#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46674 uniprotkb:O94742 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:"MI:0114"(x-ray crystallography) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15970376|imex:IM-18090-1|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:B66B578ABB01E672 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46674 uniprotkb:Q08231 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15970376|imex:IM-18090-1|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:7026F1F6FCC73FFA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60896 uniprotkb:Q5JVF3-1 intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067 intact:EBI-15970419|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym) psi-mi:q5jvf3-1(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:HT004(orf name)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15970426|imex:IM-18090-3|dip:DIP-189803E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|intact:EBI-1051701(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:PWXTveLxuio5va1OslxM8lWAEK49606 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 rigid:bdeJnERscs99XZb6YV+9uyR2MDQ false - sufficient binding region:201-399 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O94742 uniprotkb:Q08231 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:"MI:0676"(tandem affinity purification) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970396|imex:IM-18090-2|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP psi-mi:"MI:0465"(dip) crc64:B66B578ABB01E672 crc64:7026F1F6FCC73FFA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false - tandem tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94742 uniprotkb:P46674 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970396|imex:IM-18090-2|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 psi-mi:"MI:0465"(dip) crc64:B66B578ABB01E672 crc64:0679DB1673DDACEB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false - sufficient binding region:250-563 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P46674 uniprotkb:O94742 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:"MI:0071"(molecular sieving) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15970523|imex:IM-18090-7|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:B66B578ABB01E672 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46674 uniprotkb:Q08231 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:"MI:0071"(molecular sieving) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15970523|imex:IM-18090-7|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:7026F1F6FCC73FFA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60896 uniprotkb:Q5JVF3-1 intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067 intact:EBI-15970419|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym) psi-mi:q5jvf3-1(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:HT004(orf name)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short) psi-mi:"MI:0071"(molecular sieving) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15970543|imex:IM-18090-8|dip:DIP-189803E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|intact:EBI-1051701(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:PWXTveLxuio5va1OslxM8lWAEK49606 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 rigid:bdeJnERscs99XZb6YV+9uyR2MDQ false - sufficient binding region:201-399 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08231 uniprotkb:P06704 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W intact:EBI-4259|uniprotkb:D6W2V8|ensemblfungi:YOR257W psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:cdc31_yeast(display_long)|uniprotkb:YOR257W(locus name)|uniprotkb:CDC31(gene name)|psi-mi:CDC31(display_short)|uniprotkb:DSK1(gene name synonym)|uniprotkb:Nucleoporin CDC31(gene name synonym)|uniprotkb:Nuclear pore protein CDC31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970562|imex:IM-18090-9|dip:DIP-80086E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP sgd:S000005783|refseq:NP_014900.3|dip:DIP-2273N|mint:P06704|ensemblfungi:YOR257W(gene)|ensemblfungi:YOR257W_mRNA(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:2DOQ|rcsb pdb:2GV5|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:4MBE psi-mi:"MI:0465"(dip) crc64:7026F1F6FCC73FFA crc64:25A546E76E1EF520 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rogid:86I08mPe40Ad0gBR5QUCymXTekc559292 rigid:/UQaJJKZVdW9jqyKrfN/C9RyXBw false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q08231 uniprotkb:Q6WNK7 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W intact:EBI-1251050|uniprotkb:D6VQB1|ensemblfungi:YBR111W-A psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:sus1_yeast(display_long)|uniprotkb:SUS1(gene name)|psi-mi:SUS1(display_short)|uniprotkb:YBR111W-A(locus name) psi-mi:"MI:0676"(tandem affinity purification) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970562|imex:IM-18090-9|dip:DIP-80086E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP refseq:NP_878049.2|sgd:S000028510|mint:Q6WNK7|dip:DIP-45499N|ensemblfungi:YBR111W-A_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000932"(P-body)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3KIK|rcsb pdb:3KJL|rcsb pdb:3M99|rcsb pdb:3MHH|rcsb pdb:4C31|rcsb pdb:4FIP|rcsb pdb:4FJC|rcsb pdb:4FK5|rcsb pdb:4MBE|rcsb pdb:4WA6|rcsb pdb:4ZUX|rcsb pdb:6AQR|rcsb pdb:6T9L|rcsb pdb:3MHS|ensemblfungi:YBR111W-A(gene) psi-mi:"MI:0465"(dip) crc64:7026F1F6FCC73FFA crc64:DB0DA0C9DC13FB21 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rogid:gR8l71iy7VBJ/AS7bXueosdEJqU559292 rigid:/UQaJJKZVdW9jqyKrfN/C9RyXBw false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q08231 uniprotkb:P46674 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970562|imex:IM-18090-9|dip:DIP-80086E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 psi-mi:"MI:0465"(dip) crc64:7026F1F6FCC73FFA crc64:0679DB1673DDACEB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rigid:/UQaJJKZVdW9jqyKrfN/C9RyXBw false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O60318 uniprotkb:P60896 intact:EBI-308480|uniprotkb:Q2M3C1|uniprotkb:Q9UMT4|ensembl:ENSP00000291688|ensembl:ENSP00000380820|uniprotkb:C9JL56|uniprotkb:Q6PJP6|uniprotkb:Q9BSY5 intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067 psi-mi:ganp_human(display_long)|uniprotkb:MCM3AP(gene name)|psi-mi:MCM3AP(display_short)|uniprotkb:GANP(gene name synonym)|uniprotkb:KIAA0572(gene name synonym)|uniprotkb:MAP80(gene name synonym)|uniprotkb:80 kDa MCM3-associated protein(gene name synonym)|uniprotkb:MCM3 acetylating protein(gene name synonym)|uniprotkb:MCM3 acetyltransferase(gene name synonym) psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970583|imex:IM-18090-10|dip:DIP-189805E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003897.2|ensembl:ENSG00000160294(gene)|ensembl:ENST00000291688(transcript)|ensembl:ENST00000397708(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0034728"(nucleosome organization)|go:"GO:0042393"(histone binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|interpro:IPR035979|rcsb pdb:4DHX|go:"GO:0003682"(chromatin binding)|refseq:XP_005261262.1|refseq:XP_005261260.1|refseq:XP_005261261.1|ensembl:ENSP00000291688|ensembl:ENSP00000380820|dip:DIP-31696N ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:7WgKNrY4EPZGmfDj7es5SWEfTYM9606 rogid:PWXTveLxuio5va1OslxM8lWAEK49606 rigid:9xAScZBft8hjvST2As9V3XkOzDE false glutathione s tranferase tag:n-n|sufficient binding region:686-981 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O60318 uniprotkb:Q5JVF3-1 intact:EBI-308480|uniprotkb:Q2M3C1|uniprotkb:Q9UMT4|ensembl:ENSP00000291688|ensembl:ENSP00000380820|uniprotkb:C9JL56|uniprotkb:Q6PJP6|uniprotkb:Q9BSY5 intact:EBI-15970419|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:ganp_human(display_long)|uniprotkb:MCM3AP(gene name)|psi-mi:MCM3AP(display_short)|uniprotkb:GANP(gene name synonym)|uniprotkb:KIAA0572(gene name synonym)|uniprotkb:MAP80(gene name synonym)|uniprotkb:80 kDa MCM3-associated protein(gene name synonym)|uniprotkb:MCM3 acetylating protein(gene name synonym)|uniprotkb:MCM3 acetyltransferase(gene name synonym) psi-mi:q5jvf3-1(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:HT004(orf name)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970583|imex:IM-18090-10|dip:DIP-189805E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003897.2|ensembl:ENSG00000160294(gene)|ensembl:ENST00000291688(transcript)|ensembl:ENST00000397708(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0015031"(protein transport)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0034728"(nucleosome organization)|go:"GO:0042393"(histone binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|interpro:IPR035979|rcsb pdb:4DHX|go:"GO:0003682"(chromatin binding)|refseq:XP_005261262.1|refseq:XP_005261260.1|refseq:XP_005261261.1|ensembl:ENSP00000291688|ensembl:ENSP00000380820|dip:DIP-31696N ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|intact:EBI-1051701(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:7WgKNrY4EPZGmfDj7es5SWEfTYM9606 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 rigid:9xAScZBft8hjvST2As9V3XkOzDE false glutathione s tranferase tag:n-n|sufficient binding region:686-981 sufficient binding region:201-399|his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46674 uniprotkb:O94742 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970495|imex:IM-18090-6|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:B66B578ABB01E672 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46674 uniprotkb:Q08231 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970495|imex:IM-18090-6|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:7026F1F6FCC73FFA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563|glutathione s tranferase tag:n-n his tag:n-n|mutation disrupting interaction strength:406-406,405-405 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P60896 uniprotkb:Q5JVF3-1 intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067 intact:EBI-15970419|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym) psi-mi:q5jvf3-1(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:HT004(orf name)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15970473|imex:IM-18090-5|dip:DIP-189803E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|intact:EBI-1051701(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:PWXTveLxuio5va1OslxM8lWAEK49606 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 rigid:bdeJnERscs99XZb6YV+9uyR2MDQ false - sufficient binding region:201-399|his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46674 uniprotkb:O94742 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970445|imex:IM-18090-4|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:B66B578ABB01E672 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:425-425,391-391 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46674 uniprotkb:Q08231 intact:EBI-16425|ensemblfungi:YDR159W|uniprotkb:D6VSD9 intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W psi-mi:sac3_yeast(display_long)|uniprotkb:SAC3(gene name)|psi-mi:SAC3(display_short)|uniprotkb:LEP1(gene name synonym)|uniprotkb:YDR159W(locus name)|uniprotkb:YD8358.13(orf name)|uniprotkb:Leucine permease transcriptional regulator(gene name synonym) psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15970445|imex:IM-18090-4|dip:DIP-189802E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR159W(gene)|ensemblfungi:YDR159W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030029"(actin filament-based process)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR017173(mRNA export factor Sac3)|interpro:IPR024293|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:3T5V|rcsb pdb:4C31|go:"GO:0000278"(mitotic cell cycle)|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:4MBE|sgd:S000002566|refseq:NP_010443.3|dip:DIP-2444N|mint:P46674 refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP psi-mi:"MI:0465"(dip) crc64:0679DB1673DDACEB crc64:7026F1F6FCC73FFA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+Mp7NTROr8M4th7GWIuIkh7VnU559292 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rigid:29XfbIV8KmaTAu2ErDtbiWHi2lE false sufficient binding region:250-563|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:425-425,391-391 his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O94742 uniprotkb:Q08231 intact:EBI-31337|uniprotkb:D6VSZ2|ensemblfungi:YDR363W-A intact:EBI-32097|uniprotkb:D6W1Z5|ensemblfungi:YOL072W psi-mi:sem1_yeast(display_long)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:DSH1(gene name synonym)|uniprotkb:YDR363W-A(locus name) psi-mi:thp1_yeast(display_long)|uniprotkb:Bud site selection protein 29(gene name synonym)|uniprotkb:THP1(gene name)|psi-mi:THP1(display_short)|uniprotkb:BUD29(gene name synonym)|uniprotkb:O1140(orf name)|uniprotkb:YOL072W(locus name) psi-mi:"MI:0096"(pull down) Ellisdon et al. (2012) pubmed:22343721|doi:10.1038/nsmb.2235|imex:IM-18090 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15970610|imex:IM-18090-11|dip:DIP-189804E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010651.3|sgd:S000007235|dip:DIP-8754N|mint:O94742|ensemblfungi:YDR363W-A(gene)|ensemblfungi:YDR363W-A_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030447"(filamentous growth)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0072742"(SAGA complex localization to transcription regulatory region)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3T5V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4TRQ|rcsb pdb:5A5B|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5UBP|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 refseq:NP_014569.1|sgd:S000005433|dip:DIP-5060N|mint:Q08231|ensemblfungi:YOL072W(gene)|ensemblfungi:YOL072W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040114|rcsb pdb:3T5V|rcsb pdb:4TRQ|rcsb pdb:5G5P|rcsb pdb:5L3T|rcsb pdb:5UBP psi-mi:"MI:0465"(dip) crc64:B66B578ABB01E672 crc64:7026F1F6FCC73FFA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:jW26dMSkSwiSL4WsgtoWcg98j9A559292 rogid:T3wxyg2KUFRn+NxQ+ZwRzRbEvXI559292 rigid:tSuBOU0utJN/T0zr6HYyoRiWeS4 false - his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)