#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9DAN1 uniprotkb:P52194 intact:EBI-15971896|ensembl:ENSMUSP00000033267 intact:EBI-7842592|ensembl:ENSMUSP00000002259|ensembl:ENSMUSP00000105457|uniprotkb:Q80YU3|uniprotkb:Q9D2K5|intact:MINT-4592857 psi-mi:pdilt_mouse(display_long)|uniprotkb:Pdilt(gene name)|psi-mi:Pdilt(display_short) psi-mi:clgn_mouse(display_long)|uniprotkb:Clgn(gene name)|psi-mi:Clgn(display_short)|uniprotkb:Meg1(gene name synonym)|uniprotkb:MEG 1 antigen(gene name synonym)|uniprotkb:Calnexin-T(gene name synonym)|uniprotkb:A2/6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tokuhiro et al. (2012) pubmed:22357757|doi:10.1073/pnas.1117963109|imex:IM-20643 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15971945|imex:IM-20643-1|dip:DIP-190248E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030968(gene)|ensembl:ENSMUST00000033267(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0016477"(cell migration)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:NP_082219.1|refseq:XP_006508276.2|refseq:XP_006508277.1|dip:DIP-60024N refseq:NP_001316556.1|ensembl:ENSMUSG00000002190(gene)|ensembl:ENSMUST00000002259(transcript)|ensembl:ENSMUST00000109831(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P52194|go:"GO:0007339"(binding of sperm to zona pellucida)|refseq:XP_011246600.1|refseq:NP_034034.2|dip:DIP-47581N psi-mi:"MI:0465"(dip) - comment:mint|function:Probably plays an important role in spermatogenesis. Binds calcium ions full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:gh1ZLiYQoA7Bgw/5+LIaFp8LQxk10090 rogid:INHsjdKHpsAtnWW5iUT/UX4pUfs10090 rigid:YA+434ATLi5gkSWmfzEX0bcIn+Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9DAN1 uniprotkb:Q9D9Q6 intact:EBI-15971896|ensembl:ENSMUSP00000033267 intact:EBI-15971920|ensembl:ENSMUSP00000019876|uniprotkb:G5E827 psi-mi:pdilt_mouse(display_long)|uniprotkb:Pdilt(gene name)|psi-mi:Pdilt(display_short) psi-mi:calr3_mouse(display_long)|uniprotkb:Calr3(gene name)|psi-mi:Calr3(display_short)|uniprotkb:Crt2(gene name synonym)|uniprotkb:Calreticulin-2(gene name synonym)|uniprotkb:Calsperin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tokuhiro et al. (2012) pubmed:22357757|doi:10.1073/pnas.1117963109|imex:IM-20643 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15971945|imex:IM-20643-1|dip:DIP-190248E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030968(gene)|ensembl:ENSMUST00000033267(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0016477"(cell migration)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:NP_082219.1|refseq:XP_006508276.2|refseq:XP_006508277.1|dip:DIP-60024N ensembl:ENSMUSG00000019732(gene)|ensembl:ENSMUST00000019876(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|refseq:NP_082776.2|dip:DIP-60025N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:gh1ZLiYQoA7Bgw/5+LIaFp8LQxk10090 rogid:dKwpoepeFoqt4/xCqCkpla72pQ410090 rigid:YA+434ATLi5gkSWmfzEX0bcIn+Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62287 uniprotkb:Q9DAN1 intact:EBI-15971963 intact:EBI-15971896|ensembl:ENSMUSP00000033267 psi-mi:q62287_mouse(display_long)|uniprotkb:Adam3(gene name)|psi-mi:Adam3(display_short)|uniprotkb:Cyrn(gene name synonym) psi-mi:pdilt_mouse(display_long)|uniprotkb:Pdilt(gene name)|psi-mi:Pdilt(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tokuhiro et al. (2012) pubmed:22357757|doi:10.1073/pnas.1117963109|imex:IM-20643 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15971986|imex:IM-20643-2|dip:DIP-190249E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR024079|interpro:IPR034027|refseq:NP_001311418.1|refseq:NP_033749.2|interpro:IPR036436 ensembl:ENSMUSG00000030968(gene)|ensembl:ENSMUST00000033267(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0016477"(cell migration)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:NP_082219.1|refseq:XP_006508276.2|refseq:XP_006508277.1|dip:DIP-60024N psi-mi:"MI:0465"(dip) crc64:8AAE0DE6C5757C4C - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:akbk82cBYMVa9zdU8w6stc4LYBc10090 rogid:gh1ZLiYQoA7Bgw/5+LIaFp8LQxk10090 rigid:GzTzqjaUCwyOSk9zHjQm5qqaoVs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62287 uniprotkb:Q9DAN1 intact:EBI-15971963 intact:EBI-15971896|ensembl:ENSMUSP00000033267 psi-mi:q62287_mouse(display_long)|uniprotkb:Adam3(gene name)|psi-mi:Adam3(display_short)|uniprotkb:Cyrn(gene name synonym) psi-mi:pdilt_mouse(display_long)|uniprotkb:Pdilt(gene name)|psi-mi:Pdilt(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tokuhiro et al. (2012) pubmed:22357757|doi:10.1073/pnas.1117963109|imex:IM-20643 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15972003|imex:IM-20643-3|dip:DIP-190249E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR024079|interpro:IPR034027|refseq:NP_001311418.1|refseq:NP_033749.2|interpro:IPR036436 ensembl:ENSMUSG00000030968(gene)|ensembl:ENSMUST00000033267(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0016477"(cell migration)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:NP_082219.1|refseq:XP_006508276.2|refseq:XP_006508277.1|dip:DIP-60024N psi-mi:"MI:0465"(dip) crc64:8AAE0DE6C5757C4C - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:akbk82cBYMVa9zdU8w6stc4LYBc10090 rogid:gh1ZLiYQoA7Bgw/5+LIaFp8LQxk10090 rigid:GzTzqjaUCwyOSk9zHjQm5qqaoVs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9D9Q6 uniprotkb:Q62287 intact:EBI-15971920|ensembl:ENSMUSP00000019876|uniprotkb:G5E827 intact:EBI-15971963 psi-mi:calr3_mouse(display_long)|uniprotkb:Calr3(gene name)|psi-mi:Calr3(display_short)|uniprotkb:Crt2(gene name synonym)|uniprotkb:Calreticulin-2(gene name synonym)|uniprotkb:Calsperin(gene name synonym) psi-mi:q62287_mouse(display_long)|uniprotkb:Adam3(gene name)|psi-mi:Adam3(display_short)|uniprotkb:Cyrn(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tokuhiro et al. (2012) pubmed:22357757|doi:10.1073/pnas.1117963109|imex:IM-20643 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15972020|imex:IM-20643-4|dip:DIP-190251E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019732(gene)|ensembl:ENSMUST00000019876(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|refseq:NP_082776.2|dip:DIP-60025N go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR024079|interpro:IPR034027|refseq:NP_001311418.1|refseq:NP_033749.2|interpro:IPR036436 psi-mi:"MI:0465"(dip) - crc64:8AAE0DE6C5757C4C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:dKwpoepeFoqt4/xCqCkpla72pQ410090 rogid:akbk82cBYMVa9zdU8w6stc4LYBc10090 rigid:wTSjXpI6u7JMN3mWpBJDqJBbBKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52194 uniprotkb:Q62287 intact:EBI-7842592|ensembl:ENSMUSP00000002259|ensembl:ENSMUSP00000105457|uniprotkb:Q80YU3|uniprotkb:Q9D2K5|intact:MINT-4592857 intact:EBI-15971963 psi-mi:clgn_mouse(display_long)|uniprotkb:Clgn(gene name)|psi-mi:Clgn(display_short)|uniprotkb:Meg1(gene name synonym)|uniprotkb:MEG 1 antigen(gene name synonym)|uniprotkb:Calnexin-T(gene name synonym)|uniprotkb:A2/6(gene name synonym) psi-mi:q62287_mouse(display_long)|uniprotkb:Adam3(gene name)|psi-mi:Adam3(display_short)|uniprotkb:Cyrn(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tokuhiro et al. (2012) pubmed:22357757|doi:10.1073/pnas.1117963109|imex:IM-20643 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15972037|imex:IM-20643-5|dip:DIP-190250E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001316556.1|ensembl:ENSMUSG00000002190(gene)|ensembl:ENSMUST00000002259(transcript)|ensembl:ENSMUST00000109831(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P52194|go:"GO:0007339"(binding of sperm to zona pellucida)|refseq:XP_011246600.1|refseq:NP_034034.2|dip:DIP-47581N go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR024079|interpro:IPR034027|refseq:NP_001311418.1|refseq:NP_033749.2|interpro:IPR036436 psi-mi:"MI:0465"(dip) comment:mint|function:Probably plays an important role in spermatogenesis. Binds calcium ions crc64:8AAE0DE6C5757C4C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:INHsjdKHpsAtnWW5iUT/UX4pUfs10090 rogid:akbk82cBYMVa9zdU8w6stc4LYBc10090 rigid:fZ3FURZVwa8LvgzjeRgYMnkwA/E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)