#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q62765-1 uniprotkb:Q28146-1 intact:EBI-8616448|intact:MINT-1527015|ensembl:ENSRNOP00000075793 intact:EBI-15928725 psi-mi:q62765-1(display_long)|uniprotkb:Nlgn1(gene name)|psi-mi:Nlgn1(display_short)|uniprotkb:Neuroligin I(gene name synonym) psi-mi:q28146-1(display_long)|uniprotkb:NRXN1(gene name)|psi-mi:NRXN1(display_short)|uniprotkb:Neurexin I-alpha(gene name synonym)|uniprotkb:Neurexin-1-alpha(gene name synonym)|uniprotkb:Alpha-1A2A3A4A5A(isoform synonym) psi-mi:"MI:0107"(surface plasmon resonance) Miller et al. (2011) pubmed:21620717|doi:10.1016/j.str.2011.03.011|imex:IM-16160 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928734|imex:IM-16160-1|dip:DIP-187151E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7281118(nlgn1_rat)|ensembl:ENSRNOG00000032576(gene)|ensembl:ENSRNOT00000092660(transcript) intact:EBI-16355788(isoform-parent) psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:I6UajYCOkz8f+3nt2IHH2rOCby810116 rogid:hnqA/uArQJEBmJPHrn0ioAEowEs9913 rigid:hIP51rCkJYsyQTPnIh9O/z43mC0 false binding-associated region:46-693 sufficient binding region:927-1349 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62765-1 uniprotkb:Q63373 intact:EBI-8616448|intact:MINT-1527015|ensembl:ENSRNOP00000075793 intact:EBI-1780696 psi-mi:q62765-1(display_long)|uniprotkb:Nlgn1(gene name)|psi-mi:Nlgn1(display_short)|uniprotkb:Neuroligin I(gene name synonym) psi-mi:nrx1b_rat(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-beta(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Miller et al. (2011) pubmed:21620717|doi:10.1016/j.str.2011.03.011|imex:IM-16160 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928755|imex:IM-16160-2|dip:DIP-187152E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7281118(nlgn1_rat)|ensembl:ENSRNOG00000032576(gene)|ensembl:ENSRNOT00000092660(transcript) rgd:628659|dip:DIP-40508N|go:"GO:0001525"(angiogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009986"(cell surface)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042297"(vocal learning)|go:"GO:0042551"(neuron maturation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090126"(protein-containing complex assembly involved in synapse maturation)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905520"(positive regulation of presynaptic active zone assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789|rcsb pdb:1C4R|rcsb pdb:2R1B|rcsb pdb:2R1D|rcsb pdb:2WQZ|rcsb pdb:2XB6 psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:I6UajYCOkz8f+3nt2IHH2rOCby810116 rogid:pd7OfT32rDvttEtlEt1ZEdtxPlI10116 rigid:358J8w9IBzUH+efWB6DVyx/rGMY false binding-associated region:46-693 binding-associated region:81-288 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)