#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8K3Y6 uniprotkb:Q8K3Y6 intact:EBI-8860250 intact:EBI-8860250 psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Chen et al. (2012) pubmed:22407013|doi:10.1038/nsmb.2243|imex:IM-18093 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15974228|imex:IM-18093-1|dip:DIP-189818E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rigid:2zcEbveLe1qqwDrVID4D2vmVkn0 false sufficient binding region:1-225 sufficient binding region:1-225 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95453 uniprotkb:Q8K3Y6 intact:EBI-372832|uniprotkb:B2RCB3|ensembl:ENSP00000387911|ensembl:ENSP00000478668|intact:EBI-28988750|uniprotkb:B4DSB0|uniprotkb:B4DDG8|uniprotkb:B4DWR4|uniprotkb:B4E1H6 intact:EBI-8860250 psi-mi:parn_human(display_long)|uniprotkb:PARN(gene name)|psi-mi:PARN(display_short)|uniprotkb:Polyadenylate-specific ribonuclease(gene name synonym)|uniprotkb:Deadenylating nuclease(gene name synonym)|uniprotkb:Deadenylation nuclease(gene name synonym)|uniprotkb:DAN(gene name synonym) psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2012) pubmed:22407013|doi:10.1038/nsmb.2243|imex:IM-18093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15974246|imex:IM-18093-2|dip:DIP-189819E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002573.1|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:0110008"(ncRNA deadenylation)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014789("Poly(A)-specific ribonuclease, RNA binding")|interpro:IPR034042|interpro:IPR035979|interpro:IPR036397|interpro:IPR036867|mint:O95453|rcsb pdb:2A1R|rcsb pdb:2A1S|rcsb pdb:3CTR|reactome:R-HSA-380994|reactome:R-HSA-429947|reactome:R-HSA-450604|ensembl:ENSG00000140694(gene)|ensembl:ENSG00000274829(gene)|ensembl:ENST00000437198(transcript)|ensembl:ENST00000615183(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007292"(female gamete generation)|go:"GO:0009451"(RNA modification)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043169"(cation binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|refseq:NP_001127949.1|refseq:NP_001229921.1|ensembl:ENST00000341484|ensembl:ENSP00000345456|ensembl:ENST00000420015|ensembl:ENSP00000410525|ensembl:ENSP00000387911|ensembl:ENST00000539279|ensembl:ENSP00000444381|ensembl:ENSP00000478668|ensembl:ENST00000618929|ensembl:ENSP00000484279|ensembl:ENST00000631868|ensembl:ENSP00000488554|ensembl:ENST00000634004|ensembl:ENSP00000487634|dip:DIP-31124N rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:V/6onCtb7dz2cK4pEHQwvHqEFuQ9606 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rigid:eeYoY+f5BV7VkHDss9+1V3oPdDQ false - sufficient binding region:1-254|myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8K3Y6 uniprotkb:Q8K3Y6 intact:EBI-8860250 intact:EBI-8860250 psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chen et al. (2012) pubmed:22407013|doi:10.1038/nsmb.2243|imex:IM-18093 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15974306|imex:IM-18093-5|dip:DIP-189818E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rigid:V2OTcW78PtdXaj499N1t9jYu3gQ false sufficient binding region:1-254|necessary binding region:1-10|myc tag:c-c|mutation decreasing interaction strength:133-133 sufficient binding region:1-254|necessary binding region:1-10|flag tag:c-c|mutation decreasing interaction strength:133-133 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8K3Y6 uniprotkb:Q9NQT4 intact:EBI-8860250 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2012) pubmed:22407013|doi:10.1038/nsmb.2243|imex:IM-18093 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15974285|imex:IM-18093-4|dip:DIP-59333E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rigid:60TcjagzkuADG31/MJdCxRC+ukQ false sufficient binding region:1-254|myc tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8K3Y6 uniprotkb:Q8K3Y6 intact:EBI-8860250 intact:EBI-8860250 psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Chen et al. (2012) pubmed:22407013|doi:10.1038/nsmb.2243|imex:IM-18093 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15974267|imex:IM-18093-3|dip:DIP-189818E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rigid:2zcEbveLe1qqwDrVID4D2vmVkn0 false sufficient binding region:1-225 sufficient binding region:1-225 - 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92841 uniprotkb:Q8K3Y6 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 intact:EBI-8860250 psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:zcchv_rat(display_long)|uniprotkb:Zc3hav1(gene name)|psi-mi:Zc3hav1(display_short)|uniprotkb:Zap(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2012) pubmed:22407013|doi:10.1038/nsmb.2243|imex:IM-18093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15974341|imex:IM-18093-6|dip:DIP-59326E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N rgd:628694|dip:DIP-29842N|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|rcsb pdb:3U9G psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 rogid:1v/UHcQ3JSTi4YGD1l3f7258qGs10116 rigid:d52NDBfhQQVUUnlQaBeTwgV4Yuo false - sufficient binding region:1-254|myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)