#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61686	uniprotkb:Q8BUH8	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	intact:EBI-15972382|ensembl:ENSMUSP00000086779|uniprotkb:Q6P398|uniprotkb:Q80TA3	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:senp7_mouse(display_long)|uniprotkb:Senp7(gene name)|psi-mi:Senp7(display_short)|uniprotkb:Kiaa1707(gene name synonym)|uniprotkb:Susp2(gene name synonym)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972407|imex:IM-21950-1|dip:DIP-192581E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	ensembl:ENSMUSG00000052917(gene)|ensembl:ENSMUST00000089362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|refseq:NP_079759.2|refseq:XP_011244296.1|dip:DIP-60609N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rogid:RI02QEeCKvjIpE9NuhkABaKYDjk10090	rigid:gRRZ6t6FZdqVaV+a2PX9PKgqdDY	false	-	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P55854	uniprotkb:Q61686	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972426|imex:IM-21950-2|dip:DIP-192584E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rigid:6EnUFkkEbDVbpS7NRpNX3BhVTto	false	green fluorescent protein tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8BUH8	uniprotkb:Q61686	intact:EBI-15972382|ensembl:ENSMUSP00000086779|uniprotkb:Q6P398|uniprotkb:Q80TA3	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:senp7_mouse(display_long)|uniprotkb:Senp7(gene name)|psi-mi:Senp7(display_short)|uniprotkb:Kiaa1707(gene name synonym)|uniprotkb:Susp2(gene name synonym)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972489|imex:IM-21950-5|dip:DIP-192581E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000052917(gene)|ensembl:ENSMUST00000089362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|refseq:NP_079759.2|refseq:XP_011244296.1|dip:DIP-60609N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:RI02QEeCKvjIpE9NuhkABaKYDjk10090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rigid:gRRZ6t6FZdqVaV+a2PX9PKgqdDY	false	-	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BUH8	uniprotkb:P23198	intact:EBI-15972382|ensembl:ENSMUSP00000086779|uniprotkb:Q6P398|uniprotkb:Q80TA3	intact:EBI-78162|uniprotkb:Q921C4	psi-mi:senp7_mouse(display_long)|uniprotkb:Senp7(gene name)|psi-mi:Senp7(display_short)|uniprotkb:Kiaa1707(gene name synonym)|uniprotkb:Susp2(gene name synonym)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)	psi-mi:cbx3_mouse(display_long)|uniprotkb:Cbx3(gene name)|psi-mi:Cbx3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:M32(gene name synonym)	psi-mi:"MI:0096"(pull down)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972468|imex:IM-21950-4|dip:DIP-192582E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000052917(gene)|ensembl:ENSMUST00000089362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|refseq:NP_079759.2|refseq:XP_011244296.1|dip:DIP-60609N	go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|reactome:R-MMU-73772|reactome:R-MMU-8953750|dip:DIP-28136N|mint:P23198	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:RI02QEeCKvjIpE9NuhkABaKYDjk10090	rogid:mD/Ut3JqLl3k0Ut98GxlstErEGs10090	rigid:tH+/D0mVfhfqsYQRatvEcHLfMfQ	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BUH8	uniprotkb:P83917	intact:EBI-15972382|ensembl:ENSMUSP00000086779|uniprotkb:Q6P398|uniprotkb:Q80TA3	intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475	psi-mi:senp7_mouse(display_long)|uniprotkb:Senp7(gene name)|psi-mi:Senp7(display_short)|uniprotkb:Kiaa1707(gene name synonym)|uniprotkb:Susp2(gene name synonym)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)	psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972468|imex:IM-21950-4|dip:DIP-192582E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000052917(gene)|ensembl:ENSMUST00000089362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|refseq:NP_079759.2|refseq:XP_011244296.1|dip:DIP-60609N	ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:RI02QEeCKvjIpE9NuhkABaKYDjk10090	rogid:W2npW/vFRcuTkStKpknsAP69q6I10090	rigid:tH+/D0mVfhfqsYQRatvEcHLfMfQ	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BUH8	uniprotkb:Q61686	intact:EBI-15972382|ensembl:ENSMUSP00000086779|uniprotkb:Q6P398|uniprotkb:Q80TA3	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:senp7_mouse(display_long)|uniprotkb:Senp7(gene name)|psi-mi:Senp7(display_short)|uniprotkb:Kiaa1707(gene name synonym)|uniprotkb:Susp2(gene name synonym)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972468|imex:IM-21950-4|dip:DIP-192582E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000052917(gene)|ensembl:ENSMUST00000089362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|refseq:NP_079759.2|refseq:XP_011244296.1|dip:DIP-60609N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:RI02QEeCKvjIpE9NuhkABaKYDjk10090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rigid:tH+/D0mVfhfqsYQRatvEcHLfMfQ	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61686	uniprotkb:Q8BUH8	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	intact:EBI-15972382|ensembl:ENSMUSP00000086779|uniprotkb:Q6P398|uniprotkb:Q80TA3	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:senp7_mouse(display_long)|uniprotkb:Senp7(gene name)|psi-mi:Senp7(display_short)|uniprotkb:Kiaa1707(gene name synonym)|uniprotkb:Susp2(gene name synonym)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972447|imex:IM-21950-3|dip:DIP-192581E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	ensembl:ENSMUSG00000052917(gene)|ensembl:ENSMUST00000089362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|refseq:NP_079759.2|refseq:XP_011244296.1|dip:DIP-60609N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rogid:RI02QEeCKvjIpE9NuhkABaKYDjk10090	rigid:gRRZ6t6FZdqVaV+a2PX9PKgqdDY	false	glutathione s tranferase tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P63165	uniprotkb:Q61686	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maison et al. (2012)	pubmed:22388734|doi:10.1038/nsmb.2244|imex:IM-21950	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15972508|imex:IM-21950-6|dip:DIP-192583E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rigid:eb70rg7tOkzbPeMMNWEA9seR9Ts	false	green fluorescent protein tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)