#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62991 uniprotkb:Q9QZH6 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N intact:EBI-527020|uniprotkb:Q91V53 psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15923356|imex:IM-16218-1|dip:DIP-187249E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rigid:2YU9nky1kmBpx2zbh9MOPBoVr8Q false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70196 uniprotkb:Q9QZH6 intact:EBI-448028|ensembl:ENSMUSP00000004949|uniprotkb:Q8BLV2|uniprotkb:Q6P9M0 intact:EBI-527020|uniprotkb:Q91V53 psi-mi:traf6_mouse(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)|uniprotkb:Traf6(gene name)|psi-mi:Traf6(display_short)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym) psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15923373|imex:IM-16218-2|dip:DIP-78837E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027164(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|ensembl:ENSMUST00000004949(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|refseq:NP_033450.2|refseq:NP_001290202.1|go:"GO:0001843"(neural tube closure)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|dip:DIP-29812N|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:P70196|reactome:R-MMU-1257604|reactome:R-MMU-166058|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|reactome:R-MMU-168638|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-205043|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-5607764|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-6811558|reactome:R-MMU-9020702|reactome:R-MMU-937039|reactome:R-MMU-937041|reactome:R-MMU-937042|reactome:R-MMU-937072|reactome:R-MMU-9645460|reactome:R-MMU-975138|go:"GO:0046330"(positive regulation of JNK cascade)|reactome:R-MMU-975144|reactome:R-MMU-975163|reactome:R-MMU-975871|go:"GO:0046849"(bone remodeling)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:ugYIdBBXOfQsUJo4CPEuVY1hzm810090 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rigid:vuhPXY9OzGnJftEFCLbDfTJvfVE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62991 uniprotkb:Q9QZH6 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N intact:EBI-527020|uniprotkb:Q91V53 psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15923390|imex:IM-16218-3|dip:DIP-187249E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 psi-mi:"MI:0465"(dip) - - comment:Deletion of region 1-260 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rigid:2YU9nky1kmBpx2zbh9MOPBoVr8Q false ha tag:0-0 flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9QZH6 uniprotkb:Q8JZN5 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-8369678|intact:MINT-4086603|uniprotkb:Q8BK76|uniprotkb:Q8C0B5|uniprotkb:Q3ULL9|ensembl:ENSMUSP00000011492 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:acad9_mouse(display_long)|uniprotkb:Acad9(gene name)|psi-mi:Acad9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923428|imex:IM-16218-4|dip:DIP-187250E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_766266.3|dip:DIP-59192N|ensembl:ENSMUSG00000027710(gene)|ensembl:ENSMUST00000011492(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q8JZN5|reactome:R-MMU-6799198 psi-mi:"MI:0465"(dip) - comment:mint|function:"Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA then on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0)" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:j4KumzEMeLE5MRemyIYKdtFNj1010090 rigid:VDgqr/XAkKFxuMITRzKD+I7zJDM false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:Q9CWX2 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-15923412|uniprotkb:Q8VEI8 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:cia30_mouse(display_long)|uniprotkb:Ndufaf1(gene name)|psi-mi:Ndufaf1(display_short)|uniprotkb:Cia30(gene name synonym)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923428|imex:IM-16218-4|dip:DIP-187250E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|go:"GO:0005739"(mitochondrion)|reactome:R-MMU-6799198|refseq:NP_081451.3|refseq:XP_006500212.1|dip:DIP-59193N|refseq:XP_006500211.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:FYROqR6RxMcMRQ4qUMk+KD7IA6o10090 rigid:VDgqr/XAkKFxuMITRzKD+I7zJDM false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:Q925I1 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-772703|uniprotkb:Q3UE74|uniprotkb:Q69ZM7|uniprotkb:Q8C6C6|uniprotkb:A2AD89|uniprotkb:Q3TA78|ensembl:ENSMUSP00000030903 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:atad3_mouse(display_long)|uniprotkb:AAA-ATPase TOB3(gene name synonym)|uniprotkb:Atad3(gene name)|psi-mi:Atad3(display_short)|uniprotkb:Atad3a(gene name synonym)|uniprotkb:Kiaa1273(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923428|imex:IM-16218-4|dip:DIP-187250E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_849534.2|dip:DIP-32373N|ensembl:ENSMUSG00000029036(gene)|ensembl:ENSMUST00000030903(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q925I1|reactome:R-MMU-6798695 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:ftt3s2Khsm5F0iodev1GLQFMHqg10090 rigid:VDgqr/XAkKFxuMITRzKD+I7zJDM false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:P63038 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923428|imex:IM-16218-4|dip:DIP-187250E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090 rigid:VDgqr/XAkKFxuMITRzKD+I7zJDM false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:P51881 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-445370|uniprotkb:Q61311|ensembl:ENSMUSP00000016463 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:adt2_mouse(display_long)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:Slc25a5(gene name)|psi-mi:Slc25a5(display_short)|uniprotkb:Ant2(gene name synonym)|uniprotkb:Aac2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923428|imex:IM-16218-4|dip:DIP-187250E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_031477.1|dip:DIP-31399N|ensembl:ENSMUSG00000016319(gene)|ensembl:ENSMUST00000016463(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P51881|reactome:R-MMU-83936|go:"GO:0031625"(ubiquitin protein ligase binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:146+I0bORlUf6z9chvmdXwUCtOs10090 rigid:VDgqr/XAkKFxuMITRzKD+I7zJDM false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:Q00325 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 psi-mi:"MI:0465"(dip) - crc64:78714C85931B22D5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:O75489 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 psi-mi:"MI:0465"(dip) - crc64:C058D62779BEF17B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:P25705 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:Q9NVI7 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:IZKJEVLLS/DFINgBgO5frizN1P49606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:Q9H845 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:P10809 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QZH6 uniprotkb:P05141 intact:EBI-527020|uniprotkb:Q91V53 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:ecsit_mouse(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:Ecsit(gene name)|psi-mi:Ecsit(display_short)|uniprotkb:Sitpec(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) West et al. (2011) pubmed:21525932|doi:10.1038/nature09973|imex:IM-16218 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15923451|imex:IM-16218-5|dip:DIP-187251E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036159.1|refseq:XP_011240840.1|refseq:XP_006510433.1|refseq:NP_001240826.1|refseq:NP_001240827.1|go:"GO:0005739"(mitochondrion)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005829"(cytosol)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|dip:DIP-33901N|reactome:R-MMU-166058|reactome:R-MMU-6799198|reactome:R-MMU-975138|reactome:R-MMU-975871 refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:OJosVT4SJO/B9WEMImjhVyFef3Q10090 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 rigid:kUGnb+uq2pZFi4nN4kxKHidj36c false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)