#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03372-1	uniprotkb:Q92993	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953345|imex:IM-17094-2|dip:DIP-188051E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rigid:e792mpXyZMjodeXmmYLpfZEn67k	false	sufficient binding region:282-595	flag tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03372-1	uniprotkb:Q92993	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953320|imex:IM-17094-1|dip:DIP-188051E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rigid:e792mpXyZMjodeXmmYLpfZEn67k	false	binding-associated region:282-595	flag tag:n-n|mutation disrupting interaction:493-493,492-492	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15634422	uniprotkb:Q92993	dip:DIP-29329N	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953419|imex:IM-17094-5|dip:DIP-188052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rigid:kfKmz6ZkuIpZ1i37JiwCvjqFr3E	false	N6-methyl-L-lysine:4-4|biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4	flag tag:n-n|binding-associated region:1-160	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-15634422	uniprotkb:Q92993	dip:DIP-29329N	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953446|imex:IM-17094-6|dip:DIP-188052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rigid:kfKmz6ZkuIpZ1i37JiwCvjqFr3E	false	N6-methyl-L-lysine:4-4|biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4	flag tag:n-n|mutation disrupting interaction:26-26|mutation disrupting interaction:43-43|mutation disrupting interaction:47-47|mutation disrupting interaction:50-50|sufficient binding region:1-160	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03372-1	uniprotkb:Q92993	intact:EBI-15606245|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:p03372-1(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)|uniprotkb:ER66(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:hER-alpha66(isoform synonym)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953395|imex:IM-17094-4|dip:DIP-188051E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78473(isoform-parent)|ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/07	2017/08/10	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rigid:e792mpXyZMjodeXmmYLpfZEn67k	false	-	flag tag:n-n|mutation disrupting interaction:493-493,492-492	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03164	intact:EBI-15634422	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	dip:DIP-29329N	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953368|imex:IM-17094-3|dip:DIP-188053E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	-	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2	rigid:k2KjSgu6SO9itgdZyvIQspmf3fM	false	binding-associated region:1067-1989|flag tag:n-n	N6,N6,N6-trimethyl-L-lysine:4-4|biotin tag:0-0|N6,N6-dimethyl-L-lysine:4-4	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-15634422	uniprotkb:Q92993	dip:DIP-29329N	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:h3k9-2(display_short)|psi-mi:EBI-15634422(display_long)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Jeong et al. (2011)	pubmed:22081016|doi:10.1038/nsmb.2153|imex:IM-17094	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15953485|imex:IM-17094-7|dip:DIP-188052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-2	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rigid:kfKmz6ZkuIpZ1i37JiwCvjqFr3E	false	N6-methyl-L-lysine:4-4	binding-associated region:1-160	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)