#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O25916 uniprotkb:O25916 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Stelter et al. (2012) pubmed:22405014|doi:10.1016/j.str.2012.01.020|imex:IM-17595 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15974147|imex:IM-17595-1|dip:DIP-188894E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N psi-mi:"MI:0465"(dip) comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rigid:3TsfsBIe9Qc7x/LMbhWxGyWWOWQ false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O25916 uniprotkb:O25916 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:"MI:0071"(molecular sieving) Stelter et al. (2012) pubmed:22405014|doi:10.1016/j.str.2012.01.020|imex:IM-17595 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15974182|imex:IM-17595-3|dip:DIP-188894E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N psi-mi:"MI:0465"(dip) comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rigid:3TsfsBIe9Qc7x/LMbhWxGyWWOWQ false sufficient binding region:152-488 sufficient binding region:152-488 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O25916 uniprotkb:O25916 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:"MI:0114"(x-ray crystallography) Stelter et al. (2012) pubmed:22405014|doi:10.1016/j.str.2012.01.020|imex:IM-17595 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15974164|imex:IM-17595-2|dip:DIP-188894E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N psi-mi:"MI:0465"(dip) comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rigid:3TsfsBIe9Qc7x/LMbhWxGyWWOWQ false sufficient binding region:152-488 sufficient binding region:152-488 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O25916 uniprotkb:O25916 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 intact:EBI-7529552|intact:MINT-181617|ensemblbacteria:AAD08402 psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:dnab_helpy(display_long)|uniprotkb:HP_1362(locus name)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short) psi-mi:"MI:0067"(light scattering) Stelter et al. (2012) pubmed:22405014|doi:10.1016/j.str.2012.01.020|imex:IM-17595 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15974200|imex:IM-17595-4|dip:DIP-188894E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N mint:O25916|refseq:WP_000349722.1|refseq:NP_208154.1|ensemblbacteria:AAD08402(transcript)|ensemblbacteria:HP_1362(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:3GXV|rcsb pdb:4A1F|rcsb pdb:4ZC0|dip:DIP-3388N psi-mi:"MI:0465"(dip) comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins comment:mint|function:Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rogid:mE+3jUtRVjT3fQ16TTLYqZnc67A85962 rigid:3TsfsBIe9Qc7x/LMbhWxGyWWOWQ false sufficient binding region:152-488 sufficient binding region:152-488 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)