#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13153-1	uniprotkb:Q13153-1	intact:EBI-15628682|ensembl:ENSP00000348696	intact:EBI-15628682|ensembl:ENSP00000348696	psi-mi:q13153-1(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:q13153-1(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wang et al. (2011)	pubmed:22153498|doi:10.1016/j.str.2011.10.013|imex:IM-17063	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15956793|imex:IM-17063-1|dip:DIP-67276E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1307(isoform-parent)|uniprotkb:Q13153-1(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)	intact:EBI-1307(isoform-parent)|uniprotkb:Q13153-1(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	rigid:2WRLbWktCsr6yirwmVb6EPraXDE	false	binding-associated region:249-545|mutation increasing interaction:389-389	binding-associated region:249-545|mutation increasing interaction:389-389	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15956814	uniprotkb:Q13153-1	dip:DIP-59420N	intact:EBI-15628682|ensembl:ENSP00000348696	psi-mi:paktide(display_short)|psi-mi:EBI-15956814(display_long)	psi-mi:q13153-1(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2011)	pubmed:22153498|doi:10.1016/j.str.2011.10.013|imex:IM-17063	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15956817|imex:IM-17063-2|dip:DIP-187843E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	intact:EBI-1307(isoform-parent)|uniprotkb:Q13153-1(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:dDMtl5YVK4npAW8pUoiTB3TtW7Y-2	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	rigid:gL7ZIsD6+3tvEHPDy5QPaJjF5Hw	false	-	binding-associated region:249-545	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35465	intact:EBI-15956814	intact:EBI-444379|ensembl:ENSRNOP00000045832|ensembl:ENSRNOP00000073036|uniprotkb:Q62934	dip:DIP-59420N	psi-mi:pak1_rat(display_long)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p68-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:Protein kinase MUK2(gene name synonym)|uniprotkb:Pak1(gene name)|psi-mi:Pak1(display_short)	psi-mi:paktide(display_short)|psi-mi:EBI-15956814(display_long)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2011)	pubmed:22153498|doi:10.1016/j.str.2011.10.013|imex:IM-17063	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15956836|imex:IM-17063-3|dip:DIP-187844E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	ensembl:ENSRNOG00000029784(gene)|ensembl:ENSRNOT00000049321(transcript)|ensembl:ENSRNOT00000091952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0005518"(collagen binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0005524"(ATP binding)|go:"GO:0021764"(amygdala development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061534"(gamma-aminobutyric acid secretion, neurotransmission)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061535"(glutamate secretion, neurotransmission)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098597"(observational learning)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|rcsb pdb:1E0A|reactome:R-RNO-202433|reactome:R-RNO-2029482|reactome:R-RNO-2871796|reactome:R-RNO-376172|reactome:R-RNO-389359|reactome:R-RNO-3928662|reactome:R-RNO-3928664|reactome:R-RNO-399954|reactome:R-RNO-445144|reactome:R-RNO-445355|reactome:R-RNO-5218920|reactome:R-RNO-5621575|reactome:R-RNO-5627123|reactome:R-RNO-5687128|reactome:R-RNO-8964616|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013420|reactome:R-RNO-9013423|reactome:R-RNO-9013424|rgd:3250|refseq:NP_058894.1|refseq:XP_006229814.1|refseq:XP_006229815.1|refseq:XP_006229816.1|dip:DIP-32990N	-	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:wNLimcsV++XEGSFLp+/JSDAJrps10116	rogid:dDMtl5YVK4npAW8pUoiTB3TtW7Y-2	rigid:deyTkytAxkiJ9x1AyUmLxmzEGm0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)