#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q01344-2	uniprotkb:P05113	intact:EBI-15957545|ensembl:ENSP00000309196|ensembl:ENSP00000373358	intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454	psi-mi:q01344-2(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:Soluble-S1(isoform synonym)|uniprotkb:CDw125(gene name synonym)	psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Patino et al. (2011)	pubmed:22153509|doi:10.1016/j.str.2011.08.015|imex:IM-17068	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15957553|imex:IM-17068-1|dip:DIP-4996E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1759442(isoform-parent)|ensembl:ENSG00000091181(gene)|ensembl:ENST00000311981(transcript)|ensembl:ENST00000383846(transcript)	refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:C4u5gH9d9YoLuW9cgyhMJFOB6yU9606	rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606	rigid:KE5MB5uo++TaMat1yWsqOsMbPQk	false	binding-associated region:21-335	mutation disrupting interaction:110-110	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01344-2	uniprotkb:P05113	intact:EBI-15957545|ensembl:ENSP00000309196|ensembl:ENSP00000373358	intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454	psi-mi:q01344-2(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:Soluble-S1(isoform synonym)|uniprotkb:CDw125(gene name synonym)	psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Patino et al. (2011)	pubmed:22153509|doi:10.1016/j.str.2011.08.015|imex:IM-17068	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15957575|imex:IM-17068-2|dip:DIP-4996E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1759442(isoform-parent)|ensembl:ENSG00000091181(gene)|ensembl:ENST00000311981(transcript)|ensembl:ENST00000383846(transcript)	refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:C4u5gH9d9YoLuW9cgyhMJFOB6yU9606	rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606	rigid:KE5MB5uo++TaMat1yWsqOsMbPQk	false	binding-associated region:21-335	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01344-2	uniprotkb:P05113	intact:EBI-15957545|ensembl:ENSP00000309196|ensembl:ENSP00000373358	intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454	psi-mi:q01344-2(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:Soluble-S1(isoform synonym)|uniprotkb:CDw125(gene name synonym)	psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Patino et al. (2011)	pubmed:22153509|doi:10.1016/j.str.2011.08.015|imex:IM-17068	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15957595|imex:IM-17068-3|dip:DIP-4996E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1759442(isoform-parent)|ensembl:ENSG00000091181(gene)|ensembl:ENST00000311981(transcript)|ensembl:ENST00000383846(transcript)	refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:C4u5gH9d9YoLuW9cgyhMJFOB6yU9606	rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606	rigid:KE5MB5uo++TaMat1yWsqOsMbPQk	false	binding-associated region:21-335	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01344-2	uniprotkb:P05113	intact:EBI-15957545|ensembl:ENSP00000309196|ensembl:ENSP00000373358	intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454	psi-mi:q01344-2(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:Soluble-S1(isoform synonym)|uniprotkb:CDw125(gene name synonym)	psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Patino et al. (2011)	pubmed:22153509|doi:10.1016/j.str.2011.08.015|imex:IM-17068	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15957614|imex:IM-17068-4|dip:DIP-4996E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1759442(isoform-parent)|ensembl:ENSG00000091181(gene)|ensembl:ENST00000311981(transcript)|ensembl:ENST00000383846(transcript)	refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:C4u5gH9d9YoLuW9cgyhMJFOB6yU9606	rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606	rigid:KE5MB5uo++TaMat1yWsqOsMbPQk	false	binding-associated region:21-335|mutation disrupting interaction:78-78|mutation decreasing interaction:75-75|mutation decreasing interaction:80-80|mutation decreasing interaction:84-84|mutation decreasing interaction:89-89|mutation decreasing interaction:178-178|mutation decreasing interaction:203-203|mutation decreasing interaction:208-208|mutation disrupting interaction:228-228|mutation decreasing interaction:315-315|mutation disrupting interaction:43-43|mutation decreasing interaction:77-77	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)