#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O08586 uniprotkb:Q19T08 intact:EBI-1186266|uniprotkb:Q542G1|uniprotkb:Q3UFB0|ensembl:ENSMUSP00000013807 intact:EBI-15778214|ensembl:ENSP00000479243|ensembl:ENSP00000500743|uniprotkb:B4E3H7|uniprotkb:C3RSF2 psi-mi:pten_mouse(display_long)|uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)|uniprotkb:Pten(gene name)|psi-mi:Pten(display_short)|uniprotkb:Mmac1(gene name synonym)|uniprotkb:Phosphatase and tensin homolog(gene name synonym) psi-mi:ecscr_human(display_long)|uniprotkb:ECSCR(gene name)|psi-mi:ECSCR(display_short)|uniprotkb:Apoptosis regulator through modulating IAP expression(gene name synonym)|uniprotkb:ECSM2(gene name synonym)|uniprotkb:Endothelial cell-specific molecule 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koide et al. (2011) pubmed:21593423|doi:10.1073/pnas.1101296108|imex:IM-21302 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15927558|imex:IM-21302-2|dip:DIP-191283E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032986.1|ensembl:ENSMUSG00000013663(gene)|ensembl:ENSMUST00000013807(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002902"(regulation of B cell apoptotic process)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016314"(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032355"(response to estradiol)|go:"GO:0032535"(regulation of cellular component size)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033198"(response to ATP)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042493"|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051548"(negative regulation of keratinocyte migration)|go:"GO:0051717"(inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051800"(phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060074"(synapse maturation)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060179"(male mating behavior)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000808"(negative regulation of synaptic vesicle clustering)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR014020(C2 tensin-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017361(Bifunctional phosphatidylinositol trisphosphate phosphatase/dual-specificity phosphatase PTEN)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|mint:O08586|reactome:R-MMU-1660499|reactome:R-MMU-1855204|reactome:R-MMU-199418|reactome:R-MMU-202424|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-8948747|reactome:R-MMU-8948751|dip:DIP-38740N ensembl:ENSG00000249751(gene)|ensembl:ENSG00000288297(gene)|ensembl:ENST00000618155(transcript)|ensembl:ENST00000673382(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR026247|refseq:NP_001071161.1|refseq:NP_001280668.1|dip:DIP-60344N psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:7CB22DEF4B6ADCAD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:aYdg7gklHYpORXuGG/JEOr/l/uo10090 rogid:+8RyLdCgu7OTshsNCqDkexxmX709606 rigid:iHbgBeaMeUE6uTzXKr3NMsqxtk8 false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P60484-1 uniprotkb:Q19T08 intact:EBI-15722967|ensembl:ENSP00000361021 intact:EBI-15778214|ensembl:ENSP00000479243|ensembl:ENSP00000500743|uniprotkb:B4E3H7|uniprotkb:C3RSF2 psi-mi:p60484-1(display_long)|uniprotkb:PTEN(gene name)|psi-mi:PTEN(display_short)|uniprotkb:MMAC1(gene name synonym)|uniprotkb:TEP1(gene name synonym)|uniprotkb:55kDa(isoform synonym)|uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)|uniprotkb:Phosphatase and tensin homolog(gene name synonym) psi-mi:ecscr_human(display_long)|uniprotkb:ECSCR(gene name)|psi-mi:ECSCR(display_short)|uniprotkb:Apoptosis regulator through modulating IAP expression(gene name synonym)|uniprotkb:ECSM2(gene name synonym)|uniprotkb:Endothelial cell-specific molecule 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koide et al. (2011) pubmed:21593423|doi:10.1073/pnas.1101296108|imex:IM-21302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15927535|imex:IM-21302-1|dip:DIP-191284E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-696162(isoform-parent)|ensembl:ENSG00000171862(gene)|ensembl:ENST00000371953(transcript) ensembl:ENSG00000249751(gene)|ensembl:ENSG00000288297(gene)|ensembl:ENST00000618155(transcript)|ensembl:ENST00000673382(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR026247|refseq:NP_001071161.1|refseq:NP_001280668.1|dip:DIP-60344N psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:7CB22DEF4B6ADCAD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/07 2017/08/10 rogid:/cPQox/hRcR/ED//46U5w4lcsyc9606 rogid:+8RyLdCgu7OTshsNCqDkexxmX709606 rigid:NG3DX6pdLIrm7G6EYL1MuN1O+54 false sufficient binding region:1-353|ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P60484-1 uniprotkb:Q19T08 intact:EBI-15722967|ensembl:ENSP00000361021 intact:EBI-15778214|ensembl:ENSP00000479243|ensembl:ENSP00000500743|uniprotkb:B4E3H7|uniprotkb:C3RSF2 psi-mi:p60484-1(display_long)|uniprotkb:PTEN(gene name)|psi-mi:PTEN(display_short)|uniprotkb:MMAC1(gene name synonym)|uniprotkb:TEP1(gene name synonym)|uniprotkb:55kDa(isoform synonym)|uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)|uniprotkb:Phosphatase and tensin homolog(gene name synonym) psi-mi:ecscr_human(display_long)|uniprotkb:ECSCR(gene name)|psi-mi:ECSCR(display_short)|uniprotkb:Apoptosis regulator through modulating IAP expression(gene name synonym)|uniprotkb:ECSM2(gene name synonym)|uniprotkb:Endothelial cell-specific molecule 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koide et al. (2011) pubmed:21593423|doi:10.1073/pnas.1101296108|imex:IM-21302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15927598|imex:IM-21302-4|dip:DIP-191284E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-696162(isoform-parent)|ensembl:ENSG00000171862(gene)|ensembl:ENST00000371953(transcript) ensembl:ENSG00000249751(gene)|ensembl:ENSG00000288297(gene)|ensembl:ENST00000618155(transcript)|ensembl:ENST00000673382(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR026247|refseq:NP_001071161.1|refseq:NP_001280668.1|dip:DIP-60344N psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:7CB22DEF4B6ADCAD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/07 2017/08/10 rogid:/cPQox/hRcR/ED//46U5w4lcsyc9606 rogid:+8RyLdCgu7OTshsNCqDkexxmX709606 rigid:NG3DX6pdLIrm7G6EYL1MuN1O+54 false sufficient binding region:1-353|ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P60484-1 uniprotkb:Q19T08 intact:EBI-15722967|ensembl:ENSP00000361021 intact:EBI-15778214|ensembl:ENSP00000479243|ensembl:ENSP00000500743|uniprotkb:B4E3H7|uniprotkb:C3RSF2 psi-mi:p60484-1(display_long)|uniprotkb:PTEN(gene name)|psi-mi:PTEN(display_short)|uniprotkb:MMAC1(gene name synonym)|uniprotkb:TEP1(gene name synonym)|uniprotkb:55kDa(isoform synonym)|uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)|uniprotkb:Phosphatase and tensin homolog(gene name synonym) psi-mi:ecscr_human(display_long)|uniprotkb:ECSCR(gene name)|psi-mi:ECSCR(display_short)|uniprotkb:Apoptosis regulator through modulating IAP expression(gene name synonym)|uniprotkb:ECSM2(gene name synonym)|uniprotkb:Endothelial cell-specific molecule 2(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Koide et al. (2011) pubmed:21593423|doi:10.1073/pnas.1101296108|imex:IM-21302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15927577|imex:IM-21302-3|dip:DIP-191284E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-696162(isoform-parent)|ensembl:ENSG00000171862(gene)|ensembl:ENST00000371953(transcript) ensembl:ENSG00000249751(gene)|ensembl:ENSG00000288297(gene)|ensembl:ENST00000618155(transcript)|ensembl:ENST00000673382(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR026247|refseq:NP_001071161.1|refseq:NP_001280668.1|dip:DIP-60344N psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:7CB22DEF4B6ADCAD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/07 2017/08/10 rogid:/cPQox/hRcR/ED//46U5w4lcsyc9606 rogid:+8RyLdCgu7OTshsNCqDkexxmX709606 rigid:NG3DX6pdLIrm7G6EYL1MuN1O+54 false kusabira-green protein tag:n-n kusabira-green protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60484-1 uniprotkb:Q19T08 intact:EBI-15722967|ensembl:ENSP00000361021 intact:EBI-15778214|ensembl:ENSP00000479243|ensembl:ENSP00000500743|uniprotkb:B4E3H7|uniprotkb:C3RSF2 psi-mi:p60484-1(display_long)|uniprotkb:PTEN(gene name)|psi-mi:PTEN(display_short)|uniprotkb:MMAC1(gene name synonym)|uniprotkb:TEP1(gene name synonym)|uniprotkb:55kDa(isoform synonym)|uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)|uniprotkb:Phosphatase and tensin homolog(gene name synonym) psi-mi:ecscr_human(display_long)|uniprotkb:ECSCR(gene name)|psi-mi:ECSCR(display_short)|uniprotkb:Apoptosis regulator through modulating IAP expression(gene name synonym)|uniprotkb:ECSM2(gene name synonym)|uniprotkb:Endothelial cell-specific molecule 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koide et al. (2011) pubmed:21593423|doi:10.1073/pnas.1101296108|imex:IM-21302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15927621|imex:IM-21302-5|dip:DIP-191284E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-696162(isoform-parent)|ensembl:ENSG00000171862(gene)|ensembl:ENST00000371953(transcript) ensembl:ENSG00000249751(gene)|ensembl:ENSG00000288297(gene)|ensembl:ENST00000618155(transcript)|ensembl:ENST00000673382(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR026247|refseq:NP_001071161.1|refseq:NP_001280668.1|dip:DIP-60344N psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:7CB22DEF4B6ADCAD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/07 2017/08/10 rogid:/cPQox/hRcR/ED//46U5w4lcsyc9606 rogid:+8RyLdCgu7OTshsNCqDkexxmX709606 rigid:NG3DX6pdLIrm7G6EYL1MuN1O+54 false ha tag:n-n flag tag:c-c|sufficient binding region:146-205 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)