#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O66659 uniprotkb:O66659 intact:EBI-15590648|ensemblbacteria:AAC06612 intact:EBI-15590648|ensemblbacteria:AAC06612 psi-mi:dnaa_aquae(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:aq_322(locus name) psi-mi:dnaa_aquae(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:aq_322(locus name) psi-mi:"MI:0030"(cross-linking study) Duderstadt et al. (2011) pubmed:21964332|doi:10.1038/nature10455|imex:IM-16192 taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15946089|imex:IM-16192-1|dip:DIP-57238E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC06612(transcript)|ensemblbacteria:aq_322(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR027417|rcsb pdb:1L8Q|rcsb pdb:2HCB|rcsb pdb:3R8F|refseq:NP_213219.1|refseq:WP_010880157.1|dip:DIP-29219N ensemblbacteria:AAC06612(transcript)|ensemblbacteria:aq_322(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR027417|rcsb pdb:1L8Q|rcsb pdb:2HCB|rcsb pdb:3R8F|refseq:NP_213219.1|refseq:WP_010880157.1|dip:DIP-29219N psi-mi:"MI:0465"(dip) crc64:C641CB199AA79906 crc64:C641CB199AA79906 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:EScwrT1MHpbXTxxgKwaLVI3fraw224324 rogid:EScwrT1MHpbXTxxgKwaLVI3fraw224324 rigid:MNIC8ZEB39xBMUnhZDdKu2EXm3c false binding-associated region:76-399 binding-associated region:76-399 - 0 psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:O66659 uniprotkb:O66659 intact:EBI-15590648|ensemblbacteria:AAC06612 intact:EBI-15590648|ensemblbacteria:AAC06612 psi-mi:dnaa_aquae(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:aq_322(locus name) psi-mi:dnaa_aquae(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:aq_322(locus name) psi-mi:"MI:0114"(x-ray crystallography) Duderstadt et al. (2011) pubmed:21964332|doi:10.1038/nature10455|imex:IM-16192 taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") taxid:224324(aquae)|taxid:224324("Aquifex aeolicus (strain VF5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15946108|imex:IM-16192-2|dip:DIP-57238E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC06612(transcript)|ensemblbacteria:aq_322(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR027417|rcsb pdb:1L8Q|rcsb pdb:2HCB|rcsb pdb:3R8F|refseq:NP_213219.1|refseq:WP_010880157.1|dip:DIP-29219N ensemblbacteria:AAC06612(transcript)|ensemblbacteria:aq_322(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR027417|rcsb pdb:1L8Q|rcsb pdb:2HCB|rcsb pdb:3R8F|refseq:NP_213219.1|refseq:WP_010880157.1|dip:DIP-29219N psi-mi:"MI:0465"(dip) crc64:C641CB199AA79906 crc64:C641CB199AA79906 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:EScwrT1MHpbXTxxgKwaLVI3fraw224324 rogid:EScwrT1MHpbXTxxgKwaLVI3fraw224324 rigid:MNIC8ZEB39xBMUnhZDdKu2EXm3c false binding-associated region:76-399 binding-associated region:76-399 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)