#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6CPM4 uniprotkb:Q6CPM4 intact:EBI-15956087|ensemblfungi:CAG99202 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956098|imex:IM-17486-1|dip:DIP-188760E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:HrnaGhYUNwbojyVMsPSExIqIVjc false sufficient binding region:1-534 sufficient binding region:1-534 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CL77 uniprotkb:Q6CPM4 intact:EBI-15928255|ensemblfungi:CAG98020 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956150|imex:IM-17486-3|dip:DIP-188766E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:9loDpOR8ZaY6oREzBlqdpZ5hS4s false sufficient binding region:1-115|35s radiolabel:?-? sufficient binding region:552-736|his tag:n-n - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q6CPB9 uniprotkb:Q6CPM4 intact:EBI-15956116|ensemblfungi:CAG99307 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:q6cpb9_klula(display_long)|uniprotkb:KLLA0_E06073g(orf name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956125|imex:IM-17486-2|dip:DIP-188763E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG99307(transcript)|ensemblfungi:KLLA0_E06073g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR017956|refseq:XP_454220.1|dip:DIP-59579N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:9J9uxsY+PJ8Y6V0psAOsr+qZyZY284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:SXpq93sFjYWDHGFHg4Jg8j0JnqY false sufficient binding region:1-328|35s radiolabel:?-? sufficient binding region:1-534|his tag:n-n - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:O94228 uniprotkb:Q6CK37 intact:EBI-15956175|uniprotkb:Q6CMX6 intact:EBI-15956201|ensemblfungi:CAG98410 psi-mi:o94228_klulc(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:KDRO_E03850(orf name) psi-mi:q6ck37_klula(display_long)|uniprotkb:KLLA0_F13816g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:28985(klulc)|taxid:28985("Kluyveromyces lactis (Yeast)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15956208|imex:IM-17486-4|dip:DIP-188765E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:6P7V|rcsb pdb:6P7X|rcsb pdb:6P7W|dip:DIP-59575N|refseq:XP_454713.1 ensemblfungi:CAG98410(transcript)|ensemblfungi:KLLA0_F13816g(gene)|rcsb pdb:6P7V|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_455702.1|dip:DIP-59578N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:NqTBO/T0fnHSNmXAT1tY2PQywbg28985 rogid:410Qqv0tP3DAOL1qSu0uvR3kzQo284590 rigid:ee1IqbOfU7sC6rJ0nD2yiFhNDQc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O94228 uniprotkb:Q6CRD4 intact:EBI-15956175|uniprotkb:Q6CMX6 intact:EBI-15956188|ensemblfungi:CAH00601 psi-mi:o94228_klulc(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:KDRO_E03850(orf name) psi-mi:q6crd4_klula(display_long)|uniprotkb:KLLA0_D09977g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:28985(klulc)|taxid:28985("Kluyveromyces lactis (Yeast)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15956208|imex:IM-17486-4|dip:DIP-188765E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:6P7V|rcsb pdb:6P7X|rcsb pdb:6P7W|dip:DIP-59575N|refseq:XP_454713.1 ensemblfungi:CAH00601(transcript)|ensemblfungi:KLLA0_D09977g(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR031760|interpro:IPR036864|rcsb pdb:6P7V|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_453505.1|dip:DIP-59577N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:NqTBO/T0fnHSNmXAT1tY2PQywbg28985 rogid:IqQbn3rfgxWi8aUeIfHOFkfncU8284590 rigid:ee1IqbOfU7sC6rJ0nD2yiFhNDQc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6CL77 uniprotkb:Q6CPM4 intact:EBI-15928255|ensemblfungi:CAG98020 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956226|imex:IM-17486-5|dip:DIP-188766E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:9loDpOR8ZaY6oREzBlqdpZ5hS4s false sufficient binding region:1-40|maltose binding protein tag:n-n binding-associated region:552-736 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6CRD4 uniprotkb:Q6CPM4 intact:EBI-15956188|ensemblfungi:CAH00601 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:q6crd4_klula(display_long)|uniprotkb:KLLA0_D09977g(orf name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956249|imex:IM-17486-6|dip:DIP-188761E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH00601(transcript)|ensemblfungi:KLLA0_D09977g(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR031760|interpro:IPR036864|rcsb pdb:6P7V|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_453505.1|dip:DIP-59577N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:IqQbn3rfgxWi8aUeIfHOFkfncU8284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:dOM2+glBXTRAmlG3OLEyDaoq6As false his tag:n-n sufficient binding region:1-100|35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CL77 uniprotkb:Q6CPM4 intact:EBI-15928255|ensemblfungi:CAG98020 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956332|imex:IM-17486-9|dip:DIP-188766E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:9loDpOR8ZaY6oREzBlqdpZ5hS4s false sufficient binding region:1-115 binding-associated region:552-736 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P49379 uniprotkb:O94228 intact:EBI-15956272|ensemblfungi:CAH02536|uniprotkb:Q6CV96 intact:EBI-15956175|uniprotkb:Q6CMX6 psi-mi:cbf1_klula(display_long)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:CPF1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:KLLA0B13761g(locus name) psi-mi:o94228_klulc(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:KDRO_E03850(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:28985(klulc)|taxid:28985("Kluyveromyces lactis (Yeast)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15956312|imex:IM-17486-8|dip:DIP-188764E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH02536(transcript)|ensemblfungi:KLLA0_B13761g(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_452143.1|dip:DIP-59576N go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:6P7V|rcsb pdb:6P7X|rcsb pdb:6P7W|dip:DIP-59575N|refseq:XP_454713.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Jrik2m0BV2FJkXsOKf8hBEnei1I284590 rogid:NqTBO/T0fnHSNmXAT1tY2PQywbg28985 rigid:WTkDCsh6uAaeztN3m87Y9EKZpAk false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P49379 uniprotkb:Q6CK37 intact:EBI-15956272|ensemblfungi:CAH02536|uniprotkb:Q6CV96 intact:EBI-15956201|ensemblfungi:CAG98410 psi-mi:cbf1_klula(display_long)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:CPF1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:KLLA0B13761g(locus name) psi-mi:q6ck37_klula(display_long)|uniprotkb:KLLA0_F13816g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15956312|imex:IM-17486-8|dip:DIP-188764E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH02536(transcript)|ensemblfungi:KLLA0_B13761g(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_452143.1|dip:DIP-59576N ensemblfungi:CAG98410(transcript)|ensemblfungi:KLLA0_F13816g(gene)|rcsb pdb:6P7V|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_455702.1|dip:DIP-59578N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Jrik2m0BV2FJkXsOKf8hBEnei1I284590 rogid:410Qqv0tP3DAOL1qSu0uvR3kzQo284590 rigid:WTkDCsh6uAaeztN3m87Y9EKZpAk false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P49379 uniprotkb:Q6CPM4 intact:EBI-15956272|ensemblfungi:CAH02536|uniprotkb:Q6CV96 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:cbf1_klula(display_long)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:CPF1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:KLLA0B13761g(locus name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15956312|imex:IM-17486-8|dip:DIP-188764E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH02536(transcript)|ensemblfungi:KLLA0_B13761g(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_452143.1|dip:DIP-59576N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Jrik2m0BV2FJkXsOKf8hBEnei1I284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:WTkDCsh6uAaeztN3m87Y9EKZpAk false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P49379 uniprotkb:Q6CRD4 intact:EBI-15956272|ensemblfungi:CAH02536|uniprotkb:Q6CV96 intact:EBI-15956188|ensemblfungi:CAH00601 psi-mi:cbf1_klula(display_long)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:CPF1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:KLLA0B13761g(locus name) psi-mi:q6crd4_klula(display_long)|uniprotkb:KLLA0_D09977g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15956312|imex:IM-17486-8|dip:DIP-188764E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH02536(transcript)|ensemblfungi:KLLA0_B13761g(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_452143.1|dip:DIP-59576N ensemblfungi:CAH00601(transcript)|ensemblfungi:KLLA0_D09977g(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR031760|interpro:IPR036864|rcsb pdb:6P7V|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_453505.1|dip:DIP-59577N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Jrik2m0BV2FJkXsOKf8hBEnei1I284590 rogid:IqQbn3rfgxWi8aUeIfHOFkfncU8284590 rigid:WTkDCsh6uAaeztN3m87Y9EKZpAk false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P49379 uniprotkb:Q6CPM4 intact:EBI-15956272|ensemblfungi:CAH02536|uniprotkb:Q6CV96 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:cbf1_klula(display_long)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:CPF1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:KLLA0B13761g(locus name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956289|imex:IM-17486-7|dip:DIP-188762E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH02536(transcript)|ensemblfungi:KLLA0_B13761g(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_452143.1|dip:DIP-59576N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Jrik2m0BV2FJkXsOKf8hBEnei1I284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:oeuhfcMF6eI2Nlz8Buqs8R/wEkQ false 35s radiolabel:?-?|sufficient binding region:229-359 his tag:n-n - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P49379 uniprotkb:Q6CPM4 intact:EBI-15956272|ensemblfungi:CAH02536|uniprotkb:Q6CV96 intact:EBI-15956087|ensemblfungi:CAG99202 psi-mi:cbf1_klula(display_long)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:CPF1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:KLLA0B13761g(locus name) psi-mi:q6cpm4_klula(display_long)|uniprotkb:KLLA0_E03807g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:22139014|doi:10.1038/nsmb.2178|imex:IM-17486 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15956353|imex:IM-17486-10|dip:DIP-188762E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH02536(transcript)|ensemblfungi:KLLA0_B13761g(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:XP_452143.1|dip:DIP-59576N ensemblfungi:CAG99202(transcript)|ensemblfungi:KLLA0_E03807g(gene)|go:"GO:0003677"(DNA binding)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:3SQI|rcsb pdb:3T79|rcsb pdb:6P7W|rcsb pdb:6P7X|refseq:XP_454115.1|dip:DIP-59574N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Jrik2m0BV2FJkXsOKf8hBEnei1I284590 rogid:igeSoibocTEhlJ6Iph0h74okKHU284590 rigid:oeuhfcMF6eI2Nlz8Buqs8R/wEkQ false 35s radiolabel:?-? sufficient binding region:1-403|his tag:n-n - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)