#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32769 uniprotkb:P33309 intact:EBI-8194|uniprotkb:D6VXE4|ensemblfungi:YKR084C intact:EBI-6012|uniprotkb:D6W1H6|ensemblfungi:YNL001W psi-mi:hbs1_yeast(display_long)|uniprotkb:HBS1(gene name)|psi-mi:HBS1(display_short)|uniprotkb:YKR404(orf name)|uniprotkb:YKR084C(locus name) psi-mi:dom34_yeast(display_long)|uniprotkb:N2016(orf name)|uniprotkb:YNL001W(locus name)|uniprotkb:DOM34(gene name)|psi-mi:DOM34(display_short) psi-mi:"MI:0410"(3D electron microscopy) Becker et al. (2011) pubmed:21623367|doi:10.1038/nsmb.2057|imex:IM-16104 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928901|imex:IM-16104-1|dip:DIP-89878E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001792|refseq:NP_013010.3|dip:DIP-762N|ensemblfungi:YKR084C(gene)|ensemblfungi:YKR084C_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:3IZQ|rcsb pdb:3P26|rcsb pdb:3P27|rcsb pdb:5M1J|reactome:R-SCE-429958 refseq:NP_014397.1|sgd:S000004946|dip:DIP-7520N|ensemblfungi:YNL001W(gene)|ensemblfungi:YNL001W_mRNA(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|rcsb pdb:2VGM|rcsb pdb:2VGN|rcsb pdb:3IZQ|rcsb pdb:3J16|rcsb pdb:5M1J psi-mi:"MI:0465"(dip) crc64:11EC2CB6936396EE crc64:4E8B7D9BBCD60888 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:8WhkbGcgKAw41+dB1sOeeew1RJY559292 rogid:AjrNfKo6LoskZXKNyN+4qXBZEUQ559292 rigid:uGtcFGquKxfKlJAHkr1b05v0MeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32769 uniprotkb:P33309 intact:EBI-8194|uniprotkb:D6VXE4|ensemblfungi:YKR084C intact:EBI-6012|uniprotkb:D6W1H6|ensemblfungi:YNL001W psi-mi:hbs1_yeast(display_long)|uniprotkb:HBS1(gene name)|psi-mi:HBS1(display_short)|uniprotkb:YKR404(orf name)|uniprotkb:YKR084C(locus name) psi-mi:dom34_yeast(display_long)|uniprotkb:N2016(orf name)|uniprotkb:YNL001W(locus name)|uniprotkb:DOM34(gene name)|psi-mi:DOM34(display_short) psi-mi:"MI:0071"(molecular sieving) Becker et al. (2011) pubmed:21623367|doi:10.1038/nsmb.2057|imex:IM-16104 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928918|imex:IM-16104-2|dip:DIP-89878E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001792|refseq:NP_013010.3|dip:DIP-762N|ensemblfungi:YKR084C(gene)|ensemblfungi:YKR084C_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:3IZQ|rcsb pdb:3P26|rcsb pdb:3P27|rcsb pdb:5M1J|reactome:R-SCE-429958 refseq:NP_014397.1|sgd:S000004946|dip:DIP-7520N|ensemblfungi:YNL001W(gene)|ensemblfungi:YNL001W_mRNA(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|rcsb pdb:2VGM|rcsb pdb:2VGN|rcsb pdb:3IZQ|rcsb pdb:3J16|rcsb pdb:5M1J psi-mi:"MI:0465"(dip) crc64:11EC2CB6936396EE crc64:4E8B7D9BBCD60888 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:8WhkbGcgKAw41+dB1sOeeew1RJY559292 rogid:AjrNfKo6LoskZXKNyN+4qXBZEUQ559292 rigid:uGtcFGquKxfKlJAHkr1b05v0MeE false sufficient binding region:153-611 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)