#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8MSQ4 uniprotkb:P48609 intact:EBI-870203|ensemblmetazoa:FBpp0083099 intact:EBI-94216|intact:EBI-1627775|uniprotkb:Q94878|uniprotkb:Q9V7D8|ensemblmetazoa:FBpp0086483 psi-mi:q8msq4_drome(display_long)|uniprotkb:dMEKK1(gene name synonym)|uniprotkb:Dmel\CG7717(gene name synonym)|uniprotkb:MEKK(gene name synonym)|uniprotkb:MEKK1(gene name synonym)|uniprotkb:MEKK4(gene name synonym)|uniprotkb:dMEKK(gene name synonym)|uniprotkb:D-MEKK1(gene name synonym)|uniprotkb:4(gene name synonym)|uniprotkb:D-Mekk1(gene name synonym)|uniprotkb:DmMEKK1(gene name synonym)|uniprotkb:dMEKK4(gene name synonym)|uniprotkb:Mekk1(gene name)|psi-mi:Mekk1(display_short)|uniprotkb:mekk1(gene name synonym)|uniprotkb:dMekk1(gene name synonym)|uniprotkb:mekk1a(gene name synonym)|uniprotkb:mekk1b(gene name synonym)|uniprotkb:Dmel_CG7717(orf name)|uniprotkb:CG7717(orf name) psi-mi:cdk5_drome(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:CG8203(orf name)|uniprotkb:Cell division protein kinase 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kang et al. (2012) pubmed:22388889|doi:10.1038/ncb2447|imex:IM-25165 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15973138|imex:IM-25165-1|dip:DIP-200603E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732373.1|flybase:FBgn0024329|dip:DIP-61848N|ensemblmetazoa:FBgn0024329(gene)|ensemblmetazoa:FBtr0083684(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031452"(negative regulation of heterochromatin assembly)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071475"(cellular hyperosmotic salinity response)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-5607761|reactome:R-DME-5668541|reactome:R-DME-5676590|go:"GO:0034605"(cellular response to heat) refseq:NP_477080.1|flybase:FBgn0013762|go:"GO:0106310"(protein serine kinase activity)|ensemblmetazoa:FBgn0013762(gene)|ensemblmetazoa:FBtr0087350(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007629"(flight behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051642"(centrosome localization)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-399956|reactome:R-DME-6804756|go:"GO:0106311"|dip:DIP-22131N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:jrb8uK835Q/cxOH0Znp+4prVZOQ7227 rogid:VNwgPo7AEv+BIJY9ncTvrZA2jQI7227 rigid:+dCVTjrmMvqnhSpYaNdZCgII1eM false flag tag:n-n ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)