#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y3Z3 uniprotkb:Q9Y3Z3 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Goldstone et al. (2011) pubmed:22056990|doi:10.1038/nature10623|imex:IM-17082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15952340|imex:IM-17082-1|dip:DIP-187992E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:IFqhIzhhutUyqghaudcjPZmTLVs false binding-associated region:120-626 binding-associated region:120-626 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3Z3 uniprotkb:Q9Y3Z3 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Goldstone et al. (2011) pubmed:22056990|doi:10.1038/nature10623|imex:IM-17082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15952377|imex:IM-17082-3|dip:DIP-187992E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:IFqhIzhhutUyqghaudcjPZmTLVs false binding-associated region:26-583 binding-associated region:26-583 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3Z3 uniprotkb:Q9Y3Z3 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0067"(light scattering) Goldstone et al. (2011) pubmed:22056990|doi:10.1038/nature10623|imex:IM-17082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15952395|imex:IM-17082-4|dip:DIP-187992E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:IFqhIzhhutUyqghaudcjPZmTLVs false binding-associated region:120-626 binding-associated region:120-626 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3Z3 uniprotkb:Q9Y3Z3 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Goldstone et al. (2011) pubmed:22056990|doi:10.1038/nature10623|imex:IM-17082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15952359|imex:IM-17082-2|dip:DIP-187992E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:IFqhIzhhutUyqghaudcjPZmTLVs false binding-associated region:120-626 binding-associated region:120-626 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3Z3 uniprotkb:Q9Y3Z3 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Goldstone et al. (2011) pubmed:22056990|doi:10.1038/nature10623|imex:IM-17082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15952413|imex:IM-17082-5|dip:DIP-187992E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:IFqhIzhhutUyqghaudcjPZmTLVs false binding-associated region:120-626 binding-associated region:120-626 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)