#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9WUI0	uniprotkb:P20293	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	intact:EBI-13637160|ensembl:ENSMUSP00000074236	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637252|imex:IM-25642-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	-	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WUI0	uniprotkb:Q9WUI0	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637287|imex:IM-25642-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	-	figure legend:S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:KEGyxU6M7yQhbU+6WGDGv/PnJCs	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02591	uniprotkb:Q9WUI0	intact:EBI-7457485|intact:MINT-4998459|ensembl:ENSMUSP00000021513	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:gsc_mouse(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637295|imex:IM-25642-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034481.1|ensembl:ENSMUSG00000021095(gene)|ensembl:ENSMUST00000021513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q02591	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	comment:mint|function:Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like activity when transplanted into Xenopus embryos	-	figure legend:S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:JP8dHDpRfNvyjVVZh5foSMbWxyg10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:FUZuFKWGCffyXVQ6WkfEwnOaouE	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WUI0	uniprotkb:P20293	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	intact:EBI-13637160|ensembl:ENSMUSP00000074236	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637278|imex:IM-25642-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	-	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20293	uniprotkb:Q9WUI0	intact:EBI-13637160|ensembl:ENSMUSP00000074236	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637310|imex:IM-25642-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	comment:mutant constructs val132ala, ile113arg and arg143ile interact with similar strength	figure legend:2B, 3A, 4D, S4A and B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	glutathione s tranferase tag:n-n|sufficient binding region:1-230|sufficient binding region:230-436	mutation decreasing interaction strength:126-126|ha tag:?-?|mutation with no effect:132-132|mutation with no effect:113-113|mutation with no effect:143-143	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70324	uniprotkb:Q9WUI0	intact:EBI-13637323|ensembl:ENSMUSP00000018748|uniprotkb:E9QM97|uniprotkb:Q60708|uniprotkb:Q8BWH7	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:tbx3_mouse(display_long)|uniprotkb:Tbx3(gene name)|psi-mi:Tbx3(display_short)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637318|imex:IM-25642-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018604(gene)|ensembl:ENSMUST00000018748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021761"(limbic system development)|go:"GO:0030539"(male genitalia development)|go:"GO:0030540"(female genitalia development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046884"(follicle-stimulating hormone secretion)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0032275"(luteinizing hormone secretion)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060596"(mammary placode formation)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072105"(ureteric peristalsis)|go:"GO:0090398"(cellular senescence)|go:"GO:1905072"(cardiac jelly development)|go:"GO:1905222"(atrioventricular canal morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000137"(negative regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR022582|interpro:IPR036960|refseq:NP_035665.2|refseq:XP_006530339.1	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	-	figure legend:S4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:szp3PNpy0hHRHc/hGmDAGnxouhA10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:78zMNyD18Vpmt0LaHoMwjdqm+l0	false	glutathione s tranferase tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70327	uniprotkb:Q9WUI0	intact:EBI-13637402|ensembl:ENSMUSP00000091579|uniprotkb:B2RU37|uniprotkb:Q5SDA2	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:tbx6_mouse(display_long)|uniprotkb:Tbx6(gene name)|psi-mi:Tbx6(display_short)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637397|imex:IM-25642-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000030699(gene)|ensembl:ENSMUST00000094037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|go:"GO:0007417"(central nervous system development)|refseq:NP_035668.2	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	-	figure legend:4D, S4A,|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:2MWaNwFdyyBgd4PjovfdXbsnEuY10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:umcyExyVEWQcsIu33E7KzQdd96Q	false	glutathione s tranferase tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ES03	uniprotkb:Q9WUI0	intact:EBI-13637441|ensembl:ENSMUSP00000052591|uniprotkb:Q9EPZ5|uniprotkb:Q9ESX1	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:tbx20_mouse(display_long)|uniprotkb:Tbx20(gene name)|psi-mi:Tbx20(display_short)|uniprotkb:Tbx12(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637436|imex:IM-25642-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031965(gene)|ensembl:ENSMUST00000052946(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0001947"(heart looping)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003171"(atrioventricular valve development)|go:"GO:0003175"(tricuspid valve development)|go:"GO:0003176"(aortic valve development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003193"(pulmonary valve formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035922"(foramen ovale closure)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0036306"(embryonic heart tube elongation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0006936"(muscle contraction)|go:"GO:0008015"(blood circulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0060577"(pulmonary vein morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|go:"GO:0010991"(negative regulation of SMAD protein complex assembly)|interpro:IPR036960|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0021524"(visceral motor neuron differentiation)|refseq:NP_001192014.1|refseq:NP_065242.1|refseq:NP_919239.1	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	-	figure legend:S4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:gNckcLHnu8noscsWEisB7n6R+FE10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:GQzreblO3xN0hrmZlcRnCNXt3fQ	false	glutathione s tranferase tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P20293	uniprotkb:Q9WUI0	intact:EBI-13637160|ensembl:ENSMUSP00000074236	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637759|imex:IM-25642-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	-	figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	ha tag:?-?	sufficient binding region:1-145|sufficient binding region:145-231|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WUI0	uniprotkb:Q9WUI0	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637870|imex:IM-25642-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	comment:mutant constructs val132ala, ile113arg and arg143ile interact with similar strength	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:KEGyxU6M7yQhbU+6WGDGv/PnJCs	false	glutathione s tranferase tag:n-n	ha tag:?-?|mutation decreasing interaction strength:126-126|mutation with no effect:132-132|mutation with no effect:113-113|mutation with no effect:143-143	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O54839	uniprotkb:Q9WUI0	intact:EBI-13637928|ensembl:ENSMUSP00000035020|uniprotkb:Q3UPL1|uniprotkb:Q52KJ1|uniprotkb:Q8BN22|uniprotkb:Q9JJL1|uniprotkb:Q9QYG7	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:eomes_mouse(display_long)|uniprotkb:T-box brain protein 2(gene name synonym)|uniprotkb:Eomes(gene name)|psi-mi:Eomes(display_short)|uniprotkb:Tbr2(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637923|imex:IM-25642-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032446(gene)|ensembl:ENSMUST00000035020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001947"(heart looping)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002302"(CD8-positive, alpha-beta T cell differentiation involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR032385|interpro:IPR036960|interpro:IPR001699(Transcription factor, T-box)|refseq:NP_001158261.1|refseq:NP_034266.2	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	-	-	-	figure legend:4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:81GrRGyDRVgAxsVKQHMhpQ0D+nI10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:LAH9fYPsGnVJwECbM52cI7H0d/g	false	glutathione s tranferase tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02591	uniprotkb:P20293	intact:EBI-7457485|intact:MINT-4998459|ensembl:ENSMUSP00000021513	intact:EBI-13637160|ensembl:ENSMUSP00000074236	psi-mi:gsc_mouse(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short)	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638116|imex:IM-25642-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034481.1|ensembl:ENSMUSG00000021095(gene)|ensembl:ENSMUST00000021513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q02591	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	-	comment:mint|function:Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like activity when transplanted into Xenopus embryos	-	figure legend:4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:JP8dHDpRfNvyjVVZh5foSMbWxyg10090	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rigid:ajWAKmfWtOLCxnU1UL/+LDRapyE	false	ha tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02591	uniprotkb:P70324	intact:EBI-7457485|intact:MINT-4998459|ensembl:ENSMUSP00000021513	intact:EBI-13637323|ensembl:ENSMUSP00000018748|uniprotkb:E9QM97|uniprotkb:Q60708|uniprotkb:Q8BWH7	psi-mi:gsc_mouse(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short)	psi-mi:tbx3_mouse(display_long)|uniprotkb:Tbx3(gene name)|psi-mi:Tbx3(display_short)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638130|imex:IM-25642-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034481.1|ensembl:ENSMUSG00000021095(gene)|ensembl:ENSMUST00000021513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q02591	ensembl:ENSMUSG00000018604(gene)|ensembl:ENSMUST00000018748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021761"(limbic system development)|go:"GO:0030539"(male genitalia development)|go:"GO:0030540"(female genitalia development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046884"(follicle-stimulating hormone secretion)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0032275"(luteinizing hormone secretion)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060596"(mammary placode formation)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072105"(ureteric peristalsis)|go:"GO:0090398"(cellular senescence)|go:"GO:1905072"(cardiac jelly development)|go:"GO:1905222"(atrioventricular canal morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000137"(negative regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR022582|interpro:IPR036960|refseq:NP_035665.2|refseq:XP_006530339.1	-	comment:mint|function:Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like activity when transplanted into Xenopus embryos	-	figure legend:4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:JP8dHDpRfNvyjVVZh5foSMbWxyg10090	rogid:szp3PNpy0hHRHc/hGmDAGnxouhA10090	rigid:4SarTxsXfWQW4K9KLNV6cEbDjvA	false	ha tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02591	uniprotkb:P70327	intact:EBI-7457485|intact:MINT-4998459|ensembl:ENSMUSP00000021513	intact:EBI-13637402|ensembl:ENSMUSP00000091579|uniprotkb:B2RU37|uniprotkb:Q5SDA2	psi-mi:gsc_mouse(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short)	psi-mi:tbx6_mouse(display_long)|uniprotkb:Tbx6(gene name)|psi-mi:Tbx6(display_short)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638138|imex:IM-25642-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034481.1|ensembl:ENSMUSG00000021095(gene)|ensembl:ENSMUST00000021513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q02591	ensembl:ENSMUSG00000030699(gene)|ensembl:ENSMUST00000094037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|go:"GO:0007417"(central nervous system development)|refseq:NP_035668.2	-	comment:mint|function:Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like activity when transplanted into Xenopus embryos	-	figure legend:4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:JP8dHDpRfNvyjVVZh5foSMbWxyg10090	rogid:2MWaNwFdyyBgd4PjovfdXbsnEuY10090	rigid:O+AaHmViJC6ly9Yr9F2D7EiTEw8	false	ha tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02591	uniprotkb:Q9ES03	intact:EBI-7457485|intact:MINT-4998459|ensembl:ENSMUSP00000021513	intact:EBI-13637441|ensembl:ENSMUSP00000052591|uniprotkb:Q9EPZ5|uniprotkb:Q9ESX1	psi-mi:gsc_mouse(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short)	psi-mi:tbx20_mouse(display_long)|uniprotkb:Tbx20(gene name)|psi-mi:Tbx20(display_short)|uniprotkb:Tbx12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13638154|imex:IM-25642-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034481.1|ensembl:ENSMUSG00000021095(gene)|ensembl:ENSMUST00000021513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q02591	ensembl:ENSMUSG00000031965(gene)|ensembl:ENSMUST00000052946(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0001947"(heart looping)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003171"(atrioventricular valve development)|go:"GO:0003175"(tricuspid valve development)|go:"GO:0003176"(aortic valve development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003193"(pulmonary valve formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035922"(foramen ovale closure)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0036306"(embryonic heart tube elongation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0006936"(muscle contraction)|go:"GO:0008015"(blood circulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0060577"(pulmonary vein morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|go:"GO:0010991"(negative regulation of SMAD protein complex assembly)|interpro:IPR036960|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0021524"(visceral motor neuron differentiation)|refseq:NP_001192014.1|refseq:NP_065242.1|refseq:NP_919239.1	-	comment:mint|function:Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like activity when transplanted into Xenopus embryos	-	figure legend:4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/01/26	2017/01/26	rogid:JP8dHDpRfNvyjVVZh5foSMbWxyg10090	rogid:gNckcLHnu8noscsWEisB7n6R+FE10090	rigid:S/XhQmNkAC4edIqomMaefPYUf1g	false	ha tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WUI0	uniprotkb:P20293	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	intact:EBI-13637160|ensembl:ENSMUSP00000074236	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637515|imex:IM-25642-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	-	comment:Nuclear protein extracts of day 4 ESC-derived embryoid bodies habe been used	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/26	2017/02/06	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	-	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WUI0	uniprotkb:P20293	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	intact:EBI-13637160|ensembl:ENSMUSP00000074236	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637525|imex:IM-25642-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	-	-	-	figure legend:1E, 2 E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/26	2017/01/26	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	glutathione s tranferase tag:n-n|sufficient binding region:86-145(IPR001356)	his tag:?-?|sufficient binding region:1-230(IPR008967)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15178	uniprotkb:Q9H2W2	intact:EBI-13637631|ensembl:ENSP00000296946|uniprotkb:E7ERD6|uniprotkb:Q4KMP4	intact:EBI-13637539|ensembl:ENSP00000355775|uniprotkb:B7ZLF9	psi-mi:tbxt_human(display_long)|uniprotkb:TBXT(gene name)|psi-mi:TBXT(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:mixl1_human(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:MIXL1(gene name)|psi-mi:MIXL1(display_short)|uniprotkb:MIXL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637534|imex:IM-25642-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6ZU8|rcsb pdb:6F59|ensembl:ENSG00000164458(gene)|ensembl:ENST00000296946(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007498"(mesoderm development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5QRF|rcsb pdb:5QRG|rcsb pdb:5QRH|rcsb pdb:5QRI|rcsb pdb:5QRJ|rcsb pdb:5QRK|rcsb pdb:5QRL|rcsb pdb:5QRM|rcsb pdb:5QRN|rcsb pdb:5QRO|rcsb pdb:5QRP|rcsb pdb:5QRQ|rcsb pdb:5QRR|rcsb pdb:5QRS|rcsb pdb:5QRT|rcsb pdb:5QRU|rcsb pdb:5QRV|rcsb pdb:5QRW|rcsb pdb:5QRX|rcsb pdb:5QRY|rcsb pdb:5QRZ|rcsb pdb:5QS0|rcsb pdb:5QS1|rcsb pdb:5QS2|rcsb pdb:5QS3|rcsb pdb:5QS4|rcsb pdb:5QS5|rcsb pdb:5QS6|rcsb pdb:5QS7|rcsb pdb:5QS8|rcsb pdb:5QS9|rcsb pdb:5QSA|rcsb pdb:5QSB|rcsb pdb:5QSC|rcsb pdb:5QSD|rcsb pdb:5QSE|rcsb pdb:5QSF|rcsb pdb:5QSG|rcsb pdb:5QSH|rcsb pdb:5QSI|go:"GO:0003007"(heart morphogenesis)|rcsb pdb:5QSJ|rcsb pdb:5QSK|rcsb pdb:5QSL|rcsb pdb:5QT0|rcsb pdb:6F58|refseq:NP_001257413.1|refseq:NP_003172.1	ensembl:ENSG00000185155(gene)|ensembl:ENST00000366810(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000382"(positive regulation of mesoderm development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|refseq:NP_001269331.1|refseq:NP_114150.1	-	-	-	figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/26	2017/01/26	rogid:YJuV5JhbuWALWWLdMI64SYnyaQk9606	rogid:pdyJz0mDrs+gJTkc0V24bDwzepY9606	rigid:wgK5hqw3U5nYmo1TajUjEnzJToo	false	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P21711	uniprotkb:P24781	intact:EBI-13637718	intact:EBI-13637686|uniprotkb:Q6IP86	psi-mi:mix1_xenla(display_long)|uniprotkb:mix-a(gene name)|psi-mi:mix-a(display_short)|uniprotkb:mix1(gene name synonym)	psi-mi:tbxt_xenla(display_long)|uniprotkb:tbxt(gene name)|psi-mi:tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:bra(gene name synonym)|uniprotkb:t(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637708|imex:IM-25642-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:NP_001081294.1|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)	go:"GO:0000578"(embryonic axis specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:NP_001084047.1|rcsb pdb:1XBR|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|interpro:IPR036960	-	-	-	figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/26	2017/01/26	rogid:psvYVDipQOzIJnXm+3s0dUBpu+A8355	rogid:BX3qvymjvkXrKpiqNiu+gA31GjU8355	rigid:xdDg459z/YnSb/sMHqGVpItIvn4	false	glutathione s tranferase tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20293	uniprotkb:Q9WUI0	intact:EBI-13637160|ensembl:ENSMUSP00000074236	intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61	psi-mi:tbxt_mouse(display_long)|uniprotkb:Tbxt(gene name)|psi-mi:Tbxt(display_short)|uniprotkb:Brachyury protein(gene name synonym)|uniprotkb:Protein T(gene name synonym)|uniprotkb:T(gene name synonym)	psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Pereira et al. (2010)	pubmed:22164283|imex:IM-25642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13637744|imex:IM-25642-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000062327(gene)|ensembl:ENSMUST00000074667(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014028"(notochord formation)|go:"GO:0022414"(reproductive process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030903"(notochord development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033335.1|refseq:XP_011244504.1|dip:DIP-61216N	ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1	go:"GO:0005634"(nucleus)	-	-	figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2017/01/26	2017/01/26	rogid:2DN/wIJIzzrkLX0hOh10vXPN40g10090	rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090	rigid:Mo5G69JsmV6B5+pKCq81aPmEFss	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)