#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5I0H3	uniprotkb:P42260	intact:EBI-7253100|intact:MINT-4651872|ensembl:ENSRNOP00000022048	intact:EBI-7809795|ensembl:ENSRNOP00000068172|intact:MINT-8359884	psi-mi:sumo1_rat(display_long)|uniprotkb:Sumo1(gene name)|psi-mi:Sumo1(display_short)	psi-mi:grik2_rat(display_long)|uniprotkb:Grik2(gene name)|psi-mi:Grik2(display_short)|uniprotkb:Glur6(gene name synonym)|uniprotkb:Glutamate receptor 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Konopacki et al. (2011)	pubmed:22089239|doi:"https://doi.org/10.1073/pnas.1111575108"|imex:IM-21346	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953917|imex:IM-21346-1|dip:DIP-191517E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1306919|refseq:NP_001009672.1|ensembl:ENSRNOG00000016133(gene)|ensembl:ENSRNOT00000022047(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030578"(PML body organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:Q5I0H3|reactome:R-RNO-3065676|reactome:R-RNO-3065678|reactome:R-RNO-3065679|reactome:R-RNO-3108214|reactome:R-RNO-3108232|reactome:R-RNO-3232118|reactome:R-RNO-3232142|reactome:R-RNO-3899300|reactome:R-RNO-4085377|reactome:R-RNO-4090294|reactome:R-RNO-4551638|reactome:R-RNO-4570464|reactome:R-RNO-4615885|reactome:R-RNO-4655427|reactome:R-RNO-4755510|reactome:R-RNO-5693565|reactome:R-RNO-5693571|reactome:R-RNO-5693607|reactome:R-RNO-5696395|reactome:R-RNO-69473|reactome:R-RNO-877312|reactome:R-RNO-8866904|reactome:R-RNO-9615933|dip:DIP-46501N	ensembl:ENSRNOG00000000368(gene)|ensembl:ENSRNOT00000076234(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S50|rcsb pdb:1S7Y|rcsb pdb:1S9T|rcsb pdb:1SD3|rcsb pdb:1TT1|rcsb pdb:1YAE|rcsb pdb:2I0B|rcsb pdb:2I0C|rcsb pdb:2XXR|rcsb pdb:2XXT|rcsb pdb:2XXU|rcsb pdb:2XXV|rcsb pdb:2XXW|rcsb pdb:2XXX|rcsb pdb:2XXY|rcsb pdb:3G3F|rcsb pdb:3G3G|rcsb pdb:3G3H|rcsb pdb:3G3I|rcsb pdb:3G3J|rcsb pdb:3G3K|rcsb pdb:3H6G|rcsb pdb:3H6H|rcsb pdb:3QLT|rcsb pdb:3QLU|rcsb pdb:3QLV|rcsb pdb:4BDL|rcsb pdb:4BDM|rcsb pdb:4BDN|rcsb pdb:4BDO|rcsb pdb:4BDQ|rcsb pdb:4BDR|rcsb pdb:4H8I|rcsb pdb:4UQQ|rcsb pdb:5CMK|rcsb pdb:5CMM|rcsb pdb:5KUF|rcsb pdb:5KUH|rcsb pdb:7KS0|rcsb pdb:7KS3|reactome:R-RNO-451307|reactome:R-RNO-451308|refseq:NP_062182.1|rgd:2733|dip:DIP-29256N	psi-mi:"MI:0465"(dip)	comment:mint|function:Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	-	2017/08/07	2017/08/10	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ10116	rogid:0Eh9oL6GX10ePstSVMv0PpRnFWQ10116	rigid:PGpL1DSJfRRgGdYeS5QR0dDAN5Y	false	-	mutation disrupting interaction strength:886-886|yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)