#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10747-1	uniprotkb:P01552	intact:EBI-15945088|ensembl:ENSP00000324890	intact:EBI-1027464	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945145|imex:IM-15903-2|dip:DIP-186285E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO|refseq:WP_000278085.1|dip:DIP-35541N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	rigid:UAeJ3fc14riAdKC2A/RoUcg6Nos	false	binding-associated region:19-152|fc-igg tag:?-?	binding-associated region:28-266	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P0A0L2	uniprotkb:P10747-1	intact:EBI-15945094|uniprotkb:P13163	intact:EBI-15945088|ensembl:ENSP00000324890	psi-mi:etxa_staau(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:SEA(gene name synonym)	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945122|imex:IM-15903-1|dip:DIP-186286E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042289"(MHC class II protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1DYQ|rcsb pdb:1ESF|rcsb pdb:1I4G|rcsb pdb:1I4H|rcsb pdb:1LO5|rcsb pdb:1SEA|rcsb pdb:1SXT|rcsb pdb:5FK9|go:"GO:0005576"(extracellular region)|dip:DIP-58974N|refseq:WP_000750412.1	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:jhUIBoxnd8wrW5QYgylBF5cjRwU1280	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rigid:ZNt/whlmKiBaSadT1mpgE93Q1ag	false	binding-associated region:25-257	binding-associated region:26-33|binding-associated region:134-142	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10747-1	uniprotkb:P01552	intact:EBI-15945088|ensembl:ENSP00000324890	intact:EBI-1027464	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945215|imex:IM-15903-5|dip:DIP-186285E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO|refseq:WP_000278085.1|dip:DIP-35541N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	rigid:UAeJ3fc14riAdKC2A/RoUcg6Nos	false	binding-associated region:19-152	binding-associated region:28-266	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10747-1	uniprotkb:P01552	intact:EBI-15945088|ensembl:ENSP00000324890	intact:EBI-1027464	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945236|imex:IM-15903-6|dip:DIP-186285E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO|refseq:WP_000278085.1|dip:DIP-35541N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	rigid:UAeJ3fc14riAdKC2A/RoUcg6Nos	false	binding-associated region:26-33|binding-associated region:134-142	binding-associated region:28-266	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10747-1	uniprotkb:P01552	intact:EBI-15945088|ensembl:ENSP00000324890	intact:EBI-1027464	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945191|imex:IM-15903-4|dip:DIP-186285E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO|refseq:WP_000278085.1|dip:DIP-35541N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	rigid:UAeJ3fc14riAdKC2A/RoUcg6Nos	false	binding-associated region:19-152	binding-associated region:177-188|mutation decreasing interaction:179-179	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10747-1	uniprotkb:P01552	intact:EBI-15945088|ensembl:ENSP00000324890	intact:EBI-1027464	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945170|imex:IM-15903-3|dip:DIP-186285E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO|refseq:WP_000278085.1|dip:DIP-35541N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	rigid:UAeJ3fc14riAdKC2A/RoUcg6Nos	false	binding-associated region:19-152	binding-associated region:28-266	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42081-3	uniprotkb:P10747-1	intact:EBI-15945259|ensembl:ENSP00000377248	intact:EBI-15945088|ensembl:ENSP00000324890	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:p10747-1(display_long)|uniprotkb:CD28(gene name)|psi-mi:CD28(display_short)|uniprotkb:TP44(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Arad et al. (2011)	pubmed:21931534|doi:10.1371/journal.pbio.1001149|imex:IM-15903	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15945270|imex:IM-15903-7|dip:DIP-186287E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114013(gene)|ensembl:ENST00000393627(transcript)|intact:EBI-1030956(isoform-parent)	intact:EBI-4314301(isoform-parent)|ensembl:ENSG00000178562(gene)|ensembl:ENST00000324106(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:hXXImyYy1G/3xoStJWpisi3sIWI9606	rigid:b7R+HIo2yCapHHi3MDcbfDLNKeM	false	binding-associated region:20-239	binding-associated region:19-152	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)