#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12159 uniprotkb:P39081 intact:EBI-29516|uniprotkb:D6VT14|ensemblfungi:YDR381W intact:EBI-12980|uniprotkb:Q04932|uniprotkb:D6VSL0|ensemblfungi:YDR228C psi-mi:yra1_yeast(display_long)|uniprotkb:YRA1(gene name)|psi-mi:YRA1(display_short)|uniprotkb:D9481.2(orf name)|uniprotkb:D9509.1(orf name)|uniprotkb:YDR381W(locus name) psi-mi:pcf11_yeast(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:YDR228C(locus name)|uniprotkb:YD9934.13C(orf name)|uniprotkb:protein 1 of CF I(gene name synonym) psi-mi:"MI:0096"(pull down) Johnson et al. (2011) pubmed:21947206|doi:10.1038/nsmb.2126|imex:IM-17085 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15945817|imex:IM-17085-1|dip:DIP-187994E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010669.1|sgd:S000002789|dip:DIP-1791N|mint:Q12159|ensemblfungi:YDR381W(gene)|ensemblfungi:YDR381W_mRNA(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:1902281"(negative regulation of RNA helicase activity)|go:"GO:1990119"(RNA helicase inhibitor activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034357|interpro:IPR035979|rcsb pdb:5SUP sgd:S000002636|ensemblfungi:YDR228C(gene)|ensemblfungi:YDR228C_mRNA(transcript)|refseq:NP_010514.3|go:"GO:0000993"(RNA polymerase II complex binding)|dip:DIP-944N|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|rcsb pdb:1SZ9|rcsb pdb:1SZA|rcsb pdb:2BF0|rcsb pdb:2NAX|rcsb pdb:2NPI|rcsb pdb:4C0B|rcsb pdb:4C0H|rcsb pdb:4OI4|rcsb pdb:5M9Z psi-mi:"MI:0465"(dip) crc64:480B5B6DC0D14BE9 crc64:66F91BA9577E82F1 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:pLiU4X4uQRi7nw6fxaSJW7Ppum4559292 rogid:NT0NGp2ly1eBgnP0a3SbaAxU0ok559292 rigid:YyNBNcuSWwsGrVRtsfIZCbAVSOI false glutathione s tranferase tag:n-n binding-associated region:420-608|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12159 uniprotkb:P39081 intact:EBI-29516|uniprotkb:D6VT14|ensemblfungi:YDR381W intact:EBI-12980|uniprotkb:Q04932|uniprotkb:D6VSL0|ensemblfungi:YDR228C psi-mi:yra1_yeast(display_long)|uniprotkb:YRA1(gene name)|psi-mi:YRA1(display_short)|uniprotkb:D9481.2(orf name)|uniprotkb:D9509.1(orf name)|uniprotkb:YDR381W(locus name) psi-mi:pcf11_yeast(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:YDR228C(locus name)|uniprotkb:YD9934.13C(orf name)|uniprotkb:protein 1 of CF I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Johnson et al. (2011) pubmed:21947206|doi:10.1038/nsmb.2126|imex:IM-17085 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15945859|imex:IM-17085-3|dip:DIP-187995E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010669.1|sgd:S000002789|dip:DIP-1791N|mint:Q12159|ensemblfungi:YDR381W(gene)|ensemblfungi:YDR381W_mRNA(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:1902281"(negative regulation of RNA helicase activity)|go:"GO:1990119"(RNA helicase inhibitor activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034357|interpro:IPR035979|rcsb pdb:5SUP sgd:S000002636|ensemblfungi:YDR228C(gene)|ensemblfungi:YDR228C_mRNA(transcript)|refseq:NP_010514.3|go:"GO:0000993"(RNA polymerase II complex binding)|dip:DIP-944N|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|rcsb pdb:1SZ9|rcsb pdb:1SZA|rcsb pdb:2BF0|rcsb pdb:2NAX|rcsb pdb:2NPI|rcsb pdb:4C0B|rcsb pdb:4C0H|rcsb pdb:4OI4|rcsb pdb:5M9Z psi-mi:"MI:0465"(dip) crc64:480B5B6DC0D14BE9 crc64:66F91BA9577E82F1 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:pLiU4X4uQRi7nw6fxaSJW7Ppum4559292 rogid:NT0NGp2ly1eBgnP0a3SbaAxU0ok559292 rigid:+Ae2JfVLs2fnCXo18wY4z3WnRGw false - ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12159 uniprotkb:Q07478 intact:EBI-29516|uniprotkb:D6VT14|ensemblfungi:YDR381W intact:EBI-18500|ensemblfungi:YDL084W|uniprotkb:D6VRR5 psi-mi:yra1_yeast(display_long)|uniprotkb:YRA1(gene name)|psi-mi:YRA1(display_short)|uniprotkb:D9481.2(orf name)|uniprotkb:D9509.1(orf name)|uniprotkb:YDR381W(locus name) psi-mi:sub2_yeast(display_long)|uniprotkb:SUB2(gene name)|psi-mi:SUB2(display_short)|uniprotkb:Suppressor of BRR1 protein 2(gene name synonym)|uniprotkb:YDL084W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Johnson et al. (2011) pubmed:21947206|doi:10.1038/nsmb.2126|imex:IM-17085 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15945859|imex:IM-17085-3|dip:DIP-187995E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010669.1|sgd:S000002789|dip:DIP-1791N|mint:Q12159|ensemblfungi:YDR381W(gene)|ensemblfungi:YDR381W_mRNA(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:1902281"(negative regulation of RNA helicase activity)|go:"GO:1990119"(RNA helicase inhibitor activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034357|interpro:IPR035979|rcsb pdb:5SUP sgd:S000002242|refseq:NP_010199.1|ensemblfungi:YDL084W(gene)|rcsb pdb:5SUP|rcsb pdb:5SUQ|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006348"|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblfungi:YDL084W_mRNA(transcript)|dip:DIP-5343N|mint:Q07478 psi-mi:"MI:0465"(dip) crc64:480B5B6DC0D14BE9 crc64:AB3605A8C38A560C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:pLiU4X4uQRi7nw6fxaSJW7Ppum4559292 rogid:jIWYSXKwdexLISR24GhAf0aZvuU559292 rigid:+Ae2JfVLs2fnCXo18wY4z3WnRGw false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q08685 uniprotkb:P39081 intact:EBI-29732|uniprotkb:D6W2V1|ensemblfungi:YOR250C intact:EBI-12980|uniprotkb:Q04932|uniprotkb:D6VSL0|ensemblfungi:YDR228C psi-mi:clp1_yeast(display_long)|uniprotkb:CLP1(gene name)|psi-mi:CLP1(display_short)|uniprotkb:YOR250C(locus name) psi-mi:pcf11_yeast(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:YDR228C(locus name)|uniprotkb:YD9934.13C(orf name)|uniprotkb:protein 1 of CF I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Johnson et al. (2011) pubmed:21947206|doi:10.1038/nsmb.2126|imex:IM-17085 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15945840|imex:IM-17085-2|dip:DIP-1672E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014893.1|sgd:S000005776|dip:DIP-1487N|mint:Q08685|ensemblfungi:YOR250C(gene)|ensemblfungi:YOR250C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006396"(RNA processing)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR010655(Pre-mRNA cleavage complex II Clp1)|interpro:IPR027417|interpro:IPR028606|interpro:IPR032319|interpro:IPR032324|interpro:IPR038238|interpro:IPR038239|rcsb pdb:2NPI|rcsb pdb:4C0B|rcsb pdb:4C0H|rcsb pdb:4OI4 sgd:S000002636|ensemblfungi:YDR228C(gene)|ensemblfungi:YDR228C_mRNA(transcript)|refseq:NP_010514.3|go:"GO:0000993"(RNA polymerase II complex binding)|dip:DIP-944N|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|rcsb pdb:1SZ9|rcsb pdb:1SZA|rcsb pdb:2BF0|rcsb pdb:2NAX|rcsb pdb:2NPI|rcsb pdb:4C0B|rcsb pdb:4C0H|rcsb pdb:4OI4|rcsb pdb:5M9Z psi-mi:"MI:0465"(dip) crc64:B00F7659E83090DA crc64:66F91BA9577E82F1 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:WiC5KIjGJ6qTn+XuPdCL9J/eYeo559292 rogid:NT0NGp2ly1eBgnP0a3SbaAxU0ok559292 rigid:H/LbnMks0Zmajvv8dl33rWynUJ0 false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39081 uniprotkb:Q07478 intact:EBI-12980|uniprotkb:Q04932|uniprotkb:D6VSL0|ensemblfungi:YDR228C intact:EBI-18500|ensemblfungi:YDL084W|uniprotkb:D6VRR5 psi-mi:pcf11_yeast(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:YDR228C(locus name)|uniprotkb:YD9934.13C(orf name)|uniprotkb:protein 1 of CF I(gene name synonym) psi-mi:sub2_yeast(display_long)|uniprotkb:SUB2(gene name)|psi-mi:SUB2(display_short)|uniprotkb:Suppressor of BRR1 protein 2(gene name synonym)|uniprotkb:YDL084W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Johnson et al. (2011) pubmed:21947206|doi:10.1038/nsmb.2126|imex:IM-17085 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15945879|imex:IM-17085-4|dip:DIP-187996E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002636|ensemblfungi:YDR228C(gene)|ensemblfungi:YDR228C_mRNA(transcript)|refseq:NP_010514.3|go:"GO:0000993"(RNA polymerase II complex binding)|dip:DIP-944N|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|rcsb pdb:1SZ9|rcsb pdb:1SZA|rcsb pdb:2BF0|rcsb pdb:2NAX|rcsb pdb:2NPI|rcsb pdb:4C0B|rcsb pdb:4C0H|rcsb pdb:4OI4|rcsb pdb:5M9Z sgd:S000002242|refseq:NP_010199.1|ensemblfungi:YDL084W(gene)|rcsb pdb:5SUP|rcsb pdb:5SUQ|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006348"|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblfungi:YDL084W_mRNA(transcript)|dip:DIP-5343N|mint:Q07478 psi-mi:"MI:0465"(dip) crc64:66F91BA9577E82F1 crc64:AB3605A8C38A560C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:NT0NGp2ly1eBgnP0a3SbaAxU0ok559292 rogid:jIWYSXKwdexLISR24GhAf0aZvuU559292 rigid:HVr4FZyYruBJNLQwRe/8KzFuQYE false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)