#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q786F2 uniprotkb:Q96NY8 intact:EBI-5323300 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:hema_measc(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:0047"(far western blotting) Mühlebach et al. (2011) pubmed:22048310|doi:10.1038/nature10639|imex:IM-17079 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15950544|imex:IM-17079-1|dip:DIP-187980E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056923.1|dip:DIP-59438N|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|interpro:IPR000665(Haemagglutinin-neuraminidase glycoprotein)|interpro:IPR036278|rcsb pdb:4GJT refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:VFL00owFf+IDb4leUQ6faTfvIa4645098 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:Hvux7bR/4kbJPhKmcWNdQHYHI/Q false binding-associated region:60-617 sufficient binding region:1-141 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q786F2 uniprotkb:Q96NY8 intact:EBI-5323300 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:hema_measc(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Mühlebach et al. (2011) pubmed:22048310|doi:10.1038/nature10639|imex:IM-17079 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15950565|imex:IM-17079-2|dip:DIP-187980E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056923.1|dip:DIP-59438N|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|interpro:IPR000665(Haemagglutinin-neuraminidase glycoprotein)|interpro:IPR036278|rcsb pdb:4GJT refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:VFL00owFf+IDb4leUQ6faTfvIa4645098 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:Hvux7bR/4kbJPhKmcWNdQHYHI/Q false binding-associated region:60-617 binding-associated region:1-331 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q786F2 uniprotkb:Q96NY8 intact:EBI-5323300 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:hema_measc(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:0047"(far western blotting) Mühlebach et al. (2011) pubmed:22048310|doi:10.1038/nature10639|imex:IM-17079 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15950586|imex:IM-17079-3|dip:DIP-187980E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056923.1|dip:DIP-59438N|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|interpro:IPR000665(Haemagglutinin-neuraminidase glycoprotein)|interpro:IPR036278|rcsb pdb:4GJT refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:VFL00owFf+IDb4leUQ6faTfvIa4645098 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:Hvux7bR/4kbJPhKmcWNdQHYHI/Q false binding-associated region:60-617 sufficient binding region:1-141 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13291 uniprotkb:Q786F2 intact:EBI-4315002|uniprotkb:Q5W172|uniprotkb:Q9HBE8|uniprotkb:W0HKK7|ensembl:ENSP00000306190 intact:EBI-5323300 psi-mi:slaf1_human(display_long)|uniprotkb:SLAMF1(gene name)|psi-mi:SLAMF1(display_short)|uniprotkb:SLAM family member 1(gene name synonym)|uniprotkb:SLAM(gene name synonym)|uniprotkb:CDw150(gene name synonym)|uniprotkb:IPO-3(gene name synonym) psi-mi:hema_measc(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short) psi-mi:"MI:0047"(far western blotting) Mühlebach et al. (2011) pubmed:22048310|doi:10.1038/nature10639|imex:IM-17079 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:645098(measc)|taxid:645098("measles virus (strai") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15950607|imex:IM-17079-4|dip:DIP-187981E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005245513.1|refseq:NP_003028.1|refseq:NP_001317683.1|ensembl:ENSG00000117090(gene)|ensembl:ENST00000302035(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001779"(natural killer cell differentiation)|interpro:IPR036179|rcsb pdb:1D4T|rcsb pdb:1D4W|rcsb pdb:1I3Z|rcsb pdb:1KA6|rcsb pdb:1KA7|rcsb pdb:1M27|rcsb pdb:2DZF|rcsb pdb:2IE9|rcsb pdb:2IFL|rcsb pdb:2IG5|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0003823"(antigen binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010407(Signaling lymphocytic activation molecule, N-terminal)|go:"GO:0001787"(natural killer cell proliferation)|dip:DIP-40767N refseq:NP_056923.1|dip:DIP-59438N|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|interpro:IPR000665(Haemagglutinin-neuraminidase glycoprotein)|interpro:IPR036278|rcsb pdb:4GJT psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:DduZeT4BxhSno9xA/om9mkV1rpI9606 rogid:VFL00owFf+IDb4leUQ6faTfvIa4645098 rigid:iZYTyY2O8/YEh+++fb5zoDD+uXY false binding-associated region:21-230 binding-associated region:60-617 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13291 uniprotkb:Q786F2 intact:EBI-4315002|uniprotkb:Q5W172|uniprotkb:Q9HBE8|uniprotkb:W0HKK7|ensembl:ENSP00000306190 intact:EBI-5323300 psi-mi:slaf1_human(display_long)|uniprotkb:SLAMF1(gene name)|psi-mi:SLAMF1(display_short)|uniprotkb:SLAM family member 1(gene name synonym)|uniprotkb:SLAM(gene name synonym)|uniprotkb:CDw150(gene name synonym)|uniprotkb:IPO-3(gene name synonym) psi-mi:hema_measc(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Mühlebach et al. (2011) pubmed:22048310|doi:10.1038/nature10639|imex:IM-17079 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:645098(measc)|taxid:645098("measles virus (strai") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15950628|imex:IM-17079-5|dip:DIP-187981E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005245513.1|refseq:NP_003028.1|refseq:NP_001317683.1|ensembl:ENSG00000117090(gene)|ensembl:ENST00000302035(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001779"(natural killer cell differentiation)|interpro:IPR036179|rcsb pdb:1D4T|rcsb pdb:1D4W|rcsb pdb:1I3Z|rcsb pdb:1KA6|rcsb pdb:1KA7|rcsb pdb:1M27|rcsb pdb:2DZF|rcsb pdb:2IE9|rcsb pdb:2IFL|rcsb pdb:2IG5|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0003823"(antigen binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010407(Signaling lymphocytic activation molecule, N-terminal)|go:"GO:0001787"(natural killer cell proliferation)|dip:DIP-40767N refseq:NP_056923.1|dip:DIP-59438N|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|interpro:IPR000665(Haemagglutinin-neuraminidase glycoprotein)|interpro:IPR036278|rcsb pdb:4GJT psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:DduZeT4BxhSno9xA/om9mkV1rpI9606 rogid:VFL00owFf+IDb4leUQ6faTfvIa4645098 rigid:iZYTyY2O8/YEh+++fb5zoDD+uXY false binding-associated region:21-230 binding-associated region:60-617 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)