#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15955174|imex:IM-17076-1|dip:DIP-187971E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:KwmZu+BWQs6I8laFkPR3W0owV5o false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41182 uniprotkb:P63208-1 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-307497|uniprotkb:P34991-1|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:p63208-1(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955263|imex:IM-17076-5|dip:DIP-187972E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 intact:EBI-307486(skp1_human)|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000517625(transcript)|ensembl:ENST00000522855(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:0LjdsWuj+kAeB9PCkMXmuvCgRKw false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41182 uniprotkb:Q13616 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955263|imex:IM-17076-5|dip:DIP-187972E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:0LjdsWuj+kAeB9PCkMXmuvCgRKw false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41182 uniprotkb:Q86XK2 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955263|imex:IM-17076-5|dip:DIP-187972E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rigid:0LjdsWuj+kAeB9PCkMXmuvCgRKw false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P63208-1 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-307497|uniprotkb:P34991-1|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:p63208-1(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955236|imex:IM-17076-4|dip:DIP-187972E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 intact:EBI-307486(skp1_human)|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000517625(transcript)|ensembl:ENST00000522855(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:0LjdsWuj+kAeB9PCkMXmuvCgRKw false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:Q13616 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955236|imex:IM-17076-4|dip:DIP-187972E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:0LjdsWuj+kAeB9PCkMXmuvCgRKw false flag tag:n-n myc tag:n-n|binding-associated region:1-242 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955236|imex:IM-17076-4|dip:DIP-187972E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:0LjdsWuj+kAeB9PCkMXmuvCgRKw false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955212|imex:IM-17076-3|dip:DIP-187971E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:KwmZu+BWQs6I8laFkPR3W0owV5o false flag tag:n-n|necessary binding region:585-746 ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955195|imex:IM-17076-2|dip:DIP-187971E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:KwmZu+BWQs6I8laFkPR3W0owV5o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7TPD1 uniprotkb:P41183 intact:EBI-15955324|ensembl:ENSMUSP00000005504|uniprotkb:A1A595|uniprotkb:E9QP06|uniprotkb:Q08EB9|uniprotkb:Q08EC0|uniprotkb:Q80UP0 intact:EBI-6253762|ensembl:ENSMUSP00000023151|uniprotkb:Q61065 psi-mi:fbx11_mouse(display_long)|uniprotkb:Fbxo11(gene name)|psi-mi:Fbxo11(display_short) psi-mi:bcl6_mouse(display_long)|uniprotkb:Bcl6(gene name)|psi-mi:Bcl6(display_short)|uniprotkb:Bcl-6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955401|imex:IM-17076-10|dip:DIP-187976E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000005371(gene)|ensembl:ENSMUST00000005504(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001074503.1|refseq:XP_006524267.1|refseq:NP_001335177.1|dip:DIP-59433N ensembl:ENSMUSG00000022508(gene)|ensembl:ENSMUST00000023151(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_033874.1|refseq:NP_001334955.1|refseq:XP_017172344.1|dip:DIP-59432N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:ptgqwF6rsnXuDEz59Gcqg4JN2yk10090 rogid:8RV9ZxrCI7Yr24uQQCh2wahGo5o10090 rigid:scuLSGu1SIMxjjjQ5rWBeYlEduo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955380|imex:IM-17076-9|dip:DIP-187971E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:KwmZu+BWQs6I8laFkPR3W0owV5o false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TPD1 uniprotkb:P41183 intact:EBI-15955324|ensembl:ENSMUSP00000005504|uniprotkb:A1A595|uniprotkb:E9QP06|uniprotkb:Q08EB9|uniprotkb:Q08EC0|uniprotkb:Q80UP0 intact:EBI-6253762|ensembl:ENSMUSP00000023151|uniprotkb:Q61065 psi-mi:fbx11_mouse(display_long)|uniprotkb:Fbxo11(gene name)|psi-mi:Fbxo11(display_short) psi-mi:bcl6_mouse(display_long)|uniprotkb:Bcl6(gene name)|psi-mi:Bcl6(display_short)|uniprotkb:Bcl-6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955363|imex:IM-17076-8|dip:DIP-187976E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000005371(gene)|ensembl:ENSMUST00000005504(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001074503.1|refseq:XP_006524267.1|refseq:NP_001335177.1|dip:DIP-59433N ensembl:ENSMUSG00000022508(gene)|ensembl:ENSMUST00000023151(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_033874.1|refseq:NP_001334955.1|refseq:XP_017172344.1|dip:DIP-59432N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:ptgqwF6rsnXuDEz59Gcqg4JN2yk10090 rogid:8RV9ZxrCI7Yr24uQQCh2wahGo5o10090 rigid:scuLSGu1SIMxjjjQ5rWBeYlEduo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955303|imex:IM-17076-7|dip:DIP-187971E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:KwmZu+BWQs6I8laFkPR3W0owV5o false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:Q13616 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955418|imex:IM-17076-11|dip:DIP-187974E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:XzstepT1zVM0ZY/haN0QYQ6x5Pc false flag tag:n-n myc tag:n-n|binding-associated region:1-242 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955418|imex:IM-17076-11|dip:DIP-187974E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:XzstepT1zVM0ZY/haN0QYQ6x5Pc false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63208-1 uniprotkb:Q86XK2 intact:EBI-307497|uniprotkb:P34991-1|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 psi-mi:p63208-1(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955284|imex:IM-17076-6|dip:DIP-86195E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-307486(skp1_human)|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000517625(transcript)|ensembl:ENST00000522855(transcript) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rigid:56Xw9absq3Tg4AlID9vvtSAPWGQ false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-4399559 uniprotkb:P41182 dip:DIP-24261N intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15955471|imex:IM-17076-13|dip:DIP-187975E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:svO/jDeck0DTigy3xtWTESJRYMw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P63208-1 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-307497|uniprotkb:P34991-1|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:p63208-1(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955444|imex:IM-17076-12|dip:DIP-187973E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 intact:EBI-307486(skp1_human)|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000517625(transcript)|ensembl:ENST00000522855(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:YU5vx5GLmXwPk8RPop73zmtI4pU false flag tag:n-n|sufficient binding region:1-584,747-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:Q13616 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955444|imex:IM-17076-12|dip:DIP-187973E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:YU5vx5GLmXwPk8RPop73zmtI4pU false flag tag:n-n|sufficient binding region:1-584,747-c myc tag:n-n|binding-associated region:1-242 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P62877 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955488|imex:IM-17076-14|dip:DIP-187977E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606 rigid:chiGxfFxGiwvYuD1MuTIsRrGLqo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P63208-1 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-307497|uniprotkb:P34991-1|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:p63208-1(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955488|imex:IM-17076-14|dip:DIP-187977E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 intact:EBI-307486(skp1_human)|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000517625(transcript)|ensembl:ENST00000522855(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:chiGxfFxGiwvYuD1MuTIsRrGLqo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:Q13616 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955488|imex:IM-17076-14|dip:DIP-187977E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:chiGxfFxGiwvYuD1MuTIsRrGLqo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:P41182 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-765407|uniprotkb:A7E241|uniprotkb:D3DNV5|uniprotkb:B8PSA7|ensembl:ENSP00000232014|ensembl:ENSP00000384371 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duan et al. (2012) pubmed:22113614|doi:10.1038/nature10688|imex:IM-17076 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15955488|imex:IM-17076-14|dip:DIP-187977E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_011511364.1|refseq:XP_005247751.1|dip:DIP-2651N|ensembl:ENSG00000113916(gene)|ensembl:ENST00000232014(transcript)|ensembl:ENST00000406870(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042092"(type 2 immune response)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043380"(regulation of memory T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EN2|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606 rigid:chiGxfFxGiwvYuD1MuTIsRrGLqo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)