#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32569 uniprotkb:P32570 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15933975|imex:IM-17479-2|dip:DIP-186336E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:7703E4FAE101A31F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 rigid:z5oYndEyioXjHoZMXA8Sk80xO+o false his tag:n-n|binding-associated region:303-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:Q99278 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-27213|uniprotkb:D6VZT5 psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15933975|imex:IM-17479-2|dip:DIP-186336E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:457D13C6030F33CC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rigid:z5oYndEyioXjHoZMXA8Sk80xO+o false his tag:n-n|binding-associated region:303-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q99278 uniprotkb:P32569 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15933951|imex:IM-17479-1|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:D25B2993A1BADFD6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - binding-associated region:109-687 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P32585 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15933951|imex:IM-17479-1|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:B1148FC187C2802A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P34162 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15933951|imex:IM-17479-1|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:C30BF309D43AFB2A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P32570 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15933951|imex:IM-17479-1|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:7703E4FAE101A31F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P38782 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07 psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:"MI:0114"(x-ray crystallography) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15933951|imex:IM-17479-1|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:B84E87DCC2737849 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P38304 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15933951|imex:IM-17479-1|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:86B2A064293C6B61 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32569 uniprotkb:P34162 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15934019|imex:IM-17479-4|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162 psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:C30BF309D43AFB2A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false his tag:n-n|sufficient binding region:1-400|sufficient binding region:201-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P32585 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15934019|imex:IM-17479-4|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:B1148FC187C2802A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false his tag:n-n|sufficient binding region:1-400|sufficient binding region:201-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P32570 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15934019|imex:IM-17479-4|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:7703E4FAE101A31F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false his tag:n-n|sufficient binding region:1-400|sufficient binding region:201-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:Q99278 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-27213|uniprotkb:D6VZT5 psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15934019|imex:IM-17479-4|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:457D13C6030F33CC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false his tag:n-n|sufficient binding region:1-400|sufficient binding region:201-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P38304 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15934019|imex:IM-17479-4|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:86B2A064293C6B61 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false his tag:n-n|sufficient binding region:1-400|sufficient binding region:201-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P38782 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07 psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15934019|imex:IM-17479-4|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:B84E87DCC2737849 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false his tag:n-n|sufficient binding region:1-400|sufficient binding region:201-687 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P32570 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15933997|imex:IM-17479-3|dip:DIP-186335E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:7703E4FAE101A31F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 rigid:x6DLtSo+5xou06ucSV213zQBgGw false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:Q99278 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-27213|uniprotkb:D6VZT5 psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15933997|imex:IM-17479-3|dip:DIP-186335E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:457D13C6030F33CC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rigid:x6DLtSo+5xou06ucSV213zQBgGw false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P38304 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15933997|imex:IM-17479-3|dip:DIP-186335E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:86B2A064293C6B61 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rigid:x6DLtSo+5xou06ucSV213zQBgGw false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P32569 uniprotkb:P38782 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07 psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:"MI:0096"(pull down) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15933997|imex:IM-17479-3|dip:DIP-186335E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N psi-mi:"MI:0465"(dip) crc64:D25B2993A1BADFD6 crc64:B84E87DCC2737849 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292 rigid:x6DLtSo+5xou06ucSV213zQBgGw false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q99278 uniprotkb:P32569 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15934047|imex:IM-17479-5|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:D25B2993A1BADFD6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - sufficient binding region:1-400 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P32585 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15934047|imex:IM-17479-5|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:B1148FC187C2802A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P34162 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15934047|imex:IM-17479-5|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:C30BF309D43AFB2A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P32570 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15934047|imex:IM-17479-5|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:7703E4FAE101A31F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P38782 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07 psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15934047|imex:IM-17479-5|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:B84E87DCC2737849 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P38304 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Imasaki et al. (2011) pubmed:21725323|doi:10.1038/nature10162|imex:IM-17479 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15934047|imex:IM-17479-5|dip:DIP-186334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N psi-mi:"MI:0465"(dip) crc64:457D13C6030F33CC crc64:86B2A064293C6B61 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/07 2017/08/10 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rigid:GfnHUYriwLbV8enkqbNKsjWSJZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)