-17652-4|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ psi-mi:"MI:0465"(dip) crc64:DC9D1D213450C925 crc64:EEC3EA6D3790C4BF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false - sufficient binding region:1-223 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O14417 uniprotkb:P78972 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0071"(molecular sieving) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15975556|imex:IM-17652-4|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 psi-mi:"MI:0465"(dip) crc64:DC9D1D213450C925 crc64:52E021FD4EECE5DE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false - sufficient binding region:87-488 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P78972 uniprotkb:O14417 intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:"MI:0071"(molecular sieving) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15975514|imex:IM-17652-2|dip:DIP-66060E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 psi-mi:"MI:0465"(dip) crc64:52E021FD4EECE5DE crc64:DC9D1D213450C925 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rigid:cRr6dtV/2+SWjn6J56fRj19tFMc false sufficient binding region:87-488 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O14417 uniprotkb:O59767 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:"MI:0226"(ion exchange chromatography) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15975578|imex:IM-17652-5|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ psi-mi:"MI:0465"(dip) crc64:DC9D1D213450C925 crc64:EEC3EA6D3790C4BF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false - sufficient binding region:1-223 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14417 uniprotkb:P78972 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0226"(ion exchange chromatography) Chao et al. (2012) pubmed:22437499|doi:"https://doi.org/10.1038/nature10896"|imex:IM-17652 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15975578|imex:IM-17652-5|dip:DIP-67504E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 psi-mi:"MI:0465"(dip) crc64:DC9D1D213450C925 crc64:52E021FD4EECE5DE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false - sufficient binding region:87-488 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)