#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:B7UM99	uniprotkb:Q9UQB8-4	intact:EBI-2504426|ensemblbacteria:CAS11489|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943358|imex:IM-17473-1|dip:DIP-188703E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:CAS11489(transcript)|ensemblbacteria:E2348C_3941(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|mint:B7UM99	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:vC2WFh43BpYxnDfBS9+gY6csrRQ	false	binding-associated region:446-460|biotin tag:n-n	mutation disrupting interaction:196-196|binding-associated region:1-250|mutation disrupting interaction:108-108|green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7DB77	uniprotkb:Q9UQB8-4	intact:EBI-6480811|ensemblbacteria:AAG58825|ensemblbacteria:BAB37984|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943397|imex:IM-17473-2|dip:DIP-188702E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7DB77|ensemblbacteria:AAG58825(transcript)|ensemblbacteria:BAB37984(transcript)|ensemblbacteria:ECs_4561(gene)|ensemblbacteria:Z5112(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|refseq:WP_001301454.1|refseq:NP_312588.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR037003	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:VmXptIhA0VSa+F08VR8B0CxOkHk	false	binding-associated region:452-463	binding-associated region:1-250	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B7UM99	uniprotkb:Q9UQB8-4	intact:EBI-2504426|ensemblbacteria:CAS11489|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943418|imex:IM-17473-3|dip:DIP-188703E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:CAS11489(transcript)|ensemblbacteria:E2348C_3941(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|mint:B7UM99	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:vC2WFh43BpYxnDfBS9+gY6csrRQ	false	binding-associated region:448-459	binding-associated region:1-250	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7DB77	uniprotkb:Q9UQB8-4	intact:EBI-6480811|ensemblbacteria:AAG58825|ensemblbacteria:BAB37984|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943439|imex:IM-17473-4|dip:DIP-188702E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7DB77|ensemblbacteria:AAG58825(transcript)|ensemblbacteria:BAB37984(transcript)|ensemblbacteria:ECs_4561(gene)|ensemblbacteria:Z5112(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|refseq:WP_001301454.1|refseq:NP_312588.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR037003	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:VmXptIhA0VSa+F08VR8B0CxOkHk	false	binding-associated region:450-464|biotin tag:n-n	mutation disrupting interaction:196-196|binding-associated region:1-250|mutation disrupting interaction:108-108|green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7DB77	uniprotkb:Q9UQB8-4	intact:EBI-6480811|ensemblbacteria:AAG58825|ensemblbacteria:BAB37984|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943472|imex:IM-17473-5|dip:DIP-188702E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7DB77|ensemblbacteria:AAG58825(transcript)|ensemblbacteria:BAB37984(transcript)|ensemblbacteria:ECs_4561(gene)|ensemblbacteria:Z5112(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|refseq:WP_001301454.1|refseq:NP_312588.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR037003	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:VmXptIhA0VSa+F08VR8B0CxOkHk	false	binding-associated region:452-463|mutation disrupting interaction:458-458	binding-associated region:1-250	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B7UM99	uniprotkb:Q9UQB8-4	intact:EBI-2504426|ensemblbacteria:CAS11489|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943495|imex:IM-17473-6|dip:DIP-188703E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:CAS11489(transcript)|ensemblbacteria:E2348C_3941(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|mint:B7UM99	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:vC2WFh43BpYxnDfBS9+gY6csrRQ	false	binding-associated region:337-550|green fluorescent protein tag:n-n	mutation decreasing interaction:196-196|binding-associated region:1-250|mutation disrupting interaction:108-108|his tag:?-?|mutation disrupting interaction:28-28|mutation disrupting interaction:193-193|mutation disrupting interaction:193-193,108-108|mutation disrupting interaction:196-196,108-108	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7DB77	uniprotkb:Q9UQB8-4	intact:EBI-6480811|ensemblbacteria:AAG58825|ensemblbacteria:BAB37984|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943542|imex:IM-17473-7|dip:DIP-188702E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7DB77|ensemblbacteria:AAG58825(transcript)|ensemblbacteria:BAB37984(transcript)|ensemblbacteria:ECs_4561(gene)|ensemblbacteria:Z5112(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|refseq:WP_001301454.1|refseq:NP_312588.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR037003	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:VmXptIhA0VSa+F08VR8B0CxOkHk	false	binding-associated region:452-463	binding-associated region:1-250|mutation disrupting interaction:193-193|mutation disrupting interaction:108-108|mutation disrupting interaction:28-28|mutation decreasing interaction:196-196	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7DB77	uniprotkb:Q9UQB8-4	intact:EBI-6480811|ensemblbacteria:AAG58825|ensemblbacteria:BAB37984|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	de et al. (2011)	pubmed:21893288|doi:10.1016/j.str.2011.06.015|imex:IM-17473	taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15943575|imex:IM-17473-8|dip:DIP-188702E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7DB77|ensemblbacteria:AAG58825(transcript)|ensemblbacteria:BAB37984(transcript)|ensemblbacteria:ECs_4561(gene)|ensemblbacteria:Z5112(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|refseq:WP_001301454.1|refseq:NP_312588.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR037003	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rigid:VmXptIhA0VSa+F08VR8B0CxOkHk	false	binding-associated region:334-558|green fluorescent protein tag:n-n	mutation decreasing interaction:196-196|binding-associated region:1-250|mutation disrupting interaction:108-108|his tag:?-?|mutation disrupting interaction:28-28|mutation disrupting interaction:193-193|mutation disrupting interaction:193-193,108-108|mutation disrupting interaction:196-196,108-108	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)