#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-4399559	uniprotkb:P55854	dip:DIP-24261N	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940601|imex:IM-16129-2|dip:DIP-187062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rigid:eCSEatpvNN7OCwM8oHTqCKUimTo	false	mutation disrupting interaction:8-8|mutation disrupting interaction:44-44|mutation decreasing interaction:70-70	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62990	uniprotkb:P51668	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940627|imex:IM-16129-3|dip:DIP-187058E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:KNvIhLsUUpyKg4cZSKTbjSu9/As	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:O88846	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940645|imex:IM-16129-4|dip:DIP-187055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rigid:EMRtm8IXPPp02fCd/WOIHy7eKq4	false	binding-associated region:134-194	binding-associated region:134-194	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:O88846	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940583|imex:IM-16129-1|dip:DIP-187055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rigid:EMRtm8IXPPp02fCd/WOIHy7eKq4	false	binding-associated region:134-194	binding-associated region:134-194	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62990	uniprotkb:P51668	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940772|imex:IM-16129-9|dip:DIP-187058E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:KNvIhLsUUpyKg4cZSKTbjSu9/As	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:P55854	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940789|imex:IM-16129-10|dip:DIP-187056E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rigid:YbFd1vLhkeT3SW+CH2Sc1bRJRAg	false	sufficient binding region:32-76|maltose binding protein tag:n-n|mutation disrupting interaction:74-74,73-73,72-72,71-71,63-63,62-62,61-61,53-53,51-51,50-50,43-43,42-42,40-40	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O88846	uniprotkb:P51668	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940736|imex:IM-16129-8|dip:DIP-187060E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:AkpssFcHa5pgoXtWVy4ojQUm6sc	false	maltose binding protein tag:n-n|sufficient binding region:134-194|mutation disrupting interaction:181-181,140-140|mutation disrupting interaction:192-192|mutation disrupting interaction:194-194|mutation disrupting interaction strength:193-193|mutation disrupting interaction strength:193-193	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O88846	uniprotkb:P62990	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940736|imex:IM-16129-8|dip:DIP-187060E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:AkpssFcHa5pgoXtWVy4ojQUm6sc	false	maltose binding protein tag:n-n|sufficient binding region:134-194|mutation disrupting interaction:181-181,140-140|mutation disrupting interaction:192-192|mutation disrupting interaction:194-194|mutation disrupting interaction strength:193-193|mutation disrupting interaction strength:193-193	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O88846	uniprotkb:P51668	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0998"(deubiquitinase assay)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0204"(deubiquitination reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940719|imex:IM-16129-7|dip:DIP-187059E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:T3U2s3ITDphxtoYjGwoykEQrjoc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-4399559	uniprotkb:P51668	dip:DIP-24261N	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940825|imex:IM-16129-11|dip:DIP-187061E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:8vzk5uqTaWlpyQoqtBdsrp9lqUo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	intact:EBI-4399559	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	dip:DIP-24261N	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940663|imex:IM-16129-5|dip:DIP-187063E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:gLJ6TMAVqoLiuhYWlTpT96RshNc	false	maltose binding protein tag:n-n	mutation disrupting interaction:44-44	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:P51668	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940663|imex:IM-16129-5|dip:DIP-187063E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:gLJ6TMAVqoLiuhYWlTpT96RshNc	false	maltose binding protein tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:O88846	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940686|imex:IM-16129-6|dip:DIP-187055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rigid:EMRtm8IXPPp02fCd/WOIHy7eKq4	false	mutation disrupting interaction:191-194|mutation disrupting interaction:138-138|mutation disrupting interaction:190-190|mutation disrupting interaction:192-192|mutation disrupting interaction:193-193|mutation disrupting interaction:194-194	mutation disrupting interaction:191-194|mutation disrupting interaction:138-138|mutation disrupting interaction:190-190|mutation disrupting interaction:192-192|mutation disrupting interaction:193-193|mutation disrupting interaction:194-194	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:O88846	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940878|imex:IM-16129-14|dip:DIP-187055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rigid:q5VFNnaPfyh4TrPXWxgBcNfdkEw	false	binding-associated region:134-194|yellow fluorescent protein tag:n-n|mutation disrupting interaction:194-194|mutation decreasing interaction:181-181,140-140	binding-associated region:134-194|cyan fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88846	uniprotkb:P51668	intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940859|imex:IM-16129-13|dip:DIP-187059E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	psi-mi:"MI:0465"(dip)	comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:T3U2s3ITDphxtoYjGwoykEQrjoc	false	maltose binding protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P62990	uniprotkb:P55854	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940842|imex:IM-16129-12|dip:DIP-187057E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rigid:JGHMaTu5Ozq2nLiiWfcoI4BLYVA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62990	uniprotkb:P55854	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Plechanovová et al. (2011)	pubmed:21857666|doi:10.1038/nsmb.2108|imex:IM-16129	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15940910|imex:IM-16129-15|dip:DIP-187057E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rigid:JGHMaTu5Ozq2nLiiWfcoI4BLYVA	false	125i radiolabel:?-?	his tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)