#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WJB7 uniprotkb:P9WJB7 intact:EBI-15937970|uniprotkb:L0TDR1|uniprotkb:P96228|uniprotkb:Q8VIS2 intact:EBI-15937970|uniprotkb:L0TDR1|uniprotkb:P96228|uniprotkb:Q8VIS2 psi-mi:espr_myctu(display_long)|uniprotkb:espR(gene name)|psi-mi:espR(display_short)|uniprotkb:ESX-1 transcriptional regulatory protein EspR(gene name synonym)|uniprotkb:Rv3849(locus name) psi-mi:espr_myctu(display_long)|uniprotkb:espR(gene name)|psi-mi:espR(display_short)|uniprotkb:ESX-1 transcriptional regulatory protein EspR(gene name synonym)|uniprotkb:Rv3849(locus name) psi-mi:"MI:0071"(molecular sieving) Rosenberg et al. (2011) pubmed:21795602|doi:10.1073/pnas.1110242108|imex:IM-17741 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15938000|imex:IM-17741-1|dip:DIP-189147E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009295"(nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0052572"(response to host immune response)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001387(Helix-turn-helix type 3)|rcsb pdb:3QF3|rcsb pdb:3QWG|rcsb pdb:3QYX|rcsb pdb:3R1F|rcsb pdb:4NDW|refseq:NP_218366.1|refseq:WP_003399759.1 go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009295"(nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0052572"(response to host immune response)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001387(Helix-turn-helix type 3)|rcsb pdb:3QF3|rcsb pdb:3QWG|rcsb pdb:3QYX|rcsb pdb:3R1F|rcsb pdb:4NDW|refseq:NP_218366.1|refseq:WP_003399759.1 psi-mi:"MI:0465"(dip) crc64:84EA0DB906D81996 crc64:84EA0DB906D81996 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pu4mEVBeRf+arzdadjACkW6MUgw83332 rogid:pu4mEVBeRf+arzdadjACkW6MUgw83332 rigid:VPP6foD5kJ/II67FqS10So5nKJU false necessary binding region:108-132 necessary binding region:108-132 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WJB7 uniprotkb:P9WJB7 intact:EBI-15937970|uniprotkb:L0TDR1|uniprotkb:P96228|uniprotkb:Q8VIS2 intact:EBI-15937970|uniprotkb:L0TDR1|uniprotkb:P96228|uniprotkb:Q8VIS2 psi-mi:espr_myctu(display_long)|uniprotkb:espR(gene name)|psi-mi:espR(display_short)|uniprotkb:ESX-1 transcriptional regulatory protein EspR(gene name synonym)|uniprotkb:Rv3849(locus name) psi-mi:espr_myctu(display_long)|uniprotkb:espR(gene name)|psi-mi:espR(display_short)|uniprotkb:ESX-1 transcriptional regulatory protein EspR(gene name synonym)|uniprotkb:Rv3849(locus name) psi-mi:"MI:0114"(x-ray crystallography) Rosenberg et al. (2011) pubmed:21795602|doi:10.1073/pnas.1110242108|imex:IM-17741 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15938019|imex:IM-17741-2|dip:DIP-189147E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009295"(nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0052572"(response to host immune response)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001387(Helix-turn-helix type 3)|rcsb pdb:3QF3|rcsb pdb:3QWG|rcsb pdb:3QYX|rcsb pdb:3R1F|rcsb pdb:4NDW|refseq:NP_218366.1|refseq:WP_003399759.1 go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009295"(nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0052572"(response to host immune response)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001387(Helix-turn-helix type 3)|rcsb pdb:3QF3|rcsb pdb:3QWG|rcsb pdb:3QYX|rcsb pdb:3R1F|rcsb pdb:4NDW|refseq:NP_218366.1|refseq:WP_003399759.1 psi-mi:"MI:0465"(dip) crc64:84EA0DB906D81996 crc64:84EA0DB906D81996 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pu4mEVBeRf+arzdadjACkW6MUgw83332 rogid:pu4mEVBeRf+arzdadjACkW6MUgw83332 rigid:VPP6foD5kJ/II67FqS10So5nKJU false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WJB7 uniprotkb:P9WJB7 intact:EBI-15937970|uniprotkb:L0TDR1|uniprotkb:P96228|uniprotkb:Q8VIS2 intact:EBI-15937970|uniprotkb:L0TDR1|uniprotkb:P96228|uniprotkb:Q8VIS2 psi-mi:espr_myctu(display_long)|uniprotkb:espR(gene name)|psi-mi:espR(display_short)|uniprotkb:ESX-1 transcriptional regulatory protein EspR(gene name synonym)|uniprotkb:Rv3849(locus name) psi-mi:espr_myctu(display_long)|uniprotkb:espR(gene name)|psi-mi:espR(display_short)|uniprotkb:ESX-1 transcriptional regulatory protein EspR(gene name synonym)|uniprotkb:Rv3849(locus name) psi-mi:"MI:0104"(static light scattering) Rosenberg et al. (2011) pubmed:21795602|doi:10.1073/pnas.1110242108|imex:IM-17741 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15938035|imex:IM-17741-3|dip:DIP-189147E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009295"(nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0052572"(response to host immune response)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001387(Helix-turn-helix type 3)|rcsb pdb:3QF3|rcsb pdb:3QWG|rcsb pdb:3QYX|rcsb pdb:3R1F|rcsb pdb:4NDW|refseq:NP_218366.1|refseq:WP_003399759.1 go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009295"(nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0052572"(response to host immune response)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001387(Helix-turn-helix type 3)|rcsb pdb:3QF3|rcsb pdb:3QWG|rcsb pdb:3QYX|rcsb pdb:3R1F|rcsb pdb:4NDW|refseq:NP_218366.1|refseq:WP_003399759.1 psi-mi:"MI:0465"(dip) crc64:84EA0DB906D81996 crc64:84EA0DB906D81996 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:pu4mEVBeRf+arzdadjACkW6MUgw83332 rogid:pu4mEVBeRf+arzdadjACkW6MUgw83332 rigid:VPP6foD5kJ/II67FqS10So5nKJU false necessary binding region:108-132 necessary binding region:108-132 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)