#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61830 uniprotkb:P40161 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-29119|uniprotkb:D6W0Y4|ensemblfungi:YNL206C psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:rt106_yeast(display_long)|uniprotkb:Regulator of Ty1 transposition protein 106(gene name synonym)|uniprotkb:YNL206C(locus name)|uniprotkb:N1346(orf name)|uniprotkb:RTT106(gene name)|psi-mi:RTT106(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zunder et al. (2012) pubmed:22198837|doi:10.1073/pnas.1119095109|imex:IM-20623 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15960984|imex:IM-20623-1|dip:DIP-150585E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_014193.1|sgd:S000005150|dip:DIP-4292N|mint:P40161|ensemblfungi:YNL206C(gene)|ensemblfungi:YNL206C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032196"(transposition)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR040770|interpro:IPR040993|rcsb pdb:2LH0|rcsb pdb:3FSS|rcsb pdb:3GYO|rcsb pdb:3GYP|rcsb pdb:3TO1|rcsb pdb:3TVV|rcsb pdb:3TW1 psi-mi:"MI:0465"(dip) crc64:A6115FEB480AC67A crc64:79CACA659A7F4F4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:A2isuuBEAm1qbw9kuBVV2var23M559292 rigid:IjxMBbtMf3WtTsLN/CHnmIs8GKA false - flag tag:c-c|mutation disrupting interaction strength:80-80|mutation disrupting interaction strength:86-86|mutation disrupting interaction strength:265-265 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04636 uniprotkb:P61830 intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zunder et al. (2012) pubmed:22198837|doi:10.1073/pnas.1119095109|imex:IM-20623 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15961012|imex:IM-20623-2|dip:DIP-146027E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G psi-mi:"MI:0465"(dip) crc64:02C04F620C7B1450 crc64:A6115FEB480AC67A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rigid:HWzbV/LI1MT4zeVTr+7nEYymVyI false myc tag:c-c|mutation disrupting interaction strength:252-252|mutation increasing interaction strength:308-308|mutation disrupting interaction strength:251-251|mutation disrupting interaction strength:249-249 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61830 uniprotkb:P40161 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-29119|uniprotkb:D6W0Y4|ensemblfungi:YNL206C psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:rt106_yeast(display_long)|uniprotkb:Regulator of Ty1 transposition protein 106(gene name synonym)|uniprotkb:YNL206C(locus name)|uniprotkb:N1346(orf name)|uniprotkb:RTT106(gene name)|psi-mi:RTT106(display_short) psi-mi:"MI:0096"(pull down) Zunder et al. (2012) pubmed:22198837|doi:10.1073/pnas.1119095109|imex:IM-20623 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15961043|imex:IM-20623-3|dip:DIP-150585E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_014193.1|sgd:S000005150|dip:DIP-4292N|mint:P40161|ensemblfungi:YNL206C(gene)|ensemblfungi:YNL206C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032196"(transposition)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR040770|interpro:IPR040993|rcsb pdb:2LH0|rcsb pdb:3FSS|rcsb pdb:3GYO|rcsb pdb:3GYP|rcsb pdb:3TO1|rcsb pdb:3TVV|rcsb pdb:3TW1 psi-mi:"MI:0465"(dip) crc64:A6115FEB480AC67A crc64:79CACA659A7F4F4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:A2isuuBEAm1qbw9kuBVV2var23M559292 rigid:IjxMBbtMf3WtTsLN/CHnmIs8GKA false - his tag:n-n|mutation disrupting interaction strength:80-80|mutation disrupting interaction strength:86-86|mutation disrupting interaction strength:265-265 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)