#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9P270	uniprotkb:P23468	intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363416|imex:IM-25827-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:b9qbNdu9gsg9USu4+VdM1xFmvK4	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14965	uniprotkb:P23468	intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363437|imex:IM-25827-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:p8OTN0y6LKtpjx9rPzkj/XpCaEA	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96PY6	uniprotkb:P23468	intact:EBI-373615|uniprotkb:Q9Y594|ensembl:ENSP00000408020|uniprotkb:Q14CB7|uniprotkb:Q5H9T1|uniprotkb:Q6PIB8|uniprotkb:Q96SS2|uniprotkb:Q9H6P7|uniprotkb:Q05DG5|uniprotkb:G5E9Z3	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:nek1_human(display_long)|uniprotkb:NEK1(gene name)|psi-mi:NEK1(display_short)|uniprotkb:KIAA1901(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-55(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363443|imex:IM-25827-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186326.1|refseq:NP_001186327.1|refseq:NP_001186328.1|refseq:NP_001186329.1|refseq:NP_036356.1|ensembl:ENSG00000137601(gene)|ensembl:ENST00000439128(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4APC|rcsb pdb:4B9D|refseq:XP_011530305.1|refseq:XP_011530306.1	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:/Zes5a/DuVLXGUozIBoCHv4qtm89606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:9mupgTDEctJcX6O7mU6YhpRQzGw	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53350	uniprotkb:P23468	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363449|imex:IM-25827-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:024Zwhyi9jQlsOumaMk34nV5BpE	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29322	uniprotkb:P23468	intact:EBI-3905018|ensembl:ENSP00000166244|uniprotkb:Q9P269|uniprotkb:Q9NUA9|uniprotkb:Q6IN80|uniprotkb:Q8IUX6	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:epha8_human(display_long)|uniprotkb:EPHA8(gene name)|psi-mi:EPHA8(display_short)|uniprotkb:EEK(gene name synonym)|uniprotkb:KIAA1459(gene name synonym)|uniprotkb:EPH- and ELK-related kinase(gene name synonym)|uniprotkb:EPH-like kinase 3(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EEK(gene name synonym)|uniprotkb:HEK3(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363455|imex:IM-25827-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070886(gene)|ensembl:ENST00000166244(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016322"(neuron remodeling)|go:"GO:0019838"(growth factor binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR020691|interpro:IPR027936|interpro:IPR036116|rcsb pdb:1UCV|refseq:NP_065387.1|refseq:NP_001006944.1|rcsb pdb:1X5L|rcsb pdb:3KUL|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:T7sTgV46UYcGqs0KJIXmgVbePwI9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:30NG/aBDX1EcdXam8mrE7lbVRw4	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHD2	uniprotkb:P23468	intact:EBI-356402|intact:EBI-5773956|intact:EBI-1383470|uniprotkb:Q8IYV3|uniprotkb:Q9NUJ5|ensembl:ENSP00000329967|ensembl:ENSP00000498995|uniprotkb:A8K4S4	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:tbk1_human(display_long)|uniprotkb:TBK1(gene name)|psi-mi:TBK1(display_short)|uniprotkb:NAK(gene name synonym)|uniprotkb:TANK-binding kinase 1(gene name synonym)|uniprotkb:T2K(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363461|imex:IM-25827-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037386.1|go:"GO:0004672"(protein kinase activity)|ensembl:ENSG00000183735(gene)|ensembl:ENST00000331710(transcript)|ensembl:ENST00000650790(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901214"(regulation of neuron death)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR041087|interpro:IPR041309|mint:Q9UHD2|rcsb pdb:4EFO|rcsb pdb:4EUT|rcsb pdb:4EUU|rcsb pdb:4IM0|rcsb pdb:4IM2|rcsb pdb:4IM3|rcsb pdb:4IW0|rcsb pdb:4IWO|rcsb pdb:4IWP|rcsb pdb:4IWQ|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:5EP6|rcsb pdb:5W5V|rcsb pdb:6BNY|rcsb pdb:6BOD|rcsb pdb:6BOE|rcsb pdb:6CQ0|rcsb pdb:6CQ4|rcsb pdb:6CQ5|rcsb pdb:6NT9|rcsb pdb:6O8B|rcsb pdb:6RSR|rcsb pdb:6RST|rcsb pdb:6RSU|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3249367|reactome:R-HSA-3270619|reactome:R-HSA-9008059|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9679191|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|refseq:XP_005268866.1|refseq:XP_005268867.1|dip:DIP-27529N	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:Cf+RbPJBZTpm7XIqbAD2OEC6VEs9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:TBOPz2f5adyM5yjAx009mVdWR3g	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48730	uniprotkb:P23468	intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363467|imex:IM-25827-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:Rz5aON17Bfduv29izmgHa/FR1/49606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:GYBZWMtkoqRmO6pxwQe027lGPYc	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49674	uniprotkb:P23468	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363473|imex:IM-25827-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:jLFgV31hiD6lrnFXpaecLeEv0qA	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7KZI7	uniprotkb:P23468	intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363479|imex:IM-25827-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:nbnryqe1wPKXTRpE0rtWnfQBI3U	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96PF2	uniprotkb:P23468	intact:EBI-852089|uniprotkb:Q8IY55|ensembl:ENSP00000382544	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:tssk2_human(display_long)|uniprotkb:Serine/threonine-protein kinase 22B(gene name synonym)|uniprotkb:DiGeorge syndrome protein G(gene name synonym)|uniprotkb:TSSK2(gene name)|psi-mi:TSSK2(display_short)|uniprotkb:DGSG(gene name synonym)|uniprotkb:SPOGA2(gene name synonym)|uniprotkb:STK22B(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363485|imex:IM-25827-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443732.3|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007286"(spermatid development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005524"(ATP binding)|ensembl:ENSG00000206203(gene)|ensembl:ENST00000399635(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:Uz36gAlTmZRfyxDOURZUMXC16fs9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:u9dUDSd2kqD6N4tzScVDA3Wq0+8	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2TAL5	uniprotkb:P23468	intact:EBI-2854513|uniprotkb:Q6ZVK6|ensembl:ENSP00000373964	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:smtl2_human(display_long)|uniprotkb:SMTNL2(gene name)|psi-mi:SMTNL2(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363491|imex:IM-25827-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006721578.1|refseq:NP_001108446.1|refseq:NP_940903.2|ensembl:ENSG00000188176(gene)|ensembl:ENST00000389313(transcript)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0031941"(filamentous actin)|go:"GO:0045907"(positive regulation of vasoconstriction)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:RzYnqYlY2duXo4EA4BsXGc3FhwQ9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:bG1/ipdG37jfTVtJqDrHPXZRYCk	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQU5	uniprotkb:P23468	intact:EBI-1053685|ensembl:ENSP00000260404|ensembl:ENSP00000401153|ensembl:ENSP00000406873|ensembl:ENSP00000439597|ensembl:ENSP00000453858|ensembl:ENSP00000456785|uniprotkb:A8K2G2|uniprotkb:B3KYB0|uniprotkb:G5E9R2	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:pak6_human(display_long)|uniprotkb:p21-activated kinase 6(gene name synonym)|uniprotkb:PAK-5(gene name synonym)|uniprotkb:PAK6(gene name)|psi-mi:PAK6(display_short)|uniprotkb:PAK5(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363497|imex:IM-25827-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSG00000137843(gene)|ensembl:ENST00000260404(transcript)|ensembl:ENST00000441369(transcript)|ensembl:ENST00000453867(transcript)|ensembl:ENST00000542403(transcript)|ensembl:ENST00000558658(transcript)|ensembl:ENST00000560346(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001263646.1|refseq:NP_001122100.1|refseq:NP_001122101.1|refseq:NP_064553.1|refseq:NP_001263647.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0030054"(cell junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140058"(neuron projection arborization)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035066|interpro:IPR036936|rcsb pdb:2C30|rcsb pdb:2ODB|rcsb pdb:4KS7|rcsb pdb:4KS8|rcsb pdb:6QDR|rcsb pdb:6QDS|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013424	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:sLf1m1moEJrh+5QFw4V8UgWgxOQ9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:MW9thqjWMZmHIonQ8Bfw+cRM49g	false	-	binding-associated region:1201-1495	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51955	uniprotkb:P23468	intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363503|imex:IM-25827-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:7iozc82+IF+sGyerzvp571Uc1RM9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:FAli0hBlZVn8l9x9Y81SK6W0K4o	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HC98	uniprotkb:P23468	intact:EBI-740364|uniprotkb:Q96E83|uniprotkb:Q9ULX2|uniprotkb:B7Z2D9|uniprotkb:Q5TBG3|uniprotkb:Q5TBG9|uniprotkb:Q6FG86|uniprotkb:Q6IAR3|ensembl:ENSP00000319734|ensembl:ENSP00000362705|ensembl:ENSP00000441426|ensembl:ENSP00000442636	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:nek6_human(display_long)|uniprotkb:Never in mitosis A-related kinase 6(gene name synonym)|uniprotkb:Protein kinase SID6-1512(gene name synonym)|uniprotkb:NEK6(gene name)|psi-mi:NEK6(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363509|imex:IM-25827-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138473.1|refseq:NP_001159639.1|refseq:NP_001159640.1|refseq:NP_001159641.1|refseq:NP_001159642.1|refseq:NP_001159643.1|refseq:NP_055212.2|ensembl:ENSG00000119408(gene)|ensembl:ENST00000320246(transcript)|ensembl:ENST00000373603(transcript)|ensembl:ENST00000545174(transcript)|ensembl:ENST00000546191(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000922"(spindle pole)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|refseq:XP_005251721.1|refseq:XP_006716999.1|refseq:XP_016869706.1	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:khoXzC0KgPfn38NTbXQEgCldfsc9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:/kO5+1A2RVwF+L1L9+7DD1Rr7Q0	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14639	uniprotkb:P23468	intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363515|imex:IM-25827-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:UjnPGNR9RyuZHZSJBOqCZDTStRM	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WW87	uniprotkb:P23468	intact:EBI-16363521	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:q8ww87_human(display_long)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363524|imex:IM-25827-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:wgEK4ivxfPdRsVoQbnUEsaLBi7Y9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:2CHauMhf3+n9jkmBuQ44xZ3G88I	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51813	uniprotkb:P23468	intact:EBI-696657|uniprotkb:A6NIH9|uniprotkb:O60564|uniprotkb:Q12871|ensembl:ENSP00000308774|ensembl:ENSP00000340082|ensembl:ENSP00000350224	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:bmx_human(display_long)|uniprotkb:Bone marrow tyrosine kinase gene in chromosome X protein(gene name synonym)|uniprotkb:Epithelial and endothelial tyrosine kinase(gene name synonym)|uniprotkb:NTK38(gene name synonym)|uniprotkb:BMX(gene name)|psi-mi:BMX(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363530|imex:IM-25827-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001712.1|refseq:NP_975010.1|refseq:NP_001307795.1|ensembl:ENSG00000102010(gene)|ensembl:ENST00000342014(transcript)|ensembl:ENST00000348343(transcript)|ensembl:ENST00000357607(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007498"(mesoderm development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028840|interpro:IPR035875|interpro:IPR036860|rcsb pdb:2EKX|rcsb pdb:2YS2|rcsb pdb:3SXR|rcsb pdb:3SXS|rcsb pdb:6I99|reactome:R-HSA-111465|reactome:R-HSA-1660499	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:vEWqPrMe5xCQRPeNReXM+8Djcjg9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:pISiftaDOdzEFVXLZuXBDWmWIJo	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35568	uniprotkb:P23468	intact:EBI-517592|intact:EBI-28983786|ensembl:ENSP00000304895	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:irs1_human(display_long)|uniprotkb:IRS1(gene name)|psi-mi:IRS1(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363536|imex:IM-25827-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005535.1|ensembl:ENSP00000304895|dip:DIP-523N|ensembl:ENSG00000169047(gene)|ensembl:ENST00000305123(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:P35568|rcsb pdb:1IRS|rcsb pdb:1K3A|rcsb pdb:1QQG|rcsb pdb:2Z8C|rcsb pdb:5U1M|rcsb pdb:6BNT|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-112412|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-2219530|reactome:R-HSA-2428928|reactome:R-HSA-2586552|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-9603381|reactome:R-HSA-982772	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:n/9Epczwu5jOLSKCKhmIgR7CdOw9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:6NIH/Q4/cY6mNxUIJntdhS4Ap+E	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TDD1	uniprotkb:P23468	intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0089"(protein array)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363542|imex:IM-25827-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity)	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:T1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/07/28	2017/08/19	rogid:VzxEkRaOIND08jGJk3yyoztesjo9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:iHl8cQ16JUhSOYxroSKW1YmbwFE	false	-	binding-associated region:1201-1495|biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14965	uniprotkb:P23468	intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251	intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439	psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym)	psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Meehan et al. (2012)	pubmed:22305495|imex:IM-25827	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-16363431|imex:IM-25827-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U	refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932	-	-	-	figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-kelly)|taxid:9606(human KELLY-  Neuroblastoma cell line with ampification of N-MYC)	-	2017/07/28	2018/03/15	rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606	rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606	rigid:p8OTN0y6LKtpjx9rPzkj/XpCaEA	false	-	v5 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)