#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O44514 uniprotkb:Q10038 intact:EBI-15932353|ensemblmetazoa:F42G8.4a.1|ensemblmetazoa:F42G8.4a.2 intact:EBI-15932305|ensemblmetazoa:F08B1.1a.1|ensemblmetazoa:F08B1.1a.2|ensemblmetazoa:F08B1.1a.3|uniprotkb:Q8IG35|uniprotkb:Q8ST18|uniprotkb:Q8ST19 psi-mi:pmk3_caeel(display_long)|uniprotkb:pmk-3(gene name)|psi-mi:pmk-3(display_short)|uniprotkb:Stress-activated protein kinase pmk-3(gene name synonym)|uniprotkb:p38 MAP kinase 3(gene name synonym)|uniprotkb:F42G8.4(orf name) psi-mi:vhp1_caeel(display_long)|uniprotkb:vhp-1(gene name)|psi-mi:vhp-1(display_short)|uniprotkb:Vh1 dual specificity phosphatase family protein 1(gene name synonym)|uniprotkb:F08B1.1(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nix et al. (2011) pubmed:21670305|doi:10.1073/pnas.1104830108|imex:IM-17683 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15932388|imex:IM-17683-1|dip:DIP-189024E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905868"(regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblmetazoa:F42G8.4a.1(transcript)|ensemblmetazoa:F42G8.4a.2(transcript)|ensemblmetazoa:WBGene00004057(gene)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|refseq:NP_501363.1|wormbase:F42G8.4a|dip:DIP-59691N go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008579"(JUN kinase phosphatase activity)|go:"GO:0017017"(MAP kinase tyrosine/serine/threonine phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR008343(MAP kinase phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR036873|ensemblmetazoa:F08B1.1a.1(transcript)|ensemblmetazoa:F08B1.1a.2(transcript)|ensemblmetazoa:F08B1.1a.3(transcript)|ensemblmetazoa:WBGene00006923(gene)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008330"(protein tyrosine/threonine phosphatase activity)|reactome:R-CEL-112409|reactome:R-CEL-5675221|refseq:NP_494997.1|refseq:NP_494998.1|refseq:NP_871926.1|wormbase:F08B1.1a|wormbase:F08B1.1b|dip:DIP-59690N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:MfrQjQA0mpqSellxlUsklUUBqyo6239 rogid:C8FrKl7Q+Ngozg4s5CswycRl5ns6239 rigid:Z+fBtKQs5U5dn+Qv0smc572VetE false ha tag:n-n t7 tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)