#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5ZS31 uniprotkb:Q5ZRQ0 intact:EBI-15944034|ensemblbacteria:AAU28746 intact:EBI-6402540|ensemblbacteria:AAU28878 psi-mi:q5zs31_legph(display_long)|uniprotkb:icmW(gene name)|psi-mi:icmW(display_short)|uniprotkb:lpg2688(locus name) psi-mi:lubx_legph(display_long)|uniprotkb:Legionella U-box protein(gene name synonym)|uniprotkb:lubX(gene name)|psi-mi:lubX(display_short)|uniprotkb:legU2(gene name synonym)|uniprotkb:lpg2830(locus name)|uniprotkb:RING-type E3 ubiquitin transferase LubX(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944043|imex:IM-16181-1|dip:DIP-187171E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAU28746(transcript)|ensemblbacteria:lpg2688(gene)|rcsb pdb:5X1E|rcsb pdb:5X90|rcsb pdb:5XNB|rcsb pdb:7BWK|dip:DIP-59159N|refseq:WP_010948388.1|refseq:YP_096693.1 ensemblbacteria:AAU28878(transcript)|ensemblbacteria:lpg2830(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043657"(host cell)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_096825.1|dip:DIP-59158N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:8HAfcJcAvkjPhUFy1RCcFk340U4272624 rogid:0bi5TdwZ5OeOhOowhQlpuRL34p4272624 rigid:GXS3TbFdrh5v58ATE57DAm3Apxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QUK4 uniprotkb:Q2T728 intact:EBI-15944068|ensembl:ENSMUSP00000070827|ensembl:ENSMUSP00000113890|uniprotkb:A9C470|uniprotkb:O09124|uniprotkb:Q9R030 intact:EBI-15944060|ensemblbacteria:ABC35327 psi-mi:bir1b_mouse(display_long)|uniprotkb:Naip2(gene name)|psi-mi:Naip2(display_short)|uniprotkb:Birc1b(gene name synonym)|uniprotkb:Naip-rs6(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 2(gene name synonym) psi-mi:q2t728_burta(display_long)|uniprotkb:BTH_II0824(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:271848(burta)|taxid:271848("Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15944109|imex:IM-16181-2|dip:DIP-187181E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078945(gene)|ensembl:ENSMUST00000067975(transcript)|ensembl:ENSMUST00000117913(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0046872"(metal ion binding)|dip:DIP-59160N|refseq:NP_001119654.1|refseq:NP_035002.2 ensemblbacteria:ABC35327(transcript)|ensemblbacteria:BTH_II0824(gene)|dip:DIP-59152N|refseq:WP_009896108.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:ABA+SvqyqCEVHGRgvxA0iSaZpng10090 rogid:eziNUj00seLsZcepUMWoLkWlOk8271848 rigid:0BgCe5mFzY0iF+C7R/SNR7oa9oQ false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R016 uniprotkb:Q48824 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 intact:EBI-15944232 psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944246|imex:IM-16181-5|dip:DIP-187172E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2018/04/30 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:YNzrKWXWJisKCfnuop3zru6f/vc false - mutation disrupting interaction:473-473,472-472,470-470 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P72151 uniprotkb:Q9R016 intact:EBI-15944198|ensemblbacteria:AAG04481 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 psi-mi:flicb_pseae(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:PA1092(locus name) psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944215|imex:IM-16181-4|dip:DIP-187177E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|rcsb pdb:5WK5|rcsb pdb:5WK6|ensemblbacteria:AAG04481(transcript)|ensemblbacteria:PA1092(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|dip:DIP-59151N|refseq:NP_249783.1|refseq:WP_003112503.1 ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 psi-mi:"MI:0465"(dip) crc64:7A2AEE09D3F58209 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2018/04/30 rogid:dT1my/tsEJmZeRLaE94OV7FuLTc208964 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rigid:3g09f9MaPHVhO+NI+8bQAcFnnTg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7N5J4 uniprotkb:Q9R016 intact:EBI-15944167|ensemblbacteria:CAE14247 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 psi-mi:q7n5j4_pholl(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:plu1954(locus name) psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:243265(pholl)|taxid:243265("Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944181|imex:IM-16181-3|dip:DIP-187176E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CAE14247(transcript)|ensemblbacteria:plu1954(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR042187|dip:DIP-59157N|refseq:WP_011146216.1 ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2018/04/30 rogid:RYzBnjzsXmR9ox+RKii3boCRC6c243265 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rigid:BB172CtX3waoqZukmbi/h1m3Xhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7NVC1 uniprotkb:Q13075 intact:EBI-15944268|ensemblbacteria:AAQ60094 intact:EBI-2874875|ensembl:ENSP00000428657|ensembl:ENSP00000443944|ensembl:ENSP00000484107|ensembl:ENSP00000484731|uniprotkb:Q99796|uniprotkb:Q13730|uniprotkb:B9EG72|uniprotkb:Q59GI6|uniprotkb:O75857|uniprotkb:E9PHD1|uniprotkb:Q8TDZ4 psi-mi:q7nvc1_chrvo(display_long)|uniprotkb:prgI(gene name)|psi-mi:prgI(display_short)|uniprotkb:CV_2422(locus name) psi-mi:birc1_human(display_long)|uniprotkb:NAIP(gene name)|psi-mi:NAIP(display_short)|uniprotkb:BIRC1(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:243365(chrvo)|taxid:243365("Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15944278|imex:IM-16181-6|dip:DIP-187182E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030257"(type III protein secretion system complex)|ensemblbacteria:AAQ60094(transcript)|ensemblbacteria:CV_2422(gene)|go:"GO:0030254"(protein secretion by the type III secretion system)|interpro:IPR011841(Type III secretion system needle protein)|interpro:IPR021123|interpro:IPR037203 ensembl:ENSG00000249437(gene)|ensembl:ENSG00000278613(gene)|ensembl:ENST00000194097(transcript)|ensembl:ENST00000517649(transcript)|ensembl:ENST00000612328(transcript)|ensembl:ENST00000620988(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|interpro:IPR041075|mint:Q13075|rcsb pdb:2VM5|refseq:NP_004527.2|refseq:NP_075043.1|refseq:NP_001333799.1|dip:DIP-59150N psi-mi:"MI:0465"(dip) crc64:4730D6BEA9E7A0EF - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:CAC99K8fhwTvXWh2JfRegBJP9HE243365 rogid:ZgyidfeszAIZ7BCEFeUUxF7yOfk9606 rigid:+IZmu79G2Vz18gH7HNvHxf4UnsM false mutation disrupting interaction:79-79,69-69|flag tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9JIB6 uniprotkb:Q48824 intact:EBI-15944303|ensembl:ENSMUSP00000041766|ensembl:ENSMUSP00000112867|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81704|uniprotkb:Q8CH68 intact:EBI-15944232 psi-mi:bir1f_mouse(display_long)|uniprotkb:Naip6(gene name)|psi-mi:Naip6(display_short)|uniprotkb:Birc1f(gene name synonym)|uniprotkb:Naip-rs4(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 6(gene name synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944341|imex:IM-16181-7|dip:DIP-187173E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078942(gene)|ensembl:ENSMUST00000042220(transcript)|ensembl:ENSMUST00000118574(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|dip:DIP-59149N|refseq:NP_035001.2 go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:+eKDBpreLg6AApayzJ3cjQcdoEw10090 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:i8Brglo11+r91LCZgTiF7tg0fM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R016 uniprotkb:Q48824 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 intact:EBI-15944232 psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15944358|imex:IM-16181-8|dip:DIP-187172E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2018/04/30 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:YNzrKWXWJisKCfnuop3zru6f/vc false flag tag:n-n|ha tag:n-n mutation disrupting interaction:473-473,472-472,470-470|myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NPP4-1 uniprotkb:Q48824 intact:EBI-15944387|ensembl:ENSP00000354159|ensembl:ENSP00000385428 intact:EBI-15944232 psi-mi:q9npp4-1(display_long)|uniprotkb:NLRC4(gene name)|psi-mi:NLRC4(display_short)|uniprotkb:CARD12(gene name synonym)|uniprotkb:CLAN(gene name synonym)|uniprotkb:CLAN1(gene name synonym)|uniprotkb:IPAF(gene name synonym)|uniprotkb:CARD, LRR, and NACHT-containing protein(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)|uniprotkb:UNQ6189/PRO20215(orf name)|uniprotkb:CLANA(isoform synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15944403|imex:IM-16181-9|dip:DIP-187179E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1222527(isoform-parent)|ensembl:ENST00000360906(transcript)|ensembl:ENST00000402280(transcript)|ensembl:ENSG00000091106(gene) go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:9q8oK2jo8kCYn8rHEwkS8Y0g+9Y9606 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:H2kjKVdNLu+Acgyg3wtP10jMsdc false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P06179 uniprotkb:Q9R016 intact:EBI-2011501|uniprotkb:P97160|uniprotkb:Q02871|uniprotkb:Q56088|ensemblbacteria:AAL20871 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 psi-mi:flic_salty(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:flaF(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:Phase 1-I flagellin(gene name synonym)|uniprotkb:STM1959(locus name) psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944424|dip:DIP-187174E|imex:IM-16181-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_460912.1|refseq:WP_000079805.1|dip:DIP-43768N|mint:P06179|ensemblbacteria:AAL20871(transcript)|ensemblbacteria:STM1959(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR014981(Flagellin D3)|interpro:IPR042187|rcsb pdb:1IO1|rcsb pdb:1P95|rcsb pdb:1UCU|rcsb pdb:3A5X|rcsb pdb:5YUD|rcsb pdb:6CH3|reactome:R-GGA-433822|reactome:R-GGA-451534|reactome:R-GGA-977240|reactome:R-HSA-844623 ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 psi-mi:"MI:0465"(dip) crc64:4BD7849FA3B936BA - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2018/04/30 rogid:0JWcURU8Owt3IW+XBPx9sRk/Ou899287 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rigid:b0tH98Qxtu8dTe+dmsFDykWiZpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JIB6 uniprotkb:Q48824 intact:EBI-15944303|ensembl:ENSMUSP00000041766|ensembl:ENSMUSP00000112867|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81704|uniprotkb:Q8CH68 intact:EBI-15944232 psi-mi:bir1f_mouse(display_long)|uniprotkb:Naip6(gene name)|psi-mi:Naip6(display_short)|uniprotkb:Birc1f(gene name synonym)|uniprotkb:Naip-rs4(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 6(gene name synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15944441|imex:IM-16181-11|dip:DIP-187173E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078942(gene)|ensembl:ENSMUST00000042220(transcript)|ensembl:ENSMUST00000118574(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|dip:DIP-59149N|refseq:NP_035001.2 go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:+eKDBpreLg6AApayzJ3cjQcdoEw10090 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:i8Brglo11+r91LCZgTiF7tg0fM8 false flag tag:n-n|ha tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NPP4-1 uniprotkb:Q9JIB6 intact:EBI-15944387|ensembl:ENSP00000354159|ensembl:ENSP00000385428 intact:EBI-15944303|ensembl:ENSMUSP00000041766|ensembl:ENSMUSP00000112867|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81704|uniprotkb:Q8CH68 psi-mi:q9npp4-1(display_long)|uniprotkb:NLRC4(gene name)|psi-mi:NLRC4(display_short)|uniprotkb:CARD12(gene name synonym)|uniprotkb:CLAN(gene name synonym)|uniprotkb:CLAN1(gene name synonym)|uniprotkb:IPAF(gene name synonym)|uniprotkb:CARD, LRR, and NACHT-containing protein(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)|uniprotkb:UNQ6189/PRO20215(orf name)|uniprotkb:CLANA(isoform synonym) psi-mi:bir1f_mouse(display_long)|uniprotkb:Naip6(gene name)|psi-mi:Naip6(display_short)|uniprotkb:Birc1f(gene name synonym)|uniprotkb:Naip-rs4(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15944465|imex:IM-16181-12|dip:DIP-187180E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1222527(isoform-parent)|ensembl:ENST00000360906(transcript)|ensembl:ENST00000402280(transcript)|ensembl:ENSG00000091106(gene) ensembl:ENSMUSG00000078942(gene)|ensembl:ENSMUST00000042220(transcript)|ensembl:ENSMUST00000118574(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|dip:DIP-59149N|refseq:NP_035001.2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:9q8oK2jo8kCYn8rHEwkS8Y0g+9Y9606 rogid:+eKDBpreLg6AApayzJ3cjQcdoEw10090 rigid:2V3/EYnBCVECl3DYYmMqqXOvuOc false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NPP4-1 uniprotkb:Q48824 intact:EBI-15944387|ensembl:ENSP00000354159|ensembl:ENSP00000385428 intact:EBI-15944232 psi-mi:q9npp4-1(display_long)|uniprotkb:NLRC4(gene name)|psi-mi:NLRC4(display_short)|uniprotkb:CARD12(gene name synonym)|uniprotkb:CLAN(gene name synonym)|uniprotkb:CLAN1(gene name synonym)|uniprotkb:IPAF(gene name synonym)|uniprotkb:CARD, LRR, and NACHT-containing protein(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)|uniprotkb:UNQ6189/PRO20215(orf name)|uniprotkb:CLANA(isoform synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15944465|imex:IM-16181-12|dip:DIP-187180E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1222527(isoform-parent)|ensembl:ENST00000360906(transcript)|ensembl:ENST00000402280(transcript)|ensembl:ENSG00000091106(gene) go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:9q8oK2jo8kCYn8rHEwkS8Y0g+9Y9606 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:2V3/EYnBCVECl3DYYmMqqXOvuOc false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NPP4-1 uniprotkb:Q9R016 intact:EBI-15944387|ensembl:ENSP00000354159|ensembl:ENSP00000385428 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 psi-mi:q9npp4-1(display_long)|uniprotkb:NLRC4(gene name)|psi-mi:NLRC4(display_short)|uniprotkb:CARD12(gene name synonym)|uniprotkb:CLAN(gene name synonym)|uniprotkb:CLAN1(gene name synonym)|uniprotkb:IPAF(gene name synonym)|uniprotkb:CARD, LRR, and NACHT-containing protein(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)|uniprotkb:UNQ6189/PRO20215(orf name)|uniprotkb:CLANA(isoform synonym) psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15944538|imex:IM-16181-15|dip:DIP-187178E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1222527(isoform-parent)|ensembl:ENST00000360906(transcript)|ensembl:ENST00000402280(transcript)|ensembl:ENSG00000091106(gene) ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2018/04/30 rogid:9q8oK2jo8kCYn8rHEwkS8Y0g+9Y9606 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rigid:Na0PbVczbHMeeNQEnOQVf7ndPSw false necessary binding region:163-316|flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NPP4-1 uniprotkb:Q48824 intact:EBI-15944387|ensembl:ENSP00000354159|ensembl:ENSP00000385428 intact:EBI-15944232 psi-mi:q9npp4-1(display_long)|uniprotkb:NLRC4(gene name)|psi-mi:NLRC4(display_short)|uniprotkb:CARD12(gene name synonym)|uniprotkb:CLAN(gene name synonym)|uniprotkb:CLAN1(gene name synonym)|uniprotkb:IPAF(gene name synonym)|uniprotkb:CARD, LRR, and NACHT-containing protein(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 12(gene name synonym)|uniprotkb:Ice protease-activating factor(gene name synonym)|uniprotkb:UNQ6189/PRO20215(orf name)|uniprotkb:CLANA(isoform synonym) psi-mi:q48824_legpn(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:446(legpn)|taxid:446(Legionella pneumophila) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15944538|imex:IM-16181-15|dip:DIP-187178E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1222527(isoform-parent)|ensembl:ENST00000360906(transcript)|ensembl:ENST00000402280(transcript)|ensembl:ENSG00000091106(gene) go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR010810(Flagellin hook IN)|interpro:IPR042187|dip:DIP-59153N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2018/04/30 rogid:9q8oK2jo8kCYn8rHEwkS8Y0g+9Y9606 rogid:pgQKqS8JGDsgQVA0bkyOpu9+a7U446 rigid:Na0PbVczbHMeeNQEnOQVf7ndPSw false necessary binding region:163-316|flag tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A1JSQ1 uniprotkb:Q9R016 intact:EBI-15944506|ensemblbacteria:CAL12564 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 psi-mi:a1jsq1_yere8(display_long)|uniprotkb:fliC2(gene name)|psi-mi:fliC2(display_short)|uniprotkb:YE2521(locus name) psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:393305(yere8)|taxid:393305("Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944521|imex:IM-16181-14|dip:DIP-187175E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CAL12564(transcript)|ensemblbacteria:YE2521(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR042187|dip:DIP-59156N|refseq:WP_011816589.1|refseq:YP_001006728.1 ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2018/04/30 rogid:P5g8KCeV5iEZxJoLvHxAA6oVw/g393305 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rigid:BkCqjW2Leq6kGy7mKSNb4YzKIuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QUK4 uniprotkb:Q2T728 intact:EBI-15944068|ensembl:ENSMUSP00000070827|ensembl:ENSMUSP00000113890|uniprotkb:A9C470|uniprotkb:O09124|uniprotkb:Q9R030 intact:EBI-15944060|ensemblbacteria:ABC35327 psi-mi:bir1b_mouse(display_long)|uniprotkb:Naip2(gene name)|psi-mi:Naip2(display_short)|uniprotkb:Birc1b(gene name synonym)|uniprotkb:Naip-rs6(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 2(gene name synonym) psi-mi:q2t728_burta(display_long)|uniprotkb:BTH_II0824(locus name) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:271848(burta)|taxid:271848("Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944489|imex:IM-16181-13|dip:DIP-187181E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078945(gene)|ensembl:ENSMUST00000067975(transcript)|ensembl:ENSMUST00000117913(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070269"(pyroptosis)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|go:"GO:0046872"(metal ion binding)|dip:DIP-59160N|refseq:NP_001119654.1|refseq:NP_035002.2 ensemblbacteria:ABC35327(transcript)|ensemblbacteria:BTH_II0824(gene)|dip:DIP-59152N|refseq:WP_009896108.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ABA+SvqyqCEVHGRgvxA0iSaZpng10090 rogid:eziNUj00seLsZcepUMWoLkWlOk8271848 rigid:0BgCe5mFzY0iF+C7R/SNR7oa9oQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06179 uniprotkb:Q9R016 intact:EBI-2011501|uniprotkb:P97160|uniprotkb:Q02871|uniprotkb:Q56088|ensemblbacteria:AAL20871 intact:EBI-15944130|ensembl:ENSMUSP00000058611|uniprotkb:Q8CGT2|uniprotkb:O09121|uniprotkb:O09122|uniprotkb:P81703|uniprotkb:Q9R029 psi-mi:flic_salty(display_long)|uniprotkb:fliC(gene name)|psi-mi:fliC(display_short)|uniprotkb:flaF(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:Phase 1-I flagellin(gene name synonym)|uniprotkb:STM1959(locus name) psi-mi:bir1e_mouse(display_long)|uniprotkb:Naip5(gene name)|psi-mi:Naip5(display_short)|uniprotkb:Birc1e(gene name synonym)|uniprotkb:Naip-rs3(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (2011) pubmed:21918512|doi:10.1038/nature10510|imex:IM-16181 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15944565|dip:DIP-200467E|imex:IM-16181-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_460912.1|refseq:WP_000079805.1|dip:DIP-43768N|mint:P06179|ensemblbacteria:AAL20871(transcript)|ensemblbacteria:STM1959(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009288"(bacterial-type flagellum)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR014981(Flagellin D3)|interpro:IPR042187|rcsb pdb:1IO1|rcsb pdb:1P95|rcsb pdb:1UCU|rcsb pdb:3A5X|rcsb pdb:5YUD|rcsb pdb:6CH3|reactome:R-GGA-433822|reactome:R-GGA-451534|reactome:R-GGA-977240|reactome:R-HSA-844623 ensembl:ENSMUSG00000071203(gene)|ensembl:ENSMUST00000049789(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070269"(pyroptosis)|go:"GO:0072557"(IPAF inflammasome complex)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR041075|rcsb pdb:5YUD|rcsb pdb:6B5B|refseq:XP_011242930.1|refseq:XP_017170904.1|dip:DIP-59148N|refseq:NP_035000.2 psi-mi:"MI:0465"(dip) crc64:4BD7849FA3B936BA - dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2016-04-27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2018/04/30 rogid:0JWcURU8Owt3IW+XBPx9sRk/Ou899287 rogid:yNnApOdrkulKaMVJOTBVq+0lB3E10090 rigid:b0tH98Qxtu8dTe+dmsFDykWiZpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)