#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q80UE6	uniprotkb:Q13507-3	intact:EBI-295378|uniprotkb:Q4VAC1|uniprotkb:Q80XB5|uniprotkb:Q80XN2|uniprotkb:Q8R0N0|uniprotkb:Q8R340|uniprotkb:A2A4J7|ensembl:ENSMUSP00000099397	intact:EBI-15563545|ensembl:ENSP00000264811	psi-mi:wnk4_mouse(display_long)|uniprotkb:Wnk4(gene name)|psi-mi:Wnk4(display_short)|uniprotkb:Prkwnk4(gene name synonym)|uniprotkb:Protein kinase with no lysine 4(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 4(gene name synonym)	psi-mi:q13507-3(display_long)|uniprotkb:TRPC3(gene name)|psi-mi:TRPC3(display_short)|uniprotkb:TRP3(gene name synonym)|uniprotkb:Transient receptor protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2011)	pubmed:21670282|doi:10.1073/pnas.1104271108|imex:IM-17682	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15932042|imex:IM-17682-1|dip:DIP-189022E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_783569.1|dip:DIP-33231N|ensembl:ENSMUSG00000035112(gene)|ensembl:ENSMUST00000103108(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0008104"(protein localization)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|mint:Q80UE6|reactome:R-MMU-2672351	intact:EBI-520807(isoform-parent)|ensembl:ENSG00000138741(gene)|ensembl:ENST00000264811(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:Djz8WcXVZvZ4fNqMjyR9lPdOL2A10090	rogid:BcyEi+A3B2pbAtnL+TeRQ76leMc9606	rigid:yUMtMLch9udExbb58IEQvA66gQU	false	myc tag:n-n	sufficient binding region:1-196|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9JMI9	uniprotkb:Q7TPK6	intact:EBI-15932106	intact:EBI-15932067|ensembl:ENSRNOP00000027770|uniprotkb:Q810H4|uniprotkb:Q811R5	psi-mi:trpc3_rat(display_long)|uniprotkb:Trpc3(gene name)|psi-mi:Trpc3(display_short)|uniprotkb:Trrp3(gene name synonym)|uniprotkb:Trp-related protein 3(gene name synonym)	psi-mi:wnk4_rat(display_long)|uniprotkb:Wnk4(gene name)|psi-mi:Wnk4(display_short)|uniprotkb:Prkwnk4(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 4(gene name synonym)|uniprotkb:Protein kinase with no lysine 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Park et al. (2011)	pubmed:21670282|doi:10.1073/pnas.1104271108|imex:IM-17682	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15932128|imex:IM-17682-2|dip:DIP-189023E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007338"(single fertilization)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0033198"(response to ATP)|go:"GO:0034703"(cation channel complex)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005459(Transient receptor potential channel 3)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770|reactome:R-RNO-114508|reactome:R-RNO-139853|reactome:R-RNO-3295583|dip:DIP-59688N|rgd:61973	ensembl:ENSRNOG00000020441(gene)|ensembl:ENSRNOT00000027770(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0008104"(protein localization)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|reactome:R-RNO-2672351|refseq:NP_783169.2|dip:DIP-59689N|rgd:631401	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	-	2017/08/07	2017/08/10	rogid:Cj7rnIJawiFqprDisxhiF3jQWJU10116	rogid:gDs6E+NvcOvfKuOnb1ZAHDBrozY10116	rigid:qPLCHiqK7GT4+V+SMLfePydvPIM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q80UE6	uniprotkb:Q13507-3	intact:EBI-295378|uniprotkb:Q4VAC1|uniprotkb:Q80XB5|uniprotkb:Q80XN2|uniprotkb:Q8R0N0|uniprotkb:Q8R340|uniprotkb:A2A4J7|ensembl:ENSMUSP00000099397	intact:EBI-15563545|ensembl:ENSP00000264811	psi-mi:wnk4_mouse(display_long)|uniprotkb:Wnk4(gene name)|psi-mi:Wnk4(display_short)|uniprotkb:Prkwnk4(gene name synonym)|uniprotkb:Protein kinase with no lysine 4(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 4(gene name synonym)	psi-mi:q13507-3(display_long)|uniprotkb:TRPC3(gene name)|psi-mi:TRPC3(display_short)|uniprotkb:TRP3(gene name synonym)|uniprotkb:Transient receptor protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2011)	pubmed:21670282|doi:10.1073/pnas.1104271108|imex:IM-17682	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15932145|imex:IM-17682-3|dip:DIP-189022E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_783569.1|dip:DIP-33231N|ensembl:ENSMUSG00000035112(gene)|ensembl:ENSMUST00000103108(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0008104"(protein localization)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|mint:Q80UE6|reactome:R-MMU-2672351	intact:EBI-520807(isoform-parent)|ensembl:ENSG00000138741(gene)|ensembl:ENST00000264811(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:Djz8WcXVZvZ4fNqMjyR9lPdOL2A10090	rogid:BcyEi+A3B2pbAtnL+TeRQ76leMc9606	rigid:yUMtMLch9udExbb58IEQvA66gQU	false	myc tag:n-n|sufficient binding region:441-799	ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)