#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36012 uniprotkb:P02309 intact:EBI-5182|uniprotkb:D6VXN8|ensemblfungi:YKL049C intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W psi-mi:cenpa_yeast(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CSL2(gene name synonym)|uniprotkb:YKL262(orf name)|uniprotkb:YKL049C(locus name) psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928297|imex:IM-21304-2|dip:DIP-191285E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012875.2|sgd:S000001532|dip:DIP-8048N|ensemblfungi:YKL049C(gene)|ensemblfungi:YKL049C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030543"(2-micrometer plasmid partitioning)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2FSB|rcsb pdb:2FSC|rcsb pdb:2L5A|rcsb pdb:2LY8|rcsb pdb:6UPH|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214841|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-9018519 refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) crc64:0170A10060EEC309 crc64:69B7D1F89E62DE41 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:TR0UUGVelC2Gg5qjnGp3HSCrxbA559292 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 rigid:1FsmFuY/NiNbzkTHdP5kqynoDn0 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P36012 uniprotkb:Q12334 intact:EBI-5182|uniprotkb:D6VXN8|ensemblfungi:YKL049C intact:EBI-31788|uniprotkb:D6VRK9|ensemblfungi:YDL139C psi-mi:cenpa_yeast(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CSL2(gene name synonym)|uniprotkb:YKL262(orf name)|uniprotkb:YKL049C(locus name) psi-mi:scm3_yeast(display_long)|uniprotkb:Suppressor of chromosome missegregation protein 3(gene name synonym)|uniprotkb:SCM3(gene name)|psi-mi:SCM3(display_short)|uniprotkb:YDL139C(locus name)|uniprotkb:D2155(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928297|imex:IM-21304-2|dip:DIP-191285E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012875.2|sgd:S000001532|dip:DIP-8048N|ensemblfungi:YKL049C(gene)|ensemblfungi:YKL049C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030543"(2-micrometer plasmid partitioning)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2FSB|rcsb pdb:2FSC|rcsb pdb:2L5A|rcsb pdb:2LY8|rcsb pdb:6UPH|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214841|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-9018519 refseq:NP_010142.2|sgd:S000002298|dip:DIP-5045N|mint:Q12334|ensemblfungi:YDL139C(gene)|ensemblfungi:YDL139C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2L5A psi-mi:"MI:0465"(dip) crc64:0170A10060EEC309 crc64:D7668117BCC7FF12 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:TR0UUGVelC2Gg5qjnGp3HSCrxbA559292 rogid:XeI5kq0j5LkXgzMeytX9UV4/dvE559292 rigid:1FsmFuY/NiNbzkTHdP5kqynoDn0 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6CTI2 uniprotkb:Q6CL77 intact:EBI-15928212|ensemblfungi:CAH01608 intact:EBI-15928255|ensemblfungi:CAG98020 psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928273|imex:IM-21304-1|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false sufficient binding region:103-184 sufficient binding region:41-115 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6CTI2 uniprotkb:Q6CMU6 intact:EBI-15928212|ensemblfungi:CAH01608 intact:EBI-15928236|ensemblfungi:CAG99830|ensemblfungi:CAR56747 psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:q6cmu6_klula(display_long)|uniprotkb:KLLA0_E08647g(orf name)|uniprotkb:KLLA0_E17601g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928273|imex:IM-21304-1|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N ensemblfungi:CAG99830(transcript)|ensemblfungi:CAR56747(transcript)|ensemblfungi:KLLA0_E08647g(gene)|ensemblfungi:KLLA0_E17601g(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:2YFV|rcsb pdb:2YFW|rcsb pdb:6UPH|refseq:XP_002999409.1|refseq:XP_454743.1|dip:DIP-60346N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rogid:GiKKMCO2HDsHIqqbZMoewz6ELEU284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false sufficient binding region:103-184 sufficient binding region:22-103 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6CL77 uniprotkb:Q6CMU6 intact:EBI-15928255|ensemblfungi:CAG98020 intact:EBI-15928236|ensemblfungi:CAG99830|ensemblfungi:CAR56747 psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:q6cmu6_klula(display_long)|uniprotkb:KLLA0_E08647g(orf name)|uniprotkb:KLLA0_E17601g(orf name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15928315|imex:IM-21304-3|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N ensemblfungi:CAG99830(transcript)|ensemblfungi:CAR56747(transcript)|ensemblfungi:KLLA0_E08647g(gene)|ensemblfungi:KLLA0_E17601g(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:2YFV|rcsb pdb:2YFW|rcsb pdb:6UPH|refseq:XP_002999409.1|refseq:XP_454743.1|dip:DIP-60346N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rogid:GiKKMCO2HDsHIqqbZMoewz6ELEU284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6CL77 uniprotkb:Q6CTI2 intact:EBI-15928255|ensemblfungi:CAG98020 intact:EBI-15928212|ensemblfungi:CAH01608 psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:"MI:0096"(pull down) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15928315|imex:IM-21304-3|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P36012 uniprotkb:P02309 intact:EBI-5182|uniprotkb:D6VXN8|ensemblfungi:YKL049C intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W psi-mi:cenpa_yeast(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CSL2(gene name synonym)|uniprotkb:YKL262(orf name)|uniprotkb:YKL049C(locus name) psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short) psi-mi:"MI:0028"(cosedimentation in solution) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928335|imex:IM-21304-4|dip:DIP-191285E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012875.2|sgd:S000001532|dip:DIP-8048N|ensemblfungi:YKL049C(gene)|ensemblfungi:YKL049C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030543"(2-micrometer plasmid partitioning)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2FSB|rcsb pdb:2FSC|rcsb pdb:2L5A|rcsb pdb:2LY8|rcsb pdb:6UPH|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214841|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-9018519 refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) crc64:0170A10060EEC309 crc64:69B7D1F89E62DE41 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:TR0UUGVelC2Gg5qjnGp3HSCrxbA559292 rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292 rigid:1FsmFuY/NiNbzkTHdP5kqynoDn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36012 uniprotkb:Q12334 intact:EBI-5182|uniprotkb:D6VXN8|ensemblfungi:YKL049C intact:EBI-31788|uniprotkb:D6VRK9|ensemblfungi:YDL139C psi-mi:cenpa_yeast(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CSL2(gene name synonym)|uniprotkb:YKL262(orf name)|uniprotkb:YKL049C(locus name) psi-mi:scm3_yeast(display_long)|uniprotkb:Suppressor of chromosome missegregation protein 3(gene name synonym)|uniprotkb:SCM3(gene name)|psi-mi:SCM3(display_short)|uniprotkb:YDL139C(locus name)|uniprotkb:D2155(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928335|imex:IM-21304-4|dip:DIP-191285E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012875.2|sgd:S000001532|dip:DIP-8048N|ensemblfungi:YKL049C(gene)|ensemblfungi:YKL049C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030543"(2-micrometer plasmid partitioning)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2FSB|rcsb pdb:2FSC|rcsb pdb:2L5A|rcsb pdb:2LY8|rcsb pdb:6UPH|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214841|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-9018519 refseq:NP_010142.2|sgd:S000002298|dip:DIP-5045N|mint:Q12334|ensemblfungi:YDL139C(gene)|ensemblfungi:YDL139C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2L5A psi-mi:"MI:0465"(dip) crc64:0170A10060EEC309 crc64:D7668117BCC7FF12 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:TR0UUGVelC2Gg5qjnGp3HSCrxbA559292 rogid:XeI5kq0j5LkXgzMeytX9UV4/dvE559292 rigid:1FsmFuY/NiNbzkTHdP5kqynoDn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CTI2 uniprotkb:Q6CL77 intact:EBI-15928212|ensemblfungi:CAH01608 intact:EBI-15928255|ensemblfungi:CAG98020 psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928375|imex:IM-21304-6|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CTI2 uniprotkb:Q6CMU6 intact:EBI-15928212|ensemblfungi:CAH01608 intact:EBI-15928236|ensemblfungi:CAG99830|ensemblfungi:CAR56747 psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:q6cmu6_klula(display_long)|uniprotkb:KLLA0_E08647g(orf name)|uniprotkb:KLLA0_E17601g(orf name) psi-mi:"MI:0071"(molecular sieving) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15928375|imex:IM-21304-6|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N ensemblfungi:CAG99830(transcript)|ensemblfungi:CAR56747(transcript)|ensemblfungi:KLLA0_E08647g(gene)|ensemblfungi:KLLA0_E17601g(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:2YFV|rcsb pdb:2YFW|rcsb pdb:6UPH|refseq:XP_002999409.1|refseq:XP_454743.1|dip:DIP-60346N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rogid:GiKKMCO2HDsHIqqbZMoewz6ELEU284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CMU6 uniprotkb:Q6CTI2 intact:EBI-15928236|ensemblfungi:CAG99830|ensemblfungi:CAR56747 intact:EBI-15928212|ensemblfungi:CAH01608 psi-mi:q6cmu6_klula(display_long)|uniprotkb:KLLA0_E08647g(orf name)|uniprotkb:KLLA0_E17601g(orf name) psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:"MI:0114"(x-ray crystallography) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928354|imex:IM-21304-5|dip:DIP-191287E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAG99830(transcript)|ensemblfungi:CAR56747(transcript)|ensemblfungi:KLLA0_E08647g(gene)|ensemblfungi:KLLA0_E17601g(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:2YFV|rcsb pdb:2YFW|rcsb pdb:6UPH|refseq:XP_002999409.1|refseq:XP_454743.1|dip:DIP-60346N ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:GiKKMCO2HDsHIqqbZMoewz6ELEU284590 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rigid:ItDZitOdrL9b39ESNdUvZyGobDI false sufficient binding region:22-103 sufficient binding region:103-184 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CTI2 uniprotkb:Q6CL77 intact:EBI-15928212|ensemblfungi:CAH01608 intact:EBI-15928255|ensemblfungi:CAG98020 psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:q6cl77_klula(display_long)|uniprotkb:KLLA0_F05115g(orf name) psi-mi:"MI:0114"(x-ray crystallography) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928394|imex:IM-21304-7|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N ensemblfungi:CAG98020(transcript)|ensemblfungi:KLLA0_F05115g(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0042393"(histone binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0097030"(CENP-A containing nucleosome binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR018465|rcsb pdb:2YFV|refseq:XP_455312.1|dip:DIP-59580N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rogid:YaD0XyMIUgY7sS3/3EK2EILpaps284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false sufficient binding region:103-184 sufficient binding region:41-115 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6CTI2 uniprotkb:Q6CMU6 intact:EBI-15928212|ensemblfungi:CAH01608 intact:EBI-15928236|ensemblfungi:CAG99830|ensemblfungi:CAR56747 psi-mi:cenpa_klula(display_long)|uniprotkb:CSE4(gene name)|psi-mi:CSE4(display_short)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Chromosome segregation protein 4(gene name synonym)|uniprotkb:KLLA0C12529g(locus name) psi-mi:q6cmu6_klula(display_long)|uniprotkb:KLLA0_E08647g(orf name)|uniprotkb:KLLA0_E17601g(orf name) psi-mi:"MI:0114"(x-ray crystallography) Cho et al. (2011) pubmed:21606327|doi:10.1073/pnas.1106389108|imex:IM-21304 taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15928394|imex:IM-21304-7|dip:DIP-191286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CAH01608(transcript)|ensemblfungi:KLLA0_C12529g(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005729"(2-micrometer circle DNA)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0061644"(protein localization to CENP-A containing chromatin)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2YFV|rcsb pdb:2YFW|go:"GO:0030543"(2-micrometer plasmid partitioning)|refseq:XP_452757.1|dip:DIP-60345N ensemblfungi:CAG99830(transcript)|ensemblfungi:CAR56747(transcript)|ensemblfungi:KLLA0_E08647g(gene)|ensemblfungi:KLLA0_E17601g(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:2YFV|rcsb pdb:2YFW|rcsb pdb:6UPH|refseq:XP_002999409.1|refseq:XP_454743.1|dip:DIP-60346N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:+MTbyt1sbmKBu59ghzUiRldCUPQ284590 rogid:GiKKMCO2HDsHIqqbZMoewz6ELEU284590 rigid:eUs/YgF2fEne3VP4Gl8L7pVQBdQ false sufficient binding region:103-184 sufficient binding region:22-103 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)